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The map label for this gene is luxQ [H]

Identifier: 83310211

GI number: 83310211

Start: 1185372

End: 1187435

Strand: Reverse

Name: luxQ [H]

Synonym: amb1112

Alternate gene names: 83310211

Gene position: 1187435-1185372 (Counterclockwise)

Preceding gene: 83310212

Following gene: 83310207

Centisome position: 23.91

GC content: 67.73

Gene sequence:

>2064_bases
ATGACCGACCGCATCGCCGAGCTTGTCGCCGAGAACGCCCTGCTGCGCGGCGAGATCCGCGTCGCCCGCGAGGCCGCCGA
GATCACCGCCCGGCTGGTGGTCAAGCAGTTCGAGGAGACCGAAAGGCTGCTCGACCGCTTCCAGAGCGCCAACGCCCAAC
GTCAGGCGGTGCTGGACGCGGCGCTGCAGATGTCGATCATCGCCACCGACATGAACGGCAAAGTGCTGCTGTTCAACCGC
GGCGCCGAGACCCTGCTGGGCTATGCCAGCGACGAGGTGGTAGGCCAAAGCACCCTGCTGGACTTCCTGCTGCCCGAGGA
GGTCGCCGCCCATGCCGACGAGCTGGCCGCCGAACTGGGCCATGCGGTCTCGCCGGAGACCCTGTTCGCCGAATACGTCC
GGCACGGCCTGATCTCGGCCCGGGAATGGACCTACCGGCGCAAGGACGGCACCCGCTTTCCCGTCAGCCTGTCCATCACG
CCCCTGAAGGGCGGCGACGGCGGTCTGGCCGGCACCCTGGCGGCGGCCATGGACATCACCGAGCGCAAATGGGCCGAGGA
GGAGGCCCACCGGGCCAAGCAGGCGGCCGAGGCGGCCAATCAGGCCAAGAGCAGCTTCCTGGCCAATATGAGCCACGAAC
TGCGCACGCCCTTGAACGCCATCATCGGCTACAGCGAGATGCTGCAGGAAGAGATGGAGGACCTGGGCCAGGACGATCTG
ATTCCCGATCTGGCCAAGATCCATTCCGCCGGCCGCCACCTGCTGACCCTGATCAACGACGTGCTGGACATCTCCAAGAT
CGAAGCGGGCAAGATGGACCTGTTCGTCGAGGCGTTCGAGATCGCTCCCATGGTGGCCGACGTGGTCGCCACCATCTCGC
CGCTGATCCAGAAGAACGGCAATACCCTGGTGGTTGACGGCGCCGGGGAGATCGGCGCCATGGAGGCCGATCTGACCAAG
GTGCGCCAGACGCTGTTCAACCTGCTCAGCAATGCCAGCAAGTTCACCTCGGACGGTACCATCACCCTGTCCACCCGCCG
CCAGGGCGAGTGGATCGAATTCGCCGTGGCCGATACCGGCATCGGCATGGCGCCCGCCGAACTGGACCGCCTGTTCCAGG
CCTTCTCGCAGGCCGATGCCTCCACCACCCGCAAGTTCGGCGGCACCGGCCTGGGCCTGGCCATCAGCCGCACCTTCTGC
CGCATGATGGGCGGCGACATCGCGGTGGCGAGCGAACCGGGGCGGGGCACCACCTTCACCGTGCGCCTGCCCGCGGTTTC
CGCCAGCCCCAAGGCGGCACGACCGGCCGGCGCCATCGAGTCCGGCCCGGAGCTGCCCCTGGTGCTGGTCATCGACGACG
ACGCCGTGGCCCGCGACCTTCTCGGCCGCTTCCTGGACGAGAACGGCTTTCGGGCGCGCTTTGCCGCCGACGGGCCGCTG
GGCCTGGAGATGGCGCGCGCCCTCCGGCCGGCGGCCATCACCCTGGACGTGATGATGCCGGGCATGGACGGCTGGTCGGT
GCTGACCGCGCTGAAGACCGACCCGGAACTGGCGGCGATTCCGGTGATCATGGTGTCGGTGGTGGAGAATCAGGCCCTGG
GCTACGCACTGGGCGCCCACCACTTCATGTCCAAGCCCATCGACCGCGACCAATTGGCCGAGGTGCTGTCCCGCTTCAAG
GAAGCCGGCCCCATCGAACGCATCCTGGTGGTGGAGGACGACCACACCAACCGCGAGATGCTGCGCCGCATGCTGGTCAA
GGAGGGCTGGTCGGTGATCGAGGCAGCCAATGGGCGGATCGCCCTGGAACGCGTCGCCGAATCCCGCCCCGACCTGATCC
TGCTGGACCTGATGATGCCCGAGATGGATGGCTTTGAATTCGTCTCCGAGCTTCGCCGCCATTCCGCCTGGCACGCGATT
CCGGTGGTGGTCCTCACCGCCAAGGATATCGGCCAGGATGACCGCGACCGGCTGGCCGGGGGCGTCCAGAAGGTGCTGCA
GAAGGGCGCGGCGGACAACGAGACCCTGCTGACCGAGCTGAAGCGCCTGGTCACCCCGGGCTGA

Upstream 100 bases:

>100_bases
GCGCGGTGCCCGAGGTGATCCTGGTGGGCGGCGAGGCGCCCGCCGGGGACATGCTCGTCGCCGCCCTTGCCGCCCGTGCC
GTCGAGGAGGCATCCAAGCC

Downstream 100 bases:

>100_bases
CCCCGCCAGGCCCCTCAGGCCATGTCCCGATGAGACCGCCTCATCGGGACATGGCCTGAGGGGCGAGCGCTAAATCTGAT
ACGCTCCTCCCCCCGACTTG

Product: Signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 687; Mature: 686

Protein sequence:

>687_residues
MTDRIAELVAENALLRGEIRVAREAAEITARLVVKQFEETERLLDRFQSANAQRQAVLDAALQMSIIATDMNGKVLLFNR
GAETLLGYASDEVVGQSTLLDFLLPEEVAAHADELAAELGHAVSPETLFAEYVRHGLISAREWTYRRKDGTRFPVSLSIT
PLKGGDGGLAGTLAAAMDITERKWAEEEAHRAKQAAEAANQAKSSFLANMSHELRTPLNAIIGYSEMLQEEMEDLGQDDL
IPDLAKIHSAGRHLLTLINDVLDISKIEAGKMDLFVEAFEIAPMVADVVATISPLIQKNGNTLVVDGAGEIGAMEADLTK
VRQTLFNLLSNASKFTSDGTITLSTRRQGEWIEFAVADTGIGMAPAELDRLFQAFSQADASTTRKFGGTGLGLAISRTFC
RMMGGDIAVASEPGRGTTFTVRLPAVSASPKAARPAGAIESGPELPLVLVIDDDAVARDLLGRFLDENGFRARFAADGPL
GLEMARALRPAAITLDVMMPGMDGWSVLTALKTDPELAAIPVIMVSVVENQALGYALGAHHFMSKPIDRDQLAEVLSRFK
EAGPIERILVVEDDHTNREMLRRMLVKEGWSVIEAANGRIALERVAESRPDLILLDLMMPEMDGFEFVSELRRHSAWHAI
PVVVLTAKDIGQDDRDRLAGGVQKVLQKGAADNETLLTELKRLVTPG

Sequences:

>Translated_687_residues
MTDRIAELVAENALLRGEIRVAREAAEITARLVVKQFEETERLLDRFQSANAQRQAVLDAALQMSIIATDMNGKVLLFNR
GAETLLGYASDEVVGQSTLLDFLLPEEVAAHADELAAELGHAVSPETLFAEYVRHGLISAREWTYRRKDGTRFPVSLSIT
PLKGGDGGLAGTLAAAMDITERKWAEEEAHRAKQAAEAANQAKSSFLANMSHELRTPLNAIIGYSEMLQEEMEDLGQDDL
IPDLAKIHSAGRHLLTLINDVLDISKIEAGKMDLFVEAFEIAPMVADVVATISPLIQKNGNTLVVDGAGEIGAMEADLTK
VRQTLFNLLSNASKFTSDGTITLSTRRQGEWIEFAVADTGIGMAPAELDRLFQAFSQADASTTRKFGGTGLGLAISRTFC
RMMGGDIAVASEPGRGTTFTVRLPAVSASPKAARPAGAIESGPELPLVLVIDDDAVARDLLGRFLDENGFRARFAADGPL
GLEMARALRPAAITLDVMMPGMDGWSVLTALKTDPELAAIPVIMVSVVENQALGYALGAHHFMSKPIDRDQLAEVLSRFK
EAGPIERILVVEDDHTNREMLRRMLVKEGWSVIEAANGRIALERVAESRPDLILLDLMMPEMDGFEFVSELRRHSAWHAI
PVVVLTAKDIGQDDRDRLAGGVQKVLQKGAADNETLLTELKRLVTPG
>Mature_686_residues
TDRIAELVAENALLRGEIRVAREAAEITARLVVKQFEETERLLDRFQSANAQRQAVLDAALQMSIIATDMNGKVLLFNRG
AETLLGYASDEVVGQSTLLDFLLPEEVAAHADELAAELGHAVSPETLFAEYVRHGLISAREWTYRRKDGTRFPVSLSITP
LKGGDGGLAGTLAAAMDITERKWAEEEAHRAKQAAEAANQAKSSFLANMSHELRTPLNAIIGYSEMLQEEMEDLGQDDLI
PDLAKIHSAGRHLLTLINDVLDISKIEAGKMDLFVEAFEIAPMVADVVATISPLIQKNGNTLVVDGAGEIGAMEADLTKV
RQTLFNLLSNASKFTSDGTITLSTRRQGEWIEFAVADTGIGMAPAELDRLFQAFSQADASTTRKFGGTGLGLAISRTFCR
MMGGDIAVASEPGRGTTFTVRLPAVSASPKAARPAGAIESGPELPLVLVIDDDAVARDLLGRFLDENGFRARFAADGPLG
LEMARALRPAAITLDVMMPGMDGWSVLTALKTDPELAAIPVIMVSVVENQALGYALGAHHFMSKPIDRDQLAEVLSRFKE
AGPIERILVVEDDHTNREMLRRMLVKEGWSVIEAANGRIALERVAESRPDLILLDLMMPEMDGFEFVSELRRHSAWHAIP
VVVLTAKDIGQDDRDRLAGGVQKVLQKGAADNETLLTELKRLVTPG

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=503, Percent_Identity=31.4115308151093, Blast_Score=196, Evalue=3e-51,
Organism=Escherichia coli, GI1789149, Length=502, Percent_Identity=29.8804780876494, Blast_Score=180, Evalue=3e-46,
Organism=Escherichia coli, GI48994928, Length=598, Percent_Identity=27.9264214046823, Blast_Score=176, Evalue=4e-45,
Organism=Escherichia coli, GI87081816, Length=380, Percent_Identity=33.6842105263158, Blast_Score=169, Evalue=8e-43,
Organism=Escherichia coli, GI1788713, Length=412, Percent_Identity=28.8834951456311, Blast_Score=154, Evalue=2e-38,
Organism=Escherichia coli, GI1786600, Length=226, Percent_Identity=33.1858407079646, Blast_Score=109, Evalue=8e-25,
Organism=Escherichia coli, GI1788549, Length=367, Percent_Identity=27.5204359673025, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1786912, Length=248, Percent_Identity=27.4193548387097, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1786783, Length=230, Percent_Identity=29.5652173913043, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1788393, Length=230, Percent_Identity=27.3913043478261, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI87082128, Length=228, Percent_Identity=28.5087719298246, Blast_Score=82, Evalue=2e-16,
Organism=Escherichia coli, GI1790436, Length=219, Percent_Identity=27.3972602739726, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1790346, Length=236, Percent_Identity=25.4237288135593, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1786599, Length=118, Percent_Identity=40.6779661016949, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1786911, Length=101, Percent_Identity=39.6039603960396, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1788550, Length=83, Percent_Identity=40.9638554216867, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI1787894, Length=234, Percent_Identity=25.6410256410256, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1790861, Length=223, Percent_Identity=27.3542600896861, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1789808, Length=225, Percent_Identity=25.3333333333333, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 74529; Mature: 74398

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDRIAELVAENALLRGEIRVAREAAEITARLVVKQFEETERLLDRFQSANAQRQAVLDA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
ALQMSIIATDMNGKVLLFNRGAETLLGYASDEVVGQSTLLDFLLPEEVAAHADELAAELG
HHHHEEEEECCCCEEEEEECCHHHHHCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHC
HAVSPETLFAEYVRHGLISAREWTYRRKDGTRFPVSLSITPLKGGDGGLAGTLAAAMDIT
CCCCHHHHHHHHHHHHCCCHHHHCEECCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHH
ERKWAEEEAHRAKQAAEAANQAKSSFLANMSHELRTPLNAIIGYSEMLQEEMEDLGQDDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCHHHHHHHHHHHCCCCCC
IPDLAKIHSAGRHLLTLINDVLDISKIEAGKMDLFVEAFEIAPMVADVVATISPLIQKNG
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NTLVVDGAGEIGAMEADLTKVRQTLFNLLSNASKFTSDGTITLSTRRQGEWIEFAVADTG
CEEEEECCCCCCCCHHHHHHHHHHHHHHHHCHHHCCCCCEEEEEECCCCCEEEEEEECCC
IGMAPAELDRLFQAFSQADASTTRKFGGTGLGLAISRTFCRMMGGDIAVASEPGRGTTFT
CCCCHHHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCEEE
VRLPAVSASPKAARPAGAIESGPELPLVLVIDDDAVARDLLGRFLDENGFRARFAADGPL
EEECCCCCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCCEEEEECCCCC
GLEMARALRPAAITLDVMMPGMDGWSVLTALKTDPELAAIPVIMVSVVENQALGYALGAH
HHHHHHHHCCCEEEEEEEECCCCCHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHH
HFMSKPIDRDQLAEVLSRFKEAGPIERILVVEDDHTNREMLRRMLVKEGWSVIEAANGRI
HHHCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHCCCHHEECCCCCC
ALERVAESRPDLILLDLMMPEMDGFEFVSELRRHSAWHAIPVVVLTAKDIGQDDRDRLAG
HHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCEEEEEEEEEHHCCCCHHHHHHH
GVQKVLQKGAADNETLLTELKRLVTPG
HHHHHHHCCCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
TDRIAELVAENALLRGEIRVAREAAEITARLVVKQFEETERLLDRFQSANAQRQAVLDA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
ALQMSIIATDMNGKVLLFNRGAETLLGYASDEVVGQSTLLDFLLPEEVAAHADELAAELG
HHHHEEEEECCCCEEEEEECCHHHHHCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHC
HAVSPETLFAEYVRHGLISAREWTYRRKDGTRFPVSLSITPLKGGDGGLAGTLAAAMDIT
CCCCHHHHHHHHHHHHCCCHHHHCEECCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHH
ERKWAEEEAHRAKQAAEAANQAKSSFLANMSHELRTPLNAIIGYSEMLQEEMEDLGQDDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCHHHHHHHHHHHCCCCCC
IPDLAKIHSAGRHLLTLINDVLDISKIEAGKMDLFVEAFEIAPMVADVVATISPLIQKNG
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NTLVVDGAGEIGAMEADLTKVRQTLFNLLSNASKFTSDGTITLSTRRQGEWIEFAVADTG
CEEEEECCCCCCCCHHHHHHHHHHHHHHHHCHHHCCCCCEEEEEECCCCCEEEEEEECCC
IGMAPAELDRLFQAFSQADASTTRKFGGTGLGLAISRTFCRMMGGDIAVASEPGRGTTFT
CCCCHHHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCEEE
VRLPAVSASPKAARPAGAIESGPELPLVLVIDDDAVARDLLGRFLDENGFRARFAADGPL
EEECCCCCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCCEEEEECCCCC
GLEMARALRPAAITLDVMMPGMDGWSVLTALKTDPELAAIPVIMVSVVENQALGYALGAH
HHHHHHHHCCCEEEEEEEECCCCCHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHH
HFMSKPIDRDQLAEVLSRFKEAGPIERILVVEDDHTNREMLRRMLVKEGWSVIEAANGRI
HHHCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHCCCHHEECCCCCC
ALERVAESRPDLILLDLMMPEMDGFEFVSELRRHSAWHAIPVVVLTAKDIGQDDRDRLAG
HHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCEEEEEEEEEHHCCCCHHHHHHH
GVQKVLQKGAADNETLLTELKRLVTPG
HHHHHHHCCCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]