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The map label for this gene is ftsW [H]

Identifier: 82703610

GI number: 82703610

Start: 2850304

End: 2851464

Strand: Reverse

Name: ftsW [H]

Synonym: Nmul_A2495

Alternate gene names: 82703610

Gene position: 2851464-2850304 (Counterclockwise)

Preceding gene: 82703611

Following gene: 82703609

Centisome position: 89.55

GC content: 55.9

Gene sequence:

>1161_bases
ATGATTTATCAGTACGGTACCGGAAAGCAGAAAGTTCTGCCTGCGGATTTCGACCAGGCCCTGATCTGGACAGCAATACT
CCTGCTGAGCCTTGGGCTGGTGATGGTTTATTCCGCCTCGATTTCGATTGCCGAGGGCGAGGGCAGCGGTTACCCGACCT
ATTTTCTCATCCGGCACGCCGCCTATGTCGCGGCAGGTTTGCTGGTGGCCGTTGTTGCGTTCCAGGTCCCCATGGAGTCG
TGGCAGAAATATTCCTTCCAACTGTTTCTGCTGGGGGGATGCCTGCTGGCCCTGGTGCTGGTTCCCGGCGTGGGCCGCGA
AATCAATGGTAGCCGCCGCTGGATATCCTTGCTGGTGGTGAATCTTCAACCGTCGGAATTCATGAAATTGTTCATGGTCA
TCTACGTGGCCAATTACACGGTGCGCAAATCCGCCTTTCTGGGAAGTTTCCGCAAGGGTTTTCTTCCCATGCTGATCATC
ACGCTCATCGTAGGGGCTCTCCTGCTGCTCGAGCCGGATTTTGGCGCCTTCGTTGTCATTACCACTGTCATGATGGCCAT
ATTGTTTCTGGGAGGAATGGACCTGAAACTATTCGCCGGGCTGATTGGTTTCCTGATTGCTGGCCTTCTTGCCCTGGTCT
GGAACGCCCCTTATCGCATGCAGCGTTTCTTCGGGTTTCTGGATCCATGGGATGACCCCTACGGAAAAGGATACCAGTTG
AGCCATGCGCTGATTGCATTCGGACGGGGTGAATGGCTGGGTGTGGGCCTGGGCGGAAGTGTTGAAAAGCTTTTCTATCT
GCCGGAGGCGCATACCGACTTTCTTCTGGCTGTGATTGCAGAGGAACTCGGTTTCGTCGGTGTCCTGATCGTGCTGGCGT
TGTTTGCCTGGATAATAGCGCGCGCATTCATCATTGGCCGCCAGTCGGCAGTCAGGGGACGTTATTTTCCCGCACTCGTG
GCGCAGGGTATCGGTGTATGGCTGGGAGTGCAGACATTCATCAACGTGGGCGTGAATATGGGAGTCCTCCCGCCGAAGGG
ACTCACGCTGCCGTTGATGAGTTTCGGTGGCAGCAGCATCGTTGCAAGCTGTCTCTCGCTGGCGGTGCTGCTGCGCGCGG
ATTGGGAAAACCGGCAGTTGGCGAGAGGTTATCGGATATGA

Upstream 100 bases:

>100_bases
TATGTGCATCGGGCGGAGGCGTTCGTTGCGGCGGTAAGAAGCATGCAGGCCGCACGTGCAGGCGGTAATTCAGCTGGGGT
TGCAGGACGACATTGATCAG

Downstream 100 bases:

>100_bases
AAAATTCAGGAATGGCGTCTTGAGCCATACGATTCTCATTATGGCGGGGGGAACCGGCGGGCATGTATTTCCCGGTCTTG
CCGTGGCGGAGTATTTGAAG

Product: cell cycle protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MIYQYGTGKQKVLPADFDQALIWTAILLLSLGLVMVYSASISIAEGEGSGYPTYFLIRHAAYVAAGLLVAVVAFQVPMES
WQKYSFQLFLLGGCLLALVLVPGVGREINGSRRWISLLVVNLQPSEFMKLFMVIYVANYTVRKSAFLGSFRKGFLPMLII
TLIVGALLLLEPDFGAFVVITTVMMAILFLGGMDLKLFAGLIGFLIAGLLALVWNAPYRMQRFFGFLDPWDDPYGKGYQL
SHALIAFGRGEWLGVGLGGSVEKLFYLPEAHTDFLLAVIAEELGFVGVLIVLALFAWIIARAFIIGRQSAVRGRYFPALV
AQGIGVWLGVQTFINVGVNMGVLPPKGLTLPLMSFGGSSIVASCLSLAVLLRADWENRQLARGYRI

Sequences:

>Translated_386_residues
MIYQYGTGKQKVLPADFDQALIWTAILLLSLGLVMVYSASISIAEGEGSGYPTYFLIRHAAYVAAGLLVAVVAFQVPMES
WQKYSFQLFLLGGCLLALVLVPGVGREINGSRRWISLLVVNLQPSEFMKLFMVIYVANYTVRKSAFLGSFRKGFLPMLII
TLIVGALLLLEPDFGAFVVITTVMMAILFLGGMDLKLFAGLIGFLIAGLLALVWNAPYRMQRFFGFLDPWDDPYGKGYQL
SHALIAFGRGEWLGVGLGGSVEKLFYLPEAHTDFLLAVIAEELGFVGVLIVLALFAWIIARAFIIGRQSAVRGRYFPALV
AQGIGVWLGVQTFINVGVNMGVLPPKGLTLPLMSFGGSSIVASCLSLAVLLRADWENRQLARGYRI
>Mature_386_residues
MIYQYGTGKQKVLPADFDQALIWTAILLLSLGLVMVYSASISIAEGEGSGYPTYFLIRHAAYVAAGLLVAVVAFQVPMES
WQKYSFQLFLLGGCLLALVLVPGVGREINGSRRWISLLVVNLQPSEFMKLFMVIYVANYTVRKSAFLGSFRKGFLPMLII
TLIVGALLLLEPDFGAFVVITTVMMAILFLGGMDLKLFAGLIGFLIAGLLALVWNAPYRMQRFFGFLDPWDDPYGKGYQL
SHALIAFGRGEWLGVGLGGSVEKLFYLPEAHTDFLLAVIAEELGFVGVLIVLALFAWIIARAFIIGRQSAVRGRYFPALV
AQGIGVWLGVQTFINVGVNMGVLPPKGLTLPLMSFGGSSIVASCLSLAVLLRADWENRQLARGYRI

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=362, Percent_Identity=42.5414364640884, Blast_Score=283, Evalue=1e-77,
Organism=Escherichia coli, GI1786853, Length=343, Percent_Identity=33.2361516034985, Blast_Score=139, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 42227; Mature: 42227

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYQYGTGKQKVLPADFDQALIWTAILLLSLGLVMVYSASISIAEGEGSGYPTYFLIRHA
CEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCHHHHHHHH
AYVAAGLLVAVVAFQVPMESWQKYSFQLFLLGGCLLALVLVPGVGREINGSRRWISLLVV
HHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEE
NLQPSEFMKLFMVIYVANYTVRKSAFLGSFRKGFLPMLIITLIVGALLLLEPDFGAFVVI
ECCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
TTVMMAILFLGGMDLKLFAGLIGFLIAGLLALVWNAPYRMQRFFGFLDPWDDPYGKGYQL
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCEEH
SHALIAFGRGEWLGVGLGGSVEKLFYLPEAHTDFLLAVIAEELGFVGVLIVLALFAWIIA
HHHHHEECCCCEEEECCCCCHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAFIIGRQSAVRGRYFPALVAQGIGVWLGVQTFINVGVNMGVLPPKGLTLPLMSFGGSSI
HHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEHHHHCCCHHH
VASCLSLAVLLRADWENRQLARGYRI
HHHHHHHHHHHHCCCCCCHHHCCCCC
>Mature Secondary Structure
MIYQYGTGKQKVLPADFDQALIWTAILLLSLGLVMVYSASISIAEGEGSGYPTYFLIRHA
CEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCHHHHHHHH
AYVAAGLLVAVVAFQVPMESWQKYSFQLFLLGGCLLALVLVPGVGREINGSRRWISLLVV
HHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEE
NLQPSEFMKLFMVIYVANYTVRKSAFLGSFRKGFLPMLIITLIVGALLLLEPDFGAFVVI
ECCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
TTVMMAILFLGGMDLKLFAGLIGFLIAGLLALVWNAPYRMQRFFGFLDPWDDPYGKGYQL
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCEEH
SHALIAFGRGEWLGVGLGGSVEKLFYLPEAHTDFLLAVIAEELGFVGVLIVLALFAWIIA
HHHHHEECCCCEEEECCCCCHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAFIIGRQSAVRGRYFPALVAQGIGVWLGVQTFINVGVNMGVLPPKGLTLPLMSFGGSSI
HHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEHHHHCCCHHH
VASCLSLAVLLRADWENRQLARGYRI
HHHHHHHHHHHHCCCCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]