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The map label for this gene is sun

Identifier: 82750821

GI number: 82750821

Start: 1166829

End: 1168136

Strand: Direct

Name: sun

Synonym: SAB1081

Alternate gene names: 82750821

Gene position: 1166829-1168136 (Clockwise)

Preceding gene: 82750820

Following gene: 82750822

Centisome position: 42.55

GC content: 33.33

Gene sequence:

>1308_bases
ATGATAGAAAACGTGAGAAGTCTTGCTTTTGACACGATTCAAGATATATTAAATGAAGGTGCGTATAGTAACTTGCGTAT
CAATGAAGTGTTGTCAGAAAATGAATTAAATGCAATGGATAAAGCTTTATTTACAGAAATTGTCTACGGAACCGTTAAAA
GAAAATATACGTTAGATTTTTATTTAAAGCCTTTTGTGAAAACAAAGATTAAGGCATGGGTTAGGCAATTATTATGGATG
AGTATTTATCAATATGTTTATTTAGATAAAGTTCCAAATCACGCCATCATTAATGAAGCAGTTGAAATAGCAAAAGAACG
CGGTGGCTATCACAACGGAAATGTCGTAAATGGCATTTTACGAACAATGATGCGTAGTGACTTACCTGATTTTAATGAAA
TTGCAGATCCTAAAAAAAGAATGGCAGTCGAGTATAGTATGCCGAAGTGGATTATAGATCATTGGGCAACACATTATGGT
CTCGAAGAAACTGAAACAATTTTACAGTCATTTTTAGAAACGACATCAACAACTGTGCGTGCCAACCTGACGCGAGCATC
ATTAGATGATATTATTGAAAAGTTGCAAGACGAAGGTTATGACGTTGAAAAAGATCATGACTTACCTTATTGTCTCCATA
TAGGAGGACAACCAATTATTCATTCTCGTTCATTTAAAGATGGATTCGTTTCAATTCAAGATAAAAGCTCAATGTTTGTT
GCACACATTATGAATGTAGACCGACATGATCACGTATTAGATGCATGTAGTGCACCTGGCGGTAAGGCTTGTCACATTGC
TGAAGTTTTAATGCCAGAAGGGCAAGTTGGCGCTTCAGATATACATGATCACAAAATAGACTTAATTAATTTTAATATAA
AAAAATTACGATTAACAAATATTAAAGCTTTTCAACATGATGCGACAAAACCTTATGATAAAACATACGATAAGATACTT
GTTGATGCACCATGTAGCGGATTAGGTGTTATGAGACACAAGCCAGAGATTAAATATACTCAAAGCAAACAACATATTGA
GTCACTAGTTGATTTACAGCTTGAAATATTGGAAAATGTAAAAAACAATGTAAAAATAGGTGGCGAAATCATCTATTCAA
CATGTACAATTGAGCAACTAGAAAATGAAAACGTGATTTATACGTTTTTGAAAAATAATAAAAACTTCGAATTTGAACCG
TTTCAACATCCGATAACTGGAGAGTTGGTCAAAACGTTACAAATCATGCCGCAAGACTTTAATTCAGATGGATTCTTTAT
CACTAAGATAAAAAGAAAGGACAATTAG

Upstream 100 bases:

>100_bases
CTGTTGCAATTAAAGATATGCAATTGGCTGGGAAAAAGAGAATGTTAGCTGCCAATTATTTAAGTGGTGCGCAAAACATA
CTAGTAGGGAAGAAACTTAT

Downstream 100 bases:

>100_bases
GAATGATAACTGCTGAAAAGAAAAAGAAGAATAAATTTCTTCCAAATTTTGACAAGCAATCAATATATTCATTGCGATTT
GACGAAATGCAAAACTGGCT

Product: RNA-binding protein

Products: NA

Alternate protein names: rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MIENVRSLAFDTIQDILNEGAYSNLRINEVLSENELNAMDKALFTEIVYGTVKRKYTLDFYLKPFVKTKIKAWVRQLLWM
SIYQYVYLDKVPNHAIINEAVEIAKERGGYHNGNVVNGILRTMMRSDLPDFNEIADPKKRMAVEYSMPKWIIDHWATHYG
LEETETILQSFLETTSTTVRANLTRASLDDIIEKLQDEGYDVEKDHDLPYCLHIGGQPIIHSRSFKDGFVSIQDKSSMFV
AHIMNVDRHDHVLDACSAPGGKACHIAEVLMPEGQVGASDIHDHKIDLINFNIKKLRLTNIKAFQHDATKPYDKTYDKIL
VDAPCSGLGVMRHKPEIKYTQSKQHIESLVDLQLEILENVKNNVKIGGEIIYSTCTIEQLENENVIYTFLKNNKNFEFEP
FQHPITGELVKTLQIMPQDFNSDGFFITKIKRKDN

Sequences:

>Translated_435_residues
MIENVRSLAFDTIQDILNEGAYSNLRINEVLSENELNAMDKALFTEIVYGTVKRKYTLDFYLKPFVKTKIKAWVRQLLWM
SIYQYVYLDKVPNHAIINEAVEIAKERGGYHNGNVVNGILRTMMRSDLPDFNEIADPKKRMAVEYSMPKWIIDHWATHYG
LEETETILQSFLETTSTTVRANLTRASLDDIIEKLQDEGYDVEKDHDLPYCLHIGGQPIIHSRSFKDGFVSIQDKSSMFV
AHIMNVDRHDHVLDACSAPGGKACHIAEVLMPEGQVGASDIHDHKIDLINFNIKKLRLTNIKAFQHDATKPYDKTYDKIL
VDAPCSGLGVMRHKPEIKYTQSKQHIESLVDLQLEILENVKNNVKIGGEIIYSTCTIEQLENENVIYTFLKNNKNFEFEP
FQHPITGELVKTLQIMPQDFNSDGFFITKIKRKDN
>Mature_435_residues
MIENVRSLAFDTIQDILNEGAYSNLRINEVLSENELNAMDKALFTEIVYGTVKRKYTLDFYLKPFVKTKIKAWVRQLLWM
SIYQYVYLDKVPNHAIINEAVEIAKERGGYHNGNVVNGILRTMMRSDLPDFNEIADPKKRMAVEYSMPKWIIDHWATHYG
LEETETILQSFLETTSTTVRANLTRASLDDIIEKLQDEGYDVEKDHDLPYCLHIGGQPIIHSRSFKDGFVSIQDKSSMFV
AHIMNVDRHDHVLDACSAPGGKACHIAEVLMPEGQVGASDIHDHKIDLINFNIKKLRLTNIKAFQHDATKPYDKTYDKIL
VDAPCSGLGVMRHKPEIKYTQSKQHIESLVDLQLEILENVKNNVKIGGEIIYSTCTIEQLENENVIYTFLKNNKNFEFEP
FQHPITGELVKTLQIMPQDFNSDGFFITKIKRKDN

Specific function: Unknown

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI76150625, Length=323, Percent_Identity=27.8637770897833, Blast_Score=115, Evalue=9e-26,
Organism=Homo sapiens, GI76150623, Length=323, Percent_Identity=27.8637770897833, Blast_Score=115, Evalue=9e-26,
Organism=Homo sapiens, GI32698918, Length=210, Percent_Identity=32.3809523809524, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI301336155, Length=188, Percent_Identity=31.3829787234043, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI39995082, Length=188, Percent_Identity=31.3829787234043, Blast_Score=93, Evalue=6e-19,
Organism=Homo sapiens, GI270288818, Length=324, Percent_Identity=24.0740740740741, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI8922322, Length=314, Percent_Identity=23.8853503184713, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI23199998, Length=314, Percent_Identity=23.8853503184713, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI270288816, Length=314, Percent_Identity=23.8853503184713, Blast_Score=86, Evalue=6e-17,
Organism=Escherichia coli, GI2367212, Length=444, Percent_Identity=28.6036036036036, Blast_Score=180, Evalue=2e-46,
Organism=Escherichia coli, GI87081985, Length=248, Percent_Identity=27.0161290322581, Blast_Score=105, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17536757, Length=298, Percent_Identity=28.5234899328859, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI25143471, Length=221, Percent_Identity=27.1493212669683, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71998419, Length=225, Percent_Identity=28.4444444444444, Blast_Score=82, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI115534021, Length=225, Percent_Identity=28.4444444444444, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17509941, Length=284, Percent_Identity=29.2253521126761, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6324268, Length=284, Percent_Identity=27.112676056338, Blast_Score=96, Evalue=9e-21,
Organism=Saccharomyces cerevisiae, GI6319447, Length=182, Percent_Identity=31.3186813186813, Blast_Score=85, Evalue=2e-17,
Organism=Drosophila melanogaster, GI22024126, Length=233, Percent_Identity=31.7596566523605, Blast_Score=108, Evalue=9e-24,
Organism=Drosophila melanogaster, GI21355201, Length=185, Percent_Identity=30.2702702702703, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24668781, Length=250, Percent_Identity=25.6, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21356513, Length=250, Percent_Identity=25.6, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21356579, Length=184, Percent_Identity=25.5434782608696, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: NA

Molecular weight: Translated: 50002; Mature: 50002

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS00237 G_PROTEIN_RECEP_F1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIENVRSLAFDTIQDILNEGAYSNLRINEVLSENELNAMDKALFTEIVYGTVKRKYTLDF
CCCCHHHHHHHHHHHHHHCCCCCCEEHHHHHCCCHHHHHHHHHHHHHHHHHHHHEEEEEH
YLKPFVKTKIKAWVRQLLWMSIYQYVYLDKVPNHAIINEAVEIAKERGGYHNGNVVNGIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHH
RTMMRSDLPDFNEIADPKKRMAVEYSMPKWIIDHWATHYGLEETETILQSFLETTSTTVR
HHHHHHCCCCHHHHCCHHHHEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHE
ANLTRASLDDIIEKLQDEGYDVEKDHDLPYCLHIGGQPIIHSRSFKDGFVSIQDKSSMFV
ECCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCEEECCCCCCCEEEEECCCHHHH
AHIMNVDRHDHVLDACSAPGGKACHIAEVLMPEGQVGASDIHDHKIDLINFNIKKLRLTN
HHHHCCCCHHHHHHHHCCCCCCCEEHHHHHCCCCCCCCCCCCCCEEEEEECCEEEEEEEC
IKAFQHDATKPYDKTYDKILVDAPCSGLGVMRHKPEIKYTQSKQHIESLVDLQLEILENV
CHHHHCCCCCCCHHHHHHEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
KNNVKIGGEIIYSTCTIEQLENENVIYTFLKNNKNFEFEPFQHPITGELVKTLQIMPQDF
HCCEEECCEEEEEEEEHHHHCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCC
NSDGFFITKIKRKDN
CCCCEEEEEEECCCC
>Mature Secondary Structure
MIENVRSLAFDTIQDILNEGAYSNLRINEVLSENELNAMDKALFTEIVYGTVKRKYTLDF
CCCCHHHHHHHHHHHHHHCCCCCCEEHHHHHCCCHHHHHHHHHHHHHHHHHHHHEEEEEH
YLKPFVKTKIKAWVRQLLWMSIYQYVYLDKVPNHAIINEAVEIAKERGGYHNGNVVNGIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHH
RTMMRSDLPDFNEIADPKKRMAVEYSMPKWIIDHWATHYGLEETETILQSFLETTSTTVR
HHHHHHCCCCHHHHCCHHHHEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHE
ANLTRASLDDIIEKLQDEGYDVEKDHDLPYCLHIGGQPIIHSRSFKDGFVSIQDKSSMFV
ECCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCEEECCCCCCCEEEEECCCHHHH
AHIMNVDRHDHVLDACSAPGGKACHIAEVLMPEGQVGASDIHDHKIDLINFNIKKLRLTN
HHHHCCCCHHHHHHHHCCCCCCCEEHHHHHCCCCCCCCCCCCCCEEEEEECCEEEEEEEC
IKAFQHDATKPYDKTYDKILVDAPCSGLGVMRHKPEIKYTQSKQHIESLVDLQLEILENV
CHHHHCCCCCCCHHHHHHEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
KNNVKIGGEIIYSTCTIEQLENENVIYTFLKNNKNFEFEPFQHPITGELVKTLQIMPQDF
HCCEEECCEEEEEEEEHHHHCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCC
NSDGFFITKIKRKDN
CCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377; 9086272 [H]