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The map label for this gene is nreB [H]

Identifier: 83312764

GI number: 83312764

Start: 4026337

End: 4027953

Strand: Reverse

Name: nreB [H]

Synonym: amb3665

Alternate gene names: 83312764

Gene position: 4027953-4026337 (Counterclockwise)

Preceding gene: 83312765

Following gene: 83312763

Centisome position: 81.09

GC content: 60.92

Gene sequence:

>1617_bases
ATGACCACGAGGCCCGGCTCTTCCAAAGTGGATAAATCTCAGGACGCGCATCGCGCGAAGGCCGAGGTGCAGGCTCGTCG
GAATCAGGGGGAGAGCGATCTTCTCCACGAACTCCGCGTCCACCAGATCGAGTTGGAGATGCAGAACGAGGAACTGCGTC
GGGTTCAATTGGAACTGGAAGAATCACGGGACCGATATATCGATCTCTACGAATTCGCTCCGGTCGGTTACGTGACGCTG
GGTTCATCCGGCCACATCGAATCCGCCAATCTGACTCTCTCTTCAATGCTGGGCTTCGAGCGCTCCGCCTTGCTGAAATT
GCGGTTCAGCGCCCTGGTGTCGGAGGTAAGCGGCGACGACTGGCATCGTTTCATGGCGGCCATTCTGAACGACCAGGAGG
ATCCCCATCGAACAACCGACCTCCGGCTTCGGCGTCGGGACGAGGGCACAATCGAGGCACGTCTGGATTGCCTGCGGGTC
ACGAATGCCGTCCATGGTGCGATGGTTCGGGTCGCCATAACCGACATCACCCGGATCAAGCAGACCGAAATCGCGCTGCA
AGCCAGCGAGAAGCGTTACAGCCTGCTCGCCGCGTCGACTTTCGAAGGTATTGCCATCTCCGCCAAGGGGCGCATCGTCG
ATGTGAACGAGCAACTGGTCGAAATGCTCGGCTTCCCACGAGCAGAGTTGATCGGCCGACCGGTGGCGGAGTTGATCTCC
GACGAGGATCGTGATCGCGTCATGGACAATATCCATCGCGGTCATGAAAGCCATATCGAGCACGGCATGGTCCGCAGGGA
TGGTTCCCGGATCGAGGTCGAGGCCCATGGTCAGCCATTCAGCGACGATGGGCGGGCTTTTCGTCTCACGGCGCTGCGCG
ACATCACCGCGCGGAAGGAAGACGAAGCCGCGGCTCGCATCGCCCTGCATATGGAACATCTCCGCAATCTGGCGATCGAG
GCGACGCTTTCCGAAGAGCGGGAGCGCCATTCCATCGCCAAGGACCTTCACGACGGCCTGGGACAGACGCTGCATCTGGC
CCGGTTCAAACTGGACCGGCTGGTGAAGGCTCTGCCGCAGGAGCTTCCCACCGCGACCTTGGCGCTTGAGTTGATCGGCC
TTCTCTCCGAGGCCAGTGGCGAAGTGCGCTCGCTGACCTCCAAACTCAGTCCCCCGGCGCTCAAGGACTTGGGATTGGTG
GCGGCCATATCGTGGCTGGCGGACGAAATGGGGCGGCGCCGCGGGTTGCAGGTCGTAGTGGAAGACGACGGCGTCCCGAA
ACCCCTCACCGAGGGACAGTCAACCCTTCTGTTCCGGGCTGTGCGCGAACTTGTCATCAACATCGCCAAGCACGCGGGTG
TGGGTTCTGCCCGGATTGGACTTCGTGTCTGCAATAACCGCCTGATTATCACGGTCGCGGACAAGGGCGTCGGTTTCATC
GACTGGCGAGCAACCCTTGAAGCCCGGCGTGGTTTCGGACTGTCCAGCGTGCGAGAGCGCATTACCTTCCTCAAGGGAGT
CATGGACATCCAAACTCGCCCGGGCGAGGGGACCACCGTCGTCCTGGAAATGCCGTTCGATTACAATGATTCCGCGCCCA
CGGAGATGCTGCCATGA

Upstream 100 bases:

>100_bases
TTTGGTCGGACAACCGCGGCTCCCTTCCAGCGATTCTTTGCTACCGTGTAAGAATGGCAATAGCCTAGTTTGGATCGGGC
GTGGAGCAGAGGTTCACATC

Downstream 100 bases:

>100_bases
CCATCCGCGTCATGCTGGTCGACGACCACCGCATGTTCCGAGAGGCGCTTCGGGCGCCGCTGGAAGCCGAGTCGGACATG
GAGATTGTCGCCGAAGCCAA

Product: Signal transduction histidine kinase

Products: NA

Alternate protein names: Nitrogen regulation protein B [H]

Number of amino acids: Translated: 538; Mature: 537

Protein sequence:

>538_residues
MTTRPGSSKVDKSQDAHRAKAEVQARRNQGESDLLHELRVHQIELEMQNEELRRVQLELEESRDRYIDLYEFAPVGYVTL
GSSGHIESANLTLSSMLGFERSALLKLRFSALVSEVSGDDWHRFMAAILNDQEDPHRTTDLRLRRRDEGTIEARLDCLRV
TNAVHGAMVRVAITDITRIKQTEIALQASEKRYSLLAASTFEGIAISAKGRIVDVNEQLVEMLGFPRAELIGRPVAELIS
DEDRDRVMDNIHRGHESHIEHGMVRRDGSRIEVEAHGQPFSDDGRAFRLTALRDITARKEDEAAARIALHMEHLRNLAIE
ATLSEERERHSIAKDLHDGLGQTLHLARFKLDRLVKALPQELPTATLALELIGLLSEASGEVRSLTSKLSPPALKDLGLV
AAISWLADEMGRRRGLQVVVEDDGVPKPLTEGQSTLLFRAVRELVINIAKHAGVGSARIGLRVCNNRLIITVADKGVGFI
DWRATLEARRGFGLSSVRERITFLKGVMDIQTRPGEGTTVVLEMPFDYNDSAPTEMLP

Sequences:

>Translated_538_residues
MTTRPGSSKVDKSQDAHRAKAEVQARRNQGESDLLHELRVHQIELEMQNEELRRVQLELEESRDRYIDLYEFAPVGYVTL
GSSGHIESANLTLSSMLGFERSALLKLRFSALVSEVSGDDWHRFMAAILNDQEDPHRTTDLRLRRRDEGTIEARLDCLRV
TNAVHGAMVRVAITDITRIKQTEIALQASEKRYSLLAASTFEGIAISAKGRIVDVNEQLVEMLGFPRAELIGRPVAELIS
DEDRDRVMDNIHRGHESHIEHGMVRRDGSRIEVEAHGQPFSDDGRAFRLTALRDITARKEDEAAARIALHMEHLRNLAIE
ATLSEERERHSIAKDLHDGLGQTLHLARFKLDRLVKALPQELPTATLALELIGLLSEASGEVRSLTSKLSPPALKDLGLV
AAISWLADEMGRRRGLQVVVEDDGVPKPLTEGQSTLLFRAVRELVINIAKHAGVGSARIGLRVCNNRLIITVADKGVGFI
DWRATLEARRGFGLSSVRERITFLKGVMDIQTRPGEGTTVVLEMPFDYNDSAPTEMLP
>Mature_537_residues
TTRPGSSKVDKSQDAHRAKAEVQARRNQGESDLLHELRVHQIELEMQNEELRRVQLELEESRDRYIDLYEFAPVGYVTLG
SSGHIESANLTLSSMLGFERSALLKLRFSALVSEVSGDDWHRFMAAILNDQEDPHRTTDLRLRRRDEGTIEARLDCLRVT
NAVHGAMVRVAITDITRIKQTEIALQASEKRYSLLAASTFEGIAISAKGRIVDVNEQLVEMLGFPRAELIGRPVAELISD
EDRDRVMDNIHRGHESHIEHGMVRRDGSRIEVEAHGQPFSDDGRAFRLTALRDITARKEDEAAARIALHMEHLRNLAIEA
TLSEERERHSIAKDLHDGLGQTLHLARFKLDRLVKALPQELPTATLALELIGLLSEASGEVRSLTSKLSPPALKDLGLVA
AISWLADEMGRRRGLQVVVEDDGVPKPLTEGQSTLLFRAVRELVINIAKHAGVGSARIGLRVCNNRLIITVADKGVGFID
WRATLEARRGFGLSSVRERITFLKGVMDIQTRPGEGTTVVLEMPFDYNDSAPTEMLP

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxyg

COG id: COG4564

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR011712
- InterPro:   IPR005467
- InterPro:   IPR017203 [H]

Pfam domain/function: PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 60063; Mature: 59932

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTRPGSSKVDKSQDAHRAKAEVQARRNQGESDLLHELRVHQIELEMQNEELRRVQLELE
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEEEEECHHHHHHHHHHHH
ESRDRYIDLYEFAPVGYVTLGSSGHIESANLTLSSMLGFERSALLKLRFSALVSEVSGDD
HCCCCEEEEEEECCCCEEEECCCCCCCCCCEEHHHHHCCCHHHHHHHHHHHHHHHCCCCH
WHRFMAAILNDQEDPHRTTDLRLRRRDEGTIEARLDCLRVTNAVHGAMVRVAITDITRIK
HHHHHHHHHCCCCCCCCCCCHHEEECCCCCHHHHHHHHHHHHHHHHHEEEEEHHHHHHHH
QTEIALQASEKRYSLLAASTFEGIAISAKGRIVDVNEQLVEMLGFPRAELIGRPVAELIS
HHHHHHHCCCHHHHEEEECCCCCEEEECCCCEEECHHHHHHHHCCCHHHHHCCCHHHHHC
DEDRDRVMDNIHRGHESHIEHGMVRRDGSRIEVEAHGQPFSDDGRAFRLTALRDITARKE
CCCHHHHHHHHHCCCHHHHHCCHHCCCCCEEEEEECCCCCCCCCCEEEEEHHHHHHHCCC
DEAAARIALHMEHLRNLAIEATLSEERERHSIAKDLHDGLGQTLHLARFKLDRLVKALPQ
HHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELPTATLALELIGLLSEASGEVRSLTSKLSPPALKDLGLVAAISWLADEMGRRRGLQVVV
HCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEE
EDDGVPKPLTEGQSTLLFRAVRELVINIAKHAGVGSARIGLRVCNNRLIITVADKGVGFI
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHEEECCEEEEEEECCCCEEE
DWRATLEARRGFGLSSVRERITFLKGVMDIQTRPGEGTTVVLEMPFDYNDSAPTEMLP
EHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure 
TTRPGSSKVDKSQDAHRAKAEVQARRNQGESDLLHELRVHQIELEMQNEELRRVQLELE
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEEEEECHHHHHHHHHHHH
ESRDRYIDLYEFAPVGYVTLGSSGHIESANLTLSSMLGFERSALLKLRFSALVSEVSGDD
HCCCCEEEEEEECCCCEEEECCCCCCCCCCEEHHHHHCCCHHHHHHHHHHHHHHHCCCCH
WHRFMAAILNDQEDPHRTTDLRLRRRDEGTIEARLDCLRVTNAVHGAMVRVAITDITRIK
HHHHHHHHHCCCCCCCCCCCHHEEECCCCCHHHHHHHHHHHHHHHHHEEEEEHHHHHHHH
QTEIALQASEKRYSLLAASTFEGIAISAKGRIVDVNEQLVEMLGFPRAELIGRPVAELIS
HHHHHHHCCCHHHHEEEECCCCCEEEECCCCEEECHHHHHHHHCCCHHHHHCCCHHHHHC
DEDRDRVMDNIHRGHESHIEHGMVRRDGSRIEVEAHGQPFSDDGRAFRLTALRDITARKE
CCCHHHHHHHHHCCCHHHHHCCHHCCCCCEEEEEECCCCCCCCCCEEEEEHHHHHHHCCC
DEAAARIALHMEHLRNLAIEATLSEERERHSIAKDLHDGLGQTLHLARFKLDRLVKALPQ
HHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELPTATLALELIGLLSEASGEVRSLTSKLSPPALKDLGLVAAISWLADEMGRRRGLQVVV
HCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEE
EDDGVPKPLTEGQSTLLFRAVRELVINIAKHAGVGSARIGLRVCNNRLIITVADKGVGFI
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHEEECCEEEEEEECCCCEEE
DWRATLEARRGFGLSSVRERITFLKGVMDIQTRPGEGTTVVLEMPFDYNDSAPTEMLP
EHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA