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The map label for this gene is aer [H]

Identifier: 83312201

GI number: 83312201

Start: 3354778

End: 3357003

Strand: Reverse

Name: aer [H]

Synonym: amb3102

Alternate gene names: 83312201

Gene position: 3357003-3354778 (Counterclockwise)

Preceding gene: 83312205

Following gene: 83312197

Centisome position: 67.58

GC content: 64.96

Gene sequence:

>2226_bases
ATGCCAAACGGCGTGATCTTGAGCGATCGTCCAGCCGGGTGGTCCAAACAAAATAGGGAGTGTCCGATGCGTGACAACGG
CGCGATCACCAACCGCGAGGTGGAACTGAAGGACGACGACATGCTGGTGTCGCGCACCGATGCCGGCGGCCGCATCACCT
TCGTGAACAAGGCCTTCATCGATATCAGCGGCTTTACCGAGCAGGAATTGCTGGGCTCGCCCCACAATCTGGTTCGCCAT
CCCCACATGCCCAAGGAGGCGTTCGCCGATCTGTGGGCCTCCATCAAGGCCGGACGGCCCTGGGAGGGCTACGTCAAGAA
CCGCACCAAGACCGGCGATCACTACTGGGTGCGGGCCAATGTCACCCCATTCATGGAAAAGGGCCAGATCGCCGGCTTCA
TCTCCATCCGCTCCAAGCCGACCCGGGCTCAGATCAATGCCGCCGAACAGGCATACGCGCTGTTTCGTGAAGGCAAGGCC
CGGGGCCTGGCCATTCGCGACGGGCGGGTGGTCTCCACCGGCCTGGGCGGCAGGGTTTCCGCCCTGAAGAATTCCATCGC
CGGACGCCTGTCCGGAGTGCTGGCCGTGCTGGGAGTGCTGATGCTGGTGGTGGGCTGGCTGGGCATTTCCGGCATGCGCG
GCATCGGCGAGGACATGCGCGAGGTCTATCTGGAGAACACCATGCCGGCCATCGATCTGGCCGAGGTCGCCGATCTGTCC
CAGGAAAACTATCGCCAGATCGCCAGCATCGCGGTGCAGATGCTGGCCAATCAGCATTGGGTGCCGGTGTCCGAGCGTCT
GGCCGCCATCGAGTCCAACTCGCAGATCATCAATCGCAAGTGGGAGCACTATGCCCAGGGCAGCCACCCGGCCGAGGAAC
TGGCACTGATCGAGAAATTCGCCAAGGCGCGCACGGCGTTCCGCGACCAGGGGCTGATTCCGGCGGTGGATCTGGTCCGC
AAGAACGATGCGGCGGCACTGTCCAAGCATTTCGGCGAGGCCATGCGGCCGCTCTACAACGCCAACCATGTCGCTCTCAA
GGGTTTGATCGACTATCAGAGCAAGGATGCCGGCAATACCTACGCCCGGGCCGAACAGCATCTGTCCTCGCGGACATTCC
TGGTGATCGGCGCCCTGGTGGTTGCCGTCGTTCTGGGCTTCATCCTCGCCGTCTGGATCCTGGCGGGCATCCGCAATCCC
CTGAAGGCCATGGAGCGGCATTTCGACGCCATCGCCTCGGGCAATCAGGCGCATGAAATCCCCGTGGCCGACATGCAGGA
ATTCGGGCAGCTCCATTCGCTGCTGCGGGCGCTCAAGGCCAAGCTGGGCTATTCCGCCCTGGAAAAGGCCGAACTGGACC
GCCAGGCCGAGGAGAACCGCAGGGCCGAGCTCAACCGCGTCGCCAAATCCCTGGAGGACCGGGTCAAGGGCGTGGTCGAT
CTGATCGACGTGTCGTCGGGCTCGCTGCTGGGCAATGCCCAGACCCTGTCGGCCAATGCCCAGCAGACCATGGTACAGGC
CGGCAACGTCACCGCCATGACCGGTCAGGTTACCGCCAATGTCCAGTCGGTGTCGGCGGCGACTCAGGAACTGTCGTCCT
CGGTGACCGAGATTTCCCGTCAGGTGGCCCATGCCGCCACCATCTCGGGCGATGCGGTGCGTCAGGCGGGCGAGACCGAC
CGCATGGTCCGCAGCCTCGCCGAGGCGGCCCAGAAGATCGGCGAGGTGGTCAACCTGATCACCGACATCGCCAGCCAGAC
CAACCTGCTGGCGCTCAACGCTACCATCGAGGCGGCGCGGGCAGGCGAAGCCGGCAAGGGCTTTGCCGTGGTCGCCAACG
AGGTCAAGCATCTGGCCAACCAGACCGCCAAGGCCACCGAGGAAATCGGCCAGCAGGTCACCGCCATTCAGGGCGAGACC
CGCTCGGCGGTGGAAGCCATCCGCTCCATCTCGGGAACCATCGAGAATATCAGCGAGCTGTCCTCGGCCATCGCCGCCGC
GGTGGAGGAGCAGGGCGCCGCCACCGCCGAGATCGCCCGCTCGGTGGAACAGGCGGCCCACGGCACCGCCTCCGCCGCCG
AAAATGTCGAGGTGGTCTCGGGGGCCGCCGAGGAGACCAAGCTGATGTCGGATCAGGTCTACGAGGCCGCCAACGGCCTC
AAGGGCGCCTCGAACCAGTTGGCCCAGGAGGTGGCGGGCTTCATCCGCGAAATCCGCAGCGCCTGA

Upstream 100 bases:

>100_bases
ACAGAAACTTTTCCGAGATATCTGAGTTTCCGAGTGGGATATTTTGACGGGCCGGCTTGAATATGTAAGTATGCGTACCA
TTCTAAGGGCCTGATGGTAT

Downstream 100 bases:

>100_bases
GCCGCGGGCGCGGGGAAAACATCAGGCCCCGGTCTTCTCGGCCGGGGCCTTTTGCTTGGCGGTGGCGTGTTCGATATAGT
GCCAGGCGAACAGGGCGGGC

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 741; Mature: 740

Protein sequence:

>741_residues
MPNGVILSDRPAGWSKQNRECPMRDNGAITNREVELKDDDMLVSRTDAGGRITFVNKAFIDISGFTEQELLGSPHNLVRH
PHMPKEAFADLWASIKAGRPWEGYVKNRTKTGDHYWVRANVTPFMEKGQIAGFISIRSKPTRAQINAAEQAYALFREGKA
RGLAIRDGRVVSTGLGGRVSALKNSIAGRLSGVLAVLGVLMLVVGWLGISGMRGIGEDMREVYLENTMPAIDLAEVADLS
QENYRQIASIAVQMLANQHWVPVSERLAAIESNSQIINRKWEHYAQGSHPAEELALIEKFAKARTAFRDQGLIPAVDLVR
KNDAAALSKHFGEAMRPLYNANHVALKGLIDYQSKDAGNTYARAEQHLSSRTFLVIGALVVAVVLGFILAVWILAGIRNP
LKAMERHFDAIASGNQAHEIPVADMQEFGQLHSLLRALKAKLGYSALEKAELDRQAEENRRAELNRVAKSLEDRVKGVVD
LIDVSSGSLLGNAQTLSANAQQTMVQAGNVTAMTGQVTANVQSVSAATQELSSSVTEISRQVAHAATISGDAVRQAGETD
RMVRSLAEAAQKIGEVVNLITDIASQTNLLALNATIEAARAGEAGKGFAVVANEVKHLANQTAKATEEIGQQVTAIQGET
RSAVEAIRSISGTIENISELSSAIAAAVEEQGAATAEIARSVEQAAHGTASAAENVEVVSGAAEETKLMSDQVYEAANGL
KGASNQLAQEVAGFIREIRSA

Sequences:

>Translated_741_residues
MPNGVILSDRPAGWSKQNRECPMRDNGAITNREVELKDDDMLVSRTDAGGRITFVNKAFIDISGFTEQELLGSPHNLVRH
PHMPKEAFADLWASIKAGRPWEGYVKNRTKTGDHYWVRANVTPFMEKGQIAGFISIRSKPTRAQINAAEQAYALFREGKA
RGLAIRDGRVVSTGLGGRVSALKNSIAGRLSGVLAVLGVLMLVVGWLGISGMRGIGEDMREVYLENTMPAIDLAEVADLS
QENYRQIASIAVQMLANQHWVPVSERLAAIESNSQIINRKWEHYAQGSHPAEELALIEKFAKARTAFRDQGLIPAVDLVR
KNDAAALSKHFGEAMRPLYNANHVALKGLIDYQSKDAGNTYARAEQHLSSRTFLVIGALVVAVVLGFILAVWILAGIRNP
LKAMERHFDAIASGNQAHEIPVADMQEFGQLHSLLRALKAKLGYSALEKAELDRQAEENRRAELNRVAKSLEDRVKGVVD
LIDVSSGSLLGNAQTLSANAQQTMVQAGNVTAMTGQVTANVQSVSAATQELSSSVTEISRQVAHAATISGDAVRQAGETD
RMVRSLAEAAQKIGEVVNLITDIASQTNLLALNATIEAARAGEAGKGFAVVANEVKHLANQTAKATEEIGQQVTAIQGET
RSAVEAIRSISGTIENISELSSAIAAAVEEQGAATAEIARSVEQAAHGTASAAENVEVVSGAAEETKLMSDQVYEAANGL
KGASNQLAQEVAGFIREIRSA
>Mature_740_residues
PNGVILSDRPAGWSKQNRECPMRDNGAITNREVELKDDDMLVSRTDAGGRITFVNKAFIDISGFTEQELLGSPHNLVRHP
HMPKEAFADLWASIKAGRPWEGYVKNRTKTGDHYWVRANVTPFMEKGQIAGFISIRSKPTRAQINAAEQAYALFREGKAR
GLAIRDGRVVSTGLGGRVSALKNSIAGRLSGVLAVLGVLMLVVGWLGISGMRGIGEDMREVYLENTMPAIDLAEVADLSQ
ENYRQIASIAVQMLANQHWVPVSERLAAIESNSQIINRKWEHYAQGSHPAEELALIEKFAKARTAFRDQGLIPAVDLVRK
NDAAALSKHFGEAMRPLYNANHVALKGLIDYQSKDAGNTYARAEQHLSSRTFLVIGALVVAVVLGFILAVWILAGIRNPL
KAMERHFDAIASGNQAHEIPVADMQEFGQLHSLLRALKAKLGYSALEKAELDRQAEENRRAELNRVAKSLEDRVKGVVDL
IDVSSGSLLGNAQTLSANAQQTMVQAGNVTAMTGQVTANVQSVSAATQELSSSVTEISRQVAHAATISGDAVRQAGETDR
MVRSLAEAAQKIGEVVNLITDIASQTNLLALNATIEAARAGEAGKGFAVVANEVKHLANQTAKATEEIGQQVTAIQGETR
SAVEAIRSISGTIENISELSSAIAAAVEEQGAATAEIARSVEQAAHGTASAAENVEVVSGAAEETKLMSDQVYEAANGLK
GASNQLAQEVAGFIREIRSA

Specific function: Signal transducer for aerotaxis. The aerotactic response is the accumulation of cells around air bubbles. The nature of the sensory stimulus detected by this protein is the proton motive force or cellular redox state. It uses a FAD prosthetic group as a r

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=185, Percent_Identity=42.7027027027027, Blast_Score=171, Evalue=2e-43,
Organism=Escherichia coli, GI1787690, Length=400, Percent_Identity=27.5, Blast_Score=108, Evalue=2e-24,
Organism=Escherichia coli, GI2367378, Length=341, Percent_Identity=29.9120234604106, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI1788194, Length=358, Percent_Identity=27.6536312849162, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1788195, Length=196, Percent_Identity=32.1428571428571, Blast_Score=88, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF08447 PAS_3 [H]

EC number: NA

Molecular weight: Translated: 79519; Mature: 79388

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS50192 T_SNARE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNGVILSDRPAGWSKQNRECPMRDNGAITNREVELKDDDMLVSRTDAGGRITFVNKAFI
CCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEECCCCCEEEEEEEEEE
DISGFTEQELLGSPHNLVRHPHMPKEAFADLWASIKAGRPWEGYVKNRTKTGDHYWVRAN
EECCCCHHHHCCCCHHHHCCCCCCHHHHHHHHHHHCCCCCCCHHHCCCCCCCCEEEEEEC
VTPFMEKGQIAGFISIRSKPTRAQINAAEQAYALFREGKARGLAIRDGRVVSTGLGGRVS
CCCCHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCEEEECCCCCHHH
ALKNSIAGRLSGVLAVLGVLMLVVGWLGISGMRGIGEDMREVYLENTMPAIDLAEVADLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHCC
QENYRQIASIAVQMLANQHWVPVSERLAAIESNSQIINRKWEHYAQGSHPAEELALIEKF
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHH
AKARTAFRDQGLIPAVDLVRKNDAAALSKHFGEAMRPLYNANHVALKGLIDYQSKDAGNT
HHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCH
YARAEQHLSSRTFLVIGALVVAVVLGFILAVWILAGIRNPLKAMERHFDAIASGNQAHEI
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCC
PVADMQEFGQLHSLLRALKAKLGYSALEKAELDRQAEENRRAELNRVAKSLEDRVKGVVD
CHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIDVSSGSLLGNAQTLSANAQQTMVQAGNVTAMTGQVTANVQSVSAATQELSSSVTEISR
HHCCCCCCCCCCCHHCCCCHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHH
QVAHAATISGDAVRQAGETDRMVRSLAEAAQKIGEVVNLITDIASQTNLLALNATIEAAR
HHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHH
AGEAGKGFAVVANEVKHLANQTAKATEEIGQQVTAIQGETRSAVEAIRSISGTIENISEL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
SSAIAAAVEEQGAATAEIARSVEQAAHGTASAAENVEVVSGAAEETKLMSDQVYEAANGL
HHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHCCHHHHCCCHHHHHHHHHHHHHHHCCC
KGASNQLAQEVAGFIREIRSA
CCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PNGVILSDRPAGWSKQNRECPMRDNGAITNREVELKDDDMLVSRTDAGGRITFVNKAFI
CCCCEECCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEECCCCCEEEEEEEEEE
DISGFTEQELLGSPHNLVRHPHMPKEAFADLWASIKAGRPWEGYVKNRTKTGDHYWVRAN
EECCCCHHHHCCCCHHHHCCCCCCHHHHHHHHHHHCCCCCCCHHHCCCCCCCCEEEEEEC
VTPFMEKGQIAGFISIRSKPTRAQINAAEQAYALFREGKARGLAIRDGRVVSTGLGGRVS
CCCCHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCEEEECCCCCHHH
ALKNSIAGRLSGVLAVLGVLMLVVGWLGISGMRGIGEDMREVYLENTMPAIDLAEVADLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHCC
QENYRQIASIAVQMLANQHWVPVSERLAAIESNSQIINRKWEHYAQGSHPAEELALIEKF
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHH
AKARTAFRDQGLIPAVDLVRKNDAAALSKHFGEAMRPLYNANHVALKGLIDYQSKDAGNT
HHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCH
YARAEQHLSSRTFLVIGALVVAVVLGFILAVWILAGIRNPLKAMERHFDAIASGNQAHEI
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCC
PVADMQEFGQLHSLLRALKAKLGYSALEKAELDRQAEENRRAELNRVAKSLEDRVKGVVD
CHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIDVSSGSLLGNAQTLSANAQQTMVQAGNVTAMTGQVTANVQSVSAATQELSSSVTEISR
HHCCCCCCCCCCCHHCCCCHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHH
QVAHAATISGDAVRQAGETDRMVRSLAEAAQKIGEVVNLITDIASQTNLLALNATIEAAR
HHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHH
AGEAGKGFAVVANEVKHLANQTAKATEEIGQQVTAIQGETRSAVEAIRSISGTIENISEL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
SSAIAAAVEEQGAATAEIARSVEQAAHGTASAAENVEVVSGAAEETKLMSDQVYEAANGL
HHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHCCHHHHCCCHHHHHHHHHHHHHHHCCC
KGASNQLAQEVAGFIREIRSA
CCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 9190831; 9380671 [H]