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The map label for this gene is mcpA [H]

Identifier: 83312996

GI number: 83312996

Start: 4307079

End: 4308809

Strand: Reverse

Name: mcpA [H]

Synonym: amb3897

Alternate gene names: 83312996

Gene position: 4308809-4307079 (Counterclockwise)

Preceding gene: 83313000

Following gene: 83312995

Centisome position: 86.75

GC content: 68.05

Gene sequence:

>1731_bases
ATGTTAGGTCTTTCGATCTGGTTCATGCGGTGGGGGCCGAACATGCTGTCGAATTGGACCGTCTCTCTGAAGATGTGGCT
GGTGGTGGGGATGATGAGCCTGCTGGCCGTGGTGATCGGCGGCGTGGGCATCACCGGCATGGAGGCCCTGGACGAACAGT
CCGGCGAGATCGAGAAGGCGGCGGCCCGCGCCATCATCGGCGAGCGCACCAACGCCCTGATCCTTTCCATCGTCATGGAT
TCGCGCGGCATCTACATGGCGCAATCGCCGGCCGAGGTGGAAAAATTCGCCACCCCCCTGCTGGAGACCATCGGGCGGTT
CGAGCGCAATATCGCCGAATGGGGCGCCATGGTGCCGCCGTCGCAGCAGGCCGACTATGCCAAGCTGAAGGAAAGCGCCG
CCCAGTTCGCCGGATTCCGCAAGGAGCTGGTCCGCATCGGACGAGCCGAGGGCGGTCCCGCCGGCCGTGAATTCGGCGAC
AACGACGTCAACCGCAAGTCCCGGCAGGAGCTCAACAAGCTGACCCAGGCGTTCGCCGACATCAACAACAAGGACATTGC
CGAGACCGCGGCCAACATGGACCGGGTGCGCAGCGCCAAGCTGCGCCTCAGCATCCTGATCACCGTGGCCGGCATCGGGC
TGATCGGCGCCATGGCCTCCCTGATCGGCAAGCGCACCATCGCCGCGCCCATCGATGCCATGGCGGCGGCCATGGACAAG
CTGCGGCAGCGCGATTACGGCGTACATATTCCCGGGGTGGGGCTGACCAACGAAATCGGCCGGATGGCCTCGTCCCTGGC
GGTGTTCCGCGACGCCATGGTGGAGACCGAGCGCCTGACCGCCGAGCATGAGGCTGAATTGACCGAGCGGGTGGAGCGCG
GCCGGGCCATGGATTCCCTGGCGCGGGATTTCGACCGCACGGTTTCGGGCGTCCTTGAGGTGGTGTCGGGGGCGGCGACC
GAGTTGCACGCCACCGCCCAGGGCATGCAGACCATCGCCGAGCAGACGCAGGACAAGGCCACGGCCGTGGCGGCGGCGGC
CGAGGAGGCCTCCAGCAGCGTCGAGACGGTGGCTACCGCCGCCGAGGAGCTGTCCGCCTCCATCGCCGAGATCGCCCGTC
AGGTGGCCCAGTCCAGCACCGCCGCCCAGCAGGCCTCGGACGAGGCCCGCCAGACCAACACCATCGTCCAGGGATTGGCG
GCCAGCTCCACCCGCATCGGCGACGTGGTCAGCCTGATCAACGACATCGCCGCCCAGACCAATCTGCTGGCGCTGAACGC
CACCATCGAGGCGGCCCGGGCGGGCGAGGCGGGCAAGGGCTTCGCCGTGGTGGCGGGCGAGGTAAAGGCCCTGGCCAACC
AGACCGGCAAGGCCACCGAGGAGATCTCGACCCAGGTCGGTGCCGTGCAGACCGCCACCCGGGAGGCGGTGGCCGCCATC
GGCAGCATCGTTGGACGGATCGAGGAGATCAACCACATCGCCACCGCCATTTCGGCGGCGGTGGAAGAGCAATCCGCCGC
CACCGCCGAAATCGCCCGCAACGTGGATCAGGCCTCCCAGGGCACGAGGCAGGTCTCGGCCAATGTGGGGGGCGTGTCGG
CCACCGCCGCCGAGACTGACGCCGCGGCGGTGCAGGTGCTGTCGGCGGCTCAGTCGTTGTCGCGCGAGGCCACCGAGCTT
AAGGACGTCGTCGACCGCTTCCTGGAAGGGGTCCGCACCGTTCAAGGCTGA

Upstream 100 bases:

>100_bases
CAGCCCTATTTCCAGACTGTTTCGGGGAGGTGGTCGCCTCAGGGTATTGCTTTGGTTTGCTGCGGGTTTCCCCCGTATGG
TCTGGCAATAAGTAAAGTGT

Downstream 100 bases:

>100_bases
CGAGCGGCGGAGCCCGGCCGGGGATGCGGTCCCGCCGGGCTTCATTTCTTGCCGGCTTCGGCAATTATAAGATGATGTTG
TCTGTAAGTAATATTGCAAG

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 576; Mature: 576

Protein sequence:

>576_residues
MLGLSIWFMRWGPNMLSNWTVSLKMWLVVGMMSLLAVVIGGVGITGMEALDEQSGEIEKAAARAIIGERTNALILSIVMD
SRGIYMAQSPAEVEKFATPLLETIGRFERNIAEWGAMVPPSQQADYAKLKESAAQFAGFRKELVRIGRAEGGPAGREFGD
NDVNRKSRQELNKLTQAFADINNKDIAETAANMDRVRSAKLRLSILITVAGIGLIGAMASLIGKRTIAAPIDAMAAAMDK
LRQRDYGVHIPGVGLTNEIGRMASSLAVFRDAMVETERLTAEHEAELTERVERGRAMDSLARDFDRTVSGVLEVVSGAAT
ELHATAQGMQTIAEQTQDKATAVAAAAEEASSSVETVATAAEELSASIAEIARQVAQSSTAAQQASDEARQTNTIVQGLA
ASSTRIGDVVSLINDIAAQTNLLALNATIEAARAGEAGKGFAVVAGEVKALANQTGKATEEISTQVGAVQTATREAVAAI
GSIVGRIEEINHIATAISAAVEEQSAATAEIARNVDQASQGTRQVSANVGGVSATAAETDAAAVQVLSAAQSLSREATEL
KDVVDRFLEGVRTVQG

Sequences:

>Translated_576_residues
MLGLSIWFMRWGPNMLSNWTVSLKMWLVVGMMSLLAVVIGGVGITGMEALDEQSGEIEKAAARAIIGERTNALILSIVMD
SRGIYMAQSPAEVEKFATPLLETIGRFERNIAEWGAMVPPSQQADYAKLKESAAQFAGFRKELVRIGRAEGGPAGREFGD
NDVNRKSRQELNKLTQAFADINNKDIAETAANMDRVRSAKLRLSILITVAGIGLIGAMASLIGKRTIAAPIDAMAAAMDK
LRQRDYGVHIPGVGLTNEIGRMASSLAVFRDAMVETERLTAEHEAELTERVERGRAMDSLARDFDRTVSGVLEVVSGAAT
ELHATAQGMQTIAEQTQDKATAVAAAAEEASSSVETVATAAEELSASIAEIARQVAQSSTAAQQASDEARQTNTIVQGLA
ASSTRIGDVVSLINDIAAQTNLLALNATIEAARAGEAGKGFAVVAGEVKALANQTGKATEEISTQVGAVQTATREAVAAI
GSIVGRIEEINHIATAISAAVEEQSAATAEIARNVDQASQGTRQVSANVGGVSATAAETDAAAVQVLSAAQSLSREATEL
KDVVDRFLEGVRTVQG
>Mature_576_residues
MLGLSIWFMRWGPNMLSNWTVSLKMWLVVGMMSLLAVVIGGVGITGMEALDEQSGEIEKAAARAIIGERTNALILSIVMD
SRGIYMAQSPAEVEKFATPLLETIGRFERNIAEWGAMVPPSQQADYAKLKESAAQFAGFRKELVRIGRAEGGPAGREFGD
NDVNRKSRQELNKLTQAFADINNKDIAETAANMDRVRSAKLRLSILITVAGIGLIGAMASLIGKRTIAAPIDAMAAAMDK
LRQRDYGVHIPGVGLTNEIGRMASSLAVFRDAMVETERLTAEHEAELTERVERGRAMDSLARDFDRTVSGVLEVVSGAAT
ELHATAQGMQTIAEQTQDKATAVAAAAEEASSSVETVATAAEELSASIAEIARQVAQSSTAAQQASDEARQTNTIVQGLA
ASSTRIGDVVSLINDIAAQTNLLALNATIEAARAGEAGKGFAVVAGEVKALANQTGKATEEISTQVGAVQTATREAVAAI
GSIVGRIEEINHIATAISAAVEEQSAATAEIARNVDQASQGTRQVSANVGGVSATAAETDAAAVQVLSAAQSLSREATEL
KDVVDRFLEGVRTVQG

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=425, Percent_Identity=27.0588235294118, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1788195, Length=198, Percent_Identity=37.3737373737374, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI1788194, Length=191, Percent_Identity=39.2670157068063, Blast_Score=105, Evalue=7e-24,
Organism=Escherichia coli, GI1789453, Length=205, Percent_Identity=36.0975609756098, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI2367378, Length=544, Percent_Identity=26.4705882352941, Blast_Score=99, Evalue=8e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 60474; Mature: 60474

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS50192 T_SNARE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGLSIWFMRWGPNMLSNWTVSLKMWLVVGMMSLLAVVIGGVGITGMEALDEQSGEIEKA
CCCCEEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHH
AARAIIGERTNALILSIVMDSRGIYMAQSPAEVEKFATPLLETIGRFERNIAEWGAMVPP
HHHHHHHCCCCCEEEEEEECCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
SQQADYAKLKESAAQFAGFRKELVRIGRAEGGPAGREFGDNDVNRKSRQELNKLTQAFAD
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHC
INNKDIAETAANMDRVRSAKLRLSILITVAGIGLIGAMASLIGKRTIAAPIDAMAAAMDK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRQRDYGVHIPGVGLTNEIGRMASSLAVFRDAMVETERLTAEHEAELTERVERGRAMDSL
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARDFDRTVSGVLEVVSGAATELHATAQGMQTIAEQTQDKATAVAAAAEEASSSVETVATA
HHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEELSASIAEIARQVAQSSTAAQQASDEARQTNTIVQGLAASSTRIGDVVSLINDIAAQT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
NLLALNATIEAARAGEAGKGFAVVAGEVKALANQTGKATEEISTQVGAVQTATREAVAAI
CEEEEECHHHHHHCCCCCCCEEEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
GSIVGRIEEINHIATAISAAVEEQSAATAEIARNVDQASQGTRQVSANVGGVSATAAETD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCHHHHH
AAAVQVLSAAQSLSREATELKDVVDRFLEGVRTVQG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLGLSIWFMRWGPNMLSNWTVSLKMWLVVGMMSLLAVVIGGVGITGMEALDEQSGEIEKA
CCCCEEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHH
AARAIIGERTNALILSIVMDSRGIYMAQSPAEVEKFATPLLETIGRFERNIAEWGAMVPP
HHHHHHHCCCCCEEEEEEECCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
SQQADYAKLKESAAQFAGFRKELVRIGRAEGGPAGREFGDNDVNRKSRQELNKLTQAFAD
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHC
INNKDIAETAANMDRVRSAKLRLSILITVAGIGLIGAMASLIGKRTIAAPIDAMAAAMDK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRQRDYGVHIPGVGLTNEIGRMASSLAVFRDAMVETERLTAEHEAELTERVERGRAMDSL
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARDFDRTVSGVLEVVSGAATELHATAQGMQTIAEQTQDKATAVAAAAEEASSSVETVATA
HHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEELSASIAEIARQVAQSSTAAQQASDEARQTNTIVQGLAASSTRIGDVVSLINDIAAQT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
NLLALNATIEAARAGEAGKGFAVVAGEVKALANQTGKATEEISTQVGAVQTATREAVAAI
CEEEEECHHHHHHCCCCCCCEEEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
GSIVGRIEEINHIATAISAAVEEQSAATAEIARNVDQASQGTRQVSANVGGVSATAAETD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCHHHHH
AAAVQVLSAAQSLSREATELKDVVDRFLEGVRTVQG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]