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The map label for this gene is senX3 [H]

Identifier: 83311278

GI number: 83311278

Start: 2360324

End: 2361823

Strand: Reverse

Name: senX3 [H]

Synonym: amb2179

Alternate gene names: 83311278

Gene position: 2361823-2360324 (Counterclockwise)

Preceding gene: 83311279

Following gene: 83311275

Centisome position: 47.55

GC content: 64.87

Gene sequence:

>1500_bases
ATGGTTTGTCCCAGCGATCCCAAACGAAAAGCCCTCAGCCCCCTGGGCCGGCGGATCGTCATCTATACCGTAGTCTTCAG
TTCGGTGGTCACCCTGATCATCAGCATTCTTCAGCTGGTCAACGAGTTCACCCAGCGGGAATCCATGGTGCGGGCGCAGT
TGGACAGCGTCGATGTCTTGTTGCCCTCCATCGCCGAAAGCGTCTGGACCTTCAACGAGTCCCAGATCAGCTTGGCATTG
CAGGCCCTGACCAGCATGCCGAACATGGAGAAGGCGACCATCACCACCGCGGAAGGTCGGATATGGTCCCGAGGCCGGGA
GACCTCCACCCACACCATCGCCAGGACGTTCACGCTGGAGCGCCAGACCAGCAGGGGGCGGGAAGCCCTTGGCACGCTGG
ACCTTCTCGCGGGCACGGATGCCGTCTATCTGGCGGTACTCACCCTGACGGCGGAAATTCTGTTCGGAAACGCCATCAAG
ACTCTCATGGTGGCGGGTTTCATGGGCTGGCTGATTCACAGGCTGGTCATCAGCCGCCTGCCCCCGCTCAAGCGGGAAGT
GGAAGCCTTGCTGGACGGCCTTGACCCGCCCATCGGCGGCGGGCCGGCGGAGACGGCCGCCAACCGCCCTTCCGGGGACG
AAATCGACATCCTGCGAGGCAGCTTCGCCTGCATGGCGGCGCGGTTGAACGACGCCCTCGGCACCATGCGGAAGGCCAAG
GACGAACTGCACCAGGCCAACCAGGCGCTGGACTCCCGCGTGCGGGACAAGACCGCCCAGTTGGAGGAAAGCAAGAAGGT
CGCCGAAGAGGCCGCCGAGGCCGCCCTGCGTGCCATGGGGGAGCAACGCAACTTCCTCTCCATGGTCTCCCACGAGTTCC
GGGGGCCTCTTTCCACCATCACCGGGGCGGCCCAGTTGATCGCCATATATGGCGGCGGGCATTCCGAGCTGGCCGACGAG
GTCGCCAAGATCCATCGCGCCCTGGGCCGGATGTCGAACCTGATCAACGAATACCTCAACGAGGAGCGCCTGGACTCGGC
GGCAAGCCCTCTGGACGCGGCGCGCTTCGACCTGGGCGGGATGGTCGAGGACGCCTGCGCGTCCGGCCTGTTCTCGACCA
ACGATCGGCCCCTGGACGTCTCGACCGAACCCGGAGTGTTCGTGTTCGGCGACAGCGCCCTGATGTCCATCGCCGTTTCA
AACATCGCCGACAACGCGCTGAAATTCTCGCCCGCCGACAGTCCGGTCACGGTCACCCTGAGGCGACGGGACGGCTTTGC
CGCCGTGACGGTTCGCGACCATGGTCCGGGAATTCCTCCCGACGAACAGGAGCGGATCTTCGAGAAGTACTACCGTTCGA
TCCGGACCGACCGGGTCTGTGGCGTCGGCCTCGGGCTGTATCTGGTCAAGCGGATCGTCGACCTGCATGGCGGCACCATC
GCCATCGACAGCCCGCCCTCCGGCGGCACGGCCTTTACCGTGAGCCTGCCCCTGGCCTGA

Upstream 100 bases:

>100_bases
TTTTTTCACGTTTGAGGACTGGGCGGGGTAACGCCAACTCTGGTATATATCTTTAGAGTTAATTTTCTTTGGTCTTCACG
ATCAAGGGCTCCTTTTGACG

Downstream 100 bases:

>100_bases
GCGGCTCTCCCCCCGAATCAGGGAATCTCGGAATCCGAGGCCGAGAGCATCGGCGGGGCCTTGGCGCCGTCGGGCAGAGG
CCGGTCGTCGCCGCCCAAGG

Product: Signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 499; Mature: 499

Protein sequence:

>499_residues
MVCPSDPKRKALSPLGRRIVIYTVVFSSVVTLIISILQLVNEFTQRESMVRAQLDSVDVLLPSIAESVWTFNESQISLAL
QALTSMPNMEKATITTAEGRIWSRGRETSTHTIARTFTLERQTSRGREALGTLDLLAGTDAVYLAVLTLTAEILFGNAIK
TLMVAGFMGWLIHRLVISRLPPLKREVEALLDGLDPPIGGGPAETAANRPSGDEIDILRGSFACMAARLNDALGTMRKAK
DELHQANQALDSRVRDKTAQLEESKKVAEEAAEAALRAMGEQRNFLSMVSHEFRGPLSTITGAAQLIAIYGGGHSELADE
VAKIHRALGRMSNLINEYLNEERLDSAASPLDAARFDLGGMVEDACASGLFSTNDRPLDVSTEPGVFVFGDSALMSIAVS
NIADNALKFSPADSPVTVTLRRRDGFAAVTVRDHGPGIPPDEQERIFEKYYRSIRTDRVCGVGLGLYLVKRIVDLHGGTI
AIDSPPSGGTAFTVSLPLA

Sequences:

>Translated_499_residues
MVCPSDPKRKALSPLGRRIVIYTVVFSSVVTLIISILQLVNEFTQRESMVRAQLDSVDVLLPSIAESVWTFNESQISLAL
QALTSMPNMEKATITTAEGRIWSRGRETSTHTIARTFTLERQTSRGREALGTLDLLAGTDAVYLAVLTLTAEILFGNAIK
TLMVAGFMGWLIHRLVISRLPPLKREVEALLDGLDPPIGGGPAETAANRPSGDEIDILRGSFACMAARLNDALGTMRKAK
DELHQANQALDSRVRDKTAQLEESKKVAEEAAEAALRAMGEQRNFLSMVSHEFRGPLSTITGAAQLIAIYGGGHSELADE
VAKIHRALGRMSNLINEYLNEERLDSAASPLDAARFDLGGMVEDACASGLFSTNDRPLDVSTEPGVFVFGDSALMSIAVS
NIADNALKFSPADSPVTVTLRRRDGFAAVTVRDHGPGIPPDEQERIFEKYYRSIRTDRVCGVGLGLYLVKRIVDLHGGTI
AIDSPPSGGTAFTVSLPLA
>Mature_499_residues
MVCPSDPKRKALSPLGRRIVIYTVVFSSVVTLIISILQLVNEFTQRESMVRAQLDSVDVLLPSIAESVWTFNESQISLAL
QALTSMPNMEKATITTAEGRIWSRGRETSTHTIARTFTLERQTSRGREALGTLDLLAGTDAVYLAVLTLTAEILFGNAIK
TLMVAGFMGWLIHRLVISRLPPLKREVEALLDGLDPPIGGGPAETAANRPSGDEIDILRGSFACMAARLNDALGTMRKAK
DELHQANQALDSRVRDKTAQLEESKKVAEEAAEAALRAMGEQRNFLSMVSHEFRGPLSTITGAAQLIAIYGGGHSELADE
VAKIHRALGRMSNLINEYLNEERLDSAASPLDAARFDLGGMVEDACASGLFSTNDRPLDVSTEPGVFVFGDSALMSIAVS
NIADNALKFSPADSPVTVTLRRRDGFAAVTVRDHGPGIPPDEQERIFEKYYRSIRTDRVCGVGLGLYLVKRIVDLHGGTI
AIDSPPSGGTAFTVSLPLA

Specific function: Part of the two-component regulatory system senX3/regX3. Phosphorylates regX3 under conditions of phosphate limitation. Probably does not itself sense phosphate concentrations, which may be relayed to senX3 by the pstSCAB phosphate transporter system [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786912, Length=238, Percent_Identity=30.672268907563, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI1788393, Length=221, Percent_Identity=28.9592760180996, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1786600, Length=230, Percent_Identity=29.5652173913043, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI145693157, Length=256, Percent_Identity=29.6875, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1788713, Length=238, Percent_Identity=26.890756302521, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1790346, Length=268, Percent_Identity=26.4925373134328, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1789149, Length=301, Percent_Identity=25.2491694352159, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1789403, Length=220, Percent_Identity=30, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI48994928, Length=236, Percent_Identity=27.5423728813559, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI87081816, Length=324, Percent_Identity=26.5432098765432, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1786783, Length=256, Percent_Identity=25.78125, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1787894, Length=253, Percent_Identity=27.2727272727273, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1790436, Length=217, Percent_Identity=29.4930875576037, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1788279, Length=213, Percent_Identity=25.3521126760563, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790861, Length=239, Percent_Identity=25.5230125523013, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1789808, Length=227, Percent_Identity=25.5506607929515, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1790551, Length=226, Percent_Identity=26.1061946902655, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1788549, Length=252, Percent_Identity=27.3809523809524, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1790567, Length=107, Percent_Identity=37.3831775700935, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 53916; Mature: 53916

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVCPSDPKRKALSPLGRRIVIYTVVFSSVVTLIISILQLVNEFTQRESMVRAQLDSVDVL
CCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPSIAESVWTFNESQISLALQALTSMPNMEKATITTAEGRIWSRGRETSTHTIARTFTLE
HHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCEEEECCCCHHCCCCCCCHHHHHHHEEEH
RQTSRGREALGTLDLLAGTDAVYLAVLTLTAEILFGNAIKTLMVAGFMGWLIHRLVISRL
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PPLKREVEALLDGLDPPIGGGPAETAANRPSGDEIDILRGSFACMAARLNDALGTMRKAK
CCHHHHHHHHHHCCCCCCCCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
DELHQANQALDSRVRDKTAQLEESKKVAEEAAEAALRAMGEQRNFLSMVSHEFRGPLSTI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
TGAAQLIAIYGGGHSELADEVAKIHRALGRMSNLINEYLNEERLDSAASPLDAARFDLGG
HHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCHHHHHCCCC
MVEDACASGLFSTNDRPLDVSTEPGVFVFGDSALMSIAVSNIADNALKFSPADSPVTVTL
HHHHHHHCCCCCCCCCCEECCCCCCEEEECCHHHHHHHHHHHHHCCEECCCCCCCEEEEE
RRRDGFAAVTVRDHGPGIPPDEQERIFEKYYRSIRTDRVCGVGLGLYLVKRIVDLHGGTI
EECCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEE
AIDSPPSGGTAFTVSLPLA
EECCCCCCCEEEEEEECCC
>Mature Secondary Structure
MVCPSDPKRKALSPLGRRIVIYTVVFSSVVTLIISILQLVNEFTQRESMVRAQLDSVDVL
CCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPSIAESVWTFNESQISLALQALTSMPNMEKATITTAEGRIWSRGRETSTHTIARTFTLE
HHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCEEEECCCCHHCCCCCCCHHHHHHHEEEH
RQTSRGREALGTLDLLAGTDAVYLAVLTLTAEILFGNAIKTLMVAGFMGWLIHRLVISRL
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PPLKREVEALLDGLDPPIGGGPAETAANRPSGDEIDILRGSFACMAARLNDALGTMRKAK
CCHHHHHHHHHHCCCCCCCCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
DELHQANQALDSRVRDKTAQLEESKKVAEEAAEAALRAMGEQRNFLSMVSHEFRGPLSTI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
TGAAQLIAIYGGGHSELADEVAKIHRALGRMSNLINEYLNEERLDSAASPLDAARFDLGG
HHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCHHHHHCCCC
MVEDACASGLFSTNDRPLDVSTEPGVFVFGDSALMSIAVSNIADNALKFSPADSPVTVTL
HHHHHHHCCCCCCCCCCEECCCCCCEEEECCHHHHHHHHHHHHHCCEECCCCCCCEEEEE
RRRDGFAAVTVRDHGPGIPPDEQERIFEKYYRSIRTDRVCGVGLGLYLVKRIVDLHGGTI
EECCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEE
AIDSPPSGGTAFTVSLPLA
EECCCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA