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The map label for this gene is xpt

Identifier: 82750099

GI number: 82750099

Start: 383830

End: 384408

Strand: Direct

Name: xpt

Synonym: SAB0338

Alternate gene names: 82750099

Gene position: 383830-384408 (Clockwise)

Preceding gene: 82750093

Following gene: 82750100

Centisome position: 14.0

GC content: 35.58

Gene sequence:

>579_bases
GTGGAGTTACTAGGACAAAAAGTAAAGGAAGACGGCGTTGTCATTGATGAGAAGATTTTAAAAGTTGATGGATTTTTAAA
TCATCAAATTGATGCAAAGTTAATGAATGAAGTTGGTCGCACTTTTTACGAGCAATTTAAAGATAAAGGGATTACTAAAA
TCTTAACCATTGAAGCTTCCGGTATCGCACCAGCAATCATGGCTGCACTGCATTTTGATGTGCCATGTTTATTTGCGAAA
AAAGCAAAACCTAGCACTTTGACGGATGGTTATTATGAAACATCTATTCATTCATTTACTAAAAATAAAACAAGTACGGT
CATTGTTTCGAAAGAATTTTTATCAGAAGAAGATACTGTACTCATCATCGATGACTTTTTAGCAAATGGTGATGCTTCAT
TAGGGTTATACGATATCACACAGCAAGCGAATGCTAAGACAGCTGGTATTGGTATTGTTGTTGAAAAGAGTTTTCAAAAT
GGGCATCAACGCTTAGAAGAAGCAGGTTTAACAGTTTCTTCTCTCTGCAAGGTTGCTTCACTAGAAGGAAATAAAGTGAC
ATTGGTGGGAGAAGAATAA

Upstream 100 bases:

>100_bases
CTCATAAACCCTGAAACTATTATTTAGTTTGGGGATTTTTTTGTATCTAGCACCAATTAAAGAGCAAAATGTTTCACACA
AATCTGAGGAGGTTTTAAGA

Downstream 100 bases:

>100_bases
TGAAAAATTTAATCCTAAGTGCTCAACATCTTTTAGCTATGTACGCAGGTGCCATCTTAGTTCCAATCATTGTTGGTACA
AGTTTGAAGTTTACATCTGA

Product: xanthine phosphoribosyltransferase

Products: NA

Alternate protein names: XPRTase [H]

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MELLGQKVKEDGVVIDEKILKVDGFLNHQIDAKLMNEVGRTFYEQFKDKGITKILTIEASGIAPAIMAALHFDVPCLFAK
KAKPSTLTDGYYETSIHSFTKNKTSTVIVSKEFLSEEDTVLIIDDFLANGDASLGLYDITQQANAKTAGIGIVVEKSFQN
GHQRLEEAGLTVSSLCKVASLEGNKVTLVGEE

Sequences:

>Translated_192_residues
MELLGQKVKEDGVVIDEKILKVDGFLNHQIDAKLMNEVGRTFYEQFKDKGITKILTIEASGIAPAIMAALHFDVPCLFAK
KAKPSTLTDGYYETSIHSFTKNKTSTVIVSKEFLSEEDTVLIIDDFLANGDASLGLYDITQQANAKTAGIGIVVEKSFQN
GHQRLEEAGLTVSSLCKVASLEGNKVTLVGEE
>Mature_192_residues
MELLGQKVKEDGVVIDEKILKVDGFLNHQIDAKLMNEVGRTFYEQFKDKGITKILTIEASGIAPAIMAALHFDVPCLFAK
KAKPSTLTDGYYETSIHSFTKNKTSTVIVSKEFLSEEDTVLIIDDFLANGDASLGLYDITQQANAKTAGIGIVVEKSFQN
GHQRLEEAGLTVSSLCKVASLEGNKVTLVGEE

Specific function: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis [H]

COG id: COG0503

COG function: function code F; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XPT subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836
- InterPro:   IPR010079 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.22 [H]

Molecular weight: Translated: 20914; Mature: 20914

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELLGQKVKEDGVVIDEKILKVDGFLNHQIDAKLMNEVGRTFYEQFKDKGITKILTIEAS
CCCHHHHHHCCCEEEHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECC
GIAPAIMAALHFDVPCLFAKKAKPSTLTDGYYETSIHSFTKNKTSTVIVSKEFLSEEDTV
CCHHHHHHHHHCCCCEEEECCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEHHHCCCCCCE
LIIDDFLANGDASLGLYDITQQANAKTAGIGIVVEKSFQNGHQRLEEAGLTVSSLCKVAS
EEEECCCCCCCCCCEEEEHHHCCCCCCCCEEEEEECCHHHHHHHHHHHCCCHHHHHHHHC
LEGNKVTLVGEE
CCCCEEEEEECC
>Mature Secondary Structure
MELLGQKVKEDGVVIDEKILKVDGFLNHQIDAKLMNEVGRTFYEQFKDKGITKILTIEAS
CCCHHHHHHCCCEEEHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECC
GIAPAIMAALHFDVPCLFAKKAKPSTLTDGYYETSIHSFTKNKTSTVIVSKEFLSEEDTV
CCHHHHHHHHHCCCCEEEECCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEHHHCCCCCCE
LIIDDFLANGDASLGLYDITQQANAKTAGIGIVVEKSFQNGHQRLEEAGLTVSSLCKVAS
EEEECCCCCCCCCCEEEEHHHCCCCCCCCEEEEEECCHHHHHHHHHHHCCCHHHHHHHHC
LEGNKVTLVGEE
CCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA