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The map label for this gene is csdB

Identifier: 82750526

GI number: 82750526

Start: 844822

End: 846063

Strand: Direct

Name: csdB

Synonym: SAB0776

Alternate gene names: 82750526

Gene position: 844822-846063 (Clockwise)

Preceding gene: 82750525

Following gene: 82750527

Centisome position: 30.8

GC content: 37.12

Gene sequence:

>1242_bases
GTGGCCGAACACTCATTTGACGTTAATGAAGTAATCAAGGATTTTCCGATATTAGATCAAAAAGTCAATGGCAAACGTTT
AGCATATCTTGATTCAACAGCGACAAGTCAAACGCCTGTGCAAGTGTTAAATGTTTTAGAGGATTACTACAAGCGTTATA
ATTCAAACGTTCATCGTGGTGTTCATACATTAGGATCATTGGCAACTGATGGTTATGAAAATGCTCGTGAAACCGTTCGT
CGTTTTATTAATGCGAAGTATTTTGAAGAAATCATTTTCACACGCGGAACAACTGCATCGATTAACCTTGTAGCACATAG
CTATGGTGATGCAAATGTTGAAGAGGGCGATGAAATTGTTGTCACTGAAATGGAACATCATGCCAATATTGTTCCTTGGC
AACAGTTAGCAAAGCGTAAAAATGCGACATTGAAATTTATACCAATGACAGCTGACGGGGAATTAAACATCGAAGATATT
AAGCAAACGATTAATGATAAAACAAAGATCGTTGCTATTGCACATATTTCTAATGTACTCGGTACAATTAATGATGTTAA
AACCATTGCAGAAATAGCTCATCAACATGGTGCAATTATCAGTGTTGATGGGGCGCAAGCAGCACCACATATGAAACTTG
ATATGCAAGAAATGAATGCTGATTTTTATAGTTTTAGTGGACATAAAATGCTTGGACCAACAGGTATTGGCGTATTATTT
GGTAAACGTGAGTTACTACAAAAAATGGAACCGATTGAGTTCGGTGGCGACATGATTGATTTTGTAAGTAAGTATGATGC
AACATGGGCTGATTTACCTACTAAATTTGAGGCGGGTACTCCATTAATTGCTCAAGCAATTGGGCTTGCAGAAGCTATTC
GATATTTAGAACGCATAGGTTTTGAGGCAATTCATAAATATGAACAAGAATTAACGATATATGCTTATGAGCAAATGTCT
GCAATTGAAGGAATTGAAATTTATGGCCCGCCAAAGGATCGTCGTGCAGGTGTAATAACGTTTAATTTACAAGATGTACA
TCCACACGATGTTGCTACAGCCGTAGATACAGAAGGTGTAGCGGTTAGAGCTGGGCATCATTGTGCGCAACCGTTAATGA
AATGGTTAAATGTGTCTTCAACAGCTAGAGCGAGTTTTTATATATACAACACGAAAGAAGACATTGATCAGTTAATAAAT
GCCTTGAAACAAACGAAGGAGTTTTTCTCTTATGAATTTTAA

Upstream 100 bases:

>100_bases
AAGTTTGTAATAGATATAGACTGTCGATATTGGTATAAGACTAATACAACGTCAGTATTTAAATGATTAGGATTTTTATT
TAAGAAAGGTCGTGAATGAA

Downstream 100 bases:

>100_bases
TAATCTAGATCAATTATATAGATCTGTCATTATGGATCATTATAAAAATCCTAGAAATAAAGGTGTATTAGATAACGGGT
CTATGACAGTAGATATGAAT

Product: cysteine desulfurase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 413; Mature: 412

Protein sequence:

>413_residues
MAEHSFDVNEVIKDFPILDQKVNGKRLAYLDSTATSQTPVQVLNVLEDYYKRYNSNVHRGVHTLGSLATDGYENARETVR
RFINAKYFEEIIFTRGTTASINLVAHSYGDANVEEGDEIVVTEMEHHANIVPWQQLAKRKNATLKFIPMTADGELNIEDI
KQTINDKTKIVAIAHISNVLGTINDVKTIAEIAHQHGAIISVDGAQAAPHMKLDMQEMNADFYSFSGHKMLGPTGIGVLF
GKRELLQKMEPIEFGGDMIDFVSKYDATWADLPTKFEAGTPLIAQAIGLAEAIRYLERIGFEAIHKYEQELTIYAYEQMS
AIEGIEIYGPPKDRRAGVITFNLQDVHPHDVATAVDTEGVAVRAGHHCAQPLMKWLNVSSTARASFYIYNTKEDIDQLIN
ALKQTKEFFSYEF

Sequences:

>Translated_413_residues
MAEHSFDVNEVIKDFPILDQKVNGKRLAYLDSTATSQTPVQVLNVLEDYYKRYNSNVHRGVHTLGSLATDGYENARETVR
RFINAKYFEEIIFTRGTTASINLVAHSYGDANVEEGDEIVVTEMEHHANIVPWQQLAKRKNATLKFIPMTADGELNIEDI
KQTINDKTKIVAIAHISNVLGTINDVKTIAEIAHQHGAIISVDGAQAAPHMKLDMQEMNADFYSFSGHKMLGPTGIGVLF
GKRELLQKMEPIEFGGDMIDFVSKYDATWADLPTKFEAGTPLIAQAIGLAEAIRYLERIGFEAIHKYEQELTIYAYEQMS
AIEGIEIYGPPKDRRAGVITFNLQDVHPHDVATAVDTEGVAVRAGHHCAQPLMKWLNVSSTARASFYIYNTKEDIDQLIN
ALKQTKEFFSYEF
>Mature_412_residues
AEHSFDVNEVIKDFPILDQKVNGKRLAYLDSTATSQTPVQVLNVLEDYYKRYNSNVHRGVHTLGSLATDGYENARETVRR
FINAKYFEEIIFTRGTTASINLVAHSYGDANVEEGDEIVVTEMEHHANIVPWQQLAKRKNATLKFIPMTADGELNIEDIK
QTINDKTKIVAIAHISNVLGTINDVKTIAEIAHQHGAIISVDGAQAAPHMKLDMQEMNADFYSFSGHKMLGPTGIGVLFG
KRELLQKMEPIEFGGDMIDFVSKYDATWADLPTKFEAGTPLIAQAIGLAEAIRYLERIGFEAIHKYEQELTIYAYEQMSA
IEGIEIYGPPKDRRAGVITFNLQDVHPHDVATAVDTEGVAVRAGHHCAQPLMKWLNVSSTARASFYIYNTKEDIDQLINA
LKQTKEFFSYEF

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=344, Percent_Identity=24.7093023255814, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI156713448, Length=262, Percent_Identity=25.9541984732824, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI1787970, Length=405, Percent_Identity=47.9012345679012, Blast_Score=409, Evalue=1e-115,
Organism=Escherichia coli, GI1789175, Length=381, Percent_Identity=39.1076115485564, Blast_Score=290, Evalue=9e-80,
Organism=Escherichia coli, GI48994898, Length=390, Percent_Identity=23.0769230769231, Blast_Score=107, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI193211090, Length=432, Percent_Identity=24.537037037037, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI25143064, Length=228, Percent_Identity=29.3859649122807, Blast_Score=110, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6319831, Length=400, Percent_Identity=25.25, Blast_Score=125, Evalue=1e-29,
Organism=Drosophila melanogaster, GI20129463, Length=246, Percent_Identity=31.3008130081301, Blast_Score=123, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 46305; Mature: 46174

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEHSFDVNEVIKDFPILDQKVNGKRLAYLDSTATSQTPVQVLNVLEDYYKRYNSNVHRG
CCCCCCCHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCHHHH
VHTLGSLATDGYENARETVRRFINAKYFEEIIFTRGTTASINLVAHSYGDANVEEGDEIV
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCEEE
VTEMEHHANIVPWQQLAKRKNATLKFIPMTADGELNIEDIKQTINDKTKIVAIAHISNVL
EEEHHHCCCCCCHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHCCCCEEEEHHHHHHHH
GTINDVKTIAEIAHQHGAIISVDGAQAAPHMKLDMQEMNADFYSFSGHKMLGPTGIGVLF
HHHHHHHHHHHHHHHCCCEEEECCCCCCCCCEEEHHHHCCCCEECCCCEEECCCCCHHHC
GKRELLQKMEPIEFGGDMIDFVSKYDATWADLPTKFEAGTPLIAQAIGLAEAIRYLERIG
CHHHHHHHCCCCCCCCHHHHHHHHCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHC
FEAIHKYEQELTIYAYEQMSAIEGIEIYGPPKDRRAGVITFNLQDVHPHDVATAVDTEGV
HHHHHHHHHHHEEEEHHHHHHHCCEEEECCCCCCCCEEEEEEECCCCCCHHHHHCCCCCE
AVRAGHHCAQPLMKWLNVSSTARASFYIYNTKEDIDQLINALKQTKEFFSYEF
EEECCHHHHHHHHHHHCCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AEHSFDVNEVIKDFPILDQKVNGKRLAYLDSTATSQTPVQVLNVLEDYYKRYNSNVHRG
CCCCCCHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCHHHH
VHTLGSLATDGYENARETVRRFINAKYFEEIIFTRGTTASINLVAHSYGDANVEEGDEIV
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCEEE
VTEMEHHANIVPWQQLAKRKNATLKFIPMTADGELNIEDIKQTINDKTKIVAIAHISNVL
EEEHHHCCCCCCHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHCCCCEEEEHHHHHHHH
GTINDVKTIAEIAHQHGAIISVDGAQAAPHMKLDMQEMNADFYSFSGHKMLGPTGIGVLF
HHHHHHHHHHHHHHHCCCEEEECCCCCCCCCEEEHHHHCCCCEECCCCEEECCCCCHHHC
GKRELLQKMEPIEFGGDMIDFVSKYDATWADLPTKFEAGTPLIAQAIGLAEAIRYLERIG
CHHHHHHHCCCCCCCCHHHHHHHHCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHC
FEAIHKYEQELTIYAYEQMSAIEGIEIYGPPKDRRAGVITFNLQDVHPHDVATAVDTEGV
HHHHHHHHHHHEEEEHHHHHHHCCEEEECCCCCCCCEEEEEEECCCCCCHHHHHCCCCCE
AVRAGHHCAQPLMKWLNVSSTARASFYIYNTKEDIDQLINALKQTKEFFSYEF
EEECCHHHHHHHHHHHCCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA