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The map label for this gene is dppE [H]

Identifier: 82750603

GI number: 82750603

Start: 928800

End: 930455

Strand: Direct

Name: dppE [H]

Synonym: SAB0856

Alternate gene names: 82750603

Gene position: 928800-930455 (Clockwise)

Preceding gene: 82750602

Following gene: 82750604

Centisome position: 33.87

GC content: 33.21

Gene sequence:

>1656_bases
ATGACAAGAAAGTTGAAAGCGCTGATTTTAATATTGGTTGCTACAATTGCATTAAGTGGTTGTGCTAATGATGATGGTAT
TTATTCAGATAAAGGTCAAGTATTCAGAAAAATTTTGTCATCAGACTTAACATCCCTTGATACATCATTAATAACGGATG
AAATATCTTCTGAAGTGACTGCGCAAACATTCGAAGGTTTATACACATTAGGAAAAGGTGACAAACCGGTGTTAGGTGTT
GCGAAAGCTTTTCCTGAAAAGAGTAAAGATGGTAAAACTTTAAAGGTTAAATTAAGAAGCGATGCTAAATGGAGCAATGG
TGACAAAGTGACTGCACAAGACTTTGTTTATGCTTGGAGAAAAACAGTTGACCCTAAAACAGGTTCTGAATTTGCATACA
TTATGGGGGACATTAAAAATGCAAGTGATATTAGTACTGGTAAGAAACCTGTAGAGCAATTAGGTATCAAAGCATTAGAT
GATGAAACATTACAAATTGAATTAGAAAAGCCGGTACCATACATTAATCAATTATTAGCACTTAATACATTTGCACCGCA
AAATGAAAAAGTTGCCAAAAAATATGGTAAAAATTATGGCACAGCAGCTGATAGAGCGGTATACAATGGTCCATTTAAAG
TTGATGATTGGAAACAAGAAGATAAAACGTTACTATCTAAAAATCAGTATTATTGGGATAAAAAGAATGTAAAGCTAGAT
AAAGTGAATTATAAAGTTATTAAAGACTTACAAGCCGGTGCTTCATTGTATGATACTGAATCAGTAGATGACGCAATTAT
TACTGCGGATCAAGTGAATAAATATAAAGATAATAAAGGATTAAACTTTGTGTTAACGACTGGGACATTTTTTGTGAAAA
TGAATGAAAAACAATATCCTGATTTTAAAAACAAAAATTTAAGACTGGCTATCGCACAAGCAATAGATAAAAAAGGATAC
GTTGATTCAGTGAAAAACAATGGTTCAATTCCTTCCGATACACTAACAGCTAAAGGCATTGCGAAAGCGCCGAATGGCAA
AGATTATGCGAGTACCATGAATTCACCTCTAAAATATAATCCTAAAGAAGCAAGAGCACACTGGGACAAAGCTAAAAAAG
AGTTAGGTAAAAATGAATTGACATTTTCAATGAACACAGAAGATACACCAGATGCAAAAATATCTGCTGAATATATCAAA
TCGCAAGTTGAGAAAAATTTACCAGGAGTTACTTTGAAAATTAAGCAATTGCCGTTTAAACAAAGAGTATCACTAGAACT
GAGTAACAATTTTGAAGCATCACTTAGTGGTTGGTCTGCAGATTACCCTGATCCTATGGCTTACTTAGAAACAATGACCA
CAGGTAGCGCACAAAATAATACAGACTGGGGTAATAAAGAATACGATCAATTACTTAAAGTAGCAAGAACCAAATTGGCA
CTTCAACCGAACGAACGATATGAAAACTTGAAAAAATCAGAAGAAATGTTCCTAGGAGATGCACCGGTAGCACCAATTTA
TCAAAAAGGTGTTGCACATTTAACAAATCCTCAAGTAAAAGGATTGATTTACCATAAATTTGGTCCAAATAACTCACTTA
AACATGTATATATTGATAAATCGATAGATAAAGAAACAGGTAAGAAGAAAAAATAA

Upstream 100 bases:

>100_bases
AATAAGACCACAGCATTTTGTCTTTAGTACTGAAGAAGAAGCGGCACGACTACGAAAAAATTTGTTGGTGACACAAGATT
AAGAGGAAGGGGGAAATGAA

Downstream 100 bases:

>100_bases
TATGCTTTGTAAATTAGGCTGGAGACATATCTCCAGTCTTTTTGTATTGAAGAAAAACTTTGGGAATAAAAAATGGGGAA
CAATAAAAAAATGTTGAAAA

Product: oligopeptide binding protein

Products: ADP; phosphate; oligopeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 551; Mature: 550

Protein sequence:

>551_residues
MTRKLKALILILVATIALSGCANDDGIYSDKGQVFRKILSSDLTSLDTSLITDEISSEVTAQTFEGLYTLGKGDKPVLGV
AKAFPEKSKDGKTLKVKLRSDAKWSNGDKVTAQDFVYAWRKTVDPKTGSEFAYIMGDIKNASDISTGKKPVEQLGIKALD
DETLQIELEKPVPYINQLLALNTFAPQNEKVAKKYGKNYGTAADRAVYNGPFKVDDWKQEDKTLLSKNQYYWDKKNVKLD
KVNYKVIKDLQAGASLYDTESVDDAIITADQVNKYKDNKGLNFVLTTGTFFVKMNEKQYPDFKNKNLRLAIAQAIDKKGY
VDSVKNNGSIPSDTLTAKGIAKAPNGKDYASTMNSPLKYNPKEARAHWDKAKKELGKNELTFSMNTEDTPDAKISAEYIK
SQVEKNLPGVTLKIKQLPFKQRVSLELSNNFEASLSGWSADYPDPMAYLETMTTGSAQNNTDWGNKEYDQLLKVARTKLA
LQPNERYENLKKSEEMFLGDAPVAPIYQKGVAHLTNPQVKGLIYHKFGPNNSLKHVYIDKSIDKETGKKKK

Sequences:

>Translated_551_residues
MTRKLKALILILVATIALSGCANDDGIYSDKGQVFRKILSSDLTSLDTSLITDEISSEVTAQTFEGLYTLGKGDKPVLGV
AKAFPEKSKDGKTLKVKLRSDAKWSNGDKVTAQDFVYAWRKTVDPKTGSEFAYIMGDIKNASDISTGKKPVEQLGIKALD
DETLQIELEKPVPYINQLLALNTFAPQNEKVAKKYGKNYGTAADRAVYNGPFKVDDWKQEDKTLLSKNQYYWDKKNVKLD
KVNYKVIKDLQAGASLYDTESVDDAIITADQVNKYKDNKGLNFVLTTGTFFVKMNEKQYPDFKNKNLRLAIAQAIDKKGY
VDSVKNNGSIPSDTLTAKGIAKAPNGKDYASTMNSPLKYNPKEARAHWDKAKKELGKNELTFSMNTEDTPDAKISAEYIK
SQVEKNLPGVTLKIKQLPFKQRVSLELSNNFEASLSGWSADYPDPMAYLETMTTGSAQNNTDWGNKEYDQLLKVARTKLA
LQPNERYENLKKSEEMFLGDAPVAPIYQKGVAHLTNPQVKGLIYHKFGPNNSLKHVYIDKSIDKETGKKKK
>Mature_550_residues
TRKLKALILILVATIALSGCANDDGIYSDKGQVFRKILSSDLTSLDTSLITDEISSEVTAQTFEGLYTLGKGDKPVLGVA
KAFPEKSKDGKTLKVKLRSDAKWSNGDKVTAQDFVYAWRKTVDPKTGSEFAYIMGDIKNASDISTGKKPVEQLGIKALDD
ETLQIELEKPVPYINQLLALNTFAPQNEKVAKKYGKNYGTAADRAVYNGPFKVDDWKQEDKTLLSKNQYYWDKKNVKLDK
VNYKVIKDLQAGASLYDTESVDDAIITADQVNKYKDNKGLNFVLTTGTFFVKMNEKQYPDFKNKNLRLAIAQAIDKKGYV
DSVKNNGSIPSDTLTAKGIAKAPNGKDYASTMNSPLKYNPKEARAHWDKAKKELGKNELTFSMNTEDTPDAKISAEYIKS
QVEKNLPGVTLKIKQLPFKQRVSLELSNNFEASLSGWSADYPDPMAYLETMTTGSAQNNTDWGNKEYDQLLKVARTKLAL
QPNERYENLKKSEEMFLGDAPVAPIYQKGVAHLTNPQVKGLIYHKFGPNNSLKHVYIDKSIDKETGKKKK

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the binding of dipeptides with high affinity. Is expressed to facilitate adaptation to nutrient deficiency conditions, which also induce sporulation [H]

COG id: COG4166

COG function: function code E; ABC-type oligopeptide transport system, periplasmic component

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1787495, Length=554, Percent_Identity=27.4368231046931, Blast_Score=184, Evalue=1e-47,
Organism=Escherichia coli, GI87081878, Length=532, Percent_Identity=29.1353383458647, Blast_Score=178, Evalue=7e-46,
Organism=Escherichia coli, GI1789397, Length=503, Percent_Identity=29.2246520874751, Blast_Score=175, Evalue=5e-45,
Organism=Escherichia coli, GI1787052, Length=516, Percent_Identity=23.062015503876, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1787762, Length=506, Percent_Identity=22.7272727272727, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1789966, Length=502, Percent_Identity=21.7131474103586, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1789887, Length=295, Percent_Identity=23.3898305084746, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: 760 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2360 Molecules/Cell In: Stationary-Phase,

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 61511; Mature: 61380

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRKLKALILILVATIALSGCANDDGIYSDKGQVFRKILSSDLTSLDTSLITDEISSEVT
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQTFEGLYTLGKGDKPVLGVAKAFPEKSKDGKTLKVKLRSDAKWSNGDKVTAQDFVYAWR
HHHHHHHHCCCCCCCCEEHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHH
KTVDPKTGSEFAYIMGDIKNASDISTGKKPVEQLGIKALDDETLQIELEKPVPYINQLLA
HHCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHCCEEECCCEEEEEECCCCHHHHHHHH
LNTFAPQNEKVAKKYGKNYGTAADRAVYNGPFKVDDWKQEDKTLLSKNQYYWDKKNVKLD
HHCCCCCCHHHHHHHCCCCCCHHHHHEECCCCCCCCCCHHHHHHHHCCCEEECCCCEEEE
KVNYKVIKDLQAGASLYDTESVDDAIITADQVNKYKDNKGLNFVLTTGTFFVKMNEKQYP
CCHHHHHHHHHHCCCCCCCCCCCCCEEEHHHHHHHCCCCCCEEEEECCEEEEEECCCCCC
DFKNKNLRLAIAQAIDKKGYVDSVKNNGSIPSDTLTAKGIAKAPNGKDYASTMNSPLKYN
CCCCCCEEEEHHHHHCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCC
PKEARAHWDKAKKELGKNELTFSMNTEDTPDAKISAEYIKSQVEKNLPGVTLKIKQLPFK
CHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCC
QRVSLELSNNFEASLSGWSADYPDPMAYLETMTTGSAQNNTDWGNKEYDQLLKVARTKLA
CEEEEEECCCCEEEECCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHC
LQPNERYENLKKSEEMFLGDAPVAPIYQKGVAHLTNPQVKGLIYHKFGPNNSLKHVYIDK
CCCCHHHHHHHHHHHHEECCCCCCHHHHHCHHHCCCCCCCEEEEEEECCCCCCEEEEECC
SIDKETGKKKK
CCCCCCCCCCC
>Mature Secondary Structure 
TRKLKALILILVATIALSGCANDDGIYSDKGQVFRKILSSDLTSLDTSLITDEISSEVT
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQTFEGLYTLGKGDKPVLGVAKAFPEKSKDGKTLKVKLRSDAKWSNGDKVTAQDFVYAWR
HHHHHHHHCCCCCCCCEEHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHH
KTVDPKTGSEFAYIMGDIKNASDISTGKKPVEQLGIKALDDETLQIELEKPVPYINQLLA
HHCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHCCEEECCCEEEEEECCCCHHHHHHHH
LNTFAPQNEKVAKKYGKNYGTAADRAVYNGPFKVDDWKQEDKTLLSKNQYYWDKKNVKLD
HHCCCCCCHHHHHHHCCCCCCHHHHHEECCCCCCCCCCHHHHHHHHCCCEEECCCCEEEE
KVNYKVIKDLQAGASLYDTESVDDAIITADQVNKYKDNKGLNFVLTTGTFFVKMNEKQYP
CCHHHHHHHHHHCCCCCCCCCCCCCEEEHHHHHHHCCCCCCEEEEECCEEEEEECCCCCC
DFKNKNLRLAIAQAIDKKGYVDSVKNNGSIPSDTLTAKGIAKAPNGKDYASTMNSPLKYN
CCCCCCEEEEHHHHHCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCC
PKEARAHWDKAKKELGKNELTFSMNTEDTPDAKISAEYIKSQVEKNLPGVTLKIKQLPFK
CHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCC
QRVSLELSNNFEASLSGWSADYPDPMAYLETMTTGSAQNNTDWGNKEYDQLLKVARTKLA
CEEEEEECCCCEEEECCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHC
LQPNERYENLKKSEEMFLGDAPVAPIYQKGVAHLTNPQVKGLIYHKFGPNNSLKHVYIDK
CCCCHHHHHHHHHHHHEECCCCCCHHHHHCHHHCCCCCCCEEEEEEECCCCCCEEEEECC
SIDKETGKKKK
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; oligopeptides [Periplasm]; H2O [C]

Specific reaction: ATP + oligopeptides [Periplasm] + H2O = ADP + phosphate + oligopeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1766370; 9384377 [H]