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The map label for this gene is galM [H]

Identifier: 82751931

GI number: 82751931

Start: 2347043

End: 2348062

Strand: Reverse

Name: galM [H]

Synonym: SAB2215c

Alternate gene names: 82751931

Gene position: 2348062-2347043 (Counterclockwise)

Preceding gene: 82751932

Following gene: 82751929

Centisome position: 85.62

GC content: 31.37

Gene sequence:

>1020_bases
ATGATAGTTGAAGTTGAGCACCAAAGACAAGGTGTAGATTTAATCAAAATTGATAATGATGAAACTAAAATTATTTTTAC
GAATTATGGAGCAAGAGTAGTGTCTTGGAAATATCATGATAATAATATTGTTCTTGGAAATGTTGTTGAAGCGGATGAAT
TTTATCATAGTAATCCTTTTAAATTGGGTGCTTCTATAGGAAGATATAGCGGTAGAATTCATAATGCTAAATTTAAGTTG
AAAGGTAAAGAATATCAGTTAGAAAAAAACAACGGCGAACATCATTTACATGGTGGATGTCATGGTTTGGACAATAAGTT
ATTTGATTATGAAATTAGAAATGAAATTGCTCAAATTAAAGTGATATTTAAGACGGTGTTGAAATCAGCTGATGATCATT
TCCCGGGTGATATCGATGTGACGATTACACATATTTATGATGCGGATCACCAATGGTCGATTGAATACGAAGCAGTTGCA
TCAGAAGACACATTGTTTAGTCCTACGAATCATGTGTACTTCAATTTGAATCGAGATAATAATGTCGTTGATAATCATCG
CATTTCAAGTAATCAATTAGATATGTATGTATTAGATGATCGAAATATTGTTACAGGCGATATTCTAGATTTACATGAAG
TGTTTGAAGATAACAAGATAAAATTGAGTGATATTTTTACATCACAACATGTGCAATTAAGCCAACAAATGACACGTTTT
GGTGGTCTTGATCACCCATTTACAGTTGGTGAACATAAAATGTATGTTGAAAATCATGAATTTATGTTAGAGGTCGATAC
AGATATGCCTCATGTTGTATTCTTTACTTTTAATCAGCCTGATGAGTGGGATAGTCCATTTAATATTTATAAACCACATT
CTGGCTTTACATTAGAAACACAATTCTTACCAAATGATATTAATTTATATGGAGAAAAAGCACCGTCAATTTTAAAAGCT
GGTGAAGTGTTCAATTCGAAAACAAGTTTCCGTATCGAAGAAAAAGTAGAAAATGATTAA

Upstream 100 bases:

>100_bases
AATATGATGTTATCGGTGCAATCATTTGTATTGTAGGTGTTTTAGTAATGTTGCTACCCAGCAGAGCTTGAACACTTGTG
GTTAGAAGGGAGAAGTAAAA

Downstream 100 bases:

>100_bases
AAGTATCGGTATTTATATAATATTTATGTTATTTGGCGGAATTTTGAATAGGTTATCAAGAATCGTATCAAATGAAGTGA
CATCATTAATATACAGTTTG

Product: epimerase

Products: NA

Alternate protein names: Galactose mutarotase; Type-1 mutarotase [H]

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MIVEVEHQRQGVDLIKIDNDETKIIFTNYGARVVSWKYHDNNIVLGNVVEADEFYHSNPFKLGASIGRYSGRIHNAKFKL
KGKEYQLEKNNGEHHLHGGCHGLDNKLFDYEIRNEIAQIKVIFKTVLKSADDHFPGDIDVTITHIYDADHQWSIEYEAVA
SEDTLFSPTNHVYFNLNRDNNVVDNHRISSNQLDMYVLDDRNIVTGDILDLHEVFEDNKIKLSDIFTSQHVQLSQQMTRF
GGLDHPFTVGEHKMYVENHEFMLEVDTDMPHVVFFTFNQPDEWDSPFNIYKPHSGFTLETQFLPNDINLYGEKAPSILKA
GEVFNSKTSFRIEEKVEND

Sequences:

>Translated_339_residues
MIVEVEHQRQGVDLIKIDNDETKIIFTNYGARVVSWKYHDNNIVLGNVVEADEFYHSNPFKLGASIGRYSGRIHNAKFKL
KGKEYQLEKNNGEHHLHGGCHGLDNKLFDYEIRNEIAQIKVIFKTVLKSADDHFPGDIDVTITHIYDADHQWSIEYEAVA
SEDTLFSPTNHVYFNLNRDNNVVDNHRISSNQLDMYVLDDRNIVTGDILDLHEVFEDNKIKLSDIFTSQHVQLSQQMTRF
GGLDHPFTVGEHKMYVENHEFMLEVDTDMPHVVFFTFNQPDEWDSPFNIYKPHSGFTLETQFLPNDINLYGEKAPSILKA
GEVFNSKTSFRIEEKVEND
>Mature_339_residues
MIVEVEHQRQGVDLIKIDNDETKIIFTNYGARVVSWKYHDNNIVLGNVVEADEFYHSNPFKLGASIGRYSGRIHNAKFKL
KGKEYQLEKNNGEHHLHGGCHGLDNKLFDYEIRNEIAQIKVIFKTVLKSADDHFPGDIDVTITHIYDADHQWSIEYEAVA
SEDTLFSPTNHVYFNLNRDNNVVDNHRISSNQLDMYVLDDRNIVTGDILDLHEVFEDNKIKLSDIFTSQHVQLSQQMTRF
GGLDHPFTVGEHKMYVENHEFMLEVDTDMPHVVFFTFNQPDEWDSPFNIYKPHSGFTLETQFLPNDINLYGEKAPSILKA
GEVFNSKTSFRIEEKVEND

Specific function: Mutarotase converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose [H]

COG id: COG2017

COG function: function code G; Galactose mutarotase and related enzymes

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldose epimerase family [H]

Homologues:

Organism=Homo sapiens, GI20270355, Length=337, Percent_Identity=27.299703264095, Blast_Score=109, Evalue=4e-24,
Organism=Escherichia coli, GI1786971, Length=349, Percent_Identity=26.3610315186246, Blast_Score=104, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI17557428, Length=185, Percent_Identity=30.8108108108108, Blast_Score=82, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI115533334, Length=185, Percent_Identity=30.8108108108108, Blast_Score=82, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6322004, Length=339, Percent_Identity=25.6637168141593, Blast_Score=92, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6319493, Length=321, Percent_Identity=28.0373831775701, Blast_Score=83, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6324399, Length=339, Percent_Identity=26.2536873156342, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24659048, Length=324, Percent_Identity=28.0864197530864, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24583720, Length=269, Percent_Identity=24.5353159851301, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24668278, Length=262, Percent_Identity=23.6641221374046, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24668282, Length=332, Percent_Identity=23.7951807228916, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018052
- InterPro:   IPR013458
- InterPro:   IPR008183
- InterPro:   IPR015443
- InterPro:   IPR011013
- InterPro:   IPR014718 [H]

Pfam domain/function: PF01263 Aldose_epim [H]

EC number: =5.1.3.3 [H]

Molecular weight: Translated: 39282; Mature: 39282

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS00545 ALDOSE_1_EPIMERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVEVEHQRQGVDLIKIDNDETKIIFTNYGARVVSWKYHDNNIVLGNVVEADEFYHSNPF
CEEEEECHHCCCEEEEECCCCEEEEEEECCCEEEEEEEECCCEEEEEEEEHHHHHCCCCE
KLGASIGRYSGRIHNAKFKLKGKEYQLEKNNGEHHLHGGCHGLDNKLFDYEIRNEIAQIK
EECCCHHHCCCEEECEEEEECCCEEEEECCCCCEEECCCCCCCCCCEECHHHHHHHHHHH
VIFKTVLKSADDHFPGDIDVTITHIYDADHQWSIEYEAVASEDTLFSPTNHVYFNLNRDN
HHHHHHHHCCCCCCCCCEEEEEEEEECCCCEEEEEEEEECCCCCEECCCCEEEEEECCCC
NVVDNHRISSNQLDMYVLDDRNIVTGDILDLHEVFEDNKIKLSDIFTSQHVQLSQQMTRF
CCCCCCCCCCCCEEEEEECCCCEEECCHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHH
GGLDHPFTVGEHKMYVENHEFMLEVDTDMPHVVFFTFNQPDEWDSPFNIYKPHSGFTLET
CCCCCCEECCCEEEEEECCEEEEEECCCCCEEEEEECCCCCCCCCCCEEECCCCCCEEEE
QFLPNDINLYGEKAPSILKAGEVFNSKTSFRIEEKVEND
EECCCCCEECCCCCCCHHHHHHHHCCCCCEEECCCCCCC
>Mature Secondary Structure
MIVEVEHQRQGVDLIKIDNDETKIIFTNYGARVVSWKYHDNNIVLGNVVEADEFYHSNPF
CEEEEECHHCCCEEEEECCCCEEEEEEECCCEEEEEEEECCCEEEEEEEEHHHHHCCCCE
KLGASIGRYSGRIHNAKFKLKGKEYQLEKNNGEHHLHGGCHGLDNKLFDYEIRNEIAQIK
EECCCHHHCCCEEECEEEEECCCEEEEECCCCCEEECCCCCCCCCCEECHHHHHHHHHHH
VIFKTVLKSADDHFPGDIDVTITHIYDADHQWSIEYEAVASEDTLFSPTNHVYFNLNRDN
HHHHHHHHCCCCCCCCCEEEEEEEEECCCCEEEEEEEEECCCCCEECCCCEEEEEECCCC
NVVDNHRISSNQLDMYVLDDRNIVTGDILDLHEVFEDNKIKLSDIFTSQHVQLSQQMTRF
CCCCCCCCCCCCEEEEEECCCCEEECCHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHH
GGLDHPFTVGEHKMYVENHEFMLEVDTDMPHVVFFTFNQPDEWDSPFNIYKPHSGFTLET
CCCCCCEECCCEEEEEECCEEEEEECCCCCEEEEEECCCCCCCCCCCEEECCCCCCEEEE
QFLPNDINLYGEKAPSILKAGEVFNSKTSFRIEEKVEND
EECCCCCEECCCCCCCHHHHHHHHCCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 1282642 [H]