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The map label for this gene is pfbA [H]

Identifier: 82751575

GI number: 82751575

Start: 1991074

End: 1992171

Strand: Reverse

Name: pfbA [H]

Synonym: SAB1854c

Alternate gene names: 82751575

Gene position: 1992171-1991074 (Counterclockwise)

Preceding gene: 82751579

Following gene: 82751574

Centisome position: 72.64

GC content: 32.6

Gene sequence:

>1098_bases
ATGTATATCAATATGAAAGATTATGGGTTAACAGGCATAAACAAAACTAAAGATACTCGAGCAATACAACGTGCGTTAAA
TCATGGAAGATGTAAACCAACGACAGTTTATATACCAAAAGGGACGTATGATATTTGCAAACCATTAACGATATATGGCA
ATACAACACTTTTGTTAGATAATGAAACTATTTTACGCCGATGTCATTCGGGTCCTTTATTAAAAAATGGTCATCGCTTT
GGTTTTTATCGTGGTTATAATGGACACAGTCATATTCATATTAAAGGCGGCAAGTTTGATATGAATGGCATATCGTATCC
TTATAACAATACAGCTATGTGCATTGGGCATGCTGAAGATATTCAATTAATAGGTGTAACCATTAAGAATGTAGTGAGTG
GTCATGCAATTGATGCTTGTGGGATTAATGGACTCTATATTAAAAACTGTTCATTTGAAGGATTCATAGACTATAGTGGC
GAACGCTTTTATTCTGAAGCAATACAATTAGACATTCAAGTACCTGGTGCTTTTCCAAAATTCGGAACGACAGATGGCAC
GATAACGAAAAATGTCATTATCGAAGATTGTTATTTTGGACCTTCAGAATTGCCCGAAATGGGAAGTTGGAATCGAGCTA
TTGGCTCACATGCAAGTAGACATAATCGTTACTATGAGAATATTCATATTAGAAATAATATATTTGAAGATATACAAGGT
TATGCATTAACTCCCTTGAAGTATAAAGATGCTTTCATTATTAATAATAAGTTTATTAACTGTGAGGGTGGTATTAGATA
TTTAGGAGTTAGAGATGGTAAAAACGCTGCAGATGTGATGACAGGAAAAGACTTAGGTTCCCAAGCAGGAATAAATATGA
ATATAATTGGAAATGAATTTAAAGGATCAATGTCTAAAGATGCGATACATGTACGTAATTATAATAATGTTAAACATAAA
GATGTATTAATCGTTGGGAATACATTCAAAAATTCGACTCAATCAATTCATTTGGAAGATATTGATACAGTGTTTTTAAG
TCCTATTGAAGCGGGTATTCAAGTTACTACAATCAATGTAGATGAAATAAAAAAGTAA

Upstream 100 bases:

>100_bases
CGAGATTTATGACTATCTGCTAAATCAACCTAACACGATTATAATTTGAATAATTGGTTAAAATATGAGTAATTAGAAAA
TAGACAAAGGATGACGATTT

Downstream 100 bases:

>100_bases
AAAGTTTCGCATGACATTAGGATTAAGAATAGTAGATATTTTTTTGAAAGCGCATTCATAAAACGGTATAAATATGCTAT
AATAAATCCAATTATCTGAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MYINMKDYGLTGINKTKDTRAIQRALNHGRCKPTTVYIPKGTYDICKPLTIYGNTTLLLDNETILRRCHSGPLLKNGHRF
GFYRGYNGHSHIHIKGGKFDMNGISYPYNNTAMCIGHAEDIQLIGVTIKNVVSGHAIDACGINGLYIKNCSFEGFIDYSG
ERFYSEAIQLDIQVPGAFPKFGTTDGTITKNVIIEDCYFGPSELPEMGSWNRAIGSHASRHNRYYENIHIRNNIFEDIQG
YALTPLKYKDAFIINNKFINCEGGIRYLGVRDGKNAADVMTGKDLGSQAGINMNIIGNEFKGSMSKDAIHVRNYNNVKHK
DVLIVGNTFKNSTQSIHLEDIDTVFLSPIEAGIQVTTINVDEIKK

Sequences:

>Translated_365_residues
MYINMKDYGLTGINKTKDTRAIQRALNHGRCKPTTVYIPKGTYDICKPLTIYGNTTLLLDNETILRRCHSGPLLKNGHRF
GFYRGYNGHSHIHIKGGKFDMNGISYPYNNTAMCIGHAEDIQLIGVTIKNVVSGHAIDACGINGLYIKNCSFEGFIDYSG
ERFYSEAIQLDIQVPGAFPKFGTTDGTITKNVIIEDCYFGPSELPEMGSWNRAIGSHASRHNRYYENIHIRNNIFEDIQG
YALTPLKYKDAFIINNKFINCEGGIRYLGVRDGKNAADVMTGKDLGSQAGINMNIIGNEFKGSMSKDAIHVRNYNNVKHK
DVLIVGNTFKNSTQSIHLEDIDTVFLSPIEAGIQVTTINVDEIKK
>Mature_365_residues
MYINMKDYGLTGINKTKDTRAIQRALNHGRCKPTTVYIPKGTYDICKPLTIYGNTTLLLDNETILRRCHSGPLLKNGHRF
GFYRGYNGHSHIHIKGGKFDMNGISYPYNNTAMCIGHAEDIQLIGVTIKNVVSGHAIDACGINGLYIKNCSFEGFIDYSG
ERFYSEAIQLDIQVPGAFPKFGTTDGTITKNVIIEDCYFGPSELPEMGSWNRAIGSHASRHNRYYENIHIRNNIFEDIQG
YALTPLKYKDAFIINNKFINCEGGIRYLGVRDGKNAADVMTGKDLGSQAGINMNIIGNEFKGSMSKDAIHVRNYNNVKHK
DVLIVGNTFKNSTQSIHLEDIDTVFLSPIEAGIQVTTINVDEIKK

Specific function: Acts as a fibronectin-dependent adhesin and invasin. Binds host (in this case human) fibronectin, plasmin, plasminogen, and human serum albumin. Where the bacteria adhere to human cells there is major recruitment of microvilli which seem to fuse to cover

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted, cell wall; Peptidoglycan-anchor (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 5 PbH1 repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005877
- InterPro:   IPR006626
- InterPro:   IPR012334
- InterPro:   IPR011050 [H]

Pfam domain/function: PF04650 YSIRK_signal [H]

EC number: NA

Molecular weight: Translated: 40751; Mature: 40751

Theoretical pI: Translated: 8.37; Mature: 8.37

Prosite motif: PS00435 PEROXIDASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYINMKDYGLTGINKTKDTRAIQRALNHGRCKPTTVYIPKGTYDICKPLTIYGNTTLLLD
CEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCHHHCCCEEEECCEEEEEC
NETILRRCHSGPLLKNGHRFGFYRGYNGHSHIHIKGGKFDMNGISYPYNNTAMCIGHAED
CHHHHHHHCCCCCCCCCCEEEEEECCCCCEEEEEECCEEECCCCCCCCCCEEEEEECCCC
IQLIGVTIKNVVSGHAIDACGINGLYIKNCSFEGFIDYSGERFYSEAIQLDIQVPGAFPK
EEEEEEEHHHHHCCCCEEECCCCCEEEECCCCCEEEECCCCCEEEEEEEEEEECCCCCCC
FGTTDGTITKNVIIEDCYFGPSELPEMGSWNRAIGSHASRHNRYYENIHIRNNIFEDIQG
CCCCCCCEEEEEEEEECCCCHHHCCCCCCCHHHHHCHHHHCCCEEEEEEECCCHHHHCCC
YALTPLKYKDAFIINNKFINCEGGIRYLGVRDGKNAADVMTGKDLGSQAGINMNIIGNEF
CEECCEEECCEEEEECEEEECCCCEEEEEEECCCCHHHEEECCCCCCCCCEEEEEECCCC
KGSMSKDAIHVRNYNNVKHKDVLIVGNTFKNSTQSIHLEDIDTVFLSPIEAGIQVTTINV
CCCCCCCEEEEECCCCCCCCEEEEEECCCCCCCCEEEEECCCEEEECHHHCCEEEEEEEH
DEIKK
HHHCC
>Mature Secondary Structure
MYINMKDYGLTGINKTKDTRAIQRALNHGRCKPTTVYIPKGTYDICKPLTIYGNTTLLLD
CEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCHHHCCCEEEECCEEEEEC
NETILRRCHSGPLLKNGHRFGFYRGYNGHSHIHIKGGKFDMNGISYPYNNTAMCIGHAED
CHHHHHHHCCCCCCCCCCEEEEEECCCCCEEEEEECCEEECCCCCCCCCCEEEEEECCCC
IQLIGVTIKNVVSGHAIDACGINGLYIKNCSFEGFIDYSGERFYSEAIQLDIQVPGAFPK
EEEEEEEHHHHHCCCCEEECCCCCEEEECCCCCEEEECCCCCEEEEEEEEEEECCCCCCC
FGTTDGTITKNVIIEDCYFGPSELPEMGSWNRAIGSHASRHNRYYENIHIRNNIFEDIQG
CCCCCCCEEEEEEEEECCCCHHHCCCCCCCHHHHHCHHHHCCCEEEEEEECCCHHHHCCC
YALTPLKYKDAFIINNKFINCEGGIRYLGVRDGKNAADVMTGKDLGSQAGINMNIIGNEF
CEECCEEECCEEEEECEEEECCCCEEEEEEECCCCHHHEEECCCCCCCCCEEEEEECCCC
KGSMSKDAIHVRNYNNVKHKDVLIVGNTFKNSTQSIHLEDIDTVFLSPIEAGIQVTTINV
CCCCCCCEEEEECCCCCCCCEEEEEECCCCCCCCEEEEECCCEEEECHHHCCEEEEEEEH
DEIKK
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11544234 [H]