Click here to switch to the map view.

The map label for this gene is aphA [H]

Identifier: 83310363

GI number: 83310363

Start: 1346729

End: 1348786

Strand: Reverse

Name: aphA [H]

Synonym: amb1264

Alternate gene names: 83310363

Gene position: 1348786-1346729 (Counterclockwise)

Preceding gene: 83310364

Following gene: 83310362

Centisome position: 27.15

GC content: 66.86

Gene sequence:

>2058_bases
GTGGAGTTCCGCCCCTCCAACCGCCGCATCATGGTGGCGCTGCTGGGAGCCATGCTCCTGGTGCTGTGGGGCTTCGTCAC
CTATTGGTCATGGTCCCAGCGCAAGGGCATCATGGCGTCGAGCACCGTCATCCTGGAGCAATTGACCTCGGCGGCCGAGG
AACAGACCCTGCGCCTGTTCCGCCATGCCGAGACGTCGCTGGTGGTCAGCAATCACTGGCTGGCCGATCATCCGCAACAG
AGCCCGGGCGGCAATCCCGCCTTCATCACCCTGGTCGACCGCCTGCGCCAGATGTCCGACGGCATGCTTGACATCCGCAT
GGTCACAAGCACGGGCGGCCTGCACTACATCCCCTGGCGCGGCCCCAAGCCGCTCGCCGACGTGTCCGACCGCGACTATT
TCAAAGCCCAGGCGCGTATGGAGACCCGCGGCTTCTACATCGGCAATCCGGTGGTCAGCCGGGTGACGGGCAAGTGGGGC
ATCCCGGTCTCCATCCCGGCCGACCGGAACGGCGGCGACATCGCCGTGCTGTTCGGCGCCATCGAACTGGACCGCATCGT
CAAGACCTTCGAGGCCGAACGCATCAAGCCGCACGGCTCCATCGCCGTGCTTCGGGCCGATGGCACCTTCTTGTTCCGGG
TCCCGTCCGAGGACCACGTGGCCGGGCTCAACATCGCCGACACGCCGTCGTTCCGCGACAACTACGCCCTGTCGCTCAAG
GGGGTCTTCCGCTCCTCCAGCCAGTTCATCGACGGCAAGGAGCGGCTGGTGTCGTATCAGAGGCTGCGCGACTATCCCCT
GATCGTCATCGTCACCGCCGGAATCGACGACCTGCTGGCTCCCTGGCGCCGCGAGACAGCCACCCTGGTGGCCATCGCCG
GACTGGTCACCCTGGCCATCGGCCTGCTGGCCCTGATCCTGATCCGGGCCATGAAGGCCGAGGAGAAGGCCCAGAAGGCC
ACCGAACGCGCCAAGCGCGAGGCCGAGCTGATCCTGGCCGCCGCCGGCGAAGGGATTTGCGGCATCGATATCCAGGGCCG
GGTCACCTTCATGAATCCGGCGGCGCGCTCCATGCTGGGCTGGCTGCATGAGGACCCCATCGGCCGAAACCTGCATGCGG
CCAACCATCACAGCCGCCCGGACGGCGCCGCCTATCCCGGCAGCGAATGCCCCATCGCCCATACCCTGGCCGACGGCCAG
ACCCGCGAAGTGCAGGGCGAGACGTTCTGGCGGCTGAACGGCACCCAGTTCCCGGTAGAGATGATCGCCACCGGCCTGGT
GGAGGATGGCGGCGTCAAGGGCGCCGTGCTGATGTTCCGCGACATCAGCGACCGGCTGGCCTCGGAACAGGCCCTGAAGG
CGCAGGCCACCGAACTGTCGCGCTCCAATGCCGACCTGGAACAGTTCGCCTATGTGGCCAGCCACGACCTGCGCGAGCCG
CTGCGGCAGGTGGCCAGCTTCGTCTCCCTGCTGGAGCGCCGCTATGGCCCCACCCTGGACGACGACGCCCGGGACTATAT
CACCTATGCCCGCGAAGGCGCCAAGCGCATGGACCGGCTGATCATCGACCTACTGGATTTCTCGCGCATCGGCCATCATT
CGCAGGCGGTGCAACAGGTCAATCTCGGCAGCGTCATCGACGAGGCCATCGCCAACCTGGGCACCGTCATCGTCGAGCAC
GGCGCCCAGGTGGATCGCGCCGCGGAGATGCCGGTGCTGGGGCTGGTTCGCGACGACATGGTGCGCCTGTTCCAGAATCT
GATCGGCAACGCCCTCAAATACCACCACCCCGAGCGGACCCCCATCGTCCGCATCGCCGCCCGACGCGACGACGAGGGAT
GGGTGGTTTCGGTCATCGACAACGGCCTGGGCATCGACCCGCAATTCTCGGAGCGCATCTTTGGCATCTTCCAGCGCCTG
CACACCCGCGACAAGTTCGAGGGCACCGGCATCGGGCTGGCCATCTGCAAGAAGATCGTCGAGCGGGCAGGCGGACGGAT
CTGGGTCGAACCCGCCGAGGGCGGCGGCAGCGTCTTCAACGTCCGCCTGCCCGCTTGA

Upstream 100 bases:

>100_bases
CACCATCGTGCGCGGCCGCACGGTCATGCGCGACGGCCAGTTGCTAGGCCAGGCCTCGGGCGAGCCGGTCCGCTTCCAGG
AAACCCTGTAGGCCCGGCCG

Downstream 100 bases:

>100_bases
CCGCCATCATGCCCAGGAAACGCCGACAGGGGTAGTCTTGGCCGAGCAAGAGGAGGCTTTGGTCCATGCTCACCCAAGAC
GATATCCGCGAGGCGCTGCG

Product: Signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 685; Mature: 685

Protein sequence:

>685_residues
MEFRPSNRRIMVALLGAMLLVLWGFVTYWSWSQRKGIMASSTVILEQLTSAAEEQTLRLFRHAETSLVVSNHWLADHPQQ
SPGGNPAFITLVDRLRQMSDGMLDIRMVTSTGGLHYIPWRGPKPLADVSDRDYFKAQARMETRGFYIGNPVVSRVTGKWG
IPVSIPADRNGGDIAVLFGAIELDRIVKTFEAERIKPHGSIAVLRADGTFLFRVPSEDHVAGLNIADTPSFRDNYALSLK
GVFRSSSQFIDGKERLVSYQRLRDYPLIVIVTAGIDDLLAPWRRETATLVAIAGLVTLAIGLLALILIRAMKAEEKAQKA
TERAKREAELILAAAGEGICGIDIQGRVTFMNPAARSMLGWLHEDPIGRNLHAANHHSRPDGAAYPGSECPIAHTLADGQ
TREVQGETFWRLNGTQFPVEMIATGLVEDGGVKGAVLMFRDISDRLASEQALKAQATELSRSNADLEQFAYVASHDLREP
LRQVASFVSLLERRYGPTLDDDARDYITYAREGAKRMDRLIIDLLDFSRIGHHSQAVQQVNLGSVIDEAIANLGTVIVEH
GAQVDRAAEMPVLGLVRDDMVRLFQNLIGNALKYHHPERTPIVRIAARRDDEGWVVSVIDNGLGIDPQFSERIFGIFQRL
HTRDKFEGTGIGLAICKKIVERAGGRIWVEPAEGGGSVFNVRLPA

Sequences:

>Translated_685_residues
MEFRPSNRRIMVALLGAMLLVLWGFVTYWSWSQRKGIMASSTVILEQLTSAAEEQTLRLFRHAETSLVVSNHWLADHPQQ
SPGGNPAFITLVDRLRQMSDGMLDIRMVTSTGGLHYIPWRGPKPLADVSDRDYFKAQARMETRGFYIGNPVVSRVTGKWG
IPVSIPADRNGGDIAVLFGAIELDRIVKTFEAERIKPHGSIAVLRADGTFLFRVPSEDHVAGLNIADTPSFRDNYALSLK
GVFRSSSQFIDGKERLVSYQRLRDYPLIVIVTAGIDDLLAPWRRETATLVAIAGLVTLAIGLLALILIRAMKAEEKAQKA
TERAKREAELILAAAGEGICGIDIQGRVTFMNPAARSMLGWLHEDPIGRNLHAANHHSRPDGAAYPGSECPIAHTLADGQ
TREVQGETFWRLNGTQFPVEMIATGLVEDGGVKGAVLMFRDISDRLASEQALKAQATELSRSNADLEQFAYVASHDLREP
LRQVASFVSLLERRYGPTLDDDARDYITYAREGAKRMDRLIIDLLDFSRIGHHSQAVQQVNLGSVIDEAIANLGTVIVEH
GAQVDRAAEMPVLGLVRDDMVRLFQNLIGNALKYHHPERTPIVRIAARRDDEGWVVSVIDNGLGIDPQFSERIFGIFQRL
HTRDKFEGTGIGLAICKKIVERAGGRIWVEPAEGGGSVFNVRLPA
>Mature_685_residues
MEFRPSNRRIMVALLGAMLLVLWGFVTYWSWSQRKGIMASSTVILEQLTSAAEEQTLRLFRHAETSLVVSNHWLADHPQQ
SPGGNPAFITLVDRLRQMSDGMLDIRMVTSTGGLHYIPWRGPKPLADVSDRDYFKAQARMETRGFYIGNPVVSRVTGKWG
IPVSIPADRNGGDIAVLFGAIELDRIVKTFEAERIKPHGSIAVLRADGTFLFRVPSEDHVAGLNIADTPSFRDNYALSLK
GVFRSSSQFIDGKERLVSYQRLRDYPLIVIVTAGIDDLLAPWRRETATLVAIAGLVTLAIGLLALILIRAMKAEEKAQKA
TERAKREAELILAAAGEGICGIDIQGRVTFMNPAARSMLGWLHEDPIGRNLHAANHHSRPDGAAYPGSECPIAHTLADGQ
TREVQGETFWRLNGTQFPVEMIATGLVEDGGVKGAVLMFRDISDRLASEQALKAQATELSRSNADLEQFAYVASHDLREP
LRQVASFVSLLERRYGPTLDDDARDYITYAREGAKRMDRLIIDLLDFSRIGHHSQAVQQVNLGSVIDEAIANLGTVIVEH
GAQVDRAAEMPVLGLVRDDMVRLFQNLIGNALKYHHPERTPIVRIAARRDDEGWVVSVIDNGLGIDPQFSERIFGIFQRL
HTRDKFEGTGIGLAICKKIVERAGGRIWVEPAEGGGSVFNVRLPA

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=376, Percent_Identity=27.3936170212766, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI145693157, Length=257, Percent_Identity=28.4046692607004, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1788713, Length=254, Percent_Identity=22.8346456692913, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1790436, Length=221, Percent_Identity=28.0542986425339, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1790346, Length=245, Percent_Identity=26.1224489795918, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1786912, Length=217, Percent_Identity=30.4147465437788, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1789149, Length=237, Percent_Identity=28.6919831223629, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI48994928, Length=257, Percent_Identity=26.8482490272374, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI87081816, Length=231, Percent_Identity=29.004329004329, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 75754; Mature: 75754

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFRPSNRRIMVALLGAMLLVLWGFVTYWSWSQRKGIMASSTVILEQLTSAAEEQTLRLF
CCCCCCCCEEHHHHHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RHAETSLVVSNHWLADHPQQSPGGNPAFITLVDRLRQMSDGMLDIRMVTSTGGLHYIPWR
HHCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCEEEECCC
GPKPLADVSDRDYFKAQARMETRGFYIGNPVVSRVTGKWGIPVSIPADRNGGDIAVLFGA
CCCCCCCCCCCHHHHHHHHHHHCCEEECCHHHHHHCCCCCCEEECCCCCCCCCEEEEEEH
IELDRIVKTFEAERIKPHGSIAVLRADGTFLFRVPSEDHVAGLNIADTPSFRDNYALSLK
HHHHHHHHHHHHHHCCCCCCEEEEEECCEEEEECCCCCCEECCCCCCCCCCCCCEEEEEE
GVFRSSSQFIDGKERLVSYQRLRDYPLIVIVTAGIDDLLAPWRRETATLVAIAGLVTLAI
HHHCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCHHHHCCHHHHHHHHHHHHHHHHHHH
GLLALILIRAMKAEEKAQKATERAKREAELILAAAGEGICGIDIQGRVTFMNPAARSMLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCEEEEEECCEEEEECHHHHHHHH
WLHEDPIGRNLHAANHHSRPDGAAYPGSECPIAHTLADGQTREVQGETFWRLNGTQFPVE
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCEEEEECCCCCCHH
MIATGLVEDGGVKGAVLMFRDISDRLASEQALKAQATELSRSNADLEQFAYVASHDLREP
HHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
LRQVASFVSLLERRYGPTLDDDARDYITYAREGAKRMDRLIIDLLDFSRIGHHSQAVQQV
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
NLGSVIDEAIANLGTVIVEHGAQVDRAAEMPVLGLVRDDMVRLFQNLIGNALKYHHPERT
HHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PIVRIAARRDDEGWVVSVIDNGLGIDPQFSERIFGIFQRLHTRDKFEGTGIGLAICKKIV
CEEEEEEECCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
ERAGGRIWVEPAEGGGSVFNVRLPA
HHCCCEEEEEECCCCCCEEEEECCC
>Mature Secondary Structure
MEFRPSNRRIMVALLGAMLLVLWGFVTYWSWSQRKGIMASSTVILEQLTSAAEEQTLRLF
CCCCCCCCEEHHHHHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RHAETSLVVSNHWLADHPQQSPGGNPAFITLVDRLRQMSDGMLDIRMVTSTGGLHYIPWR
HHCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCEEEECCC
GPKPLADVSDRDYFKAQARMETRGFYIGNPVVSRVTGKWGIPVSIPADRNGGDIAVLFGA
CCCCCCCCCCCHHHHHHHHHHHCCEEECCHHHHHHCCCCCCEEECCCCCCCCCEEEEEEH
IELDRIVKTFEAERIKPHGSIAVLRADGTFLFRVPSEDHVAGLNIADTPSFRDNYALSLK
HHHHHHHHHHHHHHCCCCCCEEEEEECCEEEEECCCCCCEECCCCCCCCCCCCCEEEEEE
GVFRSSSQFIDGKERLVSYQRLRDYPLIVIVTAGIDDLLAPWRRETATLVAIAGLVTLAI
HHHCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCHHHHCCHHHHHHHHHHHHHHHHHHH
GLLALILIRAMKAEEKAQKATERAKREAELILAAAGEGICGIDIQGRVTFMNPAARSMLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCEEEEEECCEEEEECHHHHHHHH
WLHEDPIGRNLHAANHHSRPDGAAYPGSECPIAHTLADGQTREVQGETFWRLNGTQFPVE
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCEEEEECCCCCCHH
MIATGLVEDGGVKGAVLMFRDISDRLASEQALKAQATELSRSNADLEQFAYVASHDLREP
HHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
LRQVASFVSLLERRYGPTLDDDARDYITYAREGAKRMDRLIIDLLDFSRIGHHSQAVQQV
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
NLGSVIDEAIANLGTVIVEHGAQVDRAAEMPVLGLVRDDMVRLFQNLIGNALKYHHPERT
HHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PIVRIAARRDDEGWVVSVIDNGLGIDPQFSERIFGIFQRLHTRDKFEGTGIGLAICKKIV
CEEEEEEECCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
ERAGGRIWVEPAEGGGSVFNVRLPA
HHCCCEEEEEECCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]