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The map label for this gene is aphA [H]

Identifier: 83312486

GI number: 83312486

Start: 3680656

End: 3682101

Strand: Reverse

Name: aphA [H]

Synonym: amb3387

Alternate gene names: 83312486

Gene position: 3682101-3680656 (Counterclockwise)

Preceding gene: 83312490

Following gene: 83312483

Centisome position: 74.13

GC content: 65.28

Gene sequence:

>1446_bases
GTGGTGCCAGGGGCGTCGGCAGAAAGTGAAATTGTGCGTGCCGGGGGGCATGGGAGCGGCGTCTTCCGGGATTCCGTGGT
ACGGCTGCTGCTGCCTTTGCCGCTGAACCTGCTGTTTTTTGGCGGGACCGCCTTTGCCGTGCTGGTAGCCGAACTGGTTG
CCGCCCTGGTCAGCCTAGCCATGGTCGGCCATGTGCCGCCGGTGGTCTGGGCGGGGGCTTTCTTCGCGCCGCTGGTGGTG
GCGCCCGCCGAACTGGCGGTGCTGGTGGCGGTGATCGGCCGCATGCGCGATGAAATGGACCGCCGGCGTCAGGCGGAACA
GCACCTCTTGGAGGATATGGCGGGTCGCCGCGAGGTGGAGGCCGAGCTGCGTTCCAACGAGGAGAAGCTGCGGGCCATGT
TCGAGAAGTCTCCGCTGGGCATGGCGCGCAATCGTGTCGACGGCAGTTTTCTCGAGGCCAATCCGGCCTTTCTCGGGATC
GTTGGCTACGATATTGAGGATTTGCGCAGCCTGAGTTACTGGGACCTCACCCCGGTGCGTTTCGGCCAGGACGAGGCCAC
CCAGCTGGAGCGCCTGGAGGCCCTGGGGCATTACGGGCCCTACGAGAAGGAATACATCCGCAAGGACGGCCGACGGGTTC
CCGTCCGGCTGTCGGGGATGTTGGCCACCGGCCGCGACGGGGAAAGCTATATCTGGTCCATCGTCGAGGACATCACCGAA
TCCCAGGCGGTCGAGCGGGCCTTGATGGCCAAGACCGAGGAACTGGCCCGGTCCAATGCCGACCTGGAGCAATTCGCCTT
CATCGCGTCCCATGACCTGCGCGAGCCATTGCGCATGGTCAGCGCCTATATGGGCATGCTGGAGCGCCGCTTCGGCCCCG
TGGTCGGCGACGAGGGGGCCGAGTACATCGCCTATGCCAAGGAAGGCGCCCAGCGCATGGATCAGCTTGTGCTGGACCTG
CTGGAATACTCGCGGGTCGGCCGGATGGAGGAGCCGCTGGAGCCGGTTCCCCTGGGCGAGGTGGTGGATGGCGTCGTGGC
CAATCTGTCACCGGCCATCGCCCAATACGGCGCCAGCGTGGAATGCCGGTCTCCGTTACCGGCCATTCCCGCCGTGCGTG
GCGAGATGGCGCAGTTGCTCCAGAACCTGATCGGCAATGCGGTGAAATATCGCGAGCCGTCCCGGCCCCTGCGGGTGGTG
GTATCGGCGGTTCGCGACGGCGAGTACTGGCAAATCTCGGTGGCCGATAACGGCATCGGCATCTCGCCGGAGTTCTCCGA
GCGGATATTCCGCATCTTTCAGCGGCTGCACACCCGTGACTGCTTTGAAGGAACCGGCATCGGACTGGCCATCTGCAAGC
GCATCGTCGAGCGCCACGGCGGCCGGATCTGGGTGAATTCGGTGCCCGGCGAAGGATCCACCTTCACCTTCACCCTGCCG
GAGTAA

Upstream 100 bases:

>100_bases
GGATAGGCCATAACTTAAGTGTTGATACGGGTTTAACCTGACCATACTCTATGAATGGACATAAATCGCTACATTTTGTT
TCTTGTTCATCGGGGTTTGG

Downstream 100 bases:

>100_bases
CCGGCAGGGCTTGGGGCGACGGCCTATTTCTTGCCCTTGCCCTTGGGGGCGGGGGGAGACATTTCTCCGCCCAGGGTCTG
CCATAGCTGAGTGACGATCT

Product: sensor protein fixL

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 481; Mature: 481

Protein sequence:

>481_residues
MVPGASAESEIVRAGGHGSGVFRDSVVRLLLPLPLNLLFFGGTAFAVLVAELVAALVSLAMVGHVPPVVWAGAFFAPLVV
APAELAVLVAVIGRMRDEMDRRRQAEQHLLEDMAGRREVEAELRSNEEKLRAMFEKSPLGMARNRVDGSFLEANPAFLGI
VGYDIEDLRSLSYWDLTPVRFGQDEATQLERLEALGHYGPYEKEYIRKDGRRVPVRLSGMLATGRDGESYIWSIVEDITE
SQAVERALMAKTEELARSNADLEQFAFIASHDLREPLRMVSAYMGMLERRFGPVVGDEGAEYIAYAKEGAQRMDQLVLDL
LEYSRVGRMEEPLEPVPLGEVVDGVVANLSPAIAQYGASVECRSPLPAIPAVRGEMAQLLQNLIGNAVKYREPSRPLRVV
VSAVRDGEYWQISVADNGIGISPEFSERIFRIFQRLHTRDCFEGTGIGLAICKRIVERHGGRIWVNSVPGEGSTFTFTLP
E

Sequences:

>Translated_481_residues
MVPGASAESEIVRAGGHGSGVFRDSVVRLLLPLPLNLLFFGGTAFAVLVAELVAALVSLAMVGHVPPVVWAGAFFAPLVV
APAELAVLVAVIGRMRDEMDRRRQAEQHLLEDMAGRREVEAELRSNEEKLRAMFEKSPLGMARNRVDGSFLEANPAFLGI
VGYDIEDLRSLSYWDLTPVRFGQDEATQLERLEALGHYGPYEKEYIRKDGRRVPVRLSGMLATGRDGESYIWSIVEDITE
SQAVERALMAKTEELARSNADLEQFAFIASHDLREPLRMVSAYMGMLERRFGPVVGDEGAEYIAYAKEGAQRMDQLVLDL
LEYSRVGRMEEPLEPVPLGEVVDGVVANLSPAIAQYGASVECRSPLPAIPAVRGEMAQLLQNLIGNAVKYREPSRPLRVV
VSAVRDGEYWQISVADNGIGISPEFSERIFRIFQRLHTRDCFEGTGIGLAICKRIVERHGGRIWVNSVPGEGSTFTFTLP
E
>Mature_481_residues
MVPGASAESEIVRAGGHGSGVFRDSVVRLLLPLPLNLLFFGGTAFAVLVAELVAALVSLAMVGHVPPVVWAGAFFAPLVV
APAELAVLVAVIGRMRDEMDRRRQAEQHLLEDMAGRREVEAELRSNEEKLRAMFEKSPLGMARNRVDGSFLEANPAFLGI
VGYDIEDLRSLSYWDLTPVRFGQDEATQLERLEALGHYGPYEKEYIRKDGRRVPVRLSGMLATGRDGESYIWSIVEDITE
SQAVERALMAKTEELARSNADLEQFAFIASHDLREPLRMVSAYMGMLERRFGPVVGDEGAEYIAYAKEGAQRMDQLVLDL
LEYSRVGRMEEPLEPVPLGEVVDGVVANLSPAIAQYGASVECRSPLPAIPAVRGEMAQLLQNLIGNAVKYREPSRPLRVV
VSAVRDGEYWQISVADNGIGISPEFSERIFRIFQRLHTRDCFEGTGIGLAICKRIVERHGGRIWVNSVPGEGSTFTFTLP
E

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=264, Percent_Identity=27.2727272727273, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1786912, Length=250, Percent_Identity=32.4, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI48994928, Length=411, Percent_Identity=27.2506082725061, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1788713, Length=267, Percent_Identity=26.2172284644195, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788549, Length=249, Percent_Identity=29.3172690763052, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1786600, Length=221, Percent_Identity=28.9592760180996, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789149, Length=251, Percent_Identity=29.4820717131474, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1790436, Length=217, Percent_Identity=31.7972350230415, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1790346, Length=216, Percent_Identity=31.0185185185185, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI87081816, Length=235, Percent_Identity=28.5106382978723, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1788393, Length=253, Percent_Identity=27.2727272727273, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1789808, Length=201, Percent_Identity=29.3532338308458, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 53113; Mature: 53113

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVPGASAESEIVRAGGHGSGVFRDSVVRLLLPLPLNLLFFGGTAFAVLVAELVAALVSLA
CCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MVGHVPPVVWAGAFFAPLVVAPAELAVLVAVIGRMRDEMDRRRQAEQHLLEDMAGRREVE
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
AELRSNEEKLRAMFEKSPLGMARNRVDGSFLEANPAFLGIVGYDIEDLRSLSYWDLTPVR
HHHHCCHHHHHHHHHHCCCHHHHHCCCCCEEECCCCEEEEECCCHHHHHCCCCCCCCCCC
FGQDEATQLERLEALGHYGPYEKEYIRKDGRRVPVRLSGMLATGRDGESYIWSIVEDITE
CCCHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCEEEECEEECCCCCHHHHHHHHHHHHH
SQAVERALMAKTEELARSNADLEQFAFIASHDLREPLRMVSAYMGMLERRFGPVVGDEGA
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
EYIAYAKEGAQRMDQLVLDLLEYSRVGRMEEPLEPVPLGEVVDGVVANLSPAIAQYGASV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHCCCC
ECRSPLPAIPAVRGEMAQLLQNLIGNAVKYREPSRPLRVVVSAVRDGEYWQISVADNGIG
CCCCCCCCCCHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHCCCCEEEEEEECCCCC
ISPEFSERIFRIFQRLHTRDCFEGTGIGLAICKRIVERHGGRIWVNSVPGEGSTFTFTLP
CCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCEEEEECC
E
C
>Mature Secondary Structure
MVPGASAESEIVRAGGHGSGVFRDSVVRLLLPLPLNLLFFGGTAFAVLVAELVAALVSLA
CCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MVGHVPPVVWAGAFFAPLVVAPAELAVLVAVIGRMRDEMDRRRQAEQHLLEDMAGRREVE
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
AELRSNEEKLRAMFEKSPLGMARNRVDGSFLEANPAFLGIVGYDIEDLRSLSYWDLTPVR
HHHHCCHHHHHHHHHHCCCHHHHHCCCCCEEECCCCEEEEECCCHHHHHCCCCCCCCCCC
FGQDEATQLERLEALGHYGPYEKEYIRKDGRRVPVRLSGMLATGRDGESYIWSIVEDITE
CCCHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCEEEECEEECCCCCHHHHHHHHHHHHH
SQAVERALMAKTEELARSNADLEQFAFIASHDLREPLRMVSAYMGMLERRFGPVVGDEGA
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
EYIAYAKEGAQRMDQLVLDLLEYSRVGRMEEPLEPVPLGEVVDGVVANLSPAIAQYGASV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHCCCC
ECRSPLPAIPAVRGEMAQLLQNLIGNAVKYREPSRPLRVVVSAVRDGEYWQISVADNGIG
CCCCCCCCCCHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHCCCCEEEEEEECCCCC
ISPEFSERIFRIFQRLHTRDCFEGTGIGLAICKRIVERHGGRIWVNSVPGEGSTFTFTLP
CCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCEEEEECC
E
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]