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The map label for this gene is sdcS [H]

Identifier: 82751574

GI number: 82751574

Start: 1989306

End: 1990868

Strand: Reverse

Name: sdcS [H]

Synonym: SAB1853c

Alternate gene names: 82751574

Gene position: 1990868-1989306 (Counterclockwise)

Preceding gene: 82751575

Following gene: 82751571

Centisome position: 72.59

GC content: 34.68

Gene sequence:

>1563_bases
ATGGCTTATTTCAATCAACATCAATCAATGATATCGAAAAGGTATTTAACATTCTTTTCAAAATCAAAGAAAAAGAAACC
GTTTAGTGCGGGACAACTTATTGGACTAATATTAGGTCCATTACTTTTCCTATTAACATTATTATTCTTTCATCCACAAG
ACTTACCTTGGGAAGGCGTCTATGTTTTAGCAATTACTTTATGGATTGCGACTTGGTGGATTACTGAAGCAATTCCTATT
GCAGCAACAAGCTTATTACCAATTGTGTTATTACCATTAGGTCACATACTTACACCAGAACAAGTATCATCCGAATATGG
CAATGATATTATCTTTTTGTTTTTAGGTGGATTTATTTTGGCAATTGCAATGGAAAGATGGAATTTACATACGAGAGTAG
CTTTGACTATTATTAATTTAATTGGTGCAAGCACTTCAAAAATATTACTTGGATTCATGGTGGCAACAGGATTCTTATCT
ATGTTTGTATCGAACACTGCGGCTGTAATGATCATGATTCCGATTGGTTTAGCAATTATTAAGGAAGCACATGATTTACA
AGAAGCAAATACGAATCAAACAAGTATTCAAAAGTTTGAAAAATCTCTAGTTTTAGCAATTGGCTATGCAGGTACGATTG
GCGGATTAGGCACACTTATCGGAACGCCGCCGCTAATTATTTTAAAAGGACAATACATGCAACATTTTGGACATGAAATT
AGTTTTGCTAAATGGATGATTGTAGGGATTCCAACGGTCATTGTTTTGTTAGGTATTACTTGGCTCTATTTAAGATATGT
TGCGTTTAGACATGATTTGAAATATTTACCTGGTGGTCAGACGTTAATTAAACAAAAGTTAGACGAGCTTGGCAAAATGA
AGTATGAAGAAAAGGTAGTACAAACTATCTTTGTACTTGCCAGCTTATTATGGATTACAAGAGAGTTTCTTCTGAAAAAA
TGGGAAGTTACGTCATCCGTTGCAGATGGTACGATTGCTATTTTTATATCAATATTATTATTTGTTATTCCAGCTAAAAA
TACTGAAAAACATCGTCGTATCATTGACTGGGAAGTTGCAAAAGAGCTCCCTTGGGGTGTATTAATTTTATTTGGTGGCG
GTTTAGCATTAGCTAAAGGTATATCAGAAAGTGGTTTAGCAAAATGGTTAGGCGAACAGTTGAAATCATTAAATGGTGTT
AGTCCGATTCTTATTGTAATTGTCATAACGATCTTTGTCTTATTTTTAACTGAAGTGACATCTAATACCGCAACTGCAAC
GATGATTTTACCGATTTTAGCAACGTTGTCTGTTGCTGTTGGAGTGCATCCATTACTACTTATGGCACCAGCAGCTATGG
CGGCTAACTGTGCATACATGTTACCAGTAGGGACACCACCGAATGCAATTATCTTTGGTTCGGGTAAAATATCTATCAAA
CAAATGGCATCAGTTGGATTCTGGGTAAACTTAATCAGTGCAATAATTATTATTTTAGTCGTGTATTATGTAATGCCTAT
AGTTTTAGGTATTGATATAAATCAACCACTGCCATTGAAATAG

Upstream 100 bases:

>100_bases
GGGTATTTTGACGGTAATGATAATACAAGATAGACAACTTTCTATACTCTAATATAGTAAGTTGAAGTAGCTTGTCATAA
TCATCATGAGGGGGAAATTT

Downstream 100 bases:

>100_bases
TAATTGCAGATTAGAACGAAAAATAAAAAGTTACATTAGCAATTGCTTGAACGAGTGGTAACGAAACGTATACCGCAGCA
TCGTGTAAAAACAATACAAA

Product: sodium-sulfate symport protein

Products: tartrate [Cytoplasm]; succinate [Periplasm] [C]

Alternate protein names: Na(+)/dicarboxylate symporter [H]

Number of amino acids: Translated: 520; Mature: 519

Protein sequence:

>520_residues
MAYFNQHQSMISKRYLTFFSKSKKKKPFSAGQLIGLILGPLLFLLTLLFFHPQDLPWEGVYVLAITLWIATWWITEAIPI
AATSLLPIVLLPLGHILTPEQVSSEYGNDIIFLFLGGFILAIAMERWNLHTRVALTIINLIGASTSKILLGFMVATGFLS
MFVSNTAAVMIMIPIGLAIIKEAHDLQEANTNQTSIQKFEKSLVLAIGYAGTIGGLGTLIGTPPLIILKGQYMQHFGHEI
SFAKWMIVGIPTVIVLLGITWLYLRYVAFRHDLKYLPGGQTLIKQKLDELGKMKYEEKVVQTIFVLASLLWITREFLLKK
WEVTSSVADGTIAIFISILLFVIPAKNTEKHRRIIDWEVAKELPWGVLILFGGGLALAKGISESGLAKWLGEQLKSLNGV
SPILIVIVITIFVLFLTEVTSNTATATMILPILATLSVAVGVHPLLLMAPAAMAANCAYMLPVGTPPNAIIFGSGKISIK
QMASVGFWVNLISAIIIILVVYYVMPIVLGIDINQPLPLK

Sequences:

>Translated_520_residues
MAYFNQHQSMISKRYLTFFSKSKKKKPFSAGQLIGLILGPLLFLLTLLFFHPQDLPWEGVYVLAITLWIATWWITEAIPI
AATSLLPIVLLPLGHILTPEQVSSEYGNDIIFLFLGGFILAIAMERWNLHTRVALTIINLIGASTSKILLGFMVATGFLS
MFVSNTAAVMIMIPIGLAIIKEAHDLQEANTNQTSIQKFEKSLVLAIGYAGTIGGLGTLIGTPPLIILKGQYMQHFGHEI
SFAKWMIVGIPTVIVLLGITWLYLRYVAFRHDLKYLPGGQTLIKQKLDELGKMKYEEKVVQTIFVLASLLWITREFLLKK
WEVTSSVADGTIAIFISILLFVIPAKNTEKHRRIIDWEVAKELPWGVLILFGGGLALAKGISESGLAKWLGEQLKSLNGV
SPILIVIVITIFVLFLTEVTSNTATATMILPILATLSVAVGVHPLLLMAPAAMAANCAYMLPVGTPPNAIIFGSGKISIK
QMASVGFWVNLISAIIIILVVYYVMPIVLGIDINQPLPLK
>Mature_519_residues
AYFNQHQSMISKRYLTFFSKSKKKKPFSAGQLIGLILGPLLFLLTLLFFHPQDLPWEGVYVLAITLWIATWWITEAIPIA
ATSLLPIVLLPLGHILTPEQVSSEYGNDIIFLFLGGFILAIAMERWNLHTRVALTIINLIGASTSKILLGFMVATGFLSM
FVSNTAAVMIMIPIGLAIIKEAHDLQEANTNQTSIQKFEKSLVLAIGYAGTIGGLGTLIGTPPLIILKGQYMQHFGHEIS
FAKWMIVGIPTVIVLLGITWLYLRYVAFRHDLKYLPGGQTLIKQKLDELGKMKYEEKVVQTIFVLASLLWITREFLLKKW
EVTSSVADGTIAIFISILLFVIPAKNTEKHRRIIDWEVAKELPWGVLILFGGGLALAKGISESGLAKWLGEQLKSLNGVS
PILIVIVITIFVLFLTEVTSNTATATMILPILATLSVAVGVHPLLLMAPAAMAANCAYMLPVGTPPNAIIFGSGKISIKQ
MASVGFWVNLISAIIIILVVYYVMPIVLGIDINQPLPLK

Specific function: Mediates the transport of the dicarboxylates fumarate, malate, and succinate across the cytoplasmic membrane via a Na(+)- electrochemical gradient [H]

COG id: COG0471

COG function: function code P; Di- and tricarboxylate transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SLC13A transporter (TC 2.A.47) family. NADC subfamily [H]

Homologues:

Organism=Homo sapiens, GI29171306, Length=514, Percent_Identity=34.8249027237354, Blast_Score=301, Evalue=1e-81,
Organism=Homo sapiens, GI31377715, Length=561, Percent_Identity=33.8680926916221, Blast_Score=284, Evalue=2e-76,
Organism=Homo sapiens, GI4506979, Length=522, Percent_Identity=36.0153256704981, Blast_Score=280, Evalue=2e-75,
Organism=Homo sapiens, GI58761541, Length=517, Percent_Identity=33.4622823984526, Blast_Score=274, Evalue=1e-73,
Organism=Homo sapiens, GI301069349, Length=500, Percent_Identity=33.2, Blast_Score=263, Evalue=3e-70,
Organism=Homo sapiens, GI301069346, Length=517, Percent_Identity=35.2030947775629, Blast_Score=261, Evalue=1e-69,
Organism=Homo sapiens, GI225637549, Length=572, Percent_Identity=33.3916083916084, Blast_Score=259, Evalue=3e-69,
Organism=Homo sapiens, GI225637552, Length=480, Percent_Identity=35.625, Blast_Score=252, Evalue=8e-67,
Organism=Homo sapiens, GI19923838, Length=544, Percent_Identity=30.3308823529412, Blast_Score=248, Evalue=1e-65,
Organism=Homo sapiens, GI219802232, Length=455, Percent_Identity=34.2857142857143, Blast_Score=246, Evalue=4e-65,
Organism=Homo sapiens, GI301069353, Length=466, Percent_Identity=31.7596566523605, Blast_Score=228, Evalue=1e-59,
Organism=Homo sapiens, GI31795546, Length=347, Percent_Identity=33.4293948126801, Blast_Score=189, Evalue=4e-48,
Organism=Escherichia coli, GI1789444, Length=421, Percent_Identity=24.7030878859857, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1786829, Length=391, Percent_Identity=21.9948849104859, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1786986, Length=434, Percent_Identity=26.9585253456221, Blast_Score=67, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71988385, Length=501, Percent_Identity=35.5289421157685, Blast_Score=280, Evalue=2e-75,
Organism=Caenorhabditis elegans, GI32565804, Length=463, Percent_Identity=34.9892008639309, Blast_Score=265, Evalue=6e-71,
Organism=Caenorhabditis elegans, GI71989118, Length=528, Percent_Identity=33.5227272727273, Blast_Score=252, Evalue=3e-67,
Organism=Caenorhabditis elegans, GI17551790, Length=497, Percent_Identity=28.3702213279678, Blast_Score=220, Evalue=1e-57,
Organism=Caenorhabditis elegans, GI32564681, Length=512, Percent_Identity=28.90625, Blast_Score=216, Evalue=2e-56,
Organism=Saccharomyces cerevisiae, GI6324340, Length=469, Percent_Identity=23.0277185501066, Blast_Score=88, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6322263, Length=477, Percent_Identity=24.1090146750524, Blast_Score=85, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6319885, Length=477, Percent_Identity=23.6897274633124, Blast_Score=78, Evalue=3e-15,
Organism=Drosophila melanogaster, GI281362116, Length=486, Percent_Identity=34.156378600823, Blast_Score=234, Evalue=2e-61,
Organism=Drosophila melanogaster, GI281362114, Length=486, Percent_Identity=33.9506172839506, Blast_Score=227, Evalue=2e-59,
Organism=Drosophila melanogaster, GI281362112, Length=486, Percent_Identity=33.9506172839506, Blast_Score=227, Evalue=2e-59,
Organism=Drosophila melanogaster, GI45551633, Length=522, Percent_Identity=30.4597701149425, Blast_Score=224, Evalue=1e-58,
Organism=Drosophila melanogaster, GI281366409, Length=522, Percent_Identity=30.2681992337165, Blast_Score=224, Evalue=1e-58,
Organism=Drosophila melanogaster, GI17737623, Length=522, Percent_Identity=30.2681992337165, Blast_Score=224, Evalue=1e-58,
Organism=Drosophila melanogaster, GI24666468, Length=522, Percent_Identity=30.2681992337165, Blast_Score=224, Evalue=1e-58,
Organism=Drosophila melanogaster, GI78706796, Length=467, Percent_Identity=30.6209850107066, Blast_Score=164, Evalue=1e-40,
Organism=Drosophila melanogaster, GI78706798, Length=467, Percent_Identity=30.6209850107066, Blast_Score=164, Evalue=1e-40,
Organism=Drosophila melanogaster, GI281364821, Length=452, Percent_Identity=21.6814159292035, Blast_Score=74, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001898 [H]

Pfam domain/function: PF00939 Na_sulph_symp [H]

EC number: NA

Molecular weight: Translated: 57160; Mature: 57028

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYFNQHQSMISKRYLTFFSKSKKKKPFSAGQLIGLILGPLLFLLTLLFFHPQDLPWEGV
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
YVLAITLWIATWWITEAIPIAATSLLPIVLLPLGHILTPEQVSSEYGNDIIFLFLGGFIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCEEHHHHHHHHH
AIAMERWNLHTRVALTIINLIGASTSKILLGFMVATGFLSMFVSNTAAVMIMIPIGLAII
HHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCHHHEEHHHHHHHHHH
KEAHDLQEANTNQTSIQKFEKSLVLAIGYAGTIGGLGTLIGTPPLIILKGQYMQHFGHEI
HHHHHHHHCCCCHHHHHHHHHHHEEEEECCHHHHHHHHHHCCCCEEEEECHHHHHCCCCH
SFAKWMIVGIPTVIVLLGITWLYLRYVAFRHDLKYLPGGQTLIKQKLDELGKMKYEEKVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
QTIFVLASLLWITREFLLKKWEVTSSVADGTIAIFISILLFVIPAKNTEKHRRIIDWEVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
KELPWGVLILFGGGLALAKGISESGLAKWLGEQLKSLNGVSPILIVIVITIFVLFLTEVT
HHCCCEEEEEECCCHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
SNTATATMILPILATLSVAVGVHPLLLMAPAAMAANCAYMLPVGTPPNAIIFGSGKISIK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEECCCCEEHH
QMASVGFWVNLISAIIIILVVYYVMPIVLGIDINQPLPLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
AYFNQHQSMISKRYLTFFSKSKKKKPFSAGQLIGLILGPLLFLLTLLFFHPQDLPWEGV
CCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
YVLAITLWIATWWITEAIPIAATSLLPIVLLPLGHILTPEQVSSEYGNDIIFLFLGGFIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCEEHHHHHHHHH
AIAMERWNLHTRVALTIINLIGASTSKILLGFMVATGFLSMFVSNTAAVMIMIPIGLAII
HHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCHHHEEHHHHHHHHHH
KEAHDLQEANTNQTSIQKFEKSLVLAIGYAGTIGGLGTLIGTPPLIILKGQYMQHFGHEI
HHHHHHHHCCCCHHHHHHHHHHHEEEEECCHHHHHHHHHHCCCCEEEEECHHHHHCCCCH
SFAKWMIVGIPTVIVLLGITWLYLRYVAFRHDLKYLPGGQTLIKQKLDELGKMKYEEKVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
QTIFVLASLLWITREFLLKKWEVTSSVADGTIAIFISILLFVIPAKNTEKHRRIIDWEVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
KELPWGVLILFGGGLALAKGISESGLAKWLGEQLKSLNGVSPILIVIVITIFVLFLTEVT
HHCCCEEEEEECCCHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
SNTATATMILPILATLSVAVGVHPLLLMAPAAMAANCAYMLPVGTPPNAIIFGSGKISIK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEECCCCEEHH
QMASVGFWVNLISAIIIILVVYYVMPIVLGIDINQPLPLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: tartrate [Periplasm]; succinate [Cytoplasm] [C]

Specific reaction: tartrate [Periplasm] + succinate [Cytoplasm] = tartrate [Cytoplasm] + succinate [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA