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The map label for this gene is ccrMIM [H]

Identifier: 83313087

GI number: 83313087

Start: 4398261

End: 4399337

Strand: Reverse

Name: ccrMIM [H]

Synonym: amb3988

Alternate gene names: 83313087

Gene position: 4399337-4398261 (Counterclockwise)

Preceding gene: 83313088

Following gene: 83313086

Centisome position: 88.57

GC content: 65.09

Gene sequence:

>1077_bases
ATGACCCTGCCTCTCAACACCATTCTCTCCGGCGACTGCATCGCCATGATGAACTCCCTGCCCGCCGGTTCGGTGGATCT
GATCTTCGCGGATCCGCCCTATAACCTGCAGCTGGGCGGCGAGCTTCTGCGTCCCAACAACTCCAAGGTGGAGGGTGTGG
ACGAGGAGTGGGACCGCTTCTCGGATTTCGCGGCCTATGACAGCTTCACCCGCGACTGGCTGAAGGCGGCGCGCCGGGTG
CTGAAGGACGATGGCGGGCTGTGGGTGATCGGCAGCTACCACAACATCTTCCGCGTCGGCTCGATCCTCCAGGATCTGGG
GTTCTGGATGCTGAACGACATCGTCTGGCGCAAGAGCAATCCCATGCCCAATTTCAAGGGCACCCGCTTCACCAACGCCC
ACGAGACCATGATCTGGTGCGCCAAGTCGTCGGACTCCCGCTACACCTTCAACTACGACACCATGAAGGCGCTGAACGAC
GATCTGCAGATGCGCAGCGACTGGACCTTGCCGCTGTGCACCGGGGGCGAGCGCCTGAGGAATGCCGGGCGCAAGACCCA
TCCCACCCAGAAGCCGGAATCCCTGCTGTACCGCGTCATCATGGCCTCGACCAAGCCGGGCGACGTGGTGCTGGACCCCT
TCTTCGGCACCGGCACCACCGGGGCGGTGGCCAAGAAGCTGGGCCGCAACTTCATCGGCTGCGAGCGTGATCCCGAATAC
ATCGCCGCCGCCAAGGATCGCATCGCCAAGGTGATTCCGGTGGCCGATCCCTCCTTGCTGCTGACGCCGTCCAAGCGGGC
CGAGCCGCGGGTTCCGTTCGGCACCGTGCTGGAGCGCGGGCTGCTCACCGCCGGCGACCTGCTGTTCGGCGGCACCCGGC
ACGACAAGGTCGCCAAGGTGCGGGCCGACGGCACCCTGATCACCGATGACCATCGCGGCTCGATTCACAAGGTGGGCGCC
CTGGTCCAGGGCGCGCCGGCCTGCAACGGCTGGACCTACTGGCACTTCCAGGCTTCGTCCGAGGACTTCCTGCCCATCGA
CGTGCTGCGCCAGAAGATCCGGGCAGAGCTGCATTGA

Upstream 100 bases:

>100_bases
CACTACCTGTGGCAATGAATCATTAGATTCCAACAGGTTCTTGACGGACTCTCATGTTTGACTCAAATTGAGTGCTCCAA
CTCATTTGAATCGGTCCGCC

Downstream 100 bases:

>100_bases
TGCAGATGAACCATGGGTCCAGCGGCATCCTGCCGCCATTGCCCTTAGGCCCGGGCGGACCACGGTCCGCAGGGAGGCGG
CGGCCAAGCGCCCGGAGGGG

Product: modification methylase CcrMI

Products: NA

Alternate protein names: M.CcrMI; Adenine-specific methyltransferase CcrMI [H]

Number of amino acids: Translated: 358; Mature: 357

Protein sequence:

>358_residues
MTLPLNTILSGDCIAMMNSLPAGSVDLIFADPPYNLQLGGELLRPNNSKVEGVDEEWDRFSDFAAYDSFTRDWLKAARRV
LKDDGGLWVIGSYHNIFRVGSILQDLGFWMLNDIVWRKSNPMPNFKGTRFTNAHETMIWCAKSSDSRYTFNYDTMKALND
DLQMRSDWTLPLCTGGERLRNAGRKTHPTQKPESLLYRVIMASTKPGDVVLDPFFGTGTTGAVAKKLGRNFIGCERDPEY
IAAAKDRIAKVIPVADPSLLLTPSKRAEPRVPFGTVLERGLLTAGDLLFGGTRHDKVAKVRADGTLITDDHRGSIHKVGA
LVQGAPACNGWTYWHFQASSEDFLPIDVLRQKIRAELH

Sequences:

>Translated_358_residues
MTLPLNTILSGDCIAMMNSLPAGSVDLIFADPPYNLQLGGELLRPNNSKVEGVDEEWDRFSDFAAYDSFTRDWLKAARRV
LKDDGGLWVIGSYHNIFRVGSILQDLGFWMLNDIVWRKSNPMPNFKGTRFTNAHETMIWCAKSSDSRYTFNYDTMKALND
DLQMRSDWTLPLCTGGERLRNAGRKTHPTQKPESLLYRVIMASTKPGDVVLDPFFGTGTTGAVAKKLGRNFIGCERDPEY
IAAAKDRIAKVIPVADPSLLLTPSKRAEPRVPFGTVLERGLLTAGDLLFGGTRHDKVAKVRADGTLITDDHRGSIHKVGA
LVQGAPACNGWTYWHFQASSEDFLPIDVLRQKIRAELH
>Mature_357_residues
TLPLNTILSGDCIAMMNSLPAGSVDLIFADPPYNLQLGGELLRPNNSKVEGVDEEWDRFSDFAAYDSFTRDWLKAARRVL
KDDGGLWVIGSYHNIFRVGSILQDLGFWMLNDIVWRKSNPMPNFKGTRFTNAHETMIWCAKSSDSRYTFNYDTMKALNDD
LQMRSDWTLPLCTGGERLRNAGRKTHPTQKPESLLYRVIMASTKPGDVVLDPFFGTGTTGAVAKKLGRNFIGCERDPEYI
AAAKDRIAKVIPVADPSLLLTPSKRAEPRVPFGTVLERGLLTAGDLLFGGTRHDKVAKVRADGTLITDDHRGSIHKVGAL
VQGAPACNGWTYWHFQASSEDFLPIDVLRQKIRAELH

Specific function: This methylase recognizes the double-stranded sequence GANTC and causes specific methylation on A-2 on both strands. Ccrm-mediated methylation has important cellular functions. Appears to contribute to the accurate cell-cycle control of DNA replication an

COG id: COG0863

COG function: function code L; DNA modification methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI87082238, Length=266, Percent_Identity=33.4586466165414, Blast_Score=118, Evalue=5e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002941
- InterPro:   IPR002052
- InterPro:   IPR001091 [H]

Pfam domain/function: PF01555 N6_N4_Mtase [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 39917; Mature: 39786

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLPLNTILSGDCIAMMNSLPAGSVDLIFADPPYNLQLGGELLRPNNSKVEGVDEEWDRF
CCCCCHHHHCCCHHHHHHCCCCCCEEEEECCCCCCEEECCEEECCCCCCCCCCCHHHHHH
SDFAAYDSFTRDWLKAARRVLKDDGGLWVIGSYHNIFRVGSILQDLGFWMLNDIVWRKSN
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCC
PMPNFKGTRFTNAHETMIWCAKSSDSRYTFNYDTMKALNDDLQMRSDWTLPLCTGGERLR
CCCCCCCCEECCCCCEEEEEECCCCCEEEECHHHHHHHHHHHHHCCCCCCEEECCHHHHH
NAGRKTHPTQKPESLLYRVIMASTKPGDVVLDPFFGTGTTGAVAKKLGRNFIGCERDPEY
HCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHCCCCCCCCCCHHH
IAAAKDRIAKVIPVADPSLLLTPSKRAEPRVPFGTVLERGLLTAGDLLFGGTRHDKVAKV
HHHHHHHHHEEEECCCCCEEECCCCCCCCCCCHHHHHHHCCCCCCHHEECCCCCCCEEEE
RADGTLITDDHRGSIHKVGALVQGAPACNGWTYWHFQASSEDFLPIDVLRQKIRAELH
ECCCCEEECCCCCCHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
TLPLNTILSGDCIAMMNSLPAGSVDLIFADPPYNLQLGGELLRPNNSKVEGVDEEWDRF
CCCCHHHHCCCHHHHHHCCCCCCEEEEECCCCCCEEECCEEECCCCCCCCCCCHHHHHH
SDFAAYDSFTRDWLKAARRVLKDDGGLWVIGSYHNIFRVGSILQDLGFWMLNDIVWRKSN
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCC
PMPNFKGTRFTNAHETMIWCAKSSDSRYTFNYDTMKALNDDLQMRSDWTLPLCTGGERLR
CCCCCCCCEECCCCCEEEEEECCCCCEEEECHHHHHHHHHHHHHCCCCCCEEECCHHHHH
NAGRKTHPTQKPESLLYRVIMASTKPGDVVLDPFFGTGTTGAVAKKLGRNFIGCERDPEY
HCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHCCCCCCCCCCHHH
IAAAKDRIAKVIPVADPSLLLTPSKRAEPRVPFGTVLERGLLTAGDLLFGGTRHDKVAKV
HHHHHHHHHEEEECCCCCEEECCCCCCCCCCCHHHHHHHCCCCCCHHEECCCCCCCEEEE
RADGTLITDDHRGSIHKVGALVQGAPACNGWTYWHFQASSEDFLPIDVLRQKIRAELH
ECCCCEEECCCCCCHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8289276 [H]