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The map label for this gene is trpD

Identifier: 82703678

GI number: 82703678

Start: 2935801

End: 2936853

Strand: Reverse

Name: trpD

Synonym: Nmul_A2563

Alternate gene names: 82703678

Gene position: 2936853-2935801 (Counterclockwise)

Preceding gene: 82703679

Following gene: 82703677

Centisome position: 92.23

GC content: 57.08

Gene sequence:

>1053_bases
GTGAGTCCGCAGGAAGCATTGACGCGCCTCATCGAGCACCGTGAAATCTTTCATGATGAAATGCTGTCGCTCATGCGACA
GATCATGCGCGGAGAACTCTCCCCCACGCTGATTTCAGCGATTATTACCGGGTTGCGTGTAAAGAAGGAAACCGTGGGCG
AGATCGCTGCTGCGGCACAGGTAATGCGCGAATTTGCCGCCCCCGTGCAAGTGGAGGATGACCGCCTCGTCGATACATGT
GGAACAGGAGGGGATAGTGCCCATACTTTCAACATTTCCACCACCGCTGCGTTCGTCGCTGCGGCTGCCGGCGCACGCGT
GGCGAAACATGGCGGACGCTCTGTTTCCAGCAAATCGGGAAGTGCCGATGTGCTCGAAGCACTGGGTGTCAATCTCGACC
AGACACCCGCGCAAATAGCGGAGAACATAAGGGAAATCGGGCTCGGTTTCATGTTCGCGCCCAATTTCCACAGCGCCATG
AAACATGCCGCCTCGGTACGGCGGGAACTGGGGGTGCGCACCCTGTTTAATATCCTCGGGCCGCTGACCAATCCCGCCGG
AGCAAAAAATCAACTGCTGGGCGTGTTCCATCCCGATCTCGTGGGCATCGTCACACGCGTTTTGCATCGCCTGGGCAGCC
GTCATGTCATGGTGGTTCATGGCTGCACCGGCAACCAAGGCGGACTGGATGAGATTACGATTGCTGGCGAGACGCTGGTG
GGTGAACTCAGGCACGGCCAGATCCTCGAATATACCATCAGGCCGGAAGATTTCGGCATGAAAGCGGCTCGCATTGAAAC
CATACAAGCGCATGACACCGCTCAGTCTGCGGAGATGCTGAGAGCGATATTGAATAATCAGCCGGGGCCGCCGCGGGATA
TCGTATTGCTGAATGCGGGCGCCACGATTTATGTGGCAGGTATCGCAGAGTCGCTCGCGCAAGGTGTAAAAAAAGCGCAT
GCCGCCATAGAAAGCGGCGCCGCGAGGAAAAAATTGCAGGAGCTGGTGGAATTCTCGAACCGGCAGAACCGCGGTGAGGT
TTCTCTTGTTTGA

Upstream 100 bases:

>100_bases
CGGGAATTTTCTGAACAGTGAAAACTGAGGGAAGTGGCATGAATCCCAGCCAAAGGGTTGAAAGGATTGATGGGGCGGCA
TCATTCAGTAGCAGGCCACT

Downstream 100 bases:

>100_bases
TCATGGCTAATATTCTTCAGGAGATTGTGGCGACAAAGCGACAGGAGATTGCGGCATTGAAAGCGCAGGGTTCTCTCGCC
GTGCTTCGCCGCCAGGCGGA

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 349

Protein sequence:

>350_residues
MSPQEALTRLIEHREIFHDEMLSLMRQIMRGELSPTLISAIITGLRVKKETVGEIAAAAQVMREFAAPVQVEDDRLVDTC
GTGGDSAHTFNISTTAAFVAAAAGARVAKHGGRSVSSKSGSADVLEALGVNLDQTPAQIAENIREIGLGFMFAPNFHSAM
KHAASVRRELGVRTLFNILGPLTNPAGAKNQLLGVFHPDLVGIVTRVLHRLGSRHVMVVHGCTGNQGGLDEITIAGETLV
GELRHGQILEYTIRPEDFGMKAARIETIQAHDTAQSAEMLRAILNNQPGPPRDIVLLNAGATIYVAGIAESLAQGVKKAH
AAIESGAARKKLQELVEFSNRQNRGEVSLV

Sequences:

>Translated_350_residues
MSPQEALTRLIEHREIFHDEMLSLMRQIMRGELSPTLISAIITGLRVKKETVGEIAAAAQVMREFAAPVQVEDDRLVDTC
GTGGDSAHTFNISTTAAFVAAAAGARVAKHGGRSVSSKSGSADVLEALGVNLDQTPAQIAENIREIGLGFMFAPNFHSAM
KHAASVRRELGVRTLFNILGPLTNPAGAKNQLLGVFHPDLVGIVTRVLHRLGSRHVMVVHGCTGNQGGLDEITIAGETLV
GELRHGQILEYTIRPEDFGMKAARIETIQAHDTAQSAEMLRAILNNQPGPPRDIVLLNAGATIYVAGIAESLAQGVKKAH
AAIESGAARKKLQELVEFSNRQNRGEVSLV
>Mature_349_residues
SPQEALTRLIEHREIFHDEMLSLMRQIMRGELSPTLISAIITGLRVKKETVGEIAAAAQVMREFAAPVQVEDDRLVDTCG
TGGDSAHTFNISTTAAFVAAAAGARVAKHGGRSVSSKSGSADVLEALGVNLDQTPAQIAENIREIGLGFMFAPNFHSAMK
HAASVRRELGVRTLFNILGPLTNPAGAKNQLLGVFHPDLVGIVTRVLHRLGSRHVMVVHGCTGNQGGLDEITIAGETLVG
ELRHGQILEYTIRPEDFGMKAARIETIQAHDTAQSAEMLRAILNNQPGPPRDIVLLNAGATIYVAGIAESLAQGVKKAHA
AIESGAARKKLQELVEFSNRQNRGEVSLV

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=284, Percent_Identity=40.1408450704225, Blast_Score=201, Evalue=6e-53,
Organism=Saccharomyces cerevisiae, GI6320561, Length=362, Percent_Identity=27.9005524861878, Blast_Score=129, Evalue=6e-31,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_NITMU (Q2Y5W9)

Other databases:

- EMBL:   CP000103
- RefSeq:   YP_413244.1
- HSSP:   P66992
- ProteinModelPortal:   Q2Y5W9
- SMR:   Q2Y5W9
- STRING:   Q2Y5W9
- GeneID:   3784643
- GenomeReviews:   CP000103_GR
- KEGG:   nmu:Nmul_A2563
- eggNOG:   COG0547
- HOGENOM:   HBG559996
- OMA:   LGVYSPE
- PhylomeDB:   Q2Y5W9
- BioCyc:   NMUL323848:NMUL_A2563-MONOMER
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 37416; Mature: 37285

Theoretical pI: Translated: 7.21; Mature: 7.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPQEALTRLIEHREIFHDEMLSLMRQIMRGELSPTLISAIITGLRVKKETVGEIAAAAQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VMREFAAPVQVEDDRLVDTCGTGGDSAHTFNISTTAAFVAAAAGARVAKHGGRSVSSKSG
HHHHHCCCCEECCCCHHHHCCCCCCCCEEEECHHHHHHHHHHHHHHHHHCCCCCCCCCCC
SADVLEALGVNLDQTPAQIAENIREIGLGFMFAPNFHSAMKHAASVRRELGVRTLFNILG
CHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHC
PLTNPAGAKNQLLGVFHPDLVGIVTRVLHRLGSRHVMVVHGCTGNQGGLDEITIAGETLV
CCCCCCCCCCCEEECCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEECCHHHH
GELRHGQILEYTIRPEDFGMKAARIETIQAHDTAQSAEMLRAILNNQPGPPRDIVLLNAG
HHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECC
ATIYVAGIAESLAQGVKKAHAAIESGAARKKLQELVEFSNRQNRGEVSLV
CEEEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCEECC
>Mature Secondary Structure 
SPQEALTRLIEHREIFHDEMLSLMRQIMRGELSPTLISAIITGLRVKKETVGEIAAAAQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VMREFAAPVQVEDDRLVDTCGTGGDSAHTFNISTTAAFVAAAAGARVAKHGGRSVSSKSG
HHHHHCCCCEECCCCHHHHCCCCCCCCEEEECHHHHHHHHHHHHHHHHHCCCCCCCCCCC
SADVLEALGVNLDQTPAQIAENIREIGLGFMFAPNFHSAMKHAASVRRELGVRTLFNILG
CHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHC
PLTNPAGAKNQLLGVFHPDLVGIVTRVLHRLGSRHVMVVHGCTGNQGGLDEITIAGETLV
CCCCCCCCCCCEEECCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEECCHHHH
GELRHGQILEYTIRPEDFGMKAARIETIQAHDTAQSAEMLRAILNNQPGPPRDIVLLNAG
HHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECC
ATIYVAGIAESLAQGVKKAHAAIESGAARKKLQELVEFSNRQNRGEVSLV
CEEEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA