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The map label for this gene is aphA [H]

Identifier: 83311975

GI number: 83311975

Start: 3075913

End: 3077595

Strand: Reverse

Name: aphA [H]

Synonym: amb2876

Alternate gene names: 83311975

Gene position: 3077595-3075913 (Counterclockwise)

Preceding gene: 83311977

Following gene: 83311973

Centisome position: 61.96

GC content: 63.93

Gene sequence:

>1683_bases
GTGGCAAGCGTCGCTATGGATTACAACAGGTTCAAGGCCTCTCGCTGGCGGTTGGTGGCGTTGCTGCTGTTCGTCAATGC
GTCCGTGCTGGGCTTGGCCTGGATTTCCCTCGATGCCAGCTACCGGCAATACCAGGACCGCGCCGCGGTTTCGTCGCGCA
ACACCAACCGCCTAGTCTCGCAGAGCATTGCTGGCGACATCGGTCAGATCGATCTGGCCCTGCGCAGTGCCAGCGACGAG
GTGACGCGTGTCTACCGGTCCGGCGGCGCTATTGCCGGCCCGGAGATGACCGGCTTCCTCGCCCGGCTGCAAAGCCGCCT
GAAGATGGCGGACGGCCTTCGGTTCACCAATGCGGCCGGCGTGGTGATCGCCAGTGCCGACATGTCCGGATATGGGACCG
ATATCGGTGACCGCGAGTATTTCCTCGCCCATCGCGACAATCCGGGATTCGGCCTGGCCATCTCGCCGCCGACTCTGGGT
CGCATCAGCAACAAATGGGTGCTGATCTTCGCGAGGCGTCTGGAATACGCTGATGGCAGCTTCGCCGGCATCGTCTTTGC
CCCGGTGACCATTTCCTGGTTCGAGCAGAAATTCAACAATCTCGAGGTGGGGCCGCAGGGCACGGTGGTCATGCGCGGCG
ACGCCTCGCGCAATTTCGATCTGCTGGCCCGCTTTCCCCATGCGGGCTATGTGGGGCAGACCACGGTCTCCAACACCTTC
CGCGAGCGGATCACCGCCAACCCGCAAGGGGGGACCTACGAGGCCTCGGCGGGCGCCGACAATATCCGGCGGACCTTCTC
GTACCAGCCCATCGCCAATTACCCCCTGATCACCCTGGTGGGCATGGCCACCGAGGATTACCTGGGCGAATGGCGCAAGG
AGGGCATCAAGGTGATCGTCCTGGCCGGCGCCTTCATCATCGTCACCACATTGGGCGGATTCGGCATGTTGCGCAGTTGG
CGCACCTTGGAACTGCAGACCGATGAACTGGCGCGGTCCAATGCCGATCTCGAGCAGTTCGCCTACGTGGCGTCCCACGA
CCTGCAGACGCCGCTGCGCAACATCGCCAGCTATGCGCAATTGCTGGCACGGCGCTACGAGGGGCGGCTGGACAAGGATG
CCGACGAGTTCATCGGCTACATCGTCGGCGGCGCCAAGCACATGTCGTCGATGATTCCCGATCTTCTCGACTATGCCCGC
GTTTCGCGCTCGCCGCCGGAATTCGTGCCGGTGGATCTCAATGCGGTGGTCAAATCGGTGCTGACCAATCTCGGCCCGGA
TCTGCAGGCTTCGGGCGCCACCGTCACCATGGACGCGCTTCCCGTGGTTCTGGCCGAGGCGCGGCAGGCGGAAAGCCTGT
TCCAGAACCTGCTGGAAAACGCGCTGATCTACCGCAAGCCCGATGCGCCCCCGCAGATCGAGATCAAGGCCACGCTGGAG
CCCAAGGGGCTGTGGCTCATCTCGGTCCGCGACAACGGCATCGGCATCGAGCCGGCCTATTTCGAGAAGATCTTCGTCAT
CTTCCAGCGGCTGGAACCGGCCCGCTTCCCCGGTGGAACCGGCATCGGCCTGGCGCTGTGCCGCCGCATCGTGCACCGGT
TCGGCGGCTCCATCTGGGTGGAGTCCGAACCCCAGAAAGGCACCACCTTCAACTTCACGCTCCGCCCCAGCACGGGAAGC
TGA

Upstream 100 bases:

>100_bases
ATTTAGCGTTGCAATGGTATGGGAACGTCTGGGCAAGCCTATTGGCTTGAGGTAAGGTGATTTCTCTGCGCTGTTGCCCT
TCTGGGGAGGGAGGACAAAG

Downstream 100 bases:

>100_bases
GGCGGAGGCCGCAGCGACGGCGGCTCAGCGTTCCGGGGTGATGTGGACCTCGAGTTCACCCACGCCCTCGATGGCGCCCC
GCAGGACATCACCGGCCACC

Product: Signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 560; Mature: 559

Protein sequence:

>560_residues
MASVAMDYNRFKASRWRLVALLLFVNASVLGLAWISLDASYRQYQDRAAVSSRNTNRLVSQSIAGDIGQIDLALRSASDE
VTRVYRSGGAIAGPEMTGFLARLQSRLKMADGLRFTNAAGVVIASADMSGYGTDIGDREYFLAHRDNPGFGLAISPPTLG
RISNKWVLIFARRLEYADGSFAGIVFAPVTISWFEQKFNNLEVGPQGTVVMRGDASRNFDLLARFPHAGYVGQTTVSNTF
RERITANPQGGTYEASAGADNIRRTFSYQPIANYPLITLVGMATEDYLGEWRKEGIKVIVLAGAFIIVTTLGGFGMLRSW
RTLELQTDELARSNADLEQFAYVASHDLQTPLRNIASYAQLLARRYEGRLDKDADEFIGYIVGGAKHMSSMIPDLLDYAR
VSRSPPEFVPVDLNAVVKSVLTNLGPDLQASGATVTMDALPVVLAEARQAESLFQNLLENALIYRKPDAPPQIEIKATLE
PKGLWLISVRDNGIGIEPAYFEKIFVIFQRLEPARFPGGTGIGLALCRRIVHRFGGSIWVESEPQKGTTFNFTLRPSTGS

Sequences:

>Translated_560_residues
MASVAMDYNRFKASRWRLVALLLFVNASVLGLAWISLDASYRQYQDRAAVSSRNTNRLVSQSIAGDIGQIDLALRSASDE
VTRVYRSGGAIAGPEMTGFLARLQSRLKMADGLRFTNAAGVVIASADMSGYGTDIGDREYFLAHRDNPGFGLAISPPTLG
RISNKWVLIFARRLEYADGSFAGIVFAPVTISWFEQKFNNLEVGPQGTVVMRGDASRNFDLLARFPHAGYVGQTTVSNTF
RERITANPQGGTYEASAGADNIRRTFSYQPIANYPLITLVGMATEDYLGEWRKEGIKVIVLAGAFIIVTTLGGFGMLRSW
RTLELQTDELARSNADLEQFAYVASHDLQTPLRNIASYAQLLARRYEGRLDKDADEFIGYIVGGAKHMSSMIPDLLDYAR
VSRSPPEFVPVDLNAVVKSVLTNLGPDLQASGATVTMDALPVVLAEARQAESLFQNLLENALIYRKPDAPPQIEIKATLE
PKGLWLISVRDNGIGIEPAYFEKIFVIFQRLEPARFPGGTGIGLALCRRIVHRFGGSIWVESEPQKGTTFNFTLRPSTGS
>Mature_559_residues
ASVAMDYNRFKASRWRLVALLLFVNASVLGLAWISLDASYRQYQDRAAVSSRNTNRLVSQSIAGDIGQIDLALRSASDEV
TRVYRSGGAIAGPEMTGFLARLQSRLKMADGLRFTNAAGVVIASADMSGYGTDIGDREYFLAHRDNPGFGLAISPPTLGR
ISNKWVLIFARRLEYADGSFAGIVFAPVTISWFEQKFNNLEVGPQGTVVMRGDASRNFDLLARFPHAGYVGQTTVSNTFR
ERITANPQGGTYEASAGADNIRRTFSYQPIANYPLITLVGMATEDYLGEWRKEGIKVIVLAGAFIIVTTLGGFGMLRSWR
TLELQTDELARSNADLEQFAYVASHDLQTPLRNIASYAQLLARRYEGRLDKDADEFIGYIVGGAKHMSSMIPDLLDYARV
SRSPPEFVPVDLNAVVKSVLTNLGPDLQASGATVTMDALPVVLAEARQAESLFQNLLENALIYRKPDAPPQIEIKATLEP
KGLWLISVRDNGIGIEPAYFEKIFVIFQRLEPARFPGGTGIGLALCRRIVHRFGGSIWVESEPQKGTTFNFTLRPSTGS

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=262, Percent_Identity=27.0992366412214, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1786912, Length=242, Percent_Identity=31.8181818181818, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789149, Length=232, Percent_Identity=25.4310344827586, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI87081816, Length=223, Percent_Identity=28.6995515695067, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788549, Length=237, Percent_Identity=27.8481012658228, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1790436, Length=271, Percent_Identity=26.1992619926199, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI145693157, Length=272, Percent_Identity=25.3676470588235, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1788713, Length=243, Percent_Identity=22.2222222222222, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI1790346, Length=209, Percent_Identity=28.7081339712919, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 61505; Mature: 61374

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASVAMDYNRFKASRWRLVALLLFVNASVLGLAWISLDASYRQYQDRAAVSSRNTNRLVS
CCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHEEEEEECCHHHHHHHHHHHHCCCHHHHHH
QSIAGDIGQIDLALRSASDEVTRVYRSGGAIAGPEMTGFLARLQSRLKMADGLRFTNAAG
HHHCCCCCCEEHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCEEECCCC
VVIASADMSGYGTDIGDREYFLAHRDNPGFGLAISPPTLGRISNKWVLIFARRLEYADGS
EEEEECCCCCCCCCCCCCEEEEEECCCCCEEEEECCCCCCCCCCCEEEEEEEHHCCCCCC
FAGIVFAPVTISWFEQKFNNLEVGPQGTVVMRGDASRNFDLLARFPHAGYVGQTTVSNTF
EEEEEEECCHHHHHHHHHCCCCCCCCCCEEEECCCCCCCHHEEECCCCCCCCCHHHHHHH
RERITANPQGGTYEASAGADNIRRTFSYQPIANYPLITLVGMATEDYLGEWRKEGIKVIV
HHHHCCCCCCCEEECCCCCHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHCCCEEEE
LAGAFIIVTTLGGFGMLRSWRTLELQTDELARSNADLEQFAYVASHDLQTPLRNIASYAQ
EHHHHHHHHHHCCHHHHCCCEEEEEEHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LLARRYEGRLDKDADEFIGYIVGGAKHMSSMIPDLLDYARVSRSPPEFVPVDLNAVVKSV
HHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHH
LTNLGPDLQASGATVTMDALPVVLAEARQAESLFQNLLENALIYRKPDAPPQIEIKATLE
HHHCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCEEEEEEEC
PKGLWLISVRDNGIGIEPAYFEKIFVIFQRLEPARFPGGTGIGLALCRRIVHRFGGSIWV
CCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCEEEE
ESEPQKGTTFNFTLRPSTGS
ECCCCCCCEEEEEECCCCCC
>Mature Secondary Structure 
ASVAMDYNRFKASRWRLVALLLFVNASVLGLAWISLDASYRQYQDRAAVSSRNTNRLVS
CCCCCCHHHHHHHHHHHHHHHHHHCCHHHHEEEEEECCHHHHHHHHHHHHCCCHHHHHH
QSIAGDIGQIDLALRSASDEVTRVYRSGGAIAGPEMTGFLARLQSRLKMADGLRFTNAAG
HHHCCCCCCEEHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCEEECCCC
VVIASADMSGYGTDIGDREYFLAHRDNPGFGLAISPPTLGRISNKWVLIFARRLEYADGS
EEEEECCCCCCCCCCCCCEEEEEECCCCCEEEEECCCCCCCCCCCEEEEEEEHHCCCCCC
FAGIVFAPVTISWFEQKFNNLEVGPQGTVVMRGDASRNFDLLARFPHAGYVGQTTVSNTF
EEEEEEECCHHHHHHHHHCCCCCCCCCCEEEECCCCCCCHHEEECCCCCCCCCHHHHHHH
RERITANPQGGTYEASAGADNIRRTFSYQPIANYPLITLVGMATEDYLGEWRKEGIKVIV
HHHHCCCCCCCEEECCCCCHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHCCCEEEE
LAGAFIIVTTLGGFGMLRSWRTLELQTDELARSNADLEQFAYVASHDLQTPLRNIASYAQ
EHHHHHHHHHHCCHHHHCCCEEEEEEHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LLARRYEGRLDKDADEFIGYIVGGAKHMSSMIPDLLDYARVSRSPPEFVPVDLNAVVKSV
HHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHH
LTNLGPDLQASGATVTMDALPVVLAEARQAESLFQNLLENALIYRKPDAPPQIEIKATLE
HHHCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCEEEEEEEC
PKGLWLISVRDNGIGIEPAYFEKIFVIFQRLEPARFPGGTGIGLALCRRIVHRFGGSIWV
CCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCEEEE
ESEPQKGTTFNFTLRPSTGS
ECCCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]