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The map label for this gene is etfA [H]

Identifier: 83313002

GI number: 83313002

Start: 4318572

End: 4319507

Strand: Reverse

Name: etfA [H]

Synonym: amb3903

Alternate gene names: 83313002

Gene position: 4319507-4318572 (Counterclockwise)

Preceding gene: 83313003

Following gene: 83313001

Centisome position: 86.96

GC content: 68.27

Gene sequence:

>936_bases
ATGACCATTCTGGTTATCGCGGAACATGAAGGCGGCGCTCTCAAATCCGCCACGCTGAACACCGTTTCCGCCGCTTCCAA
GATCGGCGGCGACGTGCATGTGCTGGTGGCCGGCTCGGGCATCGGCGCGGTGGCCGAGGCCGCCGCCAAGGTGGCGGGCG
TCGCCAAGGTGCTGTCGGCCGACGCCGCCCTTTACGCCAACCATCTGGCCGAGCCGCTGGCCGCCCTGGTGGTGAGCCTT
GCCGGGTCCTATTCCCACATCCTGGCGCCGGCCACCACGGGGGGCAAGAACGTGGCGCCCCGCGTCGCCGCCCTGCTGGA
CGTGGCGCAGATCTCCGAGATCACCGCCGTGGTGTCGCCCGATACCTTCGTGCGGCCGATCTATGCCGGCAACGCCCTGG
CCACCGTGCAGTCCAAGGACGCGGTCAAGGTGATCACCGTGCGCGGCACCGGCTTTGAGGCCGCCAAGGCCGAGGGCGGC
TCCGCGTCGGTGGAAGCCGTGTCGGCCGCCGCCGATCCGGCCCTGTCGTCCTTCGTCGGCAGCCAGCTGTCCAAGTCCGA
GCGTCCGGAACTGACCTCGGCCCGGATCATCATCTCGGGCGGTCGCGGCATGCAGTCGGGCGACAACTTCCACCTGCTGG
AAGCCGTGGCCGACAAGCTGGGCGCCGCAGTCGGTGCCTCGCGCGCCGCCGTGGACGCCGGCTTCGTGCCCAACGACTTC
CAGGTGGGCCAGACCGGCAAGATCGTCGCCCCCGACCTCTACATCGCCGTCGGCATCTCGGGCGCCATCCAGCACCTGGC
CGGCATGAAGGACTCCAAGGTCATCGTCGCCATCAACAAGGACGAAGAGGCCCCCATCTTCCAGGTCGCCGATTACGGTC
TGGTCGCGGATCTCTTCAAGGTGTTGCCGGAGCTGGCCTCCGAACTCAACAAGTAA

Upstream 100 bases:

>100_bases
TGCCCCAAACCCCCTTTGAATTCAAAAGGGGTCCGGGGTCTTCCCCGGTCGGGGTGCGGGGCGGAAGCCCCGACGTGGCC
AGGACAAGGAACGAAAAGAC

Downstream 100 bases:

>100_bases
CCGTCAACCTGCCCTACGGCTGAAGCCATAGTATCCGGGAGCCTCATAATGACTGCTATCAATAAGATCGGTGTTATCGG
CGCGGGCCAGATGGGCAATG

Product: electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MTILVIAEHEGGALKSATLNTVSAASKIGGDVHVLVAGSGIGAVAEAAAKVAGVAKVLSADAALYANHLAEPLAALVVSL
AGSYSHILAPATTGGKNVAPRVAALLDVAQISEITAVVSPDTFVRPIYAGNALATVQSKDAVKVITVRGTGFEAAKAEGG
SASVEAVSAAADPALSSFVGSQLSKSERPELTSARIIISGGRGMQSGDNFHLLEAVADKLGAAVGASRAAVDAGFVPNDF
QVGQTGKIVAPDLYIAVGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGLVADLFKVLPELASELNK

Sequences:

>Translated_311_residues
MTILVIAEHEGGALKSATLNTVSAASKIGGDVHVLVAGSGIGAVAEAAAKVAGVAKVLSADAALYANHLAEPLAALVVSL
AGSYSHILAPATTGGKNVAPRVAALLDVAQISEITAVVSPDTFVRPIYAGNALATVQSKDAVKVITVRGTGFEAAKAEGG
SASVEAVSAAADPALSSFVGSQLSKSERPELTSARIIISGGRGMQSGDNFHLLEAVADKLGAAVGASRAAVDAGFVPNDF
QVGQTGKIVAPDLYIAVGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGLVADLFKVLPELASELNK
>Mature_310_residues
TILVIAEHEGGALKSATLNTVSAASKIGGDVHVLVAGSGIGAVAEAAAKVAGVAKVLSADAALYANHLAEPLAALVVSLA
GSYSHILAPATTGGKNVAPRVAALLDVAQISEITAVVSPDTFVRPIYAGNALATVQSKDAVKVITVRGTGFEAAKAEGGS
ASVEAVSAAADPALSSFVGSQLSKSERPELTSARIIISGGRGMQSGDNFHLLEAVADKLGAAVGASRAAVDAGFVPNDFQ
VGQTGKIVAPDLYIAVGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGLVADLFKVLPELASELNK

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=312, Percent_Identity=61.5384615384615, Blast_Score=374, Evalue=1e-104,
Organism=Homo sapiens, GI189181759, Length=271, Percent_Identity=63.8376383763838, Blast_Score=337, Evalue=1e-92,
Organism=Escherichia coli, GI1786226, Length=228, Percent_Identity=33.7719298245614, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1787990, Length=257, Percent_Identity=32.6848249027237, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI87082157, Length=227, Percent_Identity=34.8017621145374, Blast_Score=92, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17506929, Length=311, Percent_Identity=58.5209003215434, Blast_Score=338, Evalue=2e-93,
Organism=Saccharomyces cerevisiae, GI6325261, Length=319, Percent_Identity=43.5736677115987, Blast_Score=253, Evalue=3e-68,
Organism=Drosophila melanogaster, GI17136898, Length=312, Percent_Identity=65.0641025641026, Blast_Score=374, Evalue=1e-104,
Organism=Drosophila melanogaster, GI24652801, Length=312, Percent_Identity=65.0641025641026, Blast_Score=374, Evalue=1e-104,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 31198; Mature: 31067

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTILVIAEHEGGALKSATLNTVSAASKIGGDVHVLVAGSGIGAVAEAAAKVAGVAKVLSA
CEEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHH
DAALYANHLAEPLAALVVSLAGSYSHILAPATTGGKNVAPRVAALLDVAQISEITAVVSP
HHHHHHHHHHHHHHHHHHHHCCCCHHEEEECCCCCCCHHHHHHHHHHHHHHHHHHEEECC
DTFVRPIYAGNALATVQSKDAVKVITVRGTGFEAAKAEGGSASVEAVSAAADPALSSFVG
CHHCCEEECCCEEEEEECCCCEEEEEEECCCCCHHCCCCCCCCHHHHHHHCCHHHHHHHH
SQLSKSERPELTSARIIISGGRGMQSGDNFHLLEAVADKLGAAVGASRAAVDAGFVPNDF
HHHCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHCCCCCCCCC
QVGQTGKIVAPDLYIAVGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGLVADLFK
EECCCCCEECCCEEEEECHHHHHHHHHCCCCCEEEEEECCCCCCCEEEECCHHHHHHHHH
VLPELASELNK
HHHHHHHHHCC
>Mature Secondary Structure 
TILVIAEHEGGALKSATLNTVSAASKIGGDVHVLVAGSGIGAVAEAAAKVAGVAKVLSA
EEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHH
DAALYANHLAEPLAALVVSLAGSYSHILAPATTGGKNVAPRVAALLDVAQISEITAVVSP
HHHHHHHHHHHHHHHHHHHHCCCCHHEEEECCCCCCCHHHHHHHHHHHHHHHHHHEEECC
DTFVRPIYAGNALATVQSKDAVKVITVRGTGFEAAKAEGGSASVEAVSAAADPALSSFVG
CHHCCEEECCCEEEEEECCCCEEEEEEECCCCCHHCCCCCCCCHHHHHHHCCHHHHHHHH
SQLSKSERPELTSARIIISGGRGMQSGDNFHLLEAVADKLGAAVGASRAAVDAGFVPNDF
HHHCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHCCCCCCCCC
QVGQTGKIVAPDLYIAVGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGLVADLFK
EECCCCCEECCCEEEEECHHHHHHHHHCCCCCEEEEEECCCCCCCEEEECCHHHHHHHHH
VLPELASELNK
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]