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The map label for this gene is actP

Identifier: 83311725

GI number: 83311725

Start: 2812356

End: 2814020

Strand: Reverse

Name: actP

Synonym: amb2626

Alternate gene names: 83311725

Gene position: 2814020-2812356 (Counterclockwise)

Preceding gene: 83311726

Following gene: 83311724

Centisome position: 56.65

GC content: 65.23

Gene sequence:

>1665_bases
ATGAAGCGGATTCTCCCCATCCTGCTGGCGCTGGCGGTTCCCACCGCTGCCCTGGCCGGTCCCGGCGACCTCGGCGGTTC
CGAGAAGCAGCCGATCAACGTCACCGCCATCGCCATGTTCTTCGCCTTCGTCATGGGCACGCTGGGCATCACCTATTGGG
CGTCCAAGCGCACCAAGTCGGCGTCCGACTTCTACACGGCGGGCGGCGGCATCACCGGCTTCCAGAACGGTCTGGCCATC
GCTGGCGACTATATGTCGGCCGCGACCCTGCTGGGCCTGTCCTCCATGGTGTTCGCCACCGGCTTCGATGGCTTCATCTA
TACCATCAGCTTCTTCGTCGGCTGGCCGATCATCCTGTTCCTGCTGGCCGAGCGCCTGCGGAACCTGGGCCGCTACACCT
TCGCCGACATCGCCTCCTACCGTCTCGACCAGTCCAAGGTGCGCACCTTTGCCGCCATGGGCTCGCTGACCGTGGTGTGC
TTCTACCTGATCGTCCAGATGGTCGGCGCCGGTCAGCTGATCAAGCTGCTGTTCGGCCTGGATTATGCCGTGGCGGTGAT
CATCGTCGGCGTGCTGATGGTGGTCTATGTCACTTTCGGCGGCATGATCGCCACCACCTGGGTGCAGATCATCAAGGCCT
GCCTGCTGCTGGGCGGCGGCGTGCTGCTCTGCGCCCTGGCGCTGTCCAAGTTCGGCTTCAGCCTGGAAAACGTCGCCGCC
AAGGCGGTGGAGTCCCATAAGGCGGGCGTCAAGATCATGGGCCCCGGCACCATGCTGGCCGATCCGGTTTCGGCGGTGTC
GCTGTCGCTGGGTCTGGTGTTCGGCACCGCCGCGCTGCCGCACATCCTGATGCGCTTCTTCACCGTTCCCAACGCCAAGG
AAGCGCGCAAGAGCGTGTTCGTGGCCTCGGGCTTCATCGGCTTCTTCTTCCTGATCGTCTGCATTCTCGGCCTGGCCGCG
GTCAGCATCGTCGGCACCGATCCGCAGTTCTTCGAAGGCGGCAAGGTGGGCGGCAAGCTGCTGGGCGGCGGCAACATGCC
GGTGATGCATCTGGCCAAGGCCCTGGGCGGCGACATCTTCCTGGGCTTCCTGTCGGCGGTGGCCTTCGCCACCATCCTGG
CGGTGGTGTCGGGTCTGGCCCTGGCCGGCGCCTCGGCCATCGCCCACGACATCTATGCCCGCGTCATCCGCAAGGGTCAC
GCCACCGAGGCCGAGGAGATGCGAGTCTCCAAGCTCTCCTCGCTGGTGCTGGGCGTGGTCGCGGTGATTCTGGGCATCAT
GTTCGAGAAGCAGAACGTCGCCTTCTTGGTGGGCCTGACCTTCGGCATCGCGGCCTCGGCCAACTTTCCGGTGCTGTTCC
TGTCCATGTACTGGCGGGGCCTGACCACCAAGGGCGCCCTGTGGGGCGGCATTGCCGGCCTGGTGTCGGCGGTGACCTGC
GTGGTGCTGTCCAAGGCCGTGTGGGTGGTGGTGCTGAACAACCCGGCGCCCATCTTCCCCTACGAGCATCCGGCCCTGTT
CTCCATGACGCTGGCCTTCCTGGTCACCATCGTGGTCTCCAAGCTGGACGGCAGCGAAACCGCCAAGGCGGAGAAGGCTC
TGTTCGACGACCAGTATGTCCGCGCCCAGACGGGAATCGGTGCGGCCAGCGCCTCGAATCATTAA

Upstream 100 bases:

>100_bases
TCATCGTGGTGTCTTGGCTGCTGACCGGGCTGTACTCGCACTTCGCCAACGGCGAGTTCGAGGAGCTGAACAAGGACGTG
GTGCGCGAGGTGCTGGAATA

Downstream 100 bases:

>100_bases
TGGTCCGATCCGGCCGGCGACATCGTCGGCCGGTGAATCGGCCCATCAAACTCACTAGTTACCTCCCGCAAACTGCGAGC
CCCGCCGGAGTTCTTCTCCG

Product: acetate permease

Products: NA

Alternate protein names: Acetate permease; Acetate transporter ActP [H]

Number of amino acids: Translated: 554; Mature: 554

Protein sequence:

>554_residues
MKRILPILLALAVPTAALAGPGDLGGSEKQPINVTAIAMFFAFVMGTLGITYWASKRTKSASDFYTAGGGITGFQNGLAI
AGDYMSAATLLGLSSMVFATGFDGFIYTISFFVGWPIILFLLAERLRNLGRYTFADIASYRLDQSKVRTFAAMGSLTVVC
FYLIVQMVGAGQLIKLLFGLDYAVAVIIVGVLMVVYVTFGGMIATTWVQIIKACLLLGGGVLLCALALSKFGFSLENVAA
KAVESHKAGVKIMGPGTMLADPVSAVSLSLGLVFGTAALPHILMRFFTVPNAKEARKSVFVASGFIGFFFLIVCILGLAA
VSIVGTDPQFFEGGKVGGKLLGGGNMPVMHLAKALGGDIFLGFLSAVAFATILAVVSGLALAGASAIAHDIYARVIRKGH
ATEAEEMRVSKLSSLVLGVVAVILGIMFEKQNVAFLVGLTFGIAASANFPVLFLSMYWRGLTTKGALWGGIAGLVSAVTC
VVLSKAVWVVVLNNPAPIFPYEHPALFSMTLAFLVTIVVSKLDGSETAKAEKALFDDQYVRAQTGIGAASASNH

Sequences:

>Translated_554_residues
MKRILPILLALAVPTAALAGPGDLGGSEKQPINVTAIAMFFAFVMGTLGITYWASKRTKSASDFYTAGGGITGFQNGLAI
AGDYMSAATLLGLSSMVFATGFDGFIYTISFFVGWPIILFLLAERLRNLGRYTFADIASYRLDQSKVRTFAAMGSLTVVC
FYLIVQMVGAGQLIKLLFGLDYAVAVIIVGVLMVVYVTFGGMIATTWVQIIKACLLLGGGVLLCALALSKFGFSLENVAA
KAVESHKAGVKIMGPGTMLADPVSAVSLSLGLVFGTAALPHILMRFFTVPNAKEARKSVFVASGFIGFFFLIVCILGLAA
VSIVGTDPQFFEGGKVGGKLLGGGNMPVMHLAKALGGDIFLGFLSAVAFATILAVVSGLALAGASAIAHDIYARVIRKGH
ATEAEEMRVSKLSSLVLGVVAVILGIMFEKQNVAFLVGLTFGIAASANFPVLFLSMYWRGLTTKGALWGGIAGLVSAVTC
VVLSKAVWVVVLNNPAPIFPYEHPALFSMTLAFLVTIVVSKLDGSETAKAEKALFDDQYVRAQTGIGAASASNH
>Mature_554_residues
MKRILPILLALAVPTAALAGPGDLGGSEKQPINVTAIAMFFAFVMGTLGITYWASKRTKSASDFYTAGGGITGFQNGLAI
AGDYMSAATLLGLSSMVFATGFDGFIYTISFFVGWPIILFLLAERLRNLGRYTFADIASYRLDQSKVRTFAAMGSLTVVC
FYLIVQMVGAGQLIKLLFGLDYAVAVIIVGVLMVVYVTFGGMIATTWVQIIKACLLLGGGVLLCALALSKFGFSLENVAA
KAVESHKAGVKIMGPGTMLADPVSAVSLSLGLVFGTAALPHILMRFFTVPNAKEARKSVFVASGFIGFFFLIVCILGLAA
VSIVGTDPQFFEGGKVGGKLLGGGNMPVMHLAKALGGDIFLGFLSAVAFATILAVVSGLALAGASAIAHDIYARVIRKGH
ATEAEEMRVSKLSSLVLGVVAVILGIMFEKQNVAFLVGLTFGIAASANFPVLFLSMYWRGLTTKGALWGGIAGLVSAVTC
VVLSKAVWVVVLNNPAPIFPYEHPALFSMTLAFLVTIVVSKLDGSETAKAEKALFDDQYVRAQTGIGAASASNH

Specific function: Transports acetate [H]

COG id: COG4147

COG function: function code R; Predicted symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI310128183, Length=534, Percent_Identity=24.5318352059925, Blast_Score=92, Evalue=1e-18,
Organism=Escherichia coli, GI1790503, Length=554, Percent_Identity=59.2057761732852, Blast_Score=662, Evalue=0.0,
Organism=Escherichia coli, GI1787251, Length=468, Percent_Identity=27.1367521367521, Blast_Score=99, Evalue=8e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014083
- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 58035; Mature: 58035

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: PS00456 NA_SOLUT_SYMP_1 ; PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRILPILLALAVPTAALAGPGDLGGSEKQPINVTAIAMFFAFVMGTLGITYWASKRTKS
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
ASDFYTAGGGITGFQNGLAIAGDYMSAATLLGLSSMVFATGFDGFIYTISFFVGWPIILF
CCCCEECCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
LLAERLRNLGRYTFADIASYRLDQSKVRTFAAMGSLTVVCFYLIVQMVGAGQLIKLLFGL
HHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
DYAVAVIIVGVLMVVYVTFGGMIATTWVQIIKACLLLGGGVLLCALALSKFGFSLENVAA
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHH
KAVESHKAGVKIMGPGTMLADPVSAVSLSLGLVFGTAALPHILMRFFTVPNAKEARKSVF
HHHHHHCCCEEEECCCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
VASGFIGFFFLIVCILGLAAVSIVGTDPQFFEGGKVGGKLLGGGNMPVMHLAKALGGDIF
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHCHHHH
LGFLSAVAFATILAVVSGLALAGASAIAHDIYARVIRKGHATEAEEMRVSKLSSLVLGVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
AVILGIMFEKQNVAFLVGLTFGIAASANFPVLFLSMYWRGLTTKGALWGGIAGLVSAVTC
HHHHHHHHCCCCCEEEEEHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
VVLSKAVWVVVLNNPAPIFPYEHPALFSMTLAFLVTIVVSKLDGSETAKAEKALFDDQYV
HHHHHHHEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCHHHH
RAQTGIGAASASNH
HHHCCCCCCCCCCC
>Mature Secondary Structure
MKRILPILLALAVPTAALAGPGDLGGSEKQPINVTAIAMFFAFVMGTLGITYWASKRTKS
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
ASDFYTAGGGITGFQNGLAIAGDYMSAATLLGLSSMVFATGFDGFIYTISFFVGWPIILF
CCCCEECCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
LLAERLRNLGRYTFADIASYRLDQSKVRTFAAMGSLTVVCFYLIVQMVGAGQLIKLLFGL
HHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
DYAVAVIIVGVLMVVYVTFGGMIATTWVQIIKACLLLGGGVLLCALALSKFGFSLENVAA
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHH
KAVESHKAGVKIMGPGTMLADPVSAVSLSLGLVFGTAALPHILMRFFTVPNAKEARKSVF
HHHHHHCCCEEEECCCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
VASGFIGFFFLIVCILGLAAVSIVGTDPQFFEGGKVGGKLLGGGNMPVMHLAKALGGDIF
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHCHHHH
LGFLSAVAFATILAVVSGLALAGASAIAHDIYARVIRKGHATEAEEMRVSKLSSLVLGVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
AVILGIMFEKQNVAFLVGLTFGIAASANFPVLFLSMYWRGLTTKGALWGGIAGLVSAVTC
HHHHHHHHCCCCCEEEEEHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
VVLSKAVWVVVLNNPAPIFPYEHPALFSMTLAFLVTIVVSKLDGSETAKAEKALFDDQYV
HHHHHHHEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCHHHH
RAQTGIGAASASNH
HHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA