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The map label for this gene is mcpA [H]

Identifier: 83311887

GI number: 83311887

Start: 2974025

End: 2976097

Strand: Reverse

Name: mcpA [H]

Synonym: amb2788

Alternate gene names: 83311887

Gene position: 2976097-2974025 (Counterclockwise)

Preceding gene: 83311888

Following gene: 83311886

Centisome position: 59.92

GC content: 65.89

Gene sequence:

>2073_bases
ATGAAGGTCAGAAGCCTGTTCGTGCTGTTCGTGGCGCTGGTCGCCGCGGTTTTTCTGGTTGCCTCCATCACCATGGTGAT
GAGCGCGTATCAGGAGCGCGCCCAGGTGGCCGCCGCCTATCGAGGGGTCGGTCTCCAGGGCGCCCTGTTGCGTCTGGCCG
AGCGGATCAATTTCGAGCGCGGTCTCTACAATGTCTCCCTGATCAACAAGCAGACGCTTAGCCCCGAGCTTACCGCGCGG
CTGAAGGGGTTGGCCGACGACAGTGACACGTCCTTCGCCGCGGCGCAGGCCGCGGCGAAAGGCGGGGCAGCCGTGAACGA
TCTGCTGCGCGCCCAGCAAGATCGCATCAAGGCGTCGCGGGAGATGGTGGTACGGCAACTGGGCTCCGGCGCTCCGGAAG
GCCACGCCGAGGTGGCCAAGGCCTACTCCGCCCTGAACATTTCCATCGGCGACGCCATCCGGCACGAGGCGCAGGGTTTG
ATCCCCGAGCTGAACAAACAGTCGGGTCCCTTGTCCGACTATGTGGTGCTGGCTCATGCGGCGAGCCGCATGCGCAATCT
CGCGGGCCAGAGAAATACGCCGCTGCTGCCGGTGATTCAGGCCGGCGTGCAGATGACGCCGGACCATCTGGAGAGGCATT
ACCGCCTGAATGGCCGGTTGGCCGAGGCCTGGGAGGATGTCCAGGCCAAATCCAAGACGCTGGCCCTCTCCAGCCCCGAG
ATCGACCAGGGGCTGAAAAATGTGGAGACGGCCTTCTTCGGCGCGGTGGAATCCATGGTCCGGGAGCTTGAAAAGGCCCA
TTGGCAAAAGCAGCCCTATCCCTTCGACGTCAACGACTACCGCACCCGGACGGTGGAGAAGTTCGCCACCTTCAGCCAGT
TGGGCGACGCCTATATCGCCACGGCCCTGCGGCTGGGAGAGCAGCGTCTGGCTGGGCTTTCCGTGTCGTTGGCCCTGTTG
TCCGTGGGCATCGCCGTTGTGGTCGCTCTGTTTTGCGTCGCCACCATCGTGTTCAACCGGCGGGTCGTGTCGCCGCTGAT
CGGCACGGCGGGAACCATCACCCATCTCGCCAATGACCAGCTGGACATCGACATTCCCTGGAGGGACCGCGGCGACGAGA
TCGGAGAAATCGGAAGAGCGCTGGAGACGCTGCGGGGCAACGCGAAGGCGGCCCGGTCGGTGGCCGAGGACAGAACTCGC
GAGCGTCTGGCCAGCGATGAGGTCCGGCATGGGGTGGACGTCGCCGTCCGGACTTTCGCCGACCGCATCGCGGGTCTGAT
GAAGAGTTCCGACGACAGCATGGGATCGCTCCGCCAGTACGCTCGGGATCTCAGTCGGCTGGCCGGCGATGCCTCGGGCG
GGTCCGGCGAAGTGGCCCGGGCCGCCGATGGGGCTGCCACCAACGTGCAGGGGATCGCTTCGGCGACCTCGGAGCTGCTC
TCCTCCATCGGCGAGATCAGTCAGGTGGTGGCCGACATGGCGGGGATTTCCAGGCAGGCGGTGGATGAGGCTCGCGCCTC
GCGCCAGGCCGTGGAGGAACTGACCCAGTCGGCGGGCCGCATCGGCGAGATCGTGGCCCTGATCAATGATATTGCCGCGC
AGACCAATCTGCTGGCGCTCAATGCCACCATCGAGGCGGCCCGCGCCGGCGAGGCGGGCAAGGGTTTCGCCGTGGTGGCC
AACGAGGTGAAGGTGCTGGCCAATCAGACTGGCAAGGCCACGGAGCAGATTCAAGGGCAGGTGGGCGCCATCCAGCGCGG
CACGGCCACGGCATCTCACTCCATCGCCGGAATCGACAGCACCGTGGGGCGCATCAGCGAGATGGCGACCTCCATCGCCT
CGGCGGTCGAGGAACAGAATGCCGCGACGAGCGAGATTGCCAGTTCGATCCAGCAGGCCTCCGACGGGGTGGGCGCGGTG
GCGGGAACCATCACCCATGTGCGGGAAAATGCGGCGTCCACGGATCGGGCCGCCGAATCGGTTCAGGCCGCCGCCGAGCG
TCTGGCGGCGAACACCGCAGCCCTGCACCAGGAATTTGATCAGATGGTGGAGTTGATCCGGCGATCGGCGTGA

Upstream 100 bases:

>100_bases
TGGTGCGTGCCGAAGCGTCGTTGTTCATGGGATTTAGAAGCGATGCCGTGCGCCTGATTGGTGAATATCCGTTTGGCCAT
GGTGGGTCAAAGGGGGGGAT

Downstream 100 bases:

>100_bases
TACGAGGCGGCGCGGAGTCAGCATTCAGCCCGTTTAGCAAGTGCAAAATGGCATTCGAATGCCGGCTTGTTTGCTTGACA
GGCCCTGGGGGGTGGATTAA

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 690; Mature: 690

Protein sequence:

>690_residues
MKVRSLFVLFVALVAAVFLVASITMVMSAYQERAQVAAAYRGVGLQGALLRLAERINFERGLYNVSLINKQTLSPELTAR
LKGLADDSDTSFAAAQAAAKGGAAVNDLLRAQQDRIKASREMVVRQLGSGAPEGHAEVAKAYSALNISIGDAIRHEAQGL
IPELNKQSGPLSDYVVLAHAASRMRNLAGQRNTPLLPVIQAGVQMTPDHLERHYRLNGRLAEAWEDVQAKSKTLALSSPE
IDQGLKNVETAFFGAVESMVRELEKAHWQKQPYPFDVNDYRTRTVEKFATFSQLGDAYIATALRLGEQRLAGLSVSLALL
SVGIAVVVALFCVATIVFNRRVVSPLIGTAGTITHLANDQLDIDIPWRDRGDEIGEIGRALETLRGNAKAARSVAEDRTR
ERLASDEVRHGVDVAVRTFADRIAGLMKSSDDSMGSLRQYARDLSRLAGDASGGSGEVARAADGAATNVQGIASATSELL
SSIGEISQVVADMAGISRQAVDEARASRQAVEELTQSAGRIGEIVALINDIAAQTNLLALNATIEAARAGEAGKGFAVVA
NEVKVLANQTGKATEQIQGQVGAIQRGTATASHSIAGIDSTVGRISEMATSIASAVEEQNAATSEIASSIQQASDGVGAV
AGTITHVRENAASTDRAAESVQAAAERLAANTAALHQEFDQMVELIRRSA

Sequences:

>Translated_690_residues
MKVRSLFVLFVALVAAVFLVASITMVMSAYQERAQVAAAYRGVGLQGALLRLAERINFERGLYNVSLINKQTLSPELTAR
LKGLADDSDTSFAAAQAAAKGGAAVNDLLRAQQDRIKASREMVVRQLGSGAPEGHAEVAKAYSALNISIGDAIRHEAQGL
IPELNKQSGPLSDYVVLAHAASRMRNLAGQRNTPLLPVIQAGVQMTPDHLERHYRLNGRLAEAWEDVQAKSKTLALSSPE
IDQGLKNVETAFFGAVESMVRELEKAHWQKQPYPFDVNDYRTRTVEKFATFSQLGDAYIATALRLGEQRLAGLSVSLALL
SVGIAVVVALFCVATIVFNRRVVSPLIGTAGTITHLANDQLDIDIPWRDRGDEIGEIGRALETLRGNAKAARSVAEDRTR
ERLASDEVRHGVDVAVRTFADRIAGLMKSSDDSMGSLRQYARDLSRLAGDASGGSGEVARAADGAATNVQGIASATSELL
SSIGEISQVVADMAGISRQAVDEARASRQAVEELTQSAGRIGEIVALINDIAAQTNLLALNATIEAARAGEAGKGFAVVA
NEVKVLANQTGKATEQIQGQVGAIQRGTATASHSIAGIDSTVGRISEMATSIASAVEEQNAATSEIASSIQQASDGVGAV
AGTITHVRENAASTDRAAESVQAAAERLAANTAALHQEFDQMVELIRRSA
>Mature_690_residues
MKVRSLFVLFVALVAAVFLVASITMVMSAYQERAQVAAAYRGVGLQGALLRLAERINFERGLYNVSLINKQTLSPELTAR
LKGLADDSDTSFAAAQAAAKGGAAVNDLLRAQQDRIKASREMVVRQLGSGAPEGHAEVAKAYSALNISIGDAIRHEAQGL
IPELNKQSGPLSDYVVLAHAASRMRNLAGQRNTPLLPVIQAGVQMTPDHLERHYRLNGRLAEAWEDVQAKSKTLALSSPE
IDQGLKNVETAFFGAVESMVRELEKAHWQKQPYPFDVNDYRTRTVEKFATFSQLGDAYIATALRLGEQRLAGLSVSLALL
SVGIAVVVALFCVATIVFNRRVVSPLIGTAGTITHLANDQLDIDIPWRDRGDEIGEIGRALETLRGNAKAARSVAEDRTR
ERLASDEVRHGVDVAVRTFADRIAGLMKSSDDSMGSLRQYARDLSRLAGDASGGSGEVARAADGAATNVQGIASATSELL
SSIGEISQVVADMAGISRQAVDEARASRQAVEELTQSAGRIGEIVALINDIAAQTNLLALNATIEAARAGEAGKGFAVVA
NEVKVLANQTGKATEQIQGQVGAIQRGTATASHSIAGIDSTVGRISEMATSIASAVEEQNAATSEIASSIQQASDGVGAV
AGTITHVRENAASTDRAAESVQAAAERLAANTAALHQEFDQMVELIRRSA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=371, Percent_Identity=28.8409703504043, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1787690, Length=338, Percent_Identity=26.6272189349112, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI2367378, Length=219, Percent_Identity=31.9634703196347, Blast_Score=92, Evalue=2e-19,
Organism=Escherichia coli, GI1788195, Length=200, Percent_Identity=31, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1789453, Length=118, Percent_Identity=41.5254237288136, Blast_Score=81, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 72987; Mature: 72987

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS50192 T_SNARE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVRSLFVLFVALVAAVFLVASITMVMSAYQERAQVAAAYRGVGLQGALLRLAERINFER
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
GLYNVSLINKQTLSPELTARLKGLADDSDTSFAAAQAAAKGGAAVNDLLRAQQDRIKASR
CCEEEEECCCHHCCHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
EMVVRQLGSGAPEGHAEVAKAYSALNISIGDAIRHEAQGLIPELNKQSGPLSDYVVLAHA
HHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
ASRMRNLAGQRNTPLLPVIQAGVQMTPDHLERHYRLNGRLAEAWEDVQAKSKTLALSSPE
HHHHHHHCCCCCCCCHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHEECCCCC
IDQGLKNVETAFFGAVESMVRELEKAHWQKQPYPFDVNDYRTRTVEKFATFSQLGDAYIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
TALRLGEQRLAGLSVSLALLSVGIAVVVALFCVATIVFNRRVVSPLIGTAGTITHLANDQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCC
LDIDIPWRDRGDEIGEIGRALETLRGNAKAARSVAEDRTRERLASDEVRHGVDVAVRTFA
EEEECCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DRIAGLMKSSDDSMGSLRQYARDLSRLAGDASGGSGEVARAADGAATNVQGIASATSELL
HHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHH
SSIGEISQVVADMAGISRQAVDEARASRQAVEELTQSAGRIGEIVALINDIAAQTNLLAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEE
NATIEAARAGEAGKGFAVVANEVKVLANQTGKATEQIQGQVGAIQRGTATASHSIAGIDS
ECHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHCCCHHCHHH
TVGRISEMATSIASAVEEQNAATSEIASSIQQASDGVGAVAGTITHVRENAASTDRAAES
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCHHHHHHHH
VQAAAERLAANTAALHQEFDQMVELIRRSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKVRSLFVLFVALVAAVFLVASITMVMSAYQERAQVAAAYRGVGLQGALLRLAERINFER
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
GLYNVSLINKQTLSPELTARLKGLADDSDTSFAAAQAAAKGGAAVNDLLRAQQDRIKASR
CCEEEEECCCHHCCHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
EMVVRQLGSGAPEGHAEVAKAYSALNISIGDAIRHEAQGLIPELNKQSGPLSDYVVLAHA
HHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
ASRMRNLAGQRNTPLLPVIQAGVQMTPDHLERHYRLNGRLAEAWEDVQAKSKTLALSSPE
HHHHHHHCCCCCCCCHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHEECCCCC
IDQGLKNVETAFFGAVESMVRELEKAHWQKQPYPFDVNDYRTRTVEKFATFSQLGDAYIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
TALRLGEQRLAGLSVSLALLSVGIAVVVALFCVATIVFNRRVVSPLIGTAGTITHLANDQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCC
LDIDIPWRDRGDEIGEIGRALETLRGNAKAARSVAEDRTRERLASDEVRHGVDVAVRTFA
EEEECCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DRIAGLMKSSDDSMGSLRQYARDLSRLAGDASGGSGEVARAADGAATNVQGIASATSELL
HHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHH
SSIGEISQVVADMAGISRQAVDEARASRQAVEELTQSAGRIGEIVALINDIAAQTNLLAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEE
NATIEAARAGEAGKGFAVVANEVKVLANQTGKATEQIQGQVGAIQRGTATASHSIAGIDS
ECHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHCCCHHCHHH
TVGRISEMATSIASAVEEQNAATSEIASSIQQASDGVGAVAGTITHVRENAASTDRAAES
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCHHHHHHHH
VQAAAERLAANTAALHQEFDQMVELIRRSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]