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The map label for this gene is lgrC [H]

Identifier: 83310458

GI number: 83310458

Start: 1471870

End: 1475058

Strand: Reverse

Name: lgrC [H]

Synonym: amb1359

Alternate gene names: 83310458

Gene position: 1475058-1471870 (Counterclockwise)

Preceding gene: 83310459

Following gene: 83310457

Centisome position: 29.7

GC content: 68.52

Gene sequence:

>3189_bases
GTGCCGACCCTGCTGAGCCTGCTGCCCGGCGACATTCCCGGCCTGCGGGTCATCATCCTGGGCGGCGAGGCCTGCCCCGC
GGCCCTGGCCGAGCGCTGGTGCCGGCCCGGACGGCGCATCTTCAATTCCTACGGCCCCACCGAGGCCACCGTGGTCGCCA
CCATGGCCGAGGTCGAGCCGGGCAAGCCGGTGACCATCGGGCGGCCCATCCCCAACTATGTCTGCCATGTGGTGGACGAT
TTCATCCAGCCGGTGGCCCCCGGCGCCACCGGCGAACTGCTGATCGGCGGGCCGGGCGTGGCGGCGGGCTATCTCGGCCG
CCCCGACCTCACCGCCGAGAAGTTCATCCCCAATCCCTGGGACACCGACGGCAGCGCCCCGGTGCTGTACCGCTCGGGCG
ACGCGGTGGCCATTGACGGCAACGGCGACATCACCTTCCACGGCCGCATCGACGATCAGGTCAAGATCCGCGGCTTCCGC
GTCGAGCTGGGCGAGATCGAAGCCCGCCTGGCGGCGCTTCCCGGCGTCAATCAGGCGGCGGTCAGCTTGCGCACCGACGA
CGGCATCGAGCGGCTGGTAGCGACCATCCTGCCCGAGGCCGGAGCCGTCATCGAGGGCGGCGCGTTGAAGGAGGGCCTGC
GCGCCCAGCTTCCCGCCTATATGGTTCCCTCCCATTATCTGGTGGTCGACGAGCTTCCCCGCCTGATTTCCGGCAAGCTG
AACCGCAAGGCGCTGAAGGACCTGCCGCTGGACCTTTCCGTCGGCGGCGGCGAGCAGGAGGAGCCGGCGACCACCACCGA
GGCCGCCCTGCTGGAGGCGGCGCGCCGGGTGTTCCCCGGTCAGGTCATTGCCTTCGAGGCCGATTTCTTCCTCGATCTCG
GCGGCCATTCGCTGCTGGCCGCCAAGTTCGTCTCGGCGGTGCGCGAGACGCCGGAACTGGCCAGCCTGACGCTCAACGAG
ATCTATTCCGCCCGCACGCTCCGGGCCATGGGAGCGCTGCTCGACCTGCGCGCCCCGGCCGCCGGGGCCAAGCCCGCCGA
CCTGTCCTTCGATCCGCCCACCCTGCGCCGCCGCTTCCTGTGCGGACTGGCCCAGGCGGTGGCCATGCCCTTCATCCTGG
CGCTGACCACGGCGCCGTGGCTGGGCGTGTTCATCTCCTACATGCTGCTGTCGGGCGAGGATGCCAGCTTCTTCACCGAG
ATGAGCACCCTGATGCTCACCTATGCGGTGATCAATGTGGGCACCATCTCGGCCTCCATCGCCCTCAAATGGGTGATCCT
GGGGCGGACCAAGCCCGGCCGCCACAAGCTGTGGGGACCCTATTACTTCCGCTGGTGGCTGGCCCAGCGCGTGGTCAGCG
TCGCCCATATCAAGTGGTTCCAGGGCACGCCGATCATGAGCATCTATCTGCGCCTGCTGGGCGCCAGGGTGGGCAGCGAC
TGCGTGCTGGCCGAGATGGAGGCCGGCGCCTTCGATCTGGTGACCATCGGCAACGGCGTGGCCATCGGCGGCAAGACCCG
GCTGGCCAATGCGGAAGCCGTGGGCGACGAACTGGTGATCGGCCCCATCGTGATCGGCGACGATGCCTATATCGGCACCT
CGTGCATGCTCAGCGACGGAGTGGTGATCGAGACGGGCGGCGAGGTCGGCGACCTCACCTCCATCGCCGCCGGCACCCGC
ATCGGCCGCTACGAGCATTGGGACGGCTCGCCCGGCCGCAAGGTGGGCATGGTCGACGAGGCCGCCCTGCCCGAGGCCGC
CCATGCCGGCTTCGGCCGCAAGCTGGCCCTGACCTGCCTCTACGGCCTGATGCTGGTAGTGCTGCCGCCCATCAGCCTGC
TGCCGATCTTCCCGGCCTTCTTCATCTTCGAGCGCCTCAGCGACTATTTCGCCGGCGGCGAATACGCCACCATCCTGCCG
CTGCTGGCCTGGCCCACCGCCATGGCGCTGATCGCCGTCACCGTGCTGCTGATCGCCGTGGTGCGCTGGTCGGTGCTGCC
GGTGGTCACCGCGGGCAGCTATTCCATCTATGGCGGCTTCTATGTCCGCAAATGGATCGTCGCCCTGGCCACCGAGCTGA
TGCTCGAGACCCTGTCGTCGCTCTACGCCACCGTCTATATGCGGCTGTGGTACCGGCTGATGGGCGCCAAGATCGGCAAG
GACGCCGAAATCTCGTGCAATCTGGCCGGACGCTACGACCTGACCGATATCGGGCCGGGCTGCTTCATCGCCGACGAGGT
GGTGCTGGGCGACGAATGCGTGCGCCGGGGCTGGATGGTGCTGGAGCCCGTGAAGACCGAGGCCCGCGTCTTCGTCGGCA
ACGACGCCGTGGTGCCGCCCGGCGCGGTGATTCCCACCGGCGCCCTGATCGGCATCAAGTCGCGGCCGCCGGCCAACGAG
CAGATGTCGCCGGGCGATACCTGGTTCGGCAATCCCCCCTTCAAGCTGCCGGTGCGCCAGCGCTTCGACGACGTGGGCGC
CGACTGGACCTTCGCGCCGCCCCTGTGGCGCCGGGTGTGGCGCGCCGTGTTCGAGGCCTTCGCCGTCTCGCTGCCCACCG
CTTTGTTCATCACCTTCGGCATCATGACCGTGGATCTGCTGGCGCCCAGCATCCTGGCCCGGGATTACGCCATCGTCCTG
CCGCTGTTCGTGGCCGCGTCGGTGGCCATCTCGTTCTCGCTGGCCCTGTCGTCGGTGGCGGTGAAGTGGCTGATGATGGG
CGTCTACCGTCCCACCGCCAAGCCCATGTGGTCATGGTGGGCGCTGCGCACCGAGGCGGTGGCGGTGATGTATTGGGGCC
TGGCGGGCAAGGTGCTGCTGGACCATCTGCGCGGCACGCCGTTCCTGCCCTGGTTCCTGTGGCTGTACGGCTGCCGCTTC
GGCTCCGGCGTGTTCATGGACACCACGGACATCACCGAATTCGACTGCATCGATGTGGGGGATTTCTGCGCCATCAACTC
GCTGTCGGCGCTGCAGACCCACCTTTACGAGGACCGGGTCATGAAGGTGGGCCGCGTCAAGCTGGGCACCGGCGTGACCG
TGGGCTCGGGCTCGACCGTGCTTTACGACACCGATGTGGGCGACTTCGCCCGGGTGGGCAAGCTGACCATCATCATGAAG
GGCGAAGGATTGCCGGCCCATTCCCAGTGGGAGGGCGCGCCGGCCCAGTCGGCCCGGGGCGAGCTGTGA

Upstream 100 bases:

>100_bases
TGGTGGGCGCCAAGCTGTGGATCGCCGGCCGGCGCACCTGGCCGAGGCCGACCGCCTGCCGCAGGTGCTGGCCGAGGCCG
GCATCACCGTGCTGGACACC

Downstream 100 bases:

>100_bases
CCGGTCAGCCGGTCAAGCGCTCGGTCAAGATCGCCGGCCACGCCACCAGCGTCACGCTGGAGGCGGAATTCTGGGACTGC
CTCAGGGAGTTGGCCGAAAG

Product: hypothetical protein

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: ATP-dependent valine adenylase; ValA; Valine activase; ATP-dependent D-valine adenylase; D-ValA; D-valine activase; Valine racemase [ATP-hydrolyzing]; ATP-dependent tryptophan adenylase; TrpA; Tryptophan activase; ATP-dependent D-leucine adenylase; D-LeuA; D-leucine activase; Leucine racemase [ATP-hydrolyzing]; ATP-dependent tryptophan/phenylalanine/tyrosine adenylase; Trp/Phe/TyrA; Tryptophan/phenylalanine/tyrosine activase; ATP-dependent D-leucine adenylase; D-LeuA; D-leucine activase; Leucine racemase [ATP-hydrolyzing] [H]

Number of amino acids: Translated: 1062; Mature: 1061

Protein sequence:

>1062_residues
MPTLLSLLPGDIPGLRVIILGGEACPAALAERWCRPGRRIFNSYGPTEATVVATMAEVEPGKPVTIGRPIPNYVCHVVDD
FIQPVAPGATGELLIGGPGVAAGYLGRPDLTAEKFIPNPWDTDGSAPVLYRSGDAVAIDGNGDITFHGRIDDQVKIRGFR
VELGEIEARLAALPGVNQAAVSLRTDDGIERLVATILPEAGAVIEGGALKEGLRAQLPAYMVPSHYLVVDELPRLISGKL
NRKALKDLPLDLSVGGGEQEEPATTTEAALLEAARRVFPGQVIAFEADFFLDLGGHSLLAAKFVSAVRETPELASLTLNE
IYSARTLRAMGALLDLRAPAAGAKPADLSFDPPTLRRRFLCGLAQAVAMPFILALTTAPWLGVFISYMLLSGEDASFFTE
MSTLMLTYAVINVGTISASIALKWVILGRTKPGRHKLWGPYYFRWWLAQRVVSVAHIKWFQGTPIMSIYLRLLGARVGSD
CVLAEMEAGAFDLVTIGNGVAIGGKTRLANAEAVGDELVIGPIVIGDDAYIGTSCMLSDGVVIETGGEVGDLTSIAAGTR
IGRYEHWDGSPGRKVGMVDEAALPEAAHAGFGRKLALTCLYGLMLVVLPPISLLPIFPAFFIFERLSDYFAGGEYATILP
LLAWPTAMALIAVTVLLIAVVRWSVLPVVTAGSYSIYGGFYVRKWIVALATELMLETLSSLYATVYMRLWYRLMGAKIGK
DAEISCNLAGRYDLTDIGPGCFIADEVVLGDECVRRGWMVLEPVKTEARVFVGNDAVVPPGAVIPTGALIGIKSRPPANE
QMSPGDTWFGNPPFKLPVRQRFDDVGADWTFAPPLWRRVWRAVFEAFAVSLPTALFITFGIMTVDLLAPSILARDYAIVL
PLFVAASVAISFSLALSSVAVKWLMMGVYRPTAKPMWSWWALRTEAVAVMYWGLAGKVLLDHLRGTPFLPWFLWLYGCRF
GSGVFMDTTDITEFDCIDVGDFCAINSLSALQTHLYEDRVMKVGRVKLGTGVTVGSGSTVLYDTDVGDFARVGKLTIIMK
GEGLPAHSQWEGAPAQSARGEL

Sequences:

>Translated_1062_residues
MPTLLSLLPGDIPGLRVIILGGEACPAALAERWCRPGRRIFNSYGPTEATVVATMAEVEPGKPVTIGRPIPNYVCHVVDD
FIQPVAPGATGELLIGGPGVAAGYLGRPDLTAEKFIPNPWDTDGSAPVLYRSGDAVAIDGNGDITFHGRIDDQVKIRGFR
VELGEIEARLAALPGVNQAAVSLRTDDGIERLVATILPEAGAVIEGGALKEGLRAQLPAYMVPSHYLVVDELPRLISGKL
NRKALKDLPLDLSVGGGEQEEPATTTEAALLEAARRVFPGQVIAFEADFFLDLGGHSLLAAKFVSAVRETPELASLTLNE
IYSARTLRAMGALLDLRAPAAGAKPADLSFDPPTLRRRFLCGLAQAVAMPFILALTTAPWLGVFISYMLLSGEDASFFTE
MSTLMLTYAVINVGTISASIALKWVILGRTKPGRHKLWGPYYFRWWLAQRVVSVAHIKWFQGTPIMSIYLRLLGARVGSD
CVLAEMEAGAFDLVTIGNGVAIGGKTRLANAEAVGDELVIGPIVIGDDAYIGTSCMLSDGVVIETGGEVGDLTSIAAGTR
IGRYEHWDGSPGRKVGMVDEAALPEAAHAGFGRKLALTCLYGLMLVVLPPISLLPIFPAFFIFERLSDYFAGGEYATILP
LLAWPTAMALIAVTVLLIAVVRWSVLPVVTAGSYSIYGGFYVRKWIVALATELMLETLSSLYATVYMRLWYRLMGAKIGK
DAEISCNLAGRYDLTDIGPGCFIADEVVLGDECVRRGWMVLEPVKTEARVFVGNDAVVPPGAVIPTGALIGIKSRPPANE
QMSPGDTWFGNPPFKLPVRQRFDDVGADWTFAPPLWRRVWRAVFEAFAVSLPTALFITFGIMTVDLLAPSILARDYAIVL
PLFVAASVAISFSLALSSVAVKWLMMGVYRPTAKPMWSWWALRTEAVAVMYWGLAGKVLLDHLRGTPFLPWFLWLYGCRF
GSGVFMDTTDITEFDCIDVGDFCAINSLSALQTHLYEDRVMKVGRVKLGTGVTVGSGSTVLYDTDVGDFARVGKLTIIMK
GEGLPAHSQWEGAPAQSARGEL
>Mature_1061_residues
PTLLSLLPGDIPGLRVIILGGEACPAALAERWCRPGRRIFNSYGPTEATVVATMAEVEPGKPVTIGRPIPNYVCHVVDDF
IQPVAPGATGELLIGGPGVAAGYLGRPDLTAEKFIPNPWDTDGSAPVLYRSGDAVAIDGNGDITFHGRIDDQVKIRGFRV
ELGEIEARLAALPGVNQAAVSLRTDDGIERLVATILPEAGAVIEGGALKEGLRAQLPAYMVPSHYLVVDELPRLISGKLN
RKALKDLPLDLSVGGGEQEEPATTTEAALLEAARRVFPGQVIAFEADFFLDLGGHSLLAAKFVSAVRETPELASLTLNEI
YSARTLRAMGALLDLRAPAAGAKPADLSFDPPTLRRRFLCGLAQAVAMPFILALTTAPWLGVFISYMLLSGEDASFFTEM
STLMLTYAVINVGTISASIALKWVILGRTKPGRHKLWGPYYFRWWLAQRVVSVAHIKWFQGTPIMSIYLRLLGARVGSDC
VLAEMEAGAFDLVTIGNGVAIGGKTRLANAEAVGDELVIGPIVIGDDAYIGTSCMLSDGVVIETGGEVGDLTSIAAGTRI
GRYEHWDGSPGRKVGMVDEAALPEAAHAGFGRKLALTCLYGLMLVVLPPISLLPIFPAFFIFERLSDYFAGGEYATILPL
LAWPTAMALIAVTVLLIAVVRWSVLPVVTAGSYSIYGGFYVRKWIVALATELMLETLSSLYATVYMRLWYRLMGAKIGKD
AEISCNLAGRYDLTDIGPGCFIADEVVLGDECVRRGWMVLEPVKTEARVFVGNDAVVPPGAVIPTGALIGIKSRPPANEQ
MSPGDTWFGNPPFKLPVRQRFDDVGADWTFAPPLWRRVWRAVFEAFAVSLPTALFITFGIMTVDLLAPSILARDYAIVLP
LFVAASVAISFSLALSSVAVKWLMMGVYRPTAKPMWSWWALRTEAVAVMYWGLAGKVLLDHLRGTPFLPWFLWLYGCRFG
SGVFMDTTDITEFDCIDVGDFCAINSLSALQTHLYEDRVMKVGRVKLGTGVTVGSGSTVLYDTDVGDFARVGKLTIIMKG
EGLPAHSQWEGAPAQSARGEL

Specific function: Activates the 7th to 12th amino acids (Val, D-Val, Trp, D-Leu, Xaa and D-Leu) in linear gramicidin and catalyzes the formation of the peptide bond between them. This enzyme is also responsible for the epimerization of the 8th (D-Val), the 10th (D- Leu) an

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 6 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI122937307, Length=242, Percent_Identity=25.6198347107438, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI187761345, Length=258, Percent_Identity=28.6821705426357, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI187761343, Length=258, Percent_Identity=28.6821705426357, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI38505220, Length=261, Percent_Identity=27.2030651340996, Blast_Score=77, Evalue=7e-14,
Organism=Homo sapiens, GI115511026, Length=246, Percent_Identity=25.609756097561, Blast_Score=74, Evalue=8e-13,
Organism=Homo sapiens, GI157311624, Length=254, Percent_Identity=25.5905511811024, Blast_Score=74, Evalue=8e-13,
Organism=Homo sapiens, GI157311622, Length=254, Percent_Identity=25.5905511811024, Blast_Score=74, Evalue=8e-13,
Organism=Homo sapiens, GI58082049, Length=253, Percent_Identity=25.296442687747, Blast_Score=73, Evalue=1e-12,
Organism=Escherichia coli, GI1786801, Length=338, Percent_Identity=35.7988165680473, Blast_Score=155, Evalue=1e-38,
Organism=Escherichia coli, GI1788107, Length=243, Percent_Identity=32.0987654320988, Blast_Score=92, Evalue=2e-19,
Organism=Escherichia coli, GI145693145, Length=267, Percent_Identity=28.8389513108614, Blast_Score=92, Evalue=3e-19,
Organism=Escherichia coli, GI1786810, Length=254, Percent_Identity=28.3464566929134, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17556356, Length=336, Percent_Identity=27.6785714285714, Blast_Score=89, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17560308, Length=252, Percent_Identity=30.5555555555556, Blast_Score=85, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17538037, Length=261, Percent_Identity=27.2030651340996, Blast_Score=83, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17557194, Length=270, Percent_Identity=27.7777777777778, Blast_Score=77, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI32563687, Length=245, Percent_Identity=27.7551020408163, Blast_Score=74, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17558820, Length=222, Percent_Identity=27.4774774774775, Blast_Score=72, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17559526, Length=245, Percent_Identity=24.0816326530612, Blast_Score=69, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6319591, Length=378, Percent_Identity=26.984126984127, Blast_Score=111, Evalue=7e-25,
Organism=Saccharomyces cerevisiae, GI6319699, Length=247, Percent_Identity=26.7206477732794, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24648676, Length=244, Percent_Identity=31.5573770491803, Blast_Score=114, Evalue=5e-25,
Organism=Drosophila melanogaster, GI18859661, Length=172, Percent_Identity=31.3953488372093, Blast_Score=69, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR023213
- InterPro:   IPR001242
- InterPro:   IPR010060
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 114435; Mature: 114304

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS50075 ACP_DOMAIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTLLSLLPGDIPGLRVIILGGEACPAALAERWCRPGRRIFNSYGPTEATVVATMAEVEP
CCCHHHHCCCCCCCEEEEEECCCCCHHHHHHHHCCCHHHHHHCCCCCCCEEEEEEHHCCC
GKPVTIGRPIPNYVCHVVDDFIQPVAPGATGELLIGGPGVAAGYLGRPDLTAEKFIPNPW
CCCEEECCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCHHHCCCCCC
DTDGSAPVLYRSGDAVAIDGNGDITFHGRIDDQVKIRGFRVELGEIEARLAALPGVNQAA
CCCCCCEEEEECCCEEEEECCCCEEEECCCCCEEEEEEEEEEHHHHHHHHHHCCCCCHHE
VSLRTDDGIERLVATILPEAGAVIEGGALKEGLRAQLPAYMVPSHYLVVDELPRLISGKL
EEEECCHHHHHHHHHHCCCCCCEEECCHHHHHHHHCCCCEECCCCEEEHHHHHHHHCCCC
NRKALKDLPLDLSVGGGEQEEPATTTEAALLEAARRVFPGQVIAFEADFFLDLGGHSLLA
CHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCEEEECCCCHHHH
AKFVSAVRETPELASLTLNEIYSARTLRAMGALLDLRAPAAGAKPADLSFDPPTLRRRFL
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHH
CGLAQAVAMPFILALTTAPWLGVFISYMLLSGEDASFFTEMSTLMLTYAVINVGTISASI
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHEEEEE
ALKWVILGRTKPGRHKLWGPYYFRWWLAQRVVSVAHIKWFQGTPIMSIYLRLLGARVGSD
EEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHCCCC
CVLAEMEAGAFDLVTIGNGVAIGGKTRLANAEAVGDELVIGPIVIGDDAYIGTSCMLSDG
EEEEECCCCCEEEEEECCCEEECCCCEECCHHHCCCCEEEEEEEECCCCEECCEEEEECC
VVIETGGEVGDLTSIAAGTRIGRYEHWDGSPGRKVGMVDEAALPEAAHAGFGRKLALTCL
EEEECCCCCCCHHHHHHCCCCCCCCCCCCCCCCEECCCCHHCCCHHHHCCCCHHHHHHHH
YGLMLVVLPPISLLPIFPAFFIFERLSDYFAGGEYATILPLLAWPTAMALIAVTVLLIAV
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VRWSVLPVVTAGSYSIYGGFYVRKWIVALATELMLETLSSLYATVYMRLWYRLMGAKIGK
HHHHHHHEEECCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DAEISCNLAGRYDLTDIGPGCFIADEVVLGDECVRRGWMVLEPVKTEARVFVGNDAVVPP
CCEEEEEECCCCCCCCCCCCCEEECCEEECHHHHHCCCEEEEECCCCCEEEECCCCCCCC
GAVIPTGALIGIKSRPPANEQMSPGDTWFGNPPFKLPVRQRFDDVGADWTFAPPLWRRVW
CCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHH
RAVFEAFAVSLPTALFITFGIMTVDLLAPSILARDYAIVLPLFVAASVAISFSLALSSVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VKWLMMGVYRPTAKPMWSWWALRTEAVAVMYWGLAGKVLLDHLRGTPFLPWFLWLYGCRF
HHHHHHHHCCCCCCCHHHHHHHHHHHEEEEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHC
GSGVFMDTTDITEFDCIDVGDFCAINSLSALQTHLYEDRVMKVGRVKLGTGVTVGSGSTV
CCCEEEECCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHCEEEECCCEEECCCCEE
LYDTDVGDFARVGKLTIIMKGEGLPAHSQWEGAPAQSARGEL
EEECCCCHHHHCCEEEEEEECCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PTLLSLLPGDIPGLRVIILGGEACPAALAERWCRPGRRIFNSYGPTEATVVATMAEVEP
CCHHHHCCCCCCCEEEEEECCCCCHHHHHHHHCCCHHHHHHCCCCCCCEEEEEEHHCCC
GKPVTIGRPIPNYVCHVVDDFIQPVAPGATGELLIGGPGVAAGYLGRPDLTAEKFIPNPW
CCCEEECCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCHHHCCCCCC
DTDGSAPVLYRSGDAVAIDGNGDITFHGRIDDQVKIRGFRVELGEIEARLAALPGVNQAA
CCCCCCEEEEECCCEEEEECCCCEEEECCCCCEEEEEEEEEEHHHHHHHHHHCCCCCHHE
VSLRTDDGIERLVATILPEAGAVIEGGALKEGLRAQLPAYMVPSHYLVVDELPRLISGKL
EEEECCHHHHHHHHHHCCCCCCEEECCHHHHHHHHCCCCEECCCCEEEHHHHHHHHCCCC
NRKALKDLPLDLSVGGGEQEEPATTTEAALLEAARRVFPGQVIAFEADFFLDLGGHSLLA
CHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCEEEECCCCHHHH
AKFVSAVRETPELASLTLNEIYSARTLRAMGALLDLRAPAAGAKPADLSFDPPTLRRRFL
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHH
CGLAQAVAMPFILALTTAPWLGVFISYMLLSGEDASFFTEMSTLMLTYAVINVGTISASI
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHEEEEE
ALKWVILGRTKPGRHKLWGPYYFRWWLAQRVVSVAHIKWFQGTPIMSIYLRLLGARVGSD
EEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHCCCC
CVLAEMEAGAFDLVTIGNGVAIGGKTRLANAEAVGDELVIGPIVIGDDAYIGTSCMLSDG
EEEEECCCCCEEEEEECCCEEECCCCEECCHHHCCCCEEEEEEEECCCCEECCEEEEECC
VVIETGGEVGDLTSIAAGTRIGRYEHWDGSPGRKVGMVDEAALPEAAHAGFGRKLALTCL
EEEECCCCCCCHHHHHHCCCCCCCCCCCCCCCCEECCCCHHCCCHHHHCCCCHHHHHHHH
YGLMLVVLPPISLLPIFPAFFIFERLSDYFAGGEYATILPLLAWPTAMALIAVTVLLIAV
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VRWSVLPVVTAGSYSIYGGFYVRKWIVALATELMLETLSSLYATVYMRLWYRLMGAKIGK
HHHHHHHEEECCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DAEISCNLAGRYDLTDIGPGCFIADEVVLGDECVRRGWMVLEPVKTEARVFVGNDAVVPP
CCEEEEEECCCCCCCCCCCCCEEECCEEECHHHHHCCCEEEEECCCCCEEEECCCCCCCC
GAVIPTGALIGIKSRPPANEQMSPGDTWFGNPPFKLPVRQRFDDVGADWTFAPPLWRRVW
CCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHH
RAVFEAFAVSLPTALFITFGIMTVDLLAPSILARDYAIVLPLFVAASVAISFSLALSSVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VKWLMMGVYRPTAKPMWSWWALRTEAVAVMYWGLAGKVLLDHLRGTPFLPWFLWLYGCRF
HHHHHHHHCCCCCCCHHHHHHHHHHHEEEEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHC
GSGVFMDTTDITEFDCIDVGDFCAINSLSALQTHLYEDRVMKVGRVKLGTGVTVGSGSTV
CCCEEEECCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHCEEEECCCEEECCCCEE
LYDTDVGDFARVGKLTIIMKGEGLPAHSQWEGAPAQSARGEL
EEECCCCHHHHCCEEEEEEECCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA