Click here to switch to the map view.

The map label for this gene is hemX [H]

Identifier: 82703801

GI number: 82703801

Start: 3088267

End: 3089316

Strand: Reverse

Name: hemX [H]

Synonym: Nmul_A2688

Alternate gene names: 82703801

Gene position: 3089316-3088267 (Counterclockwise)

Preceding gene: 82703802

Following gene: 82703800

Centisome position: 97.02

GC content: 56.95

Gene sequence:

>1050_bases
ATGGGCATGGAAACTCAGTCTGCTGATATTGATCAACCGCAGAAAGCAGGGGCGAGATGGCTTGCGCACGCCAATCCCCT
GCTGGTTTTTGCTTTGATTCTGATCCTGGTTTTCGCCTGGCAATGGTACGACACGCGCAGTGAAATCGCAGGGCTGCGGC
ATGAGCTGGCAAGACGACTGGCCGAGGCGGATACTTCGGGCAAGGAGGCGCGCAATGCCGCAGCCGATGCCGTCGAGGCG
GGACGCCGTGCGGAAACGAAGCTCGACCTTCTTGAAGATAAACTGGCTGAATCGCAGAGTCAGCAGGTTGCCCTGGAAGC
GCTTTACCAGGAACTTACGCGAAGCCGCGATGAAGCAATGCTGGAAGAAGTGGAGCAGCTACTGCTTATCGCCAACCAGC
AACTGCAACTAGCAAGCAACGTCAAATCCGCCCTGATTGCAATGCAGGAGGCGGATAGCCGGCTCCTGCGCACGGATCGT
CCGCAACTGGCTTCTTTGCGGAAAACCATTGCAAAGGATATGGGTCTGCTGAAATCGGTGCCGTATGTTGACACCACGGA
AATCAGTTTGCGCCTGGATAATCTTGCCGCCTCCGTCGATACGCTGCCGCTGGCAATGGAGTTTCGACCGCCTGAGAGCG
CCTCTTCCCCGCCTCCCGTTCCCATCTCCGAAAATGTATGGCTGCGCTTTCTGCGTCAAGTATGGGAGGATTTCAAACGG
CTGGTGCGGATACAGTATATGGACAGCCCGGATGTCGCCCTGCTGTCGCCCTCGCAAGCGTATTTCCTGCGCGAGAATTT
GAAGTTGCGGCTCTTATCCGCGCGCTATGCGTTGCTTGCGCACAACGGCCCCAGCTTCAAGGCTGACCTCGACGCGTCCA
GGGAGCAGATCGGGCGTTATTACAACACTCAAGCCCAACCTGTCATCGATTTCCGGGAAGCATTGCAGCAATTGGGCGAG
ACTGATATCGGGGCTGAGTTGCCGCGTATCTCCGCAAGTCTCGATGCGGTTCGTAACTACAGGTTGACGCGTGACCGGGG
AAACAGGTGA

Upstream 100 bases:

>100_bases
GCGGGTTTGCAGGATTATTTTTCCGGCCACATGGGTTGAAAGGTGACGGCAAAGGTAACAGCGGCGAAGGGCGCCAACAC
AATTTTGCTCCTACGCAATC

Downstream 100 bases:

>100_bases
AGGGGGCGCTCTGGCTTCTGGCCCTGTTCATGATTGCCGTGGCGGTTACCATCGCCGCCACTTATAACAGCGGCTACGTG
CTGATTGTCGCCCAGCCCTA

Product: hypothetical protein

Products: NA

Alternate protein names: Urogen-III methylase; ORF X [H]

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MGMETQSADIDQPQKAGARWLAHANPLLVFALILILVFAWQWYDTRSEIAGLRHELARRLAEADTSGKEARNAAADAVEA
GRRAETKLDLLEDKLAESQSQQVALEALYQELTRSRDEAMLEEVEQLLLIANQQLQLASNVKSALIAMQEADSRLLRTDR
PQLASLRKTIAKDMGLLKSVPYVDTTEISLRLDNLAASVDTLPLAMEFRPPESASSPPPVPISENVWLRFLRQVWEDFKR
LVRIQYMDSPDVALLSPSQAYFLRENLKLRLLSARYALLAHNGPSFKADLDASREQIGRYYNTQAQPVIDFREALQQLGE
TDIGAELPRISASLDAVRNYRLTRDRGNR

Sequences:

>Translated_349_residues
MGMETQSADIDQPQKAGARWLAHANPLLVFALILILVFAWQWYDTRSEIAGLRHELARRLAEADTSGKEARNAAADAVEA
GRRAETKLDLLEDKLAESQSQQVALEALYQELTRSRDEAMLEEVEQLLLIANQQLQLASNVKSALIAMQEADSRLLRTDR
PQLASLRKTIAKDMGLLKSVPYVDTTEISLRLDNLAASVDTLPLAMEFRPPESASSPPPVPISENVWLRFLRQVWEDFKR
LVRIQYMDSPDVALLSPSQAYFLRENLKLRLLSARYALLAHNGPSFKADLDASREQIGRYYNTQAQPVIDFREALQQLGE
TDIGAELPRISASLDAVRNYRLTRDRGNR
>Mature_348_residues
GMETQSADIDQPQKAGARWLAHANPLLVFALILILVFAWQWYDTRSEIAGLRHELARRLAEADTSGKEARNAAADAVEAG
RRAETKLDLLEDKLAESQSQQVALEALYQELTRSRDEAMLEEVEQLLLIANQQLQLASNVKSALIAMQEADSRLLRTDRP
QLASLRKTIAKDMGLLKSVPYVDTTEISLRLDNLAASVDTLPLAMEFRPPESASSPPPVPISENVWLRFLRQVWEDFKRL
VRIQYMDSPDVALLSPSQAYFLRENLKLRLLSARYALLAHNGPSFKADLDASREQIGRYYNTQAQPVIDFREALQQLGET
DIGAELPRISASLDAVRNYRLTRDRGNR

Specific function: Siroheme and cobalamin biosynthesis. [C]

COG id: COG2959

COG function: function code H; Uncharacterized enzyme of heme biosynthesis

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790235, Length=213, Percent_Identity=29.5774647887324, Blast_Score=85, Evalue=7e-18,

Paralogues:

None

Copy number: 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007470 [H]

Pfam domain/function: PF04375 HemX [H]

EC number: =2.1.1.107 [H]

Molecular weight: Translated: 39337; Mature: 39206

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGMETQSADIDQPQKAGARWLAHANPLLVFALILILVFAWQWYDTRSEIAGLRHELARRL
CCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
AEADTSGKEARNAAADAVEAGRRAETKLDLLEDKLAESQSQQVALEALYQELTRSRDEAM
HHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
LEEVEQLLLIANQQLQLASNVKSALIAMQEADSRLLRTDRPQLASLRKTIAKDMGLLKSV
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCC
PYVDTTEISLRLDNLAASVDTLPLAMEFRPPESASSPPPVPISENVWLRFLRQVWEDFKR
CCCCCCHHEEEHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
LVRIQYMDSPDVALLSPSQAYFLRENLKLRLLSARYALLAHNGPSFKADLDASREQIGRY
HHHHHCCCCCCEEEECCCHHHHHHHCCCEEHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
YNTQAQPVIDFREALQQLGETDIGAELPRISASLDAVRNYRLTRDRGNR
HCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
GMETQSADIDQPQKAGARWLAHANPLLVFALILILVFAWQWYDTRSEIAGLRHELARRL
CCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
AEADTSGKEARNAAADAVEAGRRAETKLDLLEDKLAESQSQQVALEALYQELTRSRDEAM
HHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
LEEVEQLLLIANQQLQLASNVKSALIAMQEADSRLLRTDRPQLASLRKTIAKDMGLLKSV
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCC
PYVDTTEISLRLDNLAASVDTLPLAMEFRPPESASSPPPVPISENVWLRFLRQVWEDFKR
CCCCCCHHEEEHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
LVRIQYMDSPDVALLSPSQAYFLRENLKLRLLSARYALLAHNGPSFKADLDASREQIGRY
HHHHHCCCCCCEEEECCCHHHHHHHCCCEEHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
YNTQAQPVIDFREALQQLGETDIGAELPRISASLDAVRNYRLTRDRGNR
HCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3062586; 3054815; 1379743; 9278503; 9298646 [H]