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The map label for this gene is mcpA [H]

Identifier: 83312566

GI number: 83312566

Start: 3807462

End: 3809144

Strand: Reverse

Name: mcpA [H]

Synonym: amb3467

Alternate gene names: 83312566

Gene position: 3809144-3807462 (Counterclockwise)

Preceding gene: 83312567

Following gene: 83312565

Centisome position: 76.69

GC content: 69.46

Gene sequence:

>1683_bases
ATGGCCGGTCGGTTGCGCATCGGGGTCAAGATCCAGCTTCTGGTGGGCGTCATGGCCGTGGTGGCGGTGGTGATCGCCGC
CCTGGGCCAGTGGGCCATCAGCAGCTATGATTCCCGGACCGATGCCATCCTCGACGCGTCGCGCCGGGCCGCCTTCGGGC
AGAAGGCCGGAAGCGCCATCTACGCCATCGTCATGGATTCGCGCGGCGTCTACATGGCGCGCAACGCCGACGAGGTGCGG
AAATTCGCCGAGCCCATGGCCAAGAGCCTCGACGCCTTCGAGAAAATGGCCGCTGAGTGGCGGGGCGTGGTGCCCGCGGA
GCAGACTGCCGAGTTCGCCAAGCTGAACAAGGAACTGGTCGACTTCATCCGCTTTCGCCGCGAACTGATCCGTCTCGGCC
TGGAACAGGGGGCACCGGCGGCCCGGGTGTTCGGCGACAATGATGCCAACCGCTCGAACCGGCAGAAGCTGGGCAAGCTG
GTGGACGAGTATTCCGCCATGGCCGACCGCGAGGTTGACGAAAACCACCTGGCCATGGACGCCTTCGCCGGCCAACTGAA
GATCGGCCTGCTGTTGGGCGCCCTGACCGCGCTGCTGGGCGGCGGGATCGTCACCCTGATCATGGTCCGCCGGTCGGTGT
CGGGACCGCTGGGCCGGGTGGCGGCGGCCACCCACCGCATGGCGGCGGGCTATCTCGACGAGCCGGTGGCCGATGCCGAA
CGCGGCGATGAAGCCGGCGAGATCGCCAGGGCGCTGCAGGTGTTCCGCGACACCATGCGCCGCACCCGCGAACTGGAAGC
GGCCGCCCTGGCCGAGCAGCGCCGCCGCGCCGAACGGGCGGAATATCTGGAACGGCGGACCGCCGAATTCGATCGCACCG
TCCAGTCGCTGCTGGGCGACGTGGGCGAGGTGGTGCGCACCGTCTCCACCACCGCCGATAATCTTCACCGCAACGTGGAC
GATGCCGGGCATGAAAGCGCCTCGGTGGCGGTGGCCGCCGCCCAATCCTGCGCCAATGTGCAGGAAGTGGCCTCGGCCAC
CGGGCAATTGCGCTCGTCGAGCATGGGCATCGCCGAACGCGTCCGCGAGACCACCGCCATCGTGCGCGAGACCGTGGACG
TCATGGAGGGGGCCGGGGCCACCATGGCCTCCCTGGACGACGGGGCCAAGCGCATCGGCGAGGTGGTCAGCCTGATCAAC
GACATCGCCGCCCAGACCAATCTGCTGGCGTTGAACGCCACCATCGAGGCGGCGCGGGCCGGCGAGGCGGGCAAGGGCTT
TGCCGTGGTGGCGGGCGAGGTCAAGAATCTCGCCAACCAGACGGCGCGGGCCACCGACGAGATCGGCCGGCAGGTCGCCG
CCATGCAGGACACGGTCGCCCAGGTGGTCGCCACCAATCATCGGGTGGCCGAATCCATCGGCCGCATTGAATCCGTGGCC
GGAGCGGTGGCCTCGGCGGCGGTGGAGCAGGGGCACGTCACCGACGCCATCGTGCAGAACGTGCAGGAAGCGGCCCAGGG
CGGCCGCTCGGTCACCGACAGCATCTCGAAGGTGTCCCGCCAGGTGGAGGCGGGAGGCGCCATGGCCGGAGACCTGGCCC
ACATGGCCCATTCCCTGGCGGACCGGGCCCAGTCGCTGCGGGCGGCGGTCACCGGCTTCCTGGTGGACGCCAAGACCGTC
TGA

Upstream 100 bases:

>100_bases
AAATATGTTGACTTCCCGCCCGGTCCATTGCCACTCTTGGCCGTATCGCGAAGCAGGGTAGCTGCCTTACCGTGTGCCGC
GCATTGAGATGGAGGAAGCC

Downstream 100 bases:

>100_bases
CAGCGGTTCGACACGGGCGTTCTTGCCGCTATACTCCCCGGGACCAATGGGGAGTGATCGCGTGCACGGGTCCGAAGCGC
TGTTCGATGTCTTGTCGCTG

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 560; Mature: 559

Protein sequence:

>560_residues
MAGRLRIGVKIQLLVGVMAVVAVVIAALGQWAISSYDSRTDAILDASRRAAFGQKAGSAIYAIVMDSRGVYMARNADEVR
KFAEPMAKSLDAFEKMAAEWRGVVPAEQTAEFAKLNKELVDFIRFRRELIRLGLEQGAPAARVFGDNDANRSNRQKLGKL
VDEYSAMADREVDENHLAMDAFAGQLKIGLLLGALTALLGGGIVTLIMVRRSVSGPLGRVAAATHRMAAGYLDEPVADAE
RGDEAGEIARALQVFRDTMRRTRELEAAALAEQRRRAERAEYLERRTAEFDRTVQSLLGDVGEVVRTVSTTADNLHRNVD
DAGHESASVAVAAAQSCANVQEVASATGQLRSSSMGIAERVRETTAIVRETVDVMEGAGATMASLDDGAKRIGEVVSLIN
DIAAQTNLLALNATIEAARAGEAGKGFAVVAGEVKNLANQTARATDEIGRQVAAMQDTVAQVVATNHRVAESIGRIESVA
GAVASAAVEQGHVTDAIVQNVQEAAQGGRSVTDSISKVSRQVEAGGAMAGDLAHMAHSLADRAQSLRAAVTGFLVDAKTV

Sequences:

>Translated_560_residues
MAGRLRIGVKIQLLVGVMAVVAVVIAALGQWAISSYDSRTDAILDASRRAAFGQKAGSAIYAIVMDSRGVYMARNADEVR
KFAEPMAKSLDAFEKMAAEWRGVVPAEQTAEFAKLNKELVDFIRFRRELIRLGLEQGAPAARVFGDNDANRSNRQKLGKL
VDEYSAMADREVDENHLAMDAFAGQLKIGLLLGALTALLGGGIVTLIMVRRSVSGPLGRVAAATHRMAAGYLDEPVADAE
RGDEAGEIARALQVFRDTMRRTRELEAAALAEQRRRAERAEYLERRTAEFDRTVQSLLGDVGEVVRTVSTTADNLHRNVD
DAGHESASVAVAAAQSCANVQEVASATGQLRSSSMGIAERVRETTAIVRETVDVMEGAGATMASLDDGAKRIGEVVSLIN
DIAAQTNLLALNATIEAARAGEAGKGFAVVAGEVKNLANQTARATDEIGRQVAAMQDTVAQVVATNHRVAESIGRIESVA
GAVASAAVEQGHVTDAIVQNVQEAAQGGRSVTDSISKVSRQVEAGGAMAGDLAHMAHSLADRAQSLRAAVTGFLVDAKTV
>Mature_559_residues
AGRLRIGVKIQLLVGVMAVVAVVIAALGQWAISSYDSRTDAILDASRRAAFGQKAGSAIYAIVMDSRGVYMARNADEVRK
FAEPMAKSLDAFEKMAAEWRGVVPAEQTAEFAKLNKELVDFIRFRRELIRLGLEQGAPAARVFGDNDANRSNRQKLGKLV
DEYSAMADREVDENHLAMDAFAGQLKIGLLLGALTALLGGGIVTLIMVRRSVSGPLGRVAAATHRMAAGYLDEPVADAER
GDEAGEIARALQVFRDTMRRTRELEAAALAEQRRRAERAEYLERRTAEFDRTVQSLLGDVGEVVRTVSTTADNLHRNVDD
AGHESASVAVAAAQSCANVQEVASATGQLRSSSMGIAERVRETTAIVRETVDVMEGAGATMASLDDGAKRIGEVVSLIND
IAAQTNLLALNATIEAARAGEAGKGFAVVAGEVKNLANQTARATDEIGRQVAAMQDTVAQVVATNHRVAESIGRIESVAG
AVASAAVEQGHVTDAIVQNVQEAAQGGRSVTDSISKVSRQVEAGGAMAGDLAHMAHSLADRAQSLRAAVTGFLVDAKTV

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=308, Percent_Identity=29.5454545454545, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1789453, Length=260, Percent_Identity=30.7692307692308, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1787690, Length=381, Percent_Identity=25.4593175853018, Blast_Score=99, Evalue=9e-22,
Organism=Escherichia coli, GI2367378, Length=327, Percent_Identity=25.6880733944954, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1788194, Length=369, Percent_Identity=25.4742547425474, Blast_Score=92, Evalue=9e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 59241; Mature: 59110

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGRLRIGVKIQLLVGVMAVVAVVIAALGQWAISSYDSRTDAILDASRRAAFGQKAGSAI
CCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEE
YAIVMDSRGVYMARNADEVRKFAEPMAKSLDAFEKMAAEWRGVVPAEQTAEFAKLNKELV
EEEEECCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
DFIRFRRELIRLGLEQGAPAARVFGDNDANRSNRQKLGKLVDEYSAMADREVDENHLAMD
HHHHHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
AFAGQLKIGLLLGALTALLGGGIVTLIMVRRSVSGPLGRVAAATHRMAAGYLDEPVADAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHH
RGDEAGEIARALQVFRDTMRRTRELEAAALAEQRRRAERAEYLERRTAEFDRTVQSLLGD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGEVVRTVSTTADNLHRNVDDAGHESASVAVAAAQSCANVQEVASATGQLRSSSMGIAER
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
VRETTAIVRETVDVMEGAGATMASLDDGAKRIGEVVSLINDIAAQTNLLALNATIEAARA
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEHHHHHHHC
GEAGKGFAVVAGEVKNLANQTARATDEIGRQVAAMQDTVAQVVATNHRVAESIGRIESVA
CCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAVASAAVEQGHVTDAIVQNVQEAAQGGRSVTDSISKVSRQVEAGGAMAGDLAHMAHSLA
HHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
DRAQSLRAAVTGFLVDAKTV
HHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AGRLRIGVKIQLLVGVMAVVAVVIAALGQWAISSYDSRTDAILDASRRAAFGQKAGSAI
CCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEE
YAIVMDSRGVYMARNADEVRKFAEPMAKSLDAFEKMAAEWRGVVPAEQTAEFAKLNKELV
EEEEECCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
DFIRFRRELIRLGLEQGAPAARVFGDNDANRSNRQKLGKLVDEYSAMADREVDENHLAMD
HHHHHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
AFAGQLKIGLLLGALTALLGGGIVTLIMVRRSVSGPLGRVAAATHRMAAGYLDEPVADAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHH
RGDEAGEIARALQVFRDTMRRTRELEAAALAEQRRRAERAEYLERRTAEFDRTVQSLLGD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGEVVRTVSTTADNLHRNVDDAGHESASVAVAAAQSCANVQEVASATGQLRSSSMGIAER
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
VRETTAIVRETVDVMEGAGATMASLDDGAKRIGEVVSLINDIAAQTNLLALNATIEAARA
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEHHHHHHHC
GEAGKGFAVVAGEVKNLANQTARATDEIGRQVAAMQDTVAQVVATNHRVAESIGRIESVA
CCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAVASAAVEQGHVTDAIVQNVQEAAQGGRSVTDSISKVSRQVEAGGAMAGDLAHMAHSLA
HHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
DRAQSLRAAVTGFLVDAKTV
HHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]