BacMap

Definition	Nitrosospira multiformis ATCC 25196 chromosome, complete genome.
Accession	NC_007614
Length	3,184,243

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The map label for this gene is ucpA [C]

Identifier: 82703568

GI number: 82703568

Start: 2803600

End: 2804385

Strand: Reverse

Name: ucpA [C]

Synonym: Nmul_A2453

Alternate gene names: 82703568

Gene position: 2804385-2803600 (Counterclockwise)

Preceding gene: 82703569

Following gene: 82703567

Centisome position: 88.07

GC content: 57.25

Gene sequence:

>786_bases
TTGACCCTGAAAGTCATCATCAGTGGCGCCTCCACCGGCCTCGGGAGGGCGTTGGCGCGCCGTTATGCCGACAGCGGCGC
AACGCTTGGCCTGATTGCTCGCCGGGTGGATTTGCTGGAGAGCCTCGTGGCGGAGAGGGCGGAAGCGAAGGTATCTCTCT
ACGTCGCGGATGTGCGTGATGCTGCTGCCCTGCGGACTGCGGCAGAAGATTTTATCGTCCGCCATGGTTGTCCCGATATC
GTCATCGCCAACGCGGGCATCAGTCACGGCACCCTTACCGAATGTGCCGAAGACAAGGAGGTTTTTGAGGATATTCTCAC
CACGAATGTTATCGGTATGGTGAACCTCTTCCAGCCCTTTGTTTCAGTCATGCGCACAGTCGGACAGGGTAGTCTGGTAG
GAATTGCAAGTGTCGCCGGCTATCGCGGCCTGCCCGGCAGCGGCGCCTATTCGGCTTCCAAGGCAGCTGCAATCAGCTAC
CTGGAGAGCCTCCGGGTGGAATTGCACGGAAGCGGCCTATCCGTCATAACCATTTGCCCCGGCTATGTCGTAACGCCCAT
GACAGTCGATAATCCCTTCCCCATGCCCTTCATCCTGACCGCTGAAGCCGCCGCCCGGAAGATCGTCGGCATTATCGAGC
GCAAGAAATCGTTTGCCGTAATACCTTGGCAAATGGCAATTGTCGCCCGGGTCTTGCGGTTGCTTCCCAATTTCCTGTAC
GACCGGCTATTCGCCAATGCACCGCATAAGCCTCGCATAAGCTATAAAGACCACAAAGAAAATTAG

Upstream 100 bases:

>100_bases
GAGTGGCAGAATGGGCAGTACGCCGGACGATACCATTCGGACAATGGAAGAGTTGATACAGAAAGTGCGCAAGGAACGGA
CTGGAAAATAGCTTCTTCCG

Downstream 100 bases:

>100_bases
TAGATTCCCGATTGATTTGCGCGGGGGAAACCCCATTTAACCGATTAAGTGATTGACCGGTGTAGTCAGTCCGTCGAACC
GGGTTTATATAACGTAGAGG

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MTLKVIISGASTGLGRALARRYADSGATLGLIARRVDLLESLVAERAEAKVSLYVADVRDAAALRTAAEDFIVRHGCPDI
VIANAGISHGTLTECAEDKEVFEDILTTNVIGMVNLFQPFVSVMRTVGQGSLVGIASVAGYRGLPGSGAYSASKAAAISY
LESLRVELHGSGLSVITICPGYVVTPMTVDNPFPMPFILTAEAAARKIVGIIERKKSFAVIPWQMAIVARVLRLLPNFLY
DRLFANAPHKPRISYKDHKEN

Sequences:

>Translated_261_residues
MTLKVIISGASTGLGRALARRYADSGATLGLIARRVDLLESLVAERAEAKVSLYVADVRDAAALRTAAEDFIVRHGCPDI
VIANAGISHGTLTECAEDKEVFEDILTTNVIGMVNLFQPFVSVMRTVGQGSLVGIASVAGYRGLPGSGAYSASKAAAISY
LESLRVELHGSGLSVITICPGYVVTPMTVDNPFPMPFILTAEAAARKIVGIIERKKSFAVIPWQMAIVARVLRLLPNFLY
DRLFANAPHKPRISYKDHKEN
>Mature_260_residues
TLKVIISGASTGLGRALARRYADSGATLGLIARRVDLLESLVAERAEAKVSLYVADVRDAAALRTAAEDFIVRHGCPDIV
IANAGISHGTLTECAEDKEVFEDILTTNVIGMVNLFQPFVSVMRTVGQGSLVGIASVAGYRGLPGSGAYSASKAAAISYL
ESLRVELHGSGLSVITICPGYVVTPMTVDNPFPMPFILTAEAAARKIVGIIERKKSFAVIPWQMAIVARVLRLLPNFLYD
RLFANAPHKPRISYKDHKEN

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI20149619, Length=270, Percent_Identity=29.6296296296296, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI40807363, Length=243, Percent_Identity=30.4526748971193, Blast_Score=81, Evalue=9e-16,
Organism=Homo sapiens, GI142976729, Length=258, Percent_Identity=26.7441860465116, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI7706318, Length=188, Percent_Identity=31.9148936170213, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI310128830, Length=246, Percent_Identity=30.0813008130081, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI310115468, Length=246, Percent_Identity=30.0813008130081, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI157739938, Length=191, Percent_Identity=28.2722513089005, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI210032110, Length=239, Percent_Identity=27.1966527196653, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI31543615, Length=230, Percent_Identity=25.6521739130435, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI226371731, Length=253, Percent_Identity=25.296442687747, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI223718074, Length=187, Percent_Identity=34.2245989304813, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI87082100, Length=209, Percent_Identity=33.4928229665072, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1787820, Length=181, Percent_Identity=29.8342541436464, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1787335, Length=191, Percent_Identity=29.3193717277487, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1786701, Length=263, Percent_Identity=26.9961977186312, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1787526, Length=188, Percent_Identity=28.7234042553192, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1786812, Length=213, Percent_Identity=28.6384976525822, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17567345, Length=271, Percent_Identity=27.6752767527675, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17508895, Length=243, Percent_Identity=30.4526748971193, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17564282, Length=243, Percent_Identity=29.6296296296296, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI193203117, Length=243, Percent_Identity=30.0411522633745, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI193203115, Length=243, Percent_Identity=30.0411522633745, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71997402, Length=275, Percent_Identity=27.2727272727273, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17570069, Length=188, Percent_Identity=29.2553191489362, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI115534660, Length=187, Percent_Identity=26.7379679144385, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17562990, Length=189, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17559104, Length=189, Percent_Identity=30.6878306878307, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI32563809, Length=196, Percent_Identity=29.5918367346939, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17507613, Length=196, Percent_Identity=29.5918367346939, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17538182, Length=202, Percent_Identity=30.6930693069307, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17563726, Length=254, Percent_Identity=25.9842519685039, Blast_Score=64, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=192, Percent_Identity=32.2916666666667, Blast_Score=89, Evalue=9e-19,
Organism=Saccharomyces cerevisiae, GI6320089, Length=203, Percent_Identity=27.5862068965517, Blast_Score=65, Evalue=9e-12,
Organism=Drosophila melanogaster, GI23397609, Length=186, Percent_Identity=33.8709677419355, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI21358495, Length=201, Percent_Identity=31.8407960199005, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24644339, Length=188, Percent_Identity=29.7872340425532, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI116007236, Length=221, Percent_Identity=30.316742081448, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI17737361, Length=200, Percent_Identity=33, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI21357041, Length=188, Percent_Identity=28.1914893617021, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24641232, Length=201, Percent_Identity=30.3482587064677, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24639444, Length=186, Percent_Identity=28.494623655914, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24580925, Length=194, Percent_Identity=32.9896907216495, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI28571526, Length=188, Percent_Identity=29.7872340425532, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28571387, Length=198, Percent_Identity=34.3434343434343, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24640492, Length=244, Percent_Identity=27.8688524590164, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24649181, Length=252, Percent_Identity=24.2063492063492, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI21355631, Length=265, Percent_Identity=26.4150943396226, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21355319, Length=187, Percent_Identity=26.2032085561497, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI281364494, Length=203, Percent_Identity=30.5418719211823, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI116007238, Length=175, Percent_Identity=31.4285714285714, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24643142, Length=187, Percent_Identity=28.3422459893048, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24581726, Length=200, Percent_Identity=28, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 28013; Mature: 27882

Theoretical pI: Translated: 9.08; Mature: 9.08

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLKVIISGASTGLGRALARRYADSGATLGLIARRVDLLESLVAERAEAKVSLYVADVRD
CEEEEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCEEEEEEECHHH
AAALRTAAEDFIVRHGCPDIVIANAGISHGTLTECAEDKEVFEDILTTNVIGMVNLFQPF
HHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSVMRTVGQGSLVGIASVAGYRGLPGSGAYSASKAAAISYLESLRVELHGSGLSVITICP
HHHHHHHCCCCEEEHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHEECCCCEEEEEECC
GYVVTPMTVDNPFPMPFILTAEAAARKIVGIIERKKSFAVIPWQMAIVARVLRLLPNFLY
CEEECCEECCCCCCCCEEEECHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHH
DRLFANAPHKPRISYKDHKEN
HHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TLKVIISGASTGLGRALARRYADSGATLGLIARRVDLLESLVAERAEAKVSLYVADVRD
EEEEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCEEEEEEECHHH
AAALRTAAEDFIVRHGCPDIVIANAGISHGTLTECAEDKEVFEDILTTNVIGMVNLFQPF
HHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSVMRTVGQGSLVGIASVAGYRGLPGSGAYSASKAAAISYLESLRVELHGSGLSVITICP
HHHHHHHCCCCEEEHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHEECCCCEEEEEECC
GYVVTPMTVDNPFPMPFILTAEAAARKIVGIIERKKSFAVIPWQMAIVARVLRLLPNFLY
CEEECCEECCCCCCCCEEEECHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHH
DRLFANAPHKPRISYKDHKEN
HHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1730672 [H]