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The map label for this gene is murG

Identifier: 82703609

GI number: 82703609

Start: 2849211

End: 2850284

Strand: Reverse

Name: murG

Synonym: Nmul_A2494

Alternate gene names: 82703609

Gene position: 2850284-2849211 (Counterclockwise)

Preceding gene: 82703610

Following gene: 82703608

Centisome position: 89.51

GC content: 58.57

Gene sequence:

>1074_bases
TTGAGCCATACGATTCTCATTATGGCGGGGGGAACCGGCGGGCATGTATTTCCCGGTCTTGCCGTGGCGGAGTATTTGAA
GGCGGCCGGGTGGCGTATAGTCTGGCTTGGAACAGAAGGGGGAATGGAAACAACGCTGGCGCGGCAGCAGGGGCATGCCC
TGGAGACGATTCGTTTCTCCGGATTGCGGGGGAAAAACGTTCGCACCTGGTTGTTGCTGCCCGCGCGTCTGTTGCTGGCA
TTCTGGCAAAGTGCAAGAGTAATACGGAAGGTTCGGCCGGACGTGGTGTTGGGTATGGGCGGGTATCCCGCCTTTCCGGG
GGGAATGATGGCCTCGCTGCTTGCGCGGCCGTTGCTGATACACGAACAAAACTCCATTCCGGGACTTGCCAACAGAATCC
TCTCGAGACTCGCCGACAGGGTATTGCTGGGATTTCCCGACGCGATCAAAAGTGAAAAAAAAGCGGTGTTTTGCGGTAAT
CCCGTACGTGACGAAATCACCAGGCTCGCGCCGCCTGCACAGAGGTATGCGGGTCGCAGCGGAAGCATCAAGCTGCTGGT
GGTAGGGGGAAGTCTGGGCGCTCAGGCCCTGAATACCATCGTACCCCGGGCATTGAAGCGGATACCTGAAGGAATGCGCC
CGCAGGTGACGCATCAGGCGGGGGCCCGGCATCTGGAGGCGCTGAAGCAGAATTATTCCGAAGCGGGAGTGGAGGGTGAA
CTGGTTACGTTTATCGACAATATGGCATCCCGCTATGGAGAGAGTGATCTCGTGATCTGCCGCGCGGGCGCACTTACCGT
CTCGGAGTTGGCCGCAGCGGGTGTAGCCAGCATTCTGGTGCCTTTTCCCTATGCCGTGGACGATCATCAGAGCACGAACG
CAAAATTTTTGAGCGGGAAAGGGGCTGCGATATTGCTACCCCAGAGCCAACTGACTCCGGAAGGACTGGCAGAGCTGCTG
GTGGGTATGAGCAGGGGCCAACTTATGGAAATGGCATGCCGGGCGAGAGAACTGGCGCAACCCGACGCTACCCGGTGCGT
GGCCGAGACGTGCATGCAAATGGTTGCAGTTTAA

Upstream 100 bases:

>100_bases
GTTGCAAGCTGTCTCTCGCTGGCGGTGCTGCTGCGCGCGGATTGGGAAAACCGGCAGTTGGCGAGAGGTTATCGGATATG
AAAAATTCAGGAATGGCGTC

Downstream 100 bases:

>100_bases
GGTGGTCATGTTGCCTTTGTCTTACAGCAACTGCACGTACTTTATGTGTAAACAATGAAAGTATGAAACACAAAGTTAAG
CATATTCATTTTGTGGGCAT

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 357; Mature: 356

Protein sequence:

>357_residues
MSHTILIMAGGTGGHVFPGLAVAEYLKAAGWRIVWLGTEGGMETTLARQQGHALETIRFSGLRGKNVRTWLLLPARLLLA
FWQSARVIRKVRPDVVLGMGGYPAFPGGMMASLLARPLLIHEQNSIPGLANRILSRLADRVLLGFPDAIKSEKKAVFCGN
PVRDEITRLAPPAQRYAGRSGSIKLLVVGGSLGAQALNTIVPRALKRIPEGMRPQVTHQAGARHLEALKQNYSEAGVEGE
LVTFIDNMASRYGESDLVICRAGALTVSELAAAGVASILVPFPYAVDDHQSTNAKFLSGKGAAILLPQSQLTPEGLAELL
VGMSRGQLMEMACRARELAQPDATRCVAETCMQMVAV

Sequences:

>Translated_357_residues
MSHTILIMAGGTGGHVFPGLAVAEYLKAAGWRIVWLGTEGGMETTLARQQGHALETIRFSGLRGKNVRTWLLLPARLLLA
FWQSARVIRKVRPDVVLGMGGYPAFPGGMMASLLARPLLIHEQNSIPGLANRILSRLADRVLLGFPDAIKSEKKAVFCGN
PVRDEITRLAPPAQRYAGRSGSIKLLVVGGSLGAQALNTIVPRALKRIPEGMRPQVTHQAGARHLEALKQNYSEAGVEGE
LVTFIDNMASRYGESDLVICRAGALTVSELAAAGVASILVPFPYAVDDHQSTNAKFLSGKGAAILLPQSQLTPEGLAELL
VGMSRGQLMEMACRARELAQPDATRCVAETCMQMVAV
>Mature_356_residues
SHTILIMAGGTGGHVFPGLAVAEYLKAAGWRIVWLGTEGGMETTLARQQGHALETIRFSGLRGKNVRTWLLLPARLLLAF
WQSARVIRKVRPDVVLGMGGYPAFPGGMMASLLARPLLIHEQNSIPGLANRILSRLADRVLLGFPDAIKSEKKAVFCGNP
VRDEITRLAPPAQRYAGRSGSIKLLVVGGSLGAQALNTIVPRALKRIPEGMRPQVTHQAGARHLEALKQNYSEAGVEGEL
VTFIDNMASRYGESDLVICRAGALTVSELAAAGVASILVPFPYAVDDHQSTNAKFLSGKGAAILLPQSQLTPEGLAELLV
GMSRGQLMEMACRARELAQPDATRCVAETCMQMVAV

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=346, Percent_Identity=45.3757225433526, Blast_Score=289, Evalue=2e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_NITMU (Q2Y638)

Other databases:

- EMBL:   CP000103
- RefSeq:   YP_413175.1
- ProteinModelPortal:   Q2Y638
- SMR:   Q2Y638
- STRING:   Q2Y638
- GeneID:   3786753
- GenomeReviews:   CP000103_GR
- KEGG:   nmu:Nmul_A2494
- eggNOG:   COG0707
- HOGENOM:   HBG617076
- OMA:   IGFGGYP
- PhylomeDB:   Q2Y638
- ProtClustDB:   PRK00726
- BioCyc:   NMUL323848:NMUL_A2494-MONOMER
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 38219; Mature: 38088

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHTILIMAGGTGGHVFPGLAVAEYLKAAGWRIVWLGTEGGMETTLARQQGHALETIRFS
CCCEEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHCCCHHHHHEEC
GLRGKNVRTWLLLPARLLLAFWQSARVIRKVRPDVVLGMGGYPAFPGGMMASLLARPLLI
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHCCCEE
HEQNSIPGLANRILSRLADRVLLGFPDAIKSEKKAVFCGNPVRDEITRLAPPAQRYAGRS
ECCCCCCHHHHHHHHHHHHHHHHCCCHHHHCCCCEEEECCCHHHHHHHCCCCHHHHCCCC
GSIKLLVVGGSLGAQALNTIVPRALKRIPEGMRPQVTHQAGARHLEALKQNYSEAGVEGE
CCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCH
LVTFIDNMASRYGESDLVICRAGALTVSELAAAGVASILVPFPYAVDDHQSTNAKFLSGK
HHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCC
GAAILLPQSQLTPEGLAELLVGMSRGQLMEMACRARELAQPDATRCVAETCMQMVAV
CCEEEECCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SHTILIMAGGTGGHVFPGLAVAEYLKAAGWRIVWLGTEGGMETTLARQQGHALETIRFS
CCEEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHCCCHHHHHEEC
GLRGKNVRTWLLLPARLLLAFWQSARVIRKVRPDVVLGMGGYPAFPGGMMASLLARPLLI
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHCCCEE
HEQNSIPGLANRILSRLADRVLLGFPDAIKSEKKAVFCGNPVRDEITRLAPPAQRYAGRS
ECCCCCCHHHHHHHHHHHHHHHHCCCHHHHCCCCEEEECCCHHHHHHHCCCCHHHHCCCC
GSIKLLVVGGSLGAQALNTIVPRALKRIPEGMRPQVTHQAGARHLEALKQNYSEAGVEGE
CCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCH
LVTFIDNMASRYGESDLVICRAGALTVSELAAAGVASILVPFPYAVDDHQSTNAKFLSGK
HHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCC
GAAILLPQSQLTPEGLAELLVGMSRGQLMEMACRARELAQPDATRCVAETCMQMVAV
CCEEEECCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA