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The map label for this gene is argE [H]

Identifier: 83311474

GI number: 83311474

Start: 2580022

End: 2581236

Strand: Reverse

Name: argE [H]

Synonym: amb2375

Alternate gene names: 83311474

Gene position: 2581236-2580022 (Counterclockwise)

Preceding gene: 83311478

Following gene: 83311462

Centisome position: 51.97

GC content: 62.22

Gene sequence:

>1215_bases
ATGATGGCCACTGCCCACAAAGCGTCCCAGAGCGAGAACGGTTCCTTGAGCCAACATACCAAAACGCCCCTGCCGGCCAG
CATCGAAACGATCGCCAAGCTGATCGCCATCGACACTACAAGTTACAAGACTAATTTACAGTTAATCGATCTGGTGGACA
AAATCCTTTCCGGTCTTGGGGCTTCTGTCCGTAGGACTTGGGACGAGTCCAAGAACAAAGCGAACATCTTCGCCACAATT
GGCCCCAGTGATGTTCCGGGAATTGTCCTGTCCGGGCATACGGATGTCGTTCCCGTCGACGGACAGGACTGGTCTAGAGA
CCCCTTCCACCTTGTCCAAGCCGACGGCAAATTGTATGGCCGCGGCACCGCCGACATGAAAAGCTTCATTGCCATCTGTC
TGGCCATGGCGCCTCAATTCGCCGCCGCGCCCCTGCGCATGCCGGTCCACTTCGCCTTTTCCTATGACGAAGAAGTGGGC
TGTGTCGGCGTCCGCCGGCTGATCGACGATCTCGCCCATCTGCCGGTGCGCCCGGCCCTTTGCATCGTCGGCGAGCCCAC
CGACATGAAGGCGGTGATCGGCCACAAGGGCAAGAAGAGTGTCCGTTGCCATGTGGAGGGCCACGAATGCCACTCGGCCC
TCAACCATCAGGGCGTCAACGCCATTGAGATCGCCGCCGAAATGGTTACCCGCCTGCGCGCCCTGCAGCGCCGCATCCGG
GAACAGGGGCCCTTCGACCTTGGCTATCAGCCGCCCTATACCACCGTTCATACCGGCACCATGCAGGGGGGCACGGCGCT
GAACATCGTGCCGAAATCATGCTCCTTCGAGTTCGAGATTCGCAATCTGCCCGATCACGACCCGGAGACCCTGATGGCCG
AGGTCCGGGGCTGGGCCCAGGATCTGGTGCCCGAGATGCTGGCGGTCAGCGAAGCCAGCGGCATCACCCTGGACGAGCAC
AACTCGACCCCCGGCCTCGGCATGGACGAAATGGATGCGGCGGTGCGTCTGGTCTGCGCCCTGTCGGGCGCCAATCAGAC
CAGCAAGGTGGCCTTCACCACCGAGGCCGGGCTGTTCCAACAGGCCGGCATTCCGGCGGTGGTGATCGGCCCCGGCAGCA
TCACCCAGGCCCACCGGCCCGACGAGTTCATCACCCTGGAGCAGGTGGCCCAGTGCGAGGATTTCCTGCGGCGCCTGCTG
GCGCATATGTGCTGA

Upstream 100 bases:

>100_bases
CGTCGGCAAGCGGGAGAATAGCGCCTCGGATCCGTAATAACCACAAGATATTGGTTATAATTTGTAGCGGAAGACTGGCC
TTCAGGCTGGGGCGCGCACT

Downstream 100 bases:

>100_bases
GAGGGCGCTACTCGATCACCGCCTGAAGCGAGGTCCAGGTTCCCGGGGTGGGCGCCAGGAGTAGACAGCCCTCTTCCGCC
CTGGGGCGGTAGGGGCGGCC

Product: acetylornithine deacetylase/succinyl-diaminopimelate desuccinylase-like protein

Products: NA

Alternate protein names: AO; Acetylornithinase; N-acetylornithinase; NAO [H]

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MMATAHKASQSENGSLSQHTKTPLPASIETIAKLIAIDTTSYKTNLQLIDLVDKILSGLGASVRRTWDESKNKANIFATI
GPSDVPGIVLSGHTDVVPVDGQDWSRDPFHLVQADGKLYGRGTADMKSFIAICLAMAPQFAAAPLRMPVHFAFSYDEEVG
CVGVRRLIDDLAHLPVRPALCIVGEPTDMKAVIGHKGKKSVRCHVEGHECHSALNHQGVNAIEIAAEMVTRLRALQRRIR
EQGPFDLGYQPPYTTVHTGTMQGGTALNIVPKSCSFEFEIRNLPDHDPETLMAEVRGWAQDLVPEMLAVSEASGITLDEH
NSTPGLGMDEMDAAVRLVCALSGANQTSKVAFTTEAGLFQQAGIPAVVIGPGSITQAHRPDEFITLEQVAQCEDFLRRLL
AHMC

Sequences:

>Translated_404_residues
MMATAHKASQSENGSLSQHTKTPLPASIETIAKLIAIDTTSYKTNLQLIDLVDKILSGLGASVRRTWDESKNKANIFATI
GPSDVPGIVLSGHTDVVPVDGQDWSRDPFHLVQADGKLYGRGTADMKSFIAICLAMAPQFAAAPLRMPVHFAFSYDEEVG
CVGVRRLIDDLAHLPVRPALCIVGEPTDMKAVIGHKGKKSVRCHVEGHECHSALNHQGVNAIEIAAEMVTRLRALQRRIR
EQGPFDLGYQPPYTTVHTGTMQGGTALNIVPKSCSFEFEIRNLPDHDPETLMAEVRGWAQDLVPEMLAVSEASGITLDEH
NSTPGLGMDEMDAAVRLVCALSGANQTSKVAFTTEAGLFQQAGIPAVVIGPGSITQAHRPDEFITLEQVAQCEDFLRRLL
AHMC
>Mature_404_residues
MMATAHKASQSENGSLSQHTKTPLPASIETIAKLIAIDTTSYKTNLQLIDLVDKILSGLGASVRRTWDESKNKANIFATI
GPSDVPGIVLSGHTDVVPVDGQDWSRDPFHLVQADGKLYGRGTADMKSFIAICLAMAPQFAAAPLRMPVHFAFSYDEEVG
CVGVRRLIDDLAHLPVRPALCIVGEPTDMKAVIGHKGKKSVRCHVEGHECHSALNHQGVNAIEIAAEMVTRLRALQRRIR
EQGPFDLGYQPPYTTVHTGTMQGGTALNIVPKSCSFEFEIRNLPDHDPETLMAEVRGWAQDLVPEMLAVSEASGITLDEH
NSTPGLGMDEMDAAVRLVCALSGANQTSKVAFTTEAGLFQQAGIPAVVIGPGSITQAHRPDEFITLEQVAQCEDFLRRLL
AHMC

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. ArgE subfamily [H]

Homologues:

Organism=Homo sapiens, GI4501901, Length=335, Percent_Identity=25.3731343283582, Blast_Score=78, Evalue=2e-14,
Organism=Escherichia coli, GI1790395, Length=394, Percent_Identity=34.2639593908629, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI1788816, Length=259, Percent_Identity=28.1853281853282, Blast_Score=83, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71982085, Length=269, Percent_Identity=26.7657992565056, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71982082, Length=360, Percent_Identity=24.4444444444444, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21356353, Length=341, Percent_Identity=24.0469208211144, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24649206, Length=337, Percent_Identity=22.8486646884273, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010169
- InterPro:   IPR001261
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.16 [H]

Molecular weight: Translated: 43716; Mature: 43716

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: PS00759 ARGE_DAPE_CPG2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMATAHKASQSENGSLSQHTKTPLPASIETIAKLIAIDTTSYKTNLQLIDLVDKILSGLG
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCC
ASVRRTWDESKNKANIFATIGPSDVPGIVLSGHTDVVPVDGQDWSRDPFHLVQADGKLYG
HHHHHHHHCCCCCEEEEEEECCCCCCCEEEECCCCEEECCCCCCCCCCCEEEEECCEEEE
RGTADMKSFIAICLAMAPQFAAAPLRMPVHFAFSYDEEVGCVGVRRLIDDLAHLPVRPAL
CCCHHHHHHHHHHHHHCCHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCEE
CIVGEPTDMKAVIGHKGKKSVRCHVEGHECHSALNHQGVNAIEIAAEMVTRLRALQRRIR
EEEECCCCCHHHHCCCCCCCEEEEECCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
EQGPFDLGYQPPYTTVHTGTMQGGTALNIVPKSCSFEFEIRNLPDHDPETLMAEVRGWAQ
HCCCCCCCCCCCCCEEECCCCCCCEEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHH
DLVPEMLAVSEASGITLDEHNSTPGLGMDEMDAAVRLVCALSGANQTSKVAFTTEAGLFQ
HHHHHHHHHHCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHH
QAGIPAVVIGPGSITQAHRPDEFITLEQVAQCEDFLRRLLAHMC
HCCCCEEEECCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MMATAHKASQSENGSLSQHTKTPLPASIETIAKLIAIDTTSYKTNLQLIDLVDKILSGLG
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCC
ASVRRTWDESKNKANIFATIGPSDVPGIVLSGHTDVVPVDGQDWSRDPFHLVQADGKLYG
HHHHHHHHCCCCCEEEEEEECCCCCCCEEEECCCCEEECCCCCCCCCCCEEEEECCEEEE
RGTADMKSFIAICLAMAPQFAAAPLRMPVHFAFSYDEEVGCVGVRRLIDDLAHLPVRPAL
CCCHHHHHHHHHHHHHCCHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCEE
CIVGEPTDMKAVIGHKGKKSVRCHVEGHECHSALNHQGVNAIEIAAEMVTRLRALQRRIR
EEEECCCCCHHHHCCCCCCCEEEEECCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
EQGPFDLGYQPPYTTVHTGTMQGGTALNIVPKSCSFEFEIRNLPDHDPETLMAEVRGWAQ
HCCCCCCCCCCCCCEEECCCCCCCEEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHH
DLVPEMLAVSEASGITLDEHNSTPGLGMDEMDAAVRLVCALSGANQTSKVAFTTEAGLFQ
HHHHHHHHHHCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHH
QAGIPAVVIGPGSITQAHRPDEFITLEQVAQCEDFLRRLLAHMC
HCCCCEEEECCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA