Click here to switch to the map view.

The map label for this gene is etfA [H]

Identifier: 83312328

GI number: 83312328

Start: 3489850

End: 3490788

Strand: Reverse

Name: etfA [H]

Synonym: amb3229

Alternate gene names: 83312328

Gene position: 3490788-3489850 (Counterclockwise)

Preceding gene: 83312329

Following gene: 83312325

Centisome position: 70.28

GC content: 68.69

Gene sequence:

>939_bases
ATGACCATTCTGGTTATCGCGGAACATGAAGGCGGCGCTCTCAAATCCGCCACGCTGAACACCGTTTCCGCCGCTTCCAA
GATCGGCGGCGACGTGCATGTGCTGGTGGCCGGCTCGGGCATCGGCGCGGTGGCCGAGGCCGCCGCCAAGGTGGCGGGCG
TCGCCAAGGTGCTGTCGGCCGACGCCGCCCTTTACGCCAACCATCTGGCCGAGCCGCTGGCCGCCCTGGTGGTGAGTCTT
GCCGGGTCCTATTCCCACATCCTGGCCCCGGCCACCACGGGGGGCAAGAACGTGGCGCCCCGCGTCGCCGCCCTGCTGGA
CGTGGCGCAGATCTCCGAGATCACCGCCGTGGTGTCGCCCGATACCTTCGTGCGGCCGATCTATGCCGGCAACGCCCTGG
CCACCGTGCAGTCCAAGGACGCGGTCAAGGTGATCACCGTGCGCGGCACCGGCTTCGAGGCCGCCAAGGCCGAGGGCGGC
TCCGCCGCCGTGGAAGCCGTGTCGGCCGCCGCCGATCCGGCCCTGTCGTCCTTCGTCGGCAGCCAGCTGTCCAAGTCCGA
GCGTCCGGAACTGACCTCGGCCCGGATCATCATCTCGGGCGGTCGCGGCATGCAGTCGGGCGACAACTTCCACCTGCTGG
AAGCCGTGGCCGACAAGCTGGGCGCCGCAGTCGGTGCCTCGCGCGCCGCCGTGGACGCCGGCTTCGTGCCCAACGACTTC
CAGGTGGGCCAGACCGGCAAGATCGTCGCGCCCGACCTCTACATCGCCGTCGGCATCTCGGGCGCCATCCAGCACCTGGC
CGGCATGAAGGATTCCAAGGTCATCGTCGCCATCAACAAGGACGAAGAGGCCCCCATCTTCCAGGTCGCCGATTACGGCC
TGGTCGCGGATCTCTTCAAGGTGTTGCCGGAATTCACCGCGGCCCTCCAGTCTCCCTGA

Upstream 100 bases:

>100_bases
TGCCCCAAACCCCCCTTGAATTCAAAAGGGGTCCGGGGTCTTCCCCGGTCGGGGTGCGGGGCGGAAGCCCCGACGTGGCC
AGGACAAGGAACGAAAAGAC

Downstream 100 bases:

>100_bases
GGCCGCTGACTGGCGGGGGCGGGCCCGGCACAGGCCCGCCCCCGCATTTTCTTGACGTATCCCGAATCGCCGGCGTTCAG
GCCAGCAATCGCGCTCCCAT

Product: electron transfer flavoprotein

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MTILVIAEHEGGALKSATLNTVSAASKIGGDVHVLVAGSGIGAVAEAAAKVAGVAKVLSADAALYANHLAEPLAALVVSL
AGSYSHILAPATTGGKNVAPRVAALLDVAQISEITAVVSPDTFVRPIYAGNALATVQSKDAVKVITVRGTGFEAAKAEGG
SAAVEAVSAAADPALSSFVGSQLSKSERPELTSARIIISGGRGMQSGDNFHLLEAVADKLGAAVGASRAAVDAGFVPNDF
QVGQTGKIVAPDLYIAVGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGLVADLFKVLPEFTAALQSP

Sequences:

>Translated_312_residues
MTILVIAEHEGGALKSATLNTVSAASKIGGDVHVLVAGSGIGAVAEAAAKVAGVAKVLSADAALYANHLAEPLAALVVSL
AGSYSHILAPATTGGKNVAPRVAALLDVAQISEITAVVSPDTFVRPIYAGNALATVQSKDAVKVITVRGTGFEAAKAEGG
SAAVEAVSAAADPALSSFVGSQLSKSERPELTSARIIISGGRGMQSGDNFHLLEAVADKLGAAVGASRAAVDAGFVPNDF
QVGQTGKIVAPDLYIAVGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGLVADLFKVLPEFTAALQSP
>Mature_311_residues
TILVIAEHEGGALKSATLNTVSAASKIGGDVHVLVAGSGIGAVAEAAAKVAGVAKVLSADAALYANHLAEPLAALVVSLA
GSYSHILAPATTGGKNVAPRVAALLDVAQISEITAVVSPDTFVRPIYAGNALATVQSKDAVKVITVRGTGFEAAKAEGGS
AAVEAVSAAADPALSSFVGSQLSKSERPELTSARIIISGGRGMQSGDNFHLLEAVADKLGAAVGASRAAVDAGFVPNDFQ
VGQTGKIVAPDLYIAVGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGLVADLFKVLPEFTAALQSP

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=311, Percent_Identity=61.4147909967846, Blast_Score=373, Evalue=1e-104,
Organism=Homo sapiens, GI189181759, Length=271, Percent_Identity=63.4686346863469, Blast_Score=335, Evalue=3e-92,
Organism=Escherichia coli, GI1786226, Length=228, Percent_Identity=34.6491228070175, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1787990, Length=255, Percent_Identity=32.156862745098, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI87082157, Length=221, Percent_Identity=35.7466063348416, Blast_Score=91, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17506929, Length=311, Percent_Identity=59.4855305466238, Blast_Score=343, Evalue=5e-95,
Organism=Saccharomyces cerevisiae, GI6325261, Length=317, Percent_Identity=43.217665615142, Blast_Score=250, Evalue=2e-67,
Organism=Drosophila melanogaster, GI17136898, Length=312, Percent_Identity=65.3846153846154, Blast_Score=375, Evalue=1e-104,
Organism=Drosophila melanogaster, GI24652801, Length=312, Percent_Identity=65.3846153846154, Blast_Score=375, Evalue=1e-104,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 31242; Mature: 31111

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTILVIAEHEGGALKSATLNTVSAASKIGGDVHVLVAGSGIGAVAEAAAKVAGVAKVLSA
CEEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHH
DAALYANHLAEPLAALVVSLAGSYSHILAPATTGGKNVAPRVAALLDVAQISEITAVVSP
HHHHHHHHHHHHHHHHHHHHCCCCHHEEEECCCCCCCHHHHHHHHHHHHHHHHHHEEECC
DTFVRPIYAGNALATVQSKDAVKVITVRGTGFEAAKAEGGSAAVEAVSAAADPALSSFVG
CHHCCEEECCCEEEEEECCCCEEEEEEECCCCCHHCCCCCHHHHHHHHHHCCHHHHHHHH
SQLSKSERPELTSARIIISGGRGMQSGDNFHLLEAVADKLGAAVGASRAAVDAGFVPNDF
HHHCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHCCCCCCCCC
QVGQTGKIVAPDLYIAVGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGLVADLFK
EECCCCCEECCCEEEEECHHHHHHHHHCCCCCEEEEEECCCCCCCEEEECCHHHHHHHHH
VLPEFTAALQSP
HHHHHHHHHCCC
>Mature Secondary Structure 
TILVIAEHEGGALKSATLNTVSAASKIGGDVHVLVAGSGIGAVAEAAAKVAGVAKVLSA
EEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHH
DAALYANHLAEPLAALVVSLAGSYSHILAPATTGGKNVAPRVAALLDVAQISEITAVVSP
HHHHHHHHHHHHHHHHHHHHCCCCHHEEEECCCCCCCHHHHHHHHHHHHHHHHHHEEECC
DTFVRPIYAGNALATVQSKDAVKVITVRGTGFEAAKAEGGSAAVEAVSAAADPALSSFVG
CHHCCEEECCCEEEEEECCCCEEEEEEECCCCCHHCCCCCHHHHHHHHHHCCHHHHHHHH
SQLSKSERPELTSARIIISGGRGMQSGDNFHLLEAVADKLGAAVGASRAAVDAGFVPNDF
HHHCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHCCCCCCCCC
QVGQTGKIVAPDLYIAVGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGLVADLFK
EECCCCCEECCCEEEEECHHHHHHHHHCCCCCEEEEEECCCCCCCEEEECCHHHHHHHHH
VLPEFTAALQSP
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]