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The map label for this gene is mtxA [H]

Identifier: 83310302

GI number: 83310302

Start: 1275434

End: 1276561

Strand: Reverse

Name: mtxA [H]

Synonym: amb1203

Alternate gene names: 83310302

Gene position: 1276561-1275434 (Counterclockwise)

Preceding gene: 83310303

Following gene: 83310296

Centisome position: 25.7

GC content: 64.63

Gene sequence:

>1128_bases
ATGGTTTGCGACAGCAAACAGGAGTGTTCGATGCTGGCTGCCGTGGAGACCATCCATCACGAGTTGGGGACGGCCATCGG
TCTCGCCAAATGCCGGAAGTGCGGCTGTCTTGGCGAATTCCTTGACGGTCTGGTGTTGGCAGTGGACCTGCCCACCGAAG
CGATGGCCCTGGTCGAGGAGGCTCGGGCAGGGCGGCAGCGGATGGAGGCCGTCGAATACCCGTGCCTCGGCTGCTCCCAC
TGCTATCCGGCGGTGGCCTCCAATGCTCTGGCTCAAGCGTTCCCCCAGCTTGATCTCCATGCGGCCTGCGGTTTCGAGAT
CCGGGAGGGGTGGCCGCCGGTTCCCGGCGATTACTTCGTGCTGTGCCATGGGGCTGATTGCACCGTGGCCGTCTCCACCC
TGGGCGATGTCGCCCTGGCAGCACGGATCGCCGATCTCAAGCCACCGGCCCTGTGCATGGTCGGCAAGACCGAAACCGAG
AACATCGGCATCGACAAGGTGGTGCGCAACGTCGCCGCCAATCCTGACATCACCACGCTCATTCTTGTCGGCCAAGACCC
GCCGGGGCACCAGCCGGGCCGCACGCTGCTGGCCCTGGCCGAAAACGGCGTCGATGAGGCCATGCGGGTGATCGGCTCAC
CCGGCAAGCGCCCGATTTTGCGGAACGTGACCCCGGACGAGGTGGCGACCTTCAGGCAACGTGTCCAGATCATCGACCTG
ATCGGGGAAATCGACCCAGGGCGTATCATCGCTGCTATCGAACAGCACAACACCCCGGCCCCGCAGAAGCCGTCCTGCGG
CTGCTCGTCCTGTCCCACCACGTCCCCGGCGACCAGTGAACCGCCGATGGTCCAGGCCGGGGAGCCGAGATCCATCGAGA
TGGACAAGGCGGGCTACTTCGTGGTCCTGCCGCAACGCCCGGAGAGACGGCTTCTCGTCGAGCATTACGGCTACGACAAC
GCCTTGCTGCGGCGAATCGAAGGGGCAGATTCCCGCACCATCTACTGGACGATCATCGAGAACGGCTGGGTGAGCCAACT
CAGCCACGCCGCCTATCTCGGCAAGGAGTTGGCGCGTGCCGAAGCGGCGATGCTGCACGGCTATGAATACACCCAGGATG
GCGCCTGA

Upstream 100 bases:

>100_bases
GCCATCGCCGTCGTGGCCCTGCTGTTCTGGCGGGGAGATCGATGATGATGGCGCAACGGAATATTCCGTCATTCTAATGA
ATTGTGGTGCCCGTCGTGCT

Downstream 100 bases:

>100_bases
CCCGAAACCCCACCAGCAGGACGTCGGTATCGTTCTGGCGAACACAGGTTGAGGGGGCAATAACTCAATGCCCCAACACT
TCCCGCTGCCGCTCCCACTC

Product: tetrahydromethanopterin S-methyltransferase subunit A

Products: 5,6,7,8-tetrahydromethanopterin; 2-(methylthio)ethanesulfonate

Alternate protein names: NA

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MVCDSKQECSMLAAVETIHHELGTAIGLAKCRKCGCLGEFLDGLVLAVDLPTEAMALVEEARAGRQRMEAVEYPCLGCSH
CYPAVASNALAQAFPQLDLHAACGFEIREGWPPVPGDYFVLCHGADCTVAVSTLGDVALAARIADLKPPALCMVGKTETE
NIGIDKVVRNVAANPDITTLILVGQDPPGHQPGRTLLALAENGVDEAMRVIGSPGKRPILRNVTPDEVATFRQRVQIIDL
IGEIDPGRIIAAIEQHNTPAPQKPSCGCSSCPTTSPATSEPPMVQAGEPRSIEMDKAGYFVVLPQRPERRLLVEHYGYDN
ALLRRIEGADSRTIYWTIIENGWVSQLSHAAYLGKELARAEAAMLHGYEYTQDGA

Sequences:

>Translated_375_residues
MVCDSKQECSMLAAVETIHHELGTAIGLAKCRKCGCLGEFLDGLVLAVDLPTEAMALVEEARAGRQRMEAVEYPCLGCSH
CYPAVASNALAQAFPQLDLHAACGFEIREGWPPVPGDYFVLCHGADCTVAVSTLGDVALAARIADLKPPALCMVGKTETE
NIGIDKVVRNVAANPDITTLILVGQDPPGHQPGRTLLALAENGVDEAMRVIGSPGKRPILRNVTPDEVATFRQRVQIIDL
IGEIDPGRIIAAIEQHNTPAPQKPSCGCSSCPTTSPATSEPPMVQAGEPRSIEMDKAGYFVVLPQRPERRLLVEHYGYDN
ALLRRIEGADSRTIYWTIIENGWVSQLSHAAYLGKELARAEAAMLHGYEYTQDGA
>Mature_375_residues
MVCDSKQECSMLAAVETIHHELGTAIGLAKCRKCGCLGEFLDGLVLAVDLPTEAMALVEEARAGRQRMEAVEYPCLGCSH
CYPAVASNALAQAFPQLDLHAACGFEIREGWPPVPGDYFVLCHGADCTVAVSTLGDVALAARIADLKPPALCMVGKTETE
NIGIDKVVRNVAANPDITTLILVGQDPPGHQPGRTLLALAENGVDEAMRVIGSPGKRPILRNVTPDEVATFRQRVQIIDL
IGEIDPGRIIAAIEQHNTPAPQKPSCGCSSCPTTSPATSEPPMVQAGEPRSIEMDKAGYFVVLPQRPERRLLVEHYGYDN
ALLRRIEGADSRTIYWTIIENGWVSQLSHAAYLGKELARAEAAMLHGYEYTQDGA

Specific function: Unknown

COG id: COG4063

COG function: function code H; Tetrahydromethanopterin S-methyltransferase, subunit A

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MtrA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013340 [H]

Pfam domain/function: PF04208 MtrA [H]

EC number: 2.1.1.86

Molecular weight: Translated: 40362; Mature: 40362

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
4.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVCDSKQECSMLAAVETIHHELGTAIGLAKCRKCGCLGEFLDGLVLAVDLPTEAMALVEE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCEEEEEECCHHHHHHHHH
ARAGRQRMEAVEYPCLGCSHCYPAVASNALAQAFPQLDLHAACGFEIREGWPPVPGDYFV
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHCCCCHHCCCCCCCCCEEE
LCHGADCTVAVSTLGDVALAARIADLKPPALCMVGKTETENIGIDKVVRNVAANPDITTL
EEECCCCEEEHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHCCCCCCEEE
ILVGQDPPGHQPGRTLLALAENGVDEAMRVIGSPGKRPILRNVTPDEVATFRQRVQIIDL
EEEECCCCCCCCCCEEEEHHHCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
IGEIDPGRIIAAIEQHNTPAPQKPSCGCSSCPTTSPATSEPPMVQAGEPRSIEMDKAGYF
HCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCEEECCCCEE
VVLPQRPERRLLVEHYGYDNALLRRIEGADSRTIYWTIIENGWVSQLSHAAYLGKELARA
EEECCCCCHHHHHHHCCCCHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHH
EAAMLHGYEYTQDGA
HHHHHCCCCCCCCCC
>Mature Secondary Structure
MVCDSKQECSMLAAVETIHHELGTAIGLAKCRKCGCLGEFLDGLVLAVDLPTEAMALVEE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCEEEEEECCHHHHHHHHH
ARAGRQRMEAVEYPCLGCSHCYPAVASNALAQAFPQLDLHAACGFEIREGWPPVPGDYFV
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHCCCCHHCCCCCCCCCEEE
LCHGADCTVAVSTLGDVALAARIADLKPPALCMVGKTETENIGIDKVVRNVAANPDITTL
EEECCCCEEEHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHCCCCCCEEE
ILVGQDPPGHQPGRTLLALAENGVDEAMRVIGSPGKRPILRNVTPDEVATFRQRVQIIDL
EEEECCCCCCCCCCEEEEHHHCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
IGEIDPGRIIAAIEQHNTPAPQKPSCGCSSCPTTSPATSEPPMVQAGEPRSIEMDKAGYF
HCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCEEECCCCEE
VVLPQRPERRLLVEHYGYDNALLRRIEGADSRTIYWTIIENGWVSQLSHAAYLGKELARA
EEECCCCCHHHHHHHCCCCHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHH
EAAMLHGYEYTQDGA
HHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 5-methyl-5,6,7,8-tetrahydromethanopterin; 2-mercaptoethanesulfonate

Specific reaction: 5-methyl-5,6,7,8-tetrahydromethanopterin + 2-mercaptoethanesulfonate = 5,6,7,8-tetrahydromethanopterin + 2-(methylthio)ethanesulfonate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11932238 [H]