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The map label for this gene is aer [C]

Identifier: 83312291

GI number: 83312291

Start: 3458083

End: 3459516

Strand: Reverse

Name: aer [C]

Synonym: amb3192

Alternate gene names: 83312291

Gene position: 3459516-3458083 (Counterclockwise)

Preceding gene: 83312292

Following gene: 83312290

Centisome position: 69.65

GC content: 67.85

Gene sequence:

>1434_bases
GTGTGGACATTAGGGGTAGGCACCCAGGGGGATGTAATGGCTTGGATTTTCGGTGGAAAGACGGCTGCCAAGGCCGATCT
GCGGCCCATGGACGTGGCCAATGACCAGGCGCTGTCGTCGCTTCAGTCCGAGTCCATCGGGGCGGCCCTGGATCAGCTTC
TGGCTGGCAAGTATCACTCCGTTCCCGCCGGCACCTGCCCCGTTACCGCCAAGATCAAGGCCCTGGCCGACCGGCTGGAA
TCCCAGGCGCAAGCCAATCTGAGGCTGGACGTCGGTCTTTCGGTCAACGTCAACGAGGCGGTGACCAAGGCCGCCGGCAT
GATGCGCGACGTGGGCGAGGTGGATCGTCGCGCCCAGGCCATTGCCGTGGCCGCCGAACAGCTGGTGTCGAGCGTGGCCG
AGATCGCCAGGACCTCCAAGGCCGCCGCCGAGGATGCCGGCGCCGCCGAGAGCGTCGCCCAGGAAAGCCACGGCGCCGCC
GATCAGGCCATCGGCGCCATGCAGGCCATCGCCGAGGCGGTGCAGGCCGCCGCCGGCAAGGTGGATTCCCTGGCCGAGGC
CTCGGTGCAGATCGGCGACATCGTCAATCAGATCGAGGACATCGCGTCGCAGACCAACCTGCTGGCCCTGAACGCCACCA
TCGAGGCGGCGCGGGCGGGCGAGGCGGGCAAGGGCTTTGCGGTCGTCGCCAACGAGGTGAAGAACCTGGCCAACCAGACG
GCGCGCGCCACCGTGGACATCCGGGCCCGCATTGAATCCCTGCGGGTCGAGATGGGCGAGATCGTCCGCACCATGCAGGA
CGGCGCCGGCGCCGTCGAGCACGGCAAGGAGGTCATCAGCGCCACCAGTGACGGCATGGGCCGCCTGTCCACCCAGGTCC
AGGGCGTCTCGGTCAAGATGGCCCAGATCGCCGGCATTTTGAACCAGCAGAGCGCCGCTTCGGCCGAGGTGGCCGAGGGC
GTCGGCGCCATCGCCGGCCTGTCGGCCCGCAATGTCGCCACCATCAACGACGTGGTCGAGGAGATGGACGGCGCCTCCAA
GGGCATCGTCGCCGCCCTGAACGAGATGGCGGCGCTGGAGATCGACGACTTCACCCTGCATGTGGCCAAGTCCGACCACA
TGCTGTGGCGCAAGCGCCTTGCCGACATGGTGGTCGGGCGCGAGGTGCTCAATCCCGACGATCTGGCCGATCACACCAAA
TGCCGCCTGGGCAAGTGGTGCTCGACCCTCACGGATGAGAGTATCTTGCGCCATCCGGCCTACGCCGCCCTTGAAGCGCC
CCACCGCGAGGTGCACCGGAACGGCATCGATGCCGCCCGCTGCTTCAAGAATGGCGACCTGGACGGGGCGCTGGCCGCCA
TCGCCCGCGCCGCCGAGGCCTCGGTGGGGGTGATGAAGTGCCTGGACGATCTTGGTGACCGTCGGCGCTTTTAG

Upstream 100 bases:

>100_bases
CGTGTCTGGACGAAGCCGCACGCAGCATTTGGTAGGTTGAAACATATCTGTAATACAAATGGTATATTCCGCCCTGCTGC
ATTAGGGGCTTATACATAGG

Downstream 100 bases:

>100_bases
AGCGCCATTCCCCGGATTCCGTTTGCCCCTGGGGGCCAAACGCGATACATCGGGCATTGCCAGATAACCGAGCGGTCGTC
ATTGCGACGCCCGCCCTTGT

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 477; Mature: 477

Protein sequence:

>477_residues
MWTLGVGTQGDVMAWIFGGKTAAKADLRPMDVANDQALSSLQSESIGAALDQLLAGKYHSVPAGTCPVTAKIKALADRLE
SQAQANLRLDVGLSVNVNEAVTKAAGMMRDVGEVDRRAQAIAVAAEQLVSSVAEIARTSKAAAEDAGAAESVAQESHGAA
DQAIGAMQAIAEAVQAAAGKVDSLAEASVQIGDIVNQIEDIASQTNLLALNATIEAARAGEAGKGFAVVANEVKNLANQT
ARATVDIRARIESLRVEMGEIVRTMQDGAGAVEHGKEVISATSDGMGRLSTQVQGVSVKMAQIAGILNQQSAASAEVAEG
VGAIAGLSARNVATINDVVEEMDGASKGIVAALNEMAALEIDDFTLHVAKSDHMLWRKRLADMVVGREVLNPDDLADHTK
CRLGKWCSTLTDESILRHPAYAALEAPHREVHRNGIDAARCFKNGDLDGALAAIARAAEASVGVMKCLDDLGDRRRF

Sequences:

>Translated_477_residues
MWTLGVGTQGDVMAWIFGGKTAAKADLRPMDVANDQALSSLQSESIGAALDQLLAGKYHSVPAGTCPVTAKIKALADRLE
SQAQANLRLDVGLSVNVNEAVTKAAGMMRDVGEVDRRAQAIAVAAEQLVSSVAEIARTSKAAAEDAGAAESVAQESHGAA
DQAIGAMQAIAEAVQAAAGKVDSLAEASVQIGDIVNQIEDIASQTNLLALNATIEAARAGEAGKGFAVVANEVKNLANQT
ARATVDIRARIESLRVEMGEIVRTMQDGAGAVEHGKEVISATSDGMGRLSTQVQGVSVKMAQIAGILNQQSAASAEVAEG
VGAIAGLSARNVATINDVVEEMDGASKGIVAALNEMAALEIDDFTLHVAKSDHMLWRKRLADMVVGREVLNPDDLADHTK
CRLGKWCSTLTDESILRHPAYAALEAPHREVHRNGIDAARCFKNGDLDGALAAIARAAEASVGVMKCLDDLGDRRRF
>Mature_477_residues
MWTLGVGTQGDVMAWIFGGKTAAKADLRPMDVANDQALSSLQSESIGAALDQLLAGKYHSVPAGTCPVTAKIKALADRLE
SQAQANLRLDVGLSVNVNEAVTKAAGMMRDVGEVDRRAQAIAVAAEQLVSSVAEIARTSKAAAEDAGAAESVAQESHGAA
DQAIGAMQAIAEAVQAAAGKVDSLAEASVQIGDIVNQIEDIASQTNLLALNATIEAARAGEAGKGFAVVANEVKNLANQT
ARATVDIRARIESLRVEMGEIVRTMQDGAGAVEHGKEVISATSDGMGRLSTQVQGVSVKMAQIAGILNQQSAASAEVAEG
VGAIAGLSARNVATINDVVEEMDGASKGIVAALNEMAALEIDDFTLHVAKSDHMLWRKRLADMVVGREVLNPDDLADHTK
CRLGKWCSTLTDESILRHPAYAALEAPHREVHRNGIDAARCFKNGDLDGALAAIARAAEASVGVMKCLDDLGDRRRF

Specific function: Signal Transducer For Aerotaxis. The Aerotactic Response Is The Accumulation Of Cells Around Air Bubbles. The Nature Of The Sensory Stimulus Detected By This Protein Is The Proton Motive Force Or Cellular Redox State. It Uses A FAD Prosthetic Group As A R

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=229, Percent_Identity=31.8777292576419, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1788195, Length=214, Percent_Identity=32.7102803738318, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI2367378, Length=219, Percent_Identity=34.703196347032, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1787690, Length=221, Percent_Identity=33.4841628959276, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1788194, Length=216, Percent_Identity=31.9444444444444, Blast_Score=86, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003018
- InterPro:   IPR003660
- InterPro:   IPR016132 [H]

Pfam domain/function: PF01590 GAF; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 49669; Mature: 49669

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWTLGVGTQGDVMAWIFGGKTAAKADLRPMDVANDQALSSLQSESIGAALDQLLAGKYHS
CEECCCCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
VPAGTCPVTAKIKALADRLESQAQANLRLDVGLSVNVNEAVTKAAGMMRDVGEVDRRAQA
CCCCCCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IAVAAEQLVSSVAEIARTSKAAAEDAGAAESVAQESHGAADQAIGAMQAIAEAVQAAAGK
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCC
VDSLAEASVQIGDIVNQIEDIASQTNLLALNATIEAARAGEAGKGFAVVANEVKNLANQT
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHCCCCCCCHHHHHHHHHHHHHHH
ARATVDIRARIESLRVEMGEIVRTMQDGAGAVEHGKEVISATSDGMGRLSTQVQGVSVKM
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHCCHHHHH
AQIAGILNQQSAASAEVAEGVGAIAGLSARNVATINDVVEEMDGASKGIVAALNEMAALE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHEE
IDDFTLHVAKSDHMLWRKRLADMVVGREVLNPDDLADHTKCRLGKWCSTLTDESILRHPA
ECCEEEEEECCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
YAALEAPHREVHRNGIDAARCFKNGDLDGALAAIARAAEASVGVMKCLDDLGDRRRF
HHHHCCCHHHHHHCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MWTLGVGTQGDVMAWIFGGKTAAKADLRPMDVANDQALSSLQSESIGAALDQLLAGKYHS
CEECCCCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
VPAGTCPVTAKIKALADRLESQAQANLRLDVGLSVNVNEAVTKAAGMMRDVGEVDRRAQA
CCCCCCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IAVAAEQLVSSVAEIARTSKAAAEDAGAAESVAQESHGAADQAIGAMQAIAEAVQAAAGK
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCC
VDSLAEASVQIGDIVNQIEDIASQTNLLALNATIEAARAGEAGKGFAVVANEVKNLANQT
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHCCCCCCCHHHHHHHHHHHHHHH
ARATVDIRARIESLRVEMGEIVRTMQDGAGAVEHGKEVISATSDGMGRLSTQVQGVSVKM
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHCCHHHHH
AQIAGILNQQSAASAEVAEGVGAIAGLSARNVATINDVVEEMDGASKGIVAALNEMAALE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHEE
IDDFTLHVAKSDHMLWRKRLADMVVGREVLNPDDLADHTKCRLGKWCSTLTDESILRHPA
ECCEEEEEECCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
YAALEAPHREVHRNGIDAARCFKNGDLDGALAAIARAAEASVGVMKCLDDLGDRRRF
HHHHCCCHHHHHHCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]