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The map label for this gene is queC

Identifier: 83313120

GI number: 83313120

Start: 4430335

End: 4431018

Strand: Reverse

Name: queC

Synonym: amb4021

Alternate gene names: 83313120

Gene position: 4431018-4430335 (Counterclockwise)

Preceding gene: 83313121

Following gene: 83313117

Centisome position: 89.21

GC content: 68.27

Gene sequence:

>684_bases
ATGAAGCCCGCCATCGTCCTGCTCAGCGGCGGCCTTGATTCCGCCACGGTGCTGGCCATCGCCAAGGCCGAGGGCTTTGC
CCCGGCGGCGCTGACCTTCCGCTACGGCCAGCGCCACGCGGTGGAGATCCGGGCGGCCGAGCGGGTGGCGGCGGCTCTGG
GCATCCGCGATCACCGCATCGCCGACATCGACCTGCGGGTCTTCGGCGGCTCGGCGCTGACCTCGGATATCGCCGTGCCC
AAGGGTGAGCTGGACGAGGCCATCCCCGCCGGCATCCCCGTCACCTATGTGCCGGCCCGCAACACCATCATGCTGTCCTT
CGCCCTGGCCTTCGCCGAGGTTCTGGGCGCCGCCGACATCTTCGTCGGCGTCAACGCCGTGGATTATTCCGGCTATCCCG
ATTGCCGCCCCGACTATATCAAGGCCTTCGAGGCCATGGCCAATCTGGCCACCAAGGCGGCGGTGGAGGGGACGCGGCTG
ACCATCCACACCCCGCTGATCGACCTGACCAAGGGACAGATCATCCGGCGCGGGCTGGACCTGGGCGTGGATTATTCCAT
CACGTCGACCTGCTACGACCCCACTCCGGACGGCAAGGCTTGCGGCCATTGCGATTCCTGCCGCCTGCGGCTCAAGGGCT
TCGCCGAGGCCGGTCTGGCCGATCCGGCCGAATACGCCTCCTGA

Upstream 100 bases:

>100_bases
CCAACGTGGATATCACCAAGCTGCGGTCCGATCTGGCCGCCAAGGGCTGGTCCGAGGCCGAGATCGATTCCTTCATCGCG
TCGCATTTCTCGCTGTAGTC

Downstream 100 bases:

>100_bases
TCCGGATCAGTGTTCCAGCCAGGCCTGGAACATCAGGGCGTGCCACATCTCGTTCTGCCAGTTCTTGGCCCCCGAGCGGT
GCTCGCGCCAGCACTGGGCG

Product: PP-loop superfamily ATPase

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MKPAIVLLSGGLDSATVLAIAKAEGFAPAALTFRYGQRHAVEIRAAERVAAALGIRDHRIADIDLRVFGGSALTSDIAVP
KGELDEAIPAGIPVTYVPARNTIMLSFALAFAEVLGAADIFVGVNAVDYSGYPDCRPDYIKAFEAMANLATKAAVEGTRL
TIHTPLIDLTKGQIIRRGLDLGVDYSITSTCYDPTPDGKACGHCDSCRLRLKGFAEAGLADPAEYAS

Sequences:

>Translated_227_residues
MKPAIVLLSGGLDSATVLAIAKAEGFAPAALTFRYGQRHAVEIRAAERVAAALGIRDHRIADIDLRVFGGSALTSDIAVP
KGELDEAIPAGIPVTYVPARNTIMLSFALAFAEVLGAADIFVGVNAVDYSGYPDCRPDYIKAFEAMANLATKAAVEGTRL
TIHTPLIDLTKGQIIRRGLDLGVDYSITSTCYDPTPDGKACGHCDSCRLRLKGFAEAGLADPAEYAS
>Mature_227_residues
MKPAIVLLSGGLDSATVLAIAKAEGFAPAALTFRYGQRHAVEIRAAERVAAALGIRDHRIADIDLRVFGGSALTSDIAVP
KGELDEAIPAGIPVTYVPARNTIMLSFALAFAEVLGAADIFVGVNAVDYSGYPDCRPDYIKAFEAMANLATKAAVEGTRL
TIHTPLIDLTKGQIIRRGLDLGVDYSITSTCYDPTPDGKACGHCDSCRLRLKGFAEAGLADPAEYAS

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family

Homologues:

Organism=Escherichia coli, GI1786648, Length=221, Percent_Identity=36.6515837104072, Blast_Score=122, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QUEC_MAGSA (Q2W000)

Other databases:

- EMBL:   AP007255
- RefSeq:   YP_423384.1
- ProteinModelPortal:   Q2W000
- SMR:   Q2W000
- STRING:   Q2W000
- GeneID:   3806561
- GenomeReviews:   AP007255_GR
- KEGG:   mag:amb4021
- NMPDR:   fig|342108.5.peg.3614
- eggNOG:   COG0603
- HOGENOM:   HBG553284
- OMA:   GWAEVLG
- PhylomeDB:   Q2W000
- BioCyc:   MMAG342108:AMB4021-MONOMER
- HAMAP:   MF_01633_B
- InterPro:   IPR018317
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PIRSF:   PIRSF006293
- TIGRFAMs:   TIGR00364

Pfam domain/function: PF06508 ExsB

EC number: NA

Molecular weight: Translated: 23898; Mature: 23898

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPAIVLLSGGLDSATVLAIAKAEGFAPAALTFRYGQRHAVEIRAAERVAAALGIRDHRI
CCCEEEEEECCCCCEEEEEEEECCCCCCEEEEEECCCCEEEEEHHHHHHHHHHCCCCCEE
ADIDLRVFGGSALTSDIAVPKGELDEAIPAGIPVTYVPARNTIMLSFALAFAEVLGAADI
EEEEEEEECCCHHCCCCCCCCCCCHHHCCCCCCEEEECCCCEEHHHHHHHHHHHHCCHHE
FVGVNAVDYSGYPDCRPDYIKAFEAMANLATKAAVEGTRLTIHTPLIDLTKGQIIRRGLD
EEECEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCEEECCHHHHHHHHCC
LGVDYSITSTCYDPTPDGKACGHCDSCRLRLKGFAEAGLADPAEYAS
CCCCEEEECCCCCCCCCCCCCCCCHHHHEEEECCHHCCCCCCHHHCC
>Mature Secondary Structure
MKPAIVLLSGGLDSATVLAIAKAEGFAPAALTFRYGQRHAVEIRAAERVAAALGIRDHRI
CCCEEEEEECCCCCEEEEEEEECCCCCCEEEEEECCCCEEEEEHHHHHHHHHHCCCCCEE
ADIDLRVFGGSALTSDIAVPKGELDEAIPAGIPVTYVPARNTIMLSFALAFAEVLGAADI
EEEEEEEECCCHHCCCCCCCCCCCHHHCCCCCCEEEECCCCEEHHHHHHHHHHHHCCHHE
FVGVNAVDYSGYPDCRPDYIKAFEAMANLATKAAVEGTRLTIHTPLIDLTKGQIIRRGLD
EEECEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCEEECCHHHHHHHHCC
LGVDYSITSTCYDPTPDGKACGHCDSCRLRLKGFAEAGLADPAEYAS
CCCCEEEECCCCCCCCCCCCCCCCHHHHEEEECCHHCCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA