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The map label for this gene is manR [H]

Identifier: 82752221

GI number: 82752221

Start: 2659723

End: 2661597

Strand: Direct

Name: manR [H]

Synonym: SAB2515

Alternate gene names: 82752221

Gene position: 2659723-2661597 (Clockwise)

Preceding gene: 82752220

Following gene: 82752222

Centisome position: 96.98

GC content: 30.99

Gene sequence:

>1875_bases
ATGCTTGATAGACACTTAAAACTACTCCAGTTTTTTATTAAAAATCCATCAAAGCACATTAGTTCTAATGAAATTGCTGA
ACATGTCAATGTTTCAAACCGCACAGTTCGCAATGATATCCATGTTATCAATAGCAATTTTATGGATGATATCATCGTAA
GTATTAAATCTAAAGGATATCAATTAAATACATCGCAGTATACCTTAGAAACGATAACTGAACGTTACACACATATTCAA
TCATATAAAGAAAAACTATTATTATCTATGGCGTATCAACTGCTAATGCACAATAAATCACAGACATTGCAACAACTAGA
GCAAGATTATCTATTATCTAAAACTGTGCTCAACGACTATTTCGTTCGAATTCAACAATGGTGTCAAAAATTTAATATCG
CTTTAACAATCAAGAAAAAACAAGGTATTGTGGTCGATGGAACAGATAATGATATCACTAATGCCATCATCCATTTAAAT
CAATTATCATCAGGGCATGTACATGTTGAAGACCTAATTTTAAATGAATTACCTGATTCACACCAAAGAATGATTTCGCA
TATTATACAAGAGACACTTCAACAACATAGTATTGAAACAACTGATATTCAAATACAACAGCTTTTAATTCATCTCATTT
TAATCATTAAACGTAAGCAATCTTTAAGTGAGCTAGACACGTTAAACCACGATTCAAAATTGATATCTCATTCTTGCATT
AAGCAAATCAACGAAAGATTAGGTTATGACTTGAACGAAAAAGTAATCAATATGTTTTCATTCTTTATTGGTTATCATTT
TAATAAACTCGATATTGGCATAGAACGTATATTTATACAAAGTTATATTGATCGCTTAATCGAATTGATGCAGCAACATA
TTCATGTACCTTTCAATGAAGATTCGATTTTACAACAAAATTTATATAATCATTTTAGTAAAGCATATTTACGTATCACT
CAAAACATTTATTTAAACAATCCTTTAGTTATAGAGATTAAAAAACTCTATCCCTTTGTGTTTAACACACTTTTTGAAGC
GATTGATAAATTAGCAATTGATACTGATATAGAGATGAGCGAAGATGAAATTGCCTTTTTAACAATTCATTTTCAAGCTG
CCATCGAGCGTCGTACCAAAACACAATTAAATGTAGTCATTGCTTGTTATTATGGTCTAGGTGTGTCGAATTTTTTAGAA
ACTAAAATAAATAACTTATCCGAAGAGTTGTCAGTGATAAATACGATTAAACTAGAAAATATAACACACTATCACTTTGA
CAATGTAGATTTATTAATAACGACCCATGATATTCCAAAACAAACGCTAAACATACTTCCTAAGCACCTAACGATTATCA
AGGTTGCACCATTATTTTCTGAAGATGACCGTCACAAAATCAGACACGTTGTGAAGCAAAAGCAAAATCCGGTTCAAGCA
CATCATCATATGAACACTGTCAATTTCCTTGTCGTAAATACTGAACAAAAACCACGACATACTGTGCAAATTTTTGAAGA
AGCTCAAAAAATATTACAAGCACATCATGCGATTGTAGAAGGATATATCGAATCAGCTTTAGAGCGTGAGAAATCATCTT
CTACATACATAGGTAATTTTATGGCGATTCCTCATGGAGATCCTGAAAAAGTTTTACAATCACATGTGCTTATTTTTCGC
ACAAAAGATGTTTTTCCTTGGCGACAACACGATGTCAAACTTGTCTTTTTCTTAGCGATTTCGCATAAAGACAAAGCTTT
TACAAAACAAATGATGCAATTAATTGCTAACTTGGATGATGATTCAGTGAACCATTTATGTAGTTTAGATGATCATAGCT
TAAAGCAACAGTTATTTGAATACTTACAAGAATAA

Upstream 100 bases:

>100_bases
TTTAATGTCATTGACGTATGTATAAGCTCTCATGTTTAATAATATTAATACACCTTTAAAAACGCTTACACGGAAAATTT
AGAAAGGAGGTACATGTTAA

Downstream 100 bases:

>100_bases
TTGCCACTAGTAACGGTAATTATTCTTTTTTTAGTATCGAGAATACGCTTACAATATAGAAAAGGAGATGATTTTATGAA
AATTGTAGCTATTACCTCAT

Product: antiterminator transcriptional regulator

Products: NA

Alternate protein names: Putative phosphotransferase enzyme IIB component; Putative PTS system EIIB component; Putative phosphotransferase enzyme IIA component; Putative PTS system EIIA component [H]

Number of amino acids: Translated: 624; Mature: 624

Protein sequence:

>624_residues
MLDRHLKLLQFFIKNPSKHISSNEIAEHVNVSNRTVRNDIHVINSNFMDDIIVSIKSKGYQLNTSQYTLETITERYTHIQ
SYKEKLLLSMAYQLLMHNKSQTLQQLEQDYLLSKTVLNDYFVRIQQWCQKFNIALTIKKKQGIVVDGTDNDITNAIIHLN
QLSSGHVHVEDLILNELPDSHQRMISHIIQETLQQHSIETTDIQIQQLLIHLILIIKRKQSLSELDTLNHDSKLISHSCI
KQINERLGYDLNEKVINMFSFFIGYHFNKLDIGIERIFIQSYIDRLIELMQQHIHVPFNEDSILQQNLYNHFSKAYLRIT
QNIYLNNPLVIEIKKLYPFVFNTLFEAIDKLAIDTDIEMSEDEIAFLTIHFQAAIERRTKTQLNVVIACYYGLGVSNFLE
TKINNLSEELSVINTIKLENITHYHFDNVDLLITTHDIPKQTLNILPKHLTIIKVAPLFSEDDRHKIRHVVKQKQNPVQA
HHHMNTVNFLVVNTEQKPRHTVQIFEEAQKILQAHHAIVEGYIESALEREKSSSTYIGNFMAIPHGDPEKVLQSHVLIFR
TKDVFPWRQHDVKLVFFLAISHKDKAFTKQMMQLIANLDDDSVNHLCSLDDHSLKQQLFEYLQE

Sequences:

>Translated_624_residues
MLDRHLKLLQFFIKNPSKHISSNEIAEHVNVSNRTVRNDIHVINSNFMDDIIVSIKSKGYQLNTSQYTLETITERYTHIQ
SYKEKLLLSMAYQLLMHNKSQTLQQLEQDYLLSKTVLNDYFVRIQQWCQKFNIALTIKKKQGIVVDGTDNDITNAIIHLN
QLSSGHVHVEDLILNELPDSHQRMISHIIQETLQQHSIETTDIQIQQLLIHLILIIKRKQSLSELDTLNHDSKLISHSCI
KQINERLGYDLNEKVINMFSFFIGYHFNKLDIGIERIFIQSYIDRLIELMQQHIHVPFNEDSILQQNLYNHFSKAYLRIT
QNIYLNNPLVIEIKKLYPFVFNTLFEAIDKLAIDTDIEMSEDEIAFLTIHFQAAIERRTKTQLNVVIACYYGLGVSNFLE
TKINNLSEELSVINTIKLENITHYHFDNVDLLITTHDIPKQTLNILPKHLTIIKVAPLFSEDDRHKIRHVVKQKQNPVQA
HHHMNTVNFLVVNTEQKPRHTVQIFEEAQKILQAHHAIVEGYIESALEREKSSSTYIGNFMAIPHGDPEKVLQSHVLIFR
TKDVFPWRQHDVKLVFFLAISHKDKAFTKQMMQLIANLDDDSVNHLCSLDDHSLKQQLFEYLQE
>Mature_624_residues
MLDRHLKLLQFFIKNPSKHISSNEIAEHVNVSNRTVRNDIHVINSNFMDDIIVSIKSKGYQLNTSQYTLETITERYTHIQ
SYKEKLLLSMAYQLLMHNKSQTLQQLEQDYLLSKTVLNDYFVRIQQWCQKFNIALTIKKKQGIVVDGTDNDITNAIIHLN
QLSSGHVHVEDLILNELPDSHQRMISHIIQETLQQHSIETTDIQIQQLLIHLILIIKRKQSLSELDTLNHDSKLISHSCI
KQINERLGYDLNEKVINMFSFFIGYHFNKLDIGIERIFIQSYIDRLIELMQQHIHVPFNEDSILQQNLYNHFSKAYLRIT
QNIYLNNPLVIEIKKLYPFVFNTLFEAIDKLAIDTDIEMSEDEIAFLTIHFQAAIERRTKTQLNVVIACYYGLGVSNFLE
TKINNLSEELSVINTIKLENITHYHFDNVDLLITTHDIPKQTLNILPKHLTIIKVAPLFSEDDRHKIRHVVKQKQNPVQA
HHHMNTVNFLVVNTEQKPRHTVQIFEEAQKILQAHHAIVEGYIESALEREKSSSTYIGNFMAIPHGDPEKVLQSHVLIFR
TKDVFPWRQHDVKLVFFLAISHKDKAFTKQMMQLIANLDDDSVNHLCSLDDHSLKQQLFEYLQE

Specific function: May regulate the expression of the mannose operon [H]

COG id: COG3711

COG function: function code K; Transcriptional antiterminator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIB type-2 domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013196
- InterPro:   IPR007737
- InterPro:   IPR011608
- InterPro:   IPR016152
- InterPro:   IPR002178
- InterPro:   IPR013011
- InterPro:   IPR011991 [H]

Pfam domain/function: PF08279 HTH_11; PF05043 Mga; PF00874 PRD; PF00359 PTS_EIIA_2 [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 72978; Mature: 72978

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: PS00372 PTS_EIIA_TYPE_2_HIS ; PS51094 PTS_EIIA_TYPE_2 ; PS51099 PTS_EIIB_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDRHLKLLQFFIKNPSKHISSNEIAEHVNVSNRTVRNDIHVINSNFMDDIIVSIKSKGY
CCCHHHHHHHHHHHCCHHCCCHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHCCCE
QLNTSQYTLETITERYTHIQSYKEKLLLSMAYQLLMHNKSQTLQQLEQDYLLSKTVLNDY
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
FVRIQQWCQKFNIALTIKKKQGIVVDGTDNDITNAIIHLNQLSSGHVHVEDLILNELPDS
HHHHHHHHHHCCEEEEEEECCCEEEECCCCCHHHHHHEEECCCCCCEEHHHHHHHHCCCH
HQRMISHIIQETLQQHSIETTDIQIQQLLIHLILIIKRKQSLSELDTLNHDSKLISHSCI
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
KQINERLGYDLNEKVINMFSFFIGYHFNKLDIGIERIFIQSYIDRLIELMQQHIHVPFNE
HHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
DSILQQNLYNHFSKAYLRITQNIYLNNPLVIEIKKLYPFVFNTLFEAIDKLAIDTDIEMS
CHHHHHHHHHHHHHHHHHHHHHEEECCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCC
EDEIAFLTIHFQAAIERRTKTQLNVVIACYYGLGVSNFLETKINNLSEELSVINTIKLEN
CCCEEEEEEEHHHHHHHHHHHHHHEEEEEEHHCCHHHHHHHHHHHHHHHHHHHHHEEECC
ITHYHFDNVDLLITTHDIPKQTLNILPKHLTIIKVAPLFSEDDRHKIRHVVKQKQNPVQA
CEEEECCCEEEEEEECCCCHHHHHHCHHHEEEEEEECCCCCCHHHHHHHHHHHCCCCHHH
HHHMNTVNFLVVNTEQKPRHTVQIFEEAQKILQAHHAIVEGYIESALEREKSSSTYIGNF
HHCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
MAIPHGDPEKVLQSHVLIFRTKDVFPWRQHDVKLVFFLAISHKDKAFTKQMMQLIANLDD
EECCCCCHHHHHHCCEEEEEECCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHCCCC
DSVNHLCSLDDHSLKQQLFEYLQE
CHHHHHCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MLDRHLKLLQFFIKNPSKHISSNEIAEHVNVSNRTVRNDIHVINSNFMDDIIVSIKSKGY
CCCHHHHHHHHHHHCCHHCCCHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHCCCE
QLNTSQYTLETITERYTHIQSYKEKLLLSMAYQLLMHNKSQTLQQLEQDYLLSKTVLNDY
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
FVRIQQWCQKFNIALTIKKKQGIVVDGTDNDITNAIIHLNQLSSGHVHVEDLILNELPDS
HHHHHHHHHHCCEEEEEEECCCEEEECCCCCHHHHHHEEECCCCCCEEHHHHHHHHCCCH
HQRMISHIIQETLQQHSIETTDIQIQQLLIHLILIIKRKQSLSELDTLNHDSKLISHSCI
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
KQINERLGYDLNEKVINMFSFFIGYHFNKLDIGIERIFIQSYIDRLIELMQQHIHVPFNE
HHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
DSILQQNLYNHFSKAYLRITQNIYLNNPLVIEIKKLYPFVFNTLFEAIDKLAIDTDIEMS
CHHHHHHHHHHHHHHHHHHHHHEEECCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCC
EDEIAFLTIHFQAAIERRTKTQLNVVIACYYGLGVSNFLETKINNLSEELSVINTIKLEN
CCCEEEEEEEHHHHHHHHHHHHHHEEEEEEHHCCHHHHHHHHHHHHHHHHHHHHHEEECC
ITHYHFDNVDLLITTHDIPKQTLNILPKHLTIIKVAPLFSEDDRHKIRHVVKQKQNPVQA
CEEEECCCEEEEEEECCCCHHHHHHCHHHEEEEEEECCCCCCHHHHHHHHHHHCCCCHHH
HHHMNTVNFLVVNTEQKPRHTVQIFEEAQKILQAHHAIVEGYIESALEREKSSSTYIGNF
HHCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
MAIPHGDPEKVLQSHVLIFRTKDVFPWRQHDVKLVFFLAISHKDKAFTKQMMQLIANLDD
EECCCCCHHHHHHCCEEEEEECCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHCCCC
DSVNHLCSLDDHSLKQQLFEYLQE
CHHHHHCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]