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The map label for this gene is mmgC [H]

Identifier: 83311687

GI number: 83311687

Start: 2774087

End: 2775271

Strand: Reverse

Name: mmgC [H]

Synonym: amb2588

Alternate gene names: 83311687

Gene position: 2775271-2774087 (Counterclockwise)

Preceding gene: 83311688

Following gene: 83311686

Centisome position: 55.87

GC content: 67.17

Gene sequence:

>1185_bases
ATGAGTGACGCCACGTTTCTCGACTGGCCCTTTCTCGACGAGTCCCACCGCGCCTTTGCCCGGTCGCTCGAGGACTGGGC
CGGCACCATCCTCCCAGGGGTGTGCCCCGAGGACGAGGCGCACGGCCCCGCCATGGACCAGACCGCCCGACGCCTGGTAA
CGGCCTTGGGACAGGCGGGGTTCCTTAAAGCGGCCATTCCGGCCGCCTATGGCGGGCGGGCAAAAGATTTCGACGTGCGG
GCGCTGTGCCTGGGACGGGAAATCCTCGCCCGCCACGCCGGTCTTGCCGATTTCGCCTTCGCCATGCAGGGTCTGGGCAG
CGCCGCCATCACTCTGTTCGGCAATGCCGAGCAGCAGGCCCGCTACCTGCCCAAGGTGGGCACCGGCGAGATGATCGCCG
CCTTCGCCATTTCCGAGGCCGATGCCGGGTCGGATGTGGGCGCCATGACCACCAAGGCGGTCCTGGACGGCGACCACTAT
GTCATCGACGGCGCCAAGACCTGGATTTCCAATGCCGGGCTGGCGGACTTCTACACCGTCTTCGCTCGAATCGGCGACGG
GGAGGGGGCCAAGGGACTCGCTGCATTCGTGGTTGACGCCCGGACGCCCGGACTTTCGGTGTCGGAGCGAATCGATGTCA
TGGCGCCCCATCCCCTGGGATCGTTGCGCTTTGACAACATGCGGGTGCCGGCCGCCAACCTGTTGGGCAAGCCCGGCGAT
GGCTTCAAGGTGGCCATGAGCGTGCTGGACGTCTTCCGCACCACGGTGGGTGCCGCCGCCTTGGGCTTTGCGCGGCGCGC
CATGGACGAGGCGGTGTCGCGCTCGGTCAAGCGCAAGGCCTTCGGCTCGCGCCTCGCCGACTTCCAGCTGATCCAGGCCA
AGATCGCCGACATGGCGGTGGCCGTCGACACCTCGGCCCTGCTGATCTACCGCTCGGCCTGGGTCAAGGACACCAAGGGC
GGCCGGGTGACCCGCGAAGCCTCCATGGCCAAGCTGTGGGCCACCGAGCAGGCCCAGATGGTCATCGATCAGGCGGTGCA
GATCTGGGGCGGCCTGGGGGTGATCAGCGGCATGGCGGTGGAGCAGCTCTATCGCGAGATCCGGGCGCTGCGCATCTACG
AGGGCACCAGCGAGATCCAGAAGCTGGTGATCGCCTCCAAGGTCTATGAAGGGCTGACCCTATGA

Upstream 100 bases:

>100_bases
CGCCTTCGCCAACAAGCAGGCGCCGGTGTTCGAAGGCAACTGATCTCGGCTTTGCCCCCCTCTCCCGCAAGCGGGAGAGG
GGCTAAAAAGGAAAAGTATC

Downstream 100 bases:

>100_bases
TGGGAGATCCCTGGCCGCTTGCCGGCCGTCATGCCCTGGTCACCGGCGGCGGGCGCGGCATCGGTGCCGCCATCGCCCGC
CAGATGCTGGCGCTCGGCGC

Product: Acyl-CoA dehydrogenase

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 394; Mature: 393

Protein sequence:

>394_residues
MSDATFLDWPFLDESHRAFARSLEDWAGTILPGVCPEDEAHGPAMDQTARRLVTALGQAGFLKAAIPAAYGGRAKDFDVR
ALCLGREILARHAGLADFAFAMQGLGSAAITLFGNAEQQARYLPKVGTGEMIAAFAISEADAGSDVGAMTTKAVLDGDHY
VIDGAKTWISNAGLADFYTVFARIGDGEGAKGLAAFVVDARTPGLSVSERIDVMAPHPLGSLRFDNMRVPAANLLGKPGD
GFKVAMSVLDVFRTTVGAAALGFARRAMDEAVSRSVKRKAFGSRLADFQLIQAKIADMAVAVDTSALLIYRSAWVKDTKG
GRVTREASMAKLWATEQAQMVIDQAVQIWGGLGVISGMAVEQLYREIRALRIYEGTSEIQKLVIASKVYEGLTL

Sequences:

>Translated_394_residues
MSDATFLDWPFLDESHRAFARSLEDWAGTILPGVCPEDEAHGPAMDQTARRLVTALGQAGFLKAAIPAAYGGRAKDFDVR
ALCLGREILARHAGLADFAFAMQGLGSAAITLFGNAEQQARYLPKVGTGEMIAAFAISEADAGSDVGAMTTKAVLDGDHY
VIDGAKTWISNAGLADFYTVFARIGDGEGAKGLAAFVVDARTPGLSVSERIDVMAPHPLGSLRFDNMRVPAANLLGKPGD
GFKVAMSVLDVFRTTVGAAALGFARRAMDEAVSRSVKRKAFGSRLADFQLIQAKIADMAVAVDTSALLIYRSAWVKDTKG
GRVTREASMAKLWATEQAQMVIDQAVQIWGGLGVISGMAVEQLYREIRALRIYEGTSEIQKLVIASKVYEGLTL
>Mature_393_residues
SDATFLDWPFLDESHRAFARSLEDWAGTILPGVCPEDEAHGPAMDQTARRLVTALGQAGFLKAAIPAAYGGRAKDFDVRA
LCLGREILARHAGLADFAFAMQGLGSAAITLFGNAEQQARYLPKVGTGEMIAAFAISEADAGSDVGAMTTKAVLDGDHYV
IDGAKTWISNAGLADFYTVFARIGDGEGAKGLAAFVVDARTPGLSVSERIDVMAPHPLGSLRFDNMRVPAANLLGKPGDG
FKVAMSVLDVFRTTVGAAALGFARRAMDEAVSRSVKRKAFGSRLADFQLIQAKIADMAVAVDTSALLIYRSAWVKDTKGG
RVTREASMAKLWATEQAQMVIDQAVQIWGGLGVISGMAVEQLYREIRALRIYEGTSEIQKLVIASKVYEGLTL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=381, Percent_Identity=37.5328083989501, Blast_Score=226, Evalue=2e-59,
Organism=Homo sapiens, GI21361497, Length=356, Percent_Identity=34.2696629213483, Blast_Score=198, Evalue=7e-51,
Organism=Homo sapiens, GI187960098, Length=332, Percent_Identity=37.0481927710843, Blast_Score=196, Evalue=2e-50,
Organism=Homo sapiens, GI4557231, Length=334, Percent_Identity=36.8263473053892, Blast_Score=196, Evalue=2e-50,
Organism=Homo sapiens, GI4501859, Length=354, Percent_Identity=34.180790960452, Blast_Score=192, Evalue=5e-49,
Organism=Homo sapiens, GI76496475, Length=400, Percent_Identity=32, Blast_Score=188, Evalue=7e-48,
Organism=Homo sapiens, GI4557235, Length=400, Percent_Identity=32, Blast_Score=188, Evalue=8e-48,
Organism=Homo sapiens, GI226958414, Length=354, Percent_Identity=31.9209039548023, Blast_Score=179, Evalue=4e-45,
Organism=Homo sapiens, GI226958412, Length=343, Percent_Identity=32.3615160349854, Blast_Score=177, Evalue=1e-44,
Organism=Homo sapiens, GI7656849, Length=283, Percent_Identity=33.5689045936396, Blast_Score=171, Evalue=2e-42,
Organism=Homo sapiens, GI4501857, Length=349, Percent_Identity=28.080229226361, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI4503943, Length=345, Percent_Identity=27.2463768115942, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI48976061, Length=284, Percent_Identity=29.9295774647887, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI211971008, Length=284, Percent_Identity=29.9295774647887, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI38505218, Length=290, Percent_Identity=27.9310344827586, Blast_Score=109, Evalue=6e-24,
Organism=Homo sapiens, GI7669494, Length=331, Percent_Identity=27.190332326284, Blast_Score=102, Evalue=4e-22,
Organism=Escherichia coli, GI87081958, Length=343, Percent_Identity=29.4460641399417, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1786223, Length=347, Percent_Identity=27.3775216138329, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI87082384, Length=261, Percent_Identity=24.1379310344828, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87081702, Length=269, Percent_Identity=26.0223048327138, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17534899, Length=341, Percent_Identity=37.2434017595308, Blast_Score=217, Evalue=7e-57,
Organism=Caenorhabditis elegans, GI17508101, Length=344, Percent_Identity=36.3372093023256, Blast_Score=210, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI17569725, Length=331, Percent_Identity=37.4622356495468, Blast_Score=207, Evalue=5e-54,
Organism=Caenorhabditis elegans, GI17570075, Length=334, Percent_Identity=38.3233532934132, Blast_Score=205, Evalue=3e-53,
Organism=Caenorhabditis elegans, GI17506239, Length=330, Percent_Identity=34.2424242424242, Blast_Score=192, Evalue=3e-49,
Organism=Caenorhabditis elegans, GI71985184, Length=293, Percent_Identity=35.4948805460751, Blast_Score=187, Evalue=9e-48,
Organism=Caenorhabditis elegans, GI17538396, Length=332, Percent_Identity=34.6385542168675, Blast_Score=184, Evalue=6e-47,
Organism=Caenorhabditis elegans, GI17533517, Length=276, Percent_Identity=35.1449275362319, Blast_Score=173, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI71990804, Length=298, Percent_Identity=33.5570469798658, Blast_Score=162, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI71985192, Length=240, Percent_Identity=35, Blast_Score=144, Evalue=7e-35,
Organism=Caenorhabditis elegans, GI32563615, Length=228, Percent_Identity=33.7719298245614, Blast_Score=139, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17551932, Length=376, Percent_Identity=27.3936170212766, Blast_Score=137, Evalue=9e-33,
Organism=Caenorhabditis elegans, GI17505929, Length=380, Percent_Identity=28.1578947368421, Blast_Score=134, Evalue=7e-32,
Organism=Caenorhabditis elegans, GI71982178, Length=283, Percent_Identity=32.5088339222615, Blast_Score=133, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17531909, Length=240, Percent_Identity=31.6666666666667, Blast_Score=118, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI17534353, Length=342, Percent_Identity=26.3157894736842, Blast_Score=114, Evalue=9e-26,
Organism=Caenorhabditis elegans, GI17562446, Length=333, Percent_Identity=28.5285285285285, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI86563383, Length=280, Percent_Identity=27.8571428571429, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI86563381, Length=280, Percent_Identity=27.8571428571429, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17531913, Length=168, Percent_Identity=29.1666666666667, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17540912, Length=275, Percent_Identity=26.1818181818182, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21356377, Length=381, Percent_Identity=38.5826771653543, Blast_Score=243, Evalue=2e-64,
Organism=Drosophila melanogaster, GI24646207, Length=384, Percent_Identity=38.28125, Blast_Score=237, Evalue=9e-63,
Organism=Drosophila melanogaster, GI24660351, Length=338, Percent_Identity=38.7573964497041, Blast_Score=220, Evalue=2e-57,
Organism=Drosophila melanogaster, GI24666513, Length=393, Percent_Identity=33.587786259542, Blast_Score=197, Evalue=8e-51,
Organism=Drosophila melanogaster, GI281363737, Length=364, Percent_Identity=32.6923076923077, Blast_Score=195, Evalue=4e-50,
Organism=Drosophila melanogaster, GI21355753, Length=347, Percent_Identity=32.8530259365994, Blast_Score=168, Evalue=7e-42,
Organism=Drosophila melanogaster, GI19920834, Length=314, Percent_Identity=30.8917197452229, Blast_Score=119, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 42028; Mature: 41896

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: PS00072 ACYL_COA_DH_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDATFLDWPFLDESHRAFARSLEDWAGTILPGVCPEDEAHGPAMDQTARRLVTALGQAG
CCCCCEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
FLKAAIPAAYGGRAKDFDVRALCLGREILARHAGLADFAFAMQGLGSAAITLFGNAEQQA
CHHHHCCHHCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEEECCCHHHH
RYLPKVGTGEMIAAFAISEADAGSDVGAMTTKAVLDGDHYVIDGAKTWISNAGLADFYTV
HHCCCCCCCCEEEHEEECCCCCCCCCHHHHHHHEECCCEEEECCHHHHHCCCCHHHHHHH
FARIGDGEGAKGLAAFVVDARTPGLSVSERIDVMAPHPLGSLRFDNMRVPAANLLGKPGD
HHHHCCCCCCCCEEEEEEECCCCCCCHHHCCCEECCCCCCCCEECCCCCCHHHHCCCCCC
GFKVAMSVLDVFRTTVGAAALGFARRAMDEAVSRSVKRKAFGSRLADFQLIQAKIADMAV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVDTSALLIYRSAWVKDTKGGRVTREASMAKLWATEQAQMVIDQAVQIWGGLGVISGMAV
HCCCHHHEEEHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQLYREIRALRIYEGTSEIQKLVIASKVYEGLTL
HHHHHHHHHHHEECCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SDATFLDWPFLDESHRAFARSLEDWAGTILPGVCPEDEAHGPAMDQTARRLVTALGQAG
CCCCEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
FLKAAIPAAYGGRAKDFDVRALCLGREILARHAGLADFAFAMQGLGSAAITLFGNAEQQA
CHHHHCCHHCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEEECCCHHHH
RYLPKVGTGEMIAAFAISEADAGSDVGAMTTKAVLDGDHYVIDGAKTWISNAGLADFYTV
HHCCCCCCCCEEEHEEECCCCCCCCCHHHHHHHEECCCEEEECCHHHHHCCCCHHHHHHH
FARIGDGEGAKGLAAFVVDARTPGLSVSERIDVMAPHPLGSLRFDNMRVPAANLLGKPGD
HHHHCCCCCCCCEEEEEEECCCCCCCHHHCCCEECCCCCCCCEECCCCCCHHHHCCCCCC
GFKVAMSVLDVFRTTVGAAALGFARRAMDEAVSRSVKRKAFGSRLADFQLIQAKIADMAV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVDTSALLIYRSAWVKDTKGGRVTREASMAKLWATEQAQMVIDQAVQIWGGLGVISGMAV
HCCCHHHEEEHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQLYREIRALRIYEGTSEIQKLVIASKVYEGLTL
HHHHHHHHHHHEECCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]