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The map label for this gene is mraY [H]

Identifier: 82703612

GI number: 82703612

Start: 2852901

End: 2853995

Strand: Reverse

Name: mraY [H]

Synonym: Nmul_A2497

Alternate gene names: 82703612

Gene position: 2853995-2852901 (Counterclockwise)

Preceding gene: 82703613

Following gene: 82703611

Centisome position: 89.63

GC content: 55.16

Gene sequence:

>1095_bases
ATGGCTGCCATGCTGCTAGAGCTTGCTCAATGGTTTGCCGGAGACATCCGCCTGCTCAACGTGTTCAGTTACATTACATT
GCGTACGGTTCTGGCTGCGCTCACCGCGCTGATAATCTCGTTTATCGTGGGTCCGGCGATGATACGGAAGCTCACCGCCT
ACAAAATCGGCCAGGCGGTTCGCGACGACGGACCCCAGACACATCTGGTCAAGGCGGGCACACCCACCATGGGTGGAGCG
CTGATACTCGTCTCTATCGCCATTACCACCTTGCTCTGGGCGGATCTCAGCAATCGCTACGTGTGGATTGTCCTGATCAC
AACCCTCGGTTTCGGCATGATCGGTTGGGTGGATGATTACCGCAAGGTGGTATATCGCAATCCGAAAGGACTTTCCGCCC
GGGCGAAACTTTTCTGGCAATCGGCCATTGCGATCCTGGTGGCGCTCTACCTGGTGCTGACGGCCGAACTGCCCGCGCAG
ACAACCCTGATAGTTCCCTTCTTCAAACAGGTGGCCGTCCCGCTTGGCGTGACAGGATTCGTGGCGCTCACCTATTTCGT
CATCGTCGGTACCAGCAATGCGGTAAACCTGACCGACGGGTTGGATGGTCTCGCTATCATGCCTACCGTGATGATCAGCA
GCGCTCTGGCGATTTTTTCCTATGTGGCCGGCCATGCGGTATTCGCAAAATATCTCGGTATGCCTCATATCCCCCAGGCC
GGTGAACTCGCGGTTTTCTGCGGTGCTCTGGCGGGGGCGGGACTTGCTTTCCTGTGGTTTAACGCTTATCCGGCGGAAGT
CTTCATGGGAGATGTCGGAGCGCTTGCCTTGGGTGCGGCACTTGGAATCGTGACAGTGATAGTGCGACAGGAAATCGTTA
TGCTCATCATGGGAGGCGTGTTTGTAGTGGAAACCCTGTCGGTCATGCTGCAGGTGGCTTCATTCAAGCTGATCGGCAAG
CGCATTTTTCGTATGGCGCCGTTACATCATCATTACGAATTGAAAGGCTGGAAGGAAAACCAGGTAGTGGTCCGGTTCTG
GATCATTACCATGATGCTAGTGCTGTTCGGTTTGTCTTCCCTGAAGCTGAGATAA

Upstream 100 bases:

>100_bases
CGTCTGGAAGCCGGGTTATGAGTTTACAGGCCGCGAATCCAGTTATCGACGTCATAGTCCTCTTCGGTGAGTCTGGTAAA
TCCCGGGGCATTTCACACGG

Downstream 100 bases:

>100_bases
AGTTGAAATCATGAACCTGCAAGGCAGAACTGTTCTGGTACTGGGCCTCGGAGAGACCGGCCTTTCCATGGCAAAATGGT
TGTTTCGGCGCGGAGCGCTG

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase [H]

Number of amino acids: Translated: 364; Mature: 363

Protein sequence:

>364_residues
MAAMLLELAQWFAGDIRLLNVFSYITLRTVLAALTALIISFIVGPAMIRKLTAYKIGQAVRDDGPQTHLVKAGTPTMGGA
LILVSIAITTLLWADLSNRYVWIVLITTLGFGMIGWVDDYRKVVYRNPKGLSARAKLFWQSAIAILVALYLVLTAELPAQ
TTLIVPFFKQVAVPLGVTGFVALTYFVIVGTSNAVNLTDGLDGLAIMPTVMISSALAIFSYVAGHAVFAKYLGMPHIPQA
GELAVFCGALAGAGLAFLWFNAYPAEVFMGDVGALALGAALGIVTVIVRQEIVMLIMGGVFVVETLSVMLQVASFKLIGK
RIFRMAPLHHHYELKGWKENQVVVRFWIITMMLVLFGLSSLKLR

Sequences:

>Translated_364_residues
MAAMLLELAQWFAGDIRLLNVFSYITLRTVLAALTALIISFIVGPAMIRKLTAYKIGQAVRDDGPQTHLVKAGTPTMGGA
LILVSIAITTLLWADLSNRYVWIVLITTLGFGMIGWVDDYRKVVYRNPKGLSARAKLFWQSAIAILVALYLVLTAELPAQ
TTLIVPFFKQVAVPLGVTGFVALTYFVIVGTSNAVNLTDGLDGLAIMPTVMISSALAIFSYVAGHAVFAKYLGMPHIPQA
GELAVFCGALAGAGLAFLWFNAYPAEVFMGDVGALALGAALGIVTVIVRQEIVMLIMGGVFVVETLSVMLQVASFKLIGK
RIFRMAPLHHHYELKGWKENQVVVRFWIITMMLVLFGLSSLKLR
>Mature_363_residues
AAMLLELAQWFAGDIRLLNVFSYITLRTVLAALTALIISFIVGPAMIRKLTAYKIGQAVRDDGPQTHLVKAGTPTMGGAL
ILVSIAITTLLWADLSNRYVWIVLITTLGFGMIGWVDDYRKVVYRNPKGLSARAKLFWQSAIAILVALYLVLTAELPAQT
TLIVPFFKQVAVPLGVTGFVALTYFVIVGTSNAVNLTDGLDGLAIMPTVMISSALAIFSYVAGHAVFAKYLGMPHIPQAG
ELAVFCGALAGAGLAFLWFNAYPAEVFMGDVGALALGAALGIVTVIVRQEIVMLIMGGVFVVETLSVMLQVASFKLIGKR
IFRMAPLHHHYELKGWKENQVVVRFWIITMMLVLFGLSSLKLR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan [H]

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786275, Length=361, Percent_Identity=59.2797783933518, Blast_Score=412, Evalue=1e-116,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4 [H]

EC number: =2.7.8.13 [H]

Molecular weight: Translated: 39509; Mature: 39378

Theoretical pI: Translated: 10.04; Mature: 10.04

Prosite motif: PS01347 MRAY_1 ; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAMLLELAQWFAGDIRLLNVFSYITLRTVLAALTALIISFIVGPAMIRKLTAYKIGQAV
CHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RDDGPQTHLVKAGTPTMGGALILVSIAITTLLWADLSNRYVWIVLITTLGFGMIGWVDDY
HCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHCCHHHHHHHHH
RKVVYRNPKGLSARAKLFWQSAIAILVALYLVLTAELPAQTTLIVPFFKQVAVPLGVTGF
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHCCCHHHH
VALTYFVIVGTSNAVNLTDGLDGLAIMPTVMISSALAIFSYVAGHAVFAKYLGMPHIPQA
HHHHHHHHCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GELAVFCGALAGAGLAFLWFNAYPAEVFMGDVGALALGAALGIVTVIVRQEIVMLIMGGV
CCHHHHHHHHHHCCHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVVETLSVMLQVASFKLIGKRIFRMAPLHHHYELKGWKENQVVVRFWIITMMLVLFGLSS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCHHH
LKLR
HCCC
>Mature Secondary Structure 
AAMLLELAQWFAGDIRLLNVFSYITLRTVLAALTALIISFIVGPAMIRKLTAYKIGQAV
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RDDGPQTHLVKAGTPTMGGALILVSIAITTLLWADLSNRYVWIVLITTLGFGMIGWVDDY
HCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHCCHHHHHHHHH
RKVVYRNPKGLSARAKLFWQSAIAILVALYLVLTAELPAQTTLIVPFFKQVAVPLGVTGF
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHCCCHHHH
VALTYFVIVGTSNAVNLTDGLDGLAIMPTVMISSALAIFSYVAGHAVFAKYLGMPHIPQA
HHHHHHHHCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GELAVFCGALAGAGLAFLWFNAYPAEVFMGDVGALALGAALGIVTVIVRQEIVMLIMGGV
CCHHHHHHHHHHCCHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVVETLSVMLQVASFKLIGKRIFRMAPLHHHYELKGWKENQVVVRFWIITMMLVLFGLSS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCHHH
LKLR
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA