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The map label for this gene is 82749938

Identifier: 82749938

GI number: 82749938

Start: 209129

End: 211012

Strand: Direct

Name: 82749938

Synonym: SAB0169

Alternate gene names: NA

Gene position: 209129-211012 (Clockwise)

Preceding gene: 82749936

Following gene: 82749943

Centisome position: 7.63

GC content: 35.4

Gene sequence:

>1884_bases
ATGAAAAAGCAAATAATTTCGCTAGGCGCATTAGCAGTTGCATCTAGCTTATTTACATGGGATAACAAAGCAGATGCGAT
AGTAACAAAGGATTATAGCGGGAAATCACAAGTTAATGCTGGGAGTAAAAATGGGACACCGATTTCTAATGGTTACTTTT
GGGGGAAAATCGATAGTCTAGAATCACAATTTTCTAAAGCATTAGCAATAATTGAAGAGTATCAATATGGTGAGAAAGAA
TATAAAGATGCAAAAGATAAGTTTATGGATAGAATTTTGTCAGAAGATCAATATCTTTTGGAGAAAAAGAAAGCTCTGTA
TGAGAAATATAAAGAGTGGTATAAAAAGCACAAAGAGATAAACCCAACTTATCCAAAAATGCAAACATTCCATGAATTTA
GTGTATATAATCTAACTATGGAAGAATACAATGAGATTTCTAAATCTTTGAAAGATGCGGAAGAAGAGTTTCGTAAAAAT
GTAAGCGAAGTTCAAGAGAAAGAAGTCAAATTAAAAACATATAGCGAAGATGAAGAAGAAAAGGCAACTAAAGAAGTATA
CGATCTTGTAGCCGAAGTTGATACTATATATGTATCTTATTTTGGACATGATAAACATGGTCAAAGTGCTAAAGAATTGC
GTGCGAAATTAGATTTAATAATTGGAGAGGAAAAAAACGCCTTTCGTATTACTAATGAACGTATAAAAAATGAAATGATT
TATGACTTGAATTCTATTATTGACGATTTCTTTATGGAAACTAACCAAAATAGACCGGAAAATATAACAAAATTTGATTG
GGATAAGCATGATTATAGAAATAAACTAGAAAACAAAGCACATTTTGAGGCTCTAGTTGAAGAAACGAAAAAAGCAGTTA
AAGAAGCAGATGCATCTTGGAAAAAGAAAACTGTCAAAAATTACGATGAATCTGTAACAAAAGCACATGTTGTAAAAGAA
GAGAAGAAAGTTGAAGAACCTCAATCACCTAAAGTTGATAACCAACAAGATGACAAAGCAACACAACCAGTGGCACAGCC
ATTAGTAAAAATTCCACAAGGGACAATCTATGGTGAAACTGTAAAAGGTCCGGAATATCCAACGATGGAAAATAAAACGT
TACAAGGTGAAATCGTTCAAGGTCCTGATTTCCCAACAATGGAACAAAACAGACCATCATTAAGCGATAATTATACTCAA
CCATCGTTAACGAACCCTATTTTAGAAGGTCTTGAAGGTAGCTCATCTAAACTTGAAATAAAACCACAAGGTACTGAATC
AACGTTGAAAGGTATTCAAGGAGAATCAAGTGATATTGAAGTTAAACCTCAAGCAACTGAAACAACAGAAGCTTCTCAAT
ATGGTCCGAGACCGCAATTTAACAAAACACCTAAGTATGTGAAATATAGAGATGCTGGTACAGGTATCCGTGAATACAAC
GATGGAACATTTGGATATGAAGCGAGACCAAGATTCAATAAGCCATCAGAAACAAATGCATACAACGTAACGACAAATCA
AGATGGCACAGTATCATATGGCGCTCGCCCGACACAAAACAAGCCAAGCAAAACAAACGCATATAACGTAACAACACATG
CAAACGGCCAAGTATCATACGGTGCTCGCCCGACACAAAACAAGCCAAGCAAAACAAACGAGTATAACGTAACAACACAT
GCAAATGGCCAAGTATCATATGGTGCTCGTCCGACATACAAGAAGCCAAGTGAAACGAACGCATATAACGTAACAACACA
TGCAAACGGTCAAGTATCATACGGCGCTCGCCCTACACAAAACAAGCCAAGTAAAACAAATGCATACAATGTAACAACAC
ATGCAGATGGTACTGCGACATATGGCTCTAGAGTAACAAAATAA

Upstream 100 bases:

>100_bases
AATGCTTTGTTTATTCTAGTTAATATATAGTTAATGTCTTTTAATATTTTGTTTCTTTAATGTAGATTGGGCAATTACAT
TTTGGAGGAATTAAAAAATT

Downstream 100 bases:

>100_bases
GTTTATAACTCTATCCATAGACATACAGTCAATACAAAACATTACGTATCTTTACAACAGTAATCATGCATTCTATGATG
CTTCTAACTGAATTAAAGCA

Product: staphylocoagulase precursor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 627; Mature: 627

Protein sequence:

>627_residues
MKKQIISLGALAVASSLFTWDNKADAIVTKDYSGKSQVNAGSKNGTPISNGYFWGKIDSLESQFSKALAIIEEYQYGEKE
YKDAKDKFMDRILSEDQYLLEKKKALYEKYKEWYKKHKEINPTYPKMQTFHEFSVYNLTMEEYNEISKSLKDAEEEFRKN
VSEVQEKEVKLKTYSEDEEEKATKEVYDLVAEVDTIYVSYFGHDKHGQSAKELRAKLDLIIGEEKNAFRITNERIKNEMI
YDLNSIIDDFFMETNQNRPENITKFDWDKHDYRNKLENKAHFEALVEETKKAVKEADASWKKKTVKNYDESVTKAHVVKE
EKKVEEPQSPKVDNQQDDKATQPVAQPLVKIPQGTIYGETVKGPEYPTMENKTLQGEIVQGPDFPTMEQNRPSLSDNYTQ
PSLTNPILEGLEGSSSKLEIKPQGTESTLKGIQGESSDIEVKPQATETTEASQYGPRPQFNKTPKYVKYRDAGTGIREYN
DGTFGYEARPRFNKPSETNAYNVTTNQDGTVSYGARPTQNKPSKTNAYNVTTHANGQVSYGARPTQNKPSKTNEYNVTTH
ANGQVSYGARPTYKKPSETNAYNVTTHANGQVSYGARPTQNKPSKTNAYNVTTHADGTATYGSRVTK

Sequences:

>Translated_627_residues
MKKQIISLGALAVASSLFTWDNKADAIVTKDYSGKSQVNAGSKNGTPISNGYFWGKIDSLESQFSKALAIIEEYQYGEKE
YKDAKDKFMDRILSEDQYLLEKKKALYEKYKEWYKKHKEINPTYPKMQTFHEFSVYNLTMEEYNEISKSLKDAEEEFRKN
VSEVQEKEVKLKTYSEDEEEKATKEVYDLVAEVDTIYVSYFGHDKHGQSAKELRAKLDLIIGEEKNAFRITNERIKNEMI
YDLNSIIDDFFMETNQNRPENITKFDWDKHDYRNKLENKAHFEALVEETKKAVKEADASWKKKTVKNYDESVTKAHVVKE
EKKVEEPQSPKVDNQQDDKATQPVAQPLVKIPQGTIYGETVKGPEYPTMENKTLQGEIVQGPDFPTMEQNRPSLSDNYTQ
PSLTNPILEGLEGSSSKLEIKPQGTESTLKGIQGESSDIEVKPQATETTEASQYGPRPQFNKTPKYVKYRDAGTGIREYN
DGTFGYEARPRFNKPSETNAYNVTTNQDGTVSYGARPTQNKPSKTNAYNVTTHANGQVSYGARPTQNKPSKTNEYNVTTH
ANGQVSYGARPTYKKPSETNAYNVTTHANGQVSYGARPTQNKPSKTNAYNVTTHADGTATYGSRVTK
>Mature_627_residues
MKKQIISLGALAVASSLFTWDNKADAIVTKDYSGKSQVNAGSKNGTPISNGYFWGKIDSLESQFSKALAIIEEYQYGEKE
YKDAKDKFMDRILSEDQYLLEKKKALYEKYKEWYKKHKEINPTYPKMQTFHEFSVYNLTMEEYNEISKSLKDAEEEFRKN
VSEVQEKEVKLKTYSEDEEEKATKEVYDLVAEVDTIYVSYFGHDKHGQSAKELRAKLDLIIGEEKNAFRITNERIKNEMI
YDLNSIIDDFFMETNQNRPENITKFDWDKHDYRNKLENKAHFEALVEETKKAVKEADASWKKKTVKNYDESVTKAHVVKE
EKKVEEPQSPKVDNQQDDKATQPVAQPLVKIPQGTIYGETVKGPEYPTMENKTLQGEIVQGPDFPTMEQNRPSLSDNYTQ
PSLTNPILEGLEGSSSKLEIKPQGTESTLKGIQGESSDIEVKPQATETTEASQYGPRPQFNKTPKYVKYRDAGTGIREYN
DGTFGYEARPRFNKPSETNAYNVTTNQDGTVSYGARPTQNKPSKTNAYNVTTHANGQVSYGARPTQNKPSKTNEYNVTTH
ANGQVSYGARPTYKKPSETNAYNVTTHANGQVSYGARPTQNKPSKTNAYNVTTHADGTATYGSRVTK

Specific function: Staphylocoagulase is an extracellular protein which specifically forms a complex with human prothrombin. This complex named staphylothrombin can clot fibrinogen without any proteolytic cleavage of prothrombin [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the staphylocoagulase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014874
- InterPro:   IPR001443 [H]

Pfam domain/function: PF08764 Coagulase; PF04022 Staphylcoagulse [H]

EC number: NA

Molecular weight: Translated: 71178; Mature: 71178

Theoretical pI: Translated: 6.77; Mature: 6.77

Prosite motif: PS00429 STAPHYLOCOAGULASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKQIISLGALAVASSLFTWDNKADAIVTKDYSGKSQVNAGSKNGTPISNGYFWGKIDSL
CCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEHHHH
ESQFSKALAIIEEYQYGEKEYKDAKDKFMDRILSEDQYLLEKKKALYEKYKEWYKKHKEI
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCC
NPTYPKMQTFHEFSVYNLTMEEYNEISKSLKDAEEEFRKNVSEVQEKEVKLKTYSEDEEE
CCCCCHHHHHHHHHEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHH
KATKEVYDLVAEVDTIYVSYFGHDKHGQSAKELRAKLDLIIGEEKNAFRITNERIKNEMI
HHHHHHHHHHHHHHHEEEEEECCCCCCCHHHHHHHHHHEEECCCCCCEEEHHHHHHHHHH
YDLNSIIDDFFMETNQNRPENITKFDWDKHDYRNKLENKAHFEALVEETKKAVKEADASW
HHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KKKTVKNYDESVTKAHVVKEEKKVEEPQSPKVDNQQDDKATQPVAQPLVKIPQGTIYGET
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEECCC
VKGPEYPTMENKTLQGEIVQGPDFPTMEQNRPSLSDNYTQPSLTNPILEGLEGSSSKLEI
CCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCEEEE
KPQGTESTLKGIQGESSDIEVKPQATETTEASQYGPRPQFNKTPKYVKYRDAGTGIREYN
ECCCCHHHHHCCCCCCCCEEECCCCCCCCCHHHCCCCCCCCCCCCEEEEECCCCCCCCCC
DGTFGYEARPRFNKPSETNAYNVTTNQDGTVSYGARPTQNKPSKTNAYNVTTHANGQVSY
CCCCCCCCCCCCCCCCCCCCEEEECCCCCCEECCCCCCCCCCCCCCCEEEEECCCCEEEC
GARPTQNKPSKTNEYNVTTHANGQVSYGARPTYKKPSETNAYNVTTHANGQVSYGARPTQ
CCCCCCCCCCCCCCEEEEECCCCEEECCCCCCCCCCCCCCCEEEEECCCCEEECCCCCCC
NKPSKTNAYNVTTHADGTATYGSRVTK
CCCCCCCCEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure
MKKQIISLGALAVASSLFTWDNKADAIVTKDYSGKSQVNAGSKNGTPISNGYFWGKIDSL
CCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEHHHH
ESQFSKALAIIEEYQYGEKEYKDAKDKFMDRILSEDQYLLEKKKALYEKYKEWYKKHKEI
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCC
NPTYPKMQTFHEFSVYNLTMEEYNEISKSLKDAEEEFRKNVSEVQEKEVKLKTYSEDEEE
CCCCCHHHHHHHHHEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHH
KATKEVYDLVAEVDTIYVSYFGHDKHGQSAKELRAKLDLIIGEEKNAFRITNERIKNEMI
HHHHHHHHHHHHHHHEEEEEECCCCCCCHHHHHHHHHHEEECCCCCCEEEHHHHHHHHHH
YDLNSIIDDFFMETNQNRPENITKFDWDKHDYRNKLENKAHFEALVEETKKAVKEADASW
HHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KKKTVKNYDESVTKAHVVKEEKKVEEPQSPKVDNQQDDKATQPVAQPLVKIPQGTIYGET
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEECCC
VKGPEYPTMENKTLQGEIVQGPDFPTMEQNRPSLSDNYTQPSLTNPILEGLEGSSSKLEI
CCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCEEEE
KPQGTESTLKGIQGESSDIEVKPQATETTEASQYGPRPQFNKTPKYVKYRDAGTGIREYN
ECCCCHHHHHCCCCCCCCEEECCCCCCCCCHHHCCCCCCCCCCCCEEEEECCCCCCCCCC
DGTFGYEARPRFNKPSETNAYNVTTNQDGTVSYGARPTQNKPSKTNAYNVTTHANGQVSY
CCCCCCCCCCCCCCCCCCCCEEEECCCCCCEECCCCCCCCCCCCCCCEEEEECCCCEEEC
GARPTQNKPSKTNEYNVTTHANGQVSYGARPTYKKPSETNAYNVTTHANGQVSYGARPTQ
CCCCCCCCCCCCCCEEEEECCCCEEECCCCCCCCCCCCCCCEEEEECCCCEEECCCCCCC
NKPSKTNAYNVTTHADGTATYGSRVTK
CCCCCCCCEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2587230; 3941089 [H]