Click here to switch to the map view.

The map label for this gene is dapE [H]

Identifier: 82751598

GI number: 82751598

Start: 2014391

End: 2015614

Strand: Direct

Name: dapE [H]

Synonym: SAB1877

Alternate gene names: 82751598

Gene position: 2014391-2015614 (Clockwise)

Preceding gene: 82751595

Following gene: 82751603

Centisome position: 73.45

GC content: 33.33

Gene sequence:

>1224_bases
ATGACAACTTTTAGTGAAAATGAAAAAATTCAATTACTAGCAGATATTGTTGAACTACAAACTGAAAATAATAATGAAAT
AGACGTTTGTAATTATTTAAAAGATTTATTCGACAAGTACGATATTAAATCTGAAATTTTGAAAGTTAATGAACACCGCG
CCAATATCGTTGCAGAAATCGGTAACGGCTCACCTATACTCGTATTGAGTGGTCATATGGATGTTGTTGATGCAGGAAAT
CAAGATAATTGGACTTATCCCCCTTTTCAACTCACAGAAAAAGATGGCAAATTATACGGTCGAGGCACAACGGATATGAA
AGGCGGTCTGATGGCTTTGGTCATCACACTCATTGAATTAAAAGAACAAAATCAATTGCCTCAAGGAACGATAAGATTAC
TAGCTACTGCTGGCGAAGAGAAAGAACAAGAAGGTGCCAAATTATTGGCTGATAAAGGCTATTTAGACGATGTAGATGGC
TTAATTATTGCTGAACCAACTGGATCTGGAATTTATTATGCACATAAAGGGTCTATGTCATGTAAAGTAACTGCAATTGG
TAAAGCTGTCCATAGCTCAGTTCCATTTATTGGTGACAATGCAATTGATACACTGCTTGAATTTTATAATCAATTTAAAG
AAAAATATTCAGAGCTTAAAAAACATGATACTAAACATGAATTAGATGTTGCACCCATGTTCAAATCATTGATAGGAAAA
GAAATTTCTGAAGAGGATGCAAATTATGCATCTGGTCTTACAGCTGTATGTTCGATTATAAATGGCGGCAAACAATTTAA
CTCTGTACCAGATGAAGCTTCACTTGAATTTAACGTAAGACCAGTTCCTGAGTATGATAACGACTTTATAGAATCGTTTT
TCCAAAATATCATTAATAATGTGGATAGCAATAAGCTTTCACTCGATATTCCAAGCAATCACCGACCTGTAACAAGCGAT
AAAAATAGCAAATTAATTACTACGATTAAAGATGTAGCTTCTAGTTATGTAAACAAAGACGATATATTTGTTTCGGCGCT
TGTAGGTGCAACAGATGCCTCTAGTTTCTTAGGTGATAATAAGGACAATGTTGATTTAGCCATTTTTGGACCAGGTAATC
CATTAATGGCACATCAAATCGATGAATATATTGAAAAAGATATGTATCTGAAATATATTGATATTTTTAAAGAGGCTTCC
ATTCAATATTTAAAAGAAAAATAA

Upstream 100 bases:

>100_bases
AAATCAAATAACACACCACTTTCTGCATTTTAAATTATGTTTAAGAATAAAAATTATGTTTATATAAATATATATACTAC
TTTGAAAAGGTGTGAGCTTA

Downstream 100 bases:

>100_bases
GAACGATGCTGTCAGCTACCCTATTCGCGTGCTGGCAGTTTTTTATTGCGAATTTTAAGTTGATAGAAATAGCGATGAAT
ATTGTTTGAATGTAAATATT

Product: succinyl-diaminopimelate desuccinylase

Products: NA

Alternate protein names: SDAP desuccinylase [H]

Number of amino acids: Translated: 407; Mature: 406

Protein sequence:

>407_residues
MTTFSENEKIQLLADIVELQTENNNEIDVCNYLKDLFDKYDIKSEILKVNEHRANIVAEIGNGSPILVLSGHMDVVDAGN
QDNWTYPPFQLTEKDGKLYGRGTTDMKGGLMALVITLIELKEQNQLPQGTIRLLATAGEEKEQEGAKLLADKGYLDDVDG
LIIAEPTGSGIYYAHKGSMSCKVTAIGKAVHSSVPFIGDNAIDTLLEFYNQFKEKYSELKKHDTKHELDVAPMFKSLIGK
EISEEDANYASGLTAVCSIINGGKQFNSVPDEASLEFNVRPVPEYDNDFIESFFQNIINNVDSNKLSLDIPSNHRPVTSD
KNSKLITTIKDVASSYVNKDDIFVSALVGATDASSFLGDNKDNVDLAIFGPGNPLMAHQIDEYIEKDMYLKYIDIFKEAS
IQYLKEK

Sequences:

>Translated_407_residues
MTTFSENEKIQLLADIVELQTENNNEIDVCNYLKDLFDKYDIKSEILKVNEHRANIVAEIGNGSPILVLSGHMDVVDAGN
QDNWTYPPFQLTEKDGKLYGRGTTDMKGGLMALVITLIELKEQNQLPQGTIRLLATAGEEKEQEGAKLLADKGYLDDVDG
LIIAEPTGSGIYYAHKGSMSCKVTAIGKAVHSSVPFIGDNAIDTLLEFYNQFKEKYSELKKHDTKHELDVAPMFKSLIGK
EISEEDANYASGLTAVCSIINGGKQFNSVPDEASLEFNVRPVPEYDNDFIESFFQNIINNVDSNKLSLDIPSNHRPVTSD
KNSKLITTIKDVASSYVNKDDIFVSALVGATDASSFLGDNKDNVDLAIFGPGNPLMAHQIDEYIEKDMYLKYIDIFKEAS
IQYLKEK
>Mature_406_residues
TTFSENEKIQLLADIVELQTENNNEIDVCNYLKDLFDKYDIKSEILKVNEHRANIVAEIGNGSPILVLSGHMDVVDAGNQ
DNWTYPPFQLTEKDGKLYGRGTTDMKGGLMALVITLIELKEQNQLPQGTIRLLATAGEEKEQEGAKLLADKGYLDDVDGL
IIAEPTGSGIYYAHKGSMSCKVTAIGKAVHSSVPFIGDNAIDTLLEFYNQFKEKYSELKKHDTKHELDVAPMFKSLIGKE
ISEEDANYASGLTAVCSIINGGKQFNSVPDEASLEFNVRPVPEYDNDFIESFFQNIINNVDSNKLSLDIPSNHRPVTSDK
NSKLITTIKDVASSYVNKDDIFVSALVGATDASSFLGDNKDNVDLAIFGPGNPLMAHQIDEYIEKDMYLKYIDIFKEASI
QYLKEK

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family [H]

Homologues:

Organism=Escherichia coli, GI1790395, Length=375, Percent_Identity=27.4666666666667, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1788816, Length=246, Percent_Identity=25.609756097561, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1789236, Length=215, Percent_Identity=26.5116279069767, Blast_Score=81, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001261
- InterPro:   IPR010182
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.18 [H]

Molecular weight: Translated: 45177; Mature: 45046

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: PS00759 ARGE_DAPE_CPG2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTFSENEKIQLLADIVELQTENNNEIDVCNYLKDLFDKYDIKSEILKVNEHRANIVAEI
CCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHCCCCEEEEEE
GNGSPILVLSGHMDVVDAGNQDNWTYPPFQLTEKDGKLYGRGTTDMKGGLMALVITLIEL
CCCCEEEEEECCEEEEECCCCCCCCCCCCEEECCCCEEEECCCCCHHCHHHHHHHHHHHH
KEQNQLPQGTIRLLATAGEEKEQEGAKLLADKGYLDDVDGLIIAEPTGSGIYYAHKGSMS
HHHCCCCHHHEEEEECCCCHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCEEEEECCCCE
CKVTAIGKAVHSSVPFIGDNAIDTLLEFYNQFKEKYSELKKHDTKHELDVAPMFKSLIGK
EEEEEHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHCC
EISEEDANYASGLTAVCSIINGGKQFNSVPDEASLEFNVRPVPEYDNDFIESFFQNIINN
HHHHHCCHHHHHHHHHHHHHCCCHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCC
VDSNKLSLDIPSNHRPVTSDKNSKLITTIKDVASSYVNKDDIFVSALVGATDASSFLGDN
CCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHEEEHHHCCCCHHHHHCCC
KDNVDLAIFGPGNPLMAHQIDEYIEKDMYLKYIDIFKEASIQYLKEK
CCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TTFSENEKIQLLADIVELQTENNNEIDVCNYLKDLFDKYDIKSEILKVNEHRANIVAEI
CCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHCCCCEEEEEE
GNGSPILVLSGHMDVVDAGNQDNWTYPPFQLTEKDGKLYGRGTTDMKGGLMALVITLIEL
CCCCEEEEEECCEEEEECCCCCCCCCCCCEEECCCCEEEECCCCCHHCHHHHHHHHHHHH
KEQNQLPQGTIRLLATAGEEKEQEGAKLLADKGYLDDVDGLIIAEPTGSGIYYAHKGSMS
HHHCCCCHHHEEEEECCCCHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCEEEEECCCCE
CKVTAIGKAVHSSVPFIGDNAIDTLLEFYNQFKEKYSELKKHDTKHELDVAPMFKSLIGK
EEEEEHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHCC
EISEEDANYASGLTAVCSIINGGKQFNSVPDEASLEFNVRPVPEYDNDFIESFFQNIINN
HHHHHCCHHHHHHHHHHHHHCCCHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCC
VDSNKLSLDIPSNHRPVTSDKNSKLITTIKDVASSYVNKDDIFVSALVGATDASSFLGDN
CCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHEEEHHHCCCCHHHHHCCC
KDNVDLAIFGPGNPLMAHQIDEYIEKDMYLKYIDIFKEASIQYLKEK
CCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11418146 [H]