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The map label for this gene is dsbC [H]

Identifier: 82703560

GI number: 82703560

Start: 2793326

End: 2794045

Strand: Direct

Name: dsbC [H]

Synonym: Nmul_A2445

Alternate gene names: 82703560

Gene position: 2793326-2794045 (Clockwise)

Preceding gene: 82703559

Following gene: 82703562

Centisome position: 87.72

GC content: 49.86

Gene sequence:

>720_bases
ATGCGTTCAAAACTCGTTTCCCTCGCTTTGCCTTCTCTATTGCTATGCTTTCTTTCCAGCGCTTCCGCTGACGAGGCATC
CCTGAAAAAAGCGCTTCAGGCAAATTTTCCCGGAGAGAAGGTCGAAAGCATAAAAAAAACCCCCTATCTCGGTCTATACG
AAGTGGTGGTGGGAGGCGAATTGTTCTATACGGACGACAAGGCTTCGTACCTTTTTTTCGGTCATGTAATTGATCCGAAA
ACGAAGGAAAGCCTGACTTCCGAACGCTTGCAACAAATCAAGGAGGCTCGGCGCATAGATGTAGGCTCTCTTCCCCTGCA
GCATGCGATCAAGGCGGTCAAGGGGAATGGGAAACGCAAACTTGTCGTTTTCTCCGATCCGAACTGCCCTTTTTGCAAAC
GTCTGGAAAAGGAACTGGTTAACGTAACGGATGTAACGATATATACCCTGCTTTATCCAGTGCTGAACGGTTCGACCCCG
ACCGCAACGGCGATATGGTGCTCGGAGGACAGGCTCAAGGCCTGGGAAGATTTCATGCTCAGGAATATCATGCCCGCCAG
CAAGGATTGCGCCACGCCCATAGATGTGATTCTCAAGGCAGGGAAAGAAAACGATATAAGCGGTACCCCTACCCTGATTT
TTGCCAATGGCTCGGTAACGCCCGGATTGATTCCTGCGGAGACGATAGAAAAGAAATTAAACGCGGCTCCTGCGAAATAG

Upstream 100 bases:

>100_bases
GAGCCCGGCTGATTCTTTTTCCTTTCCATCCCATCAGAACACCACCTACACAACTACGGGGCCGTCCGGCTGCATCCCAT
CCCAAAACGGAGTAAAGACC

Downstream 100 bases:

>100_bases
ATAACTCGGTGACAGGCGCTGGGAAGCGCCTGCATCCTCCTATTCGCGGGTTTATTTGGAGCTTCCCAGTATTCGCGCGG
CGGGTGGAAAGTCTTGGGGC

Product: putative thiol:disulfide interchange protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MRSKLVSLALPSLLLCFLSSASADEASLKKALQANFPGEKVESIKKTPYLGLYEVVVGGELFYTDDKASYLFFGHVIDPK
TKESLTSERLQQIKEARRIDVGSLPLQHAIKAVKGNGKRKLVVFSDPNCPFCKRLEKELVNVTDVTIYTLLYPVLNGSTP
TATAIWCSEDRLKAWEDFMLRNIMPASKDCATPIDVILKAGKENDISGTPTLIFANGSVTPGLIPAETIEKKLNAAPAK

Sequences:

>Translated_239_residues
MRSKLVSLALPSLLLCFLSSASADEASLKKALQANFPGEKVESIKKTPYLGLYEVVVGGELFYTDDKASYLFFGHVIDPK
TKESLTSERLQQIKEARRIDVGSLPLQHAIKAVKGNGKRKLVVFSDPNCPFCKRLEKELVNVTDVTIYTLLYPVLNGSTP
TATAIWCSEDRLKAWEDFMLRNIMPASKDCATPIDVILKAGKENDISGTPTLIFANGSVTPGLIPAETIEKKLNAAPAK
>Mature_239_residues
MRSKLVSLALPSLLLCFLSSASADEASLKKALQANFPGEKVESIKKTPYLGLYEVVVGGELFYTDDKASYLFFGHVIDPK
TKESLTSERLQQIKEARRIDVGSLPLQHAIKAVKGNGKRKLVVFSDPNCPFCKRLEKELVNVTDVTIYTLLYPVLNGSTP
TATAIWCSEDRLKAWEDFMLRNIMPASKDCATPIDVILKAGKENDISGTPTLIFANGSVTPGLIPAETIEKKLNAAPAK

Specific function: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process [H]

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioredoxin family. DsbC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789260, Length=231, Percent_Identity=24.6753246753247, Blast_Score=78, Evalue=6e-16,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018950
- InterPro:   IPR009094
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10411 DsbC_N [H]

EC number: 5.3.4.1

Molecular weight: Translated: 26160; Mature: 26160

Theoretical pI: Translated: 8.69; Mature: 8.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSKLVSLALPSLLLCFLSSASADEASLKKALQANFPGEKVESIKKTPYLGLYEVVVGGE
CCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHEECCE
LFYTDDKASYLFFGHVIDPKTKESLTSERLQQIKEARRIDVGSLPLQHAIKAVKGNGKRK
EEEECCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCEE
LVVFSDPNCPFCKRLEKELVNVTDVTIYTLLYPVLNGSTPTATAIWCSEDRLKAWEDFML
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHH
RNIMPASKDCATPIDVILKAGKENDISGTPTLIFANGSVTPGLIPAETIEKKLNAAPAK
HHCCCCCCCCCCHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCC
>Mature Secondary Structure
MRSKLVSLALPSLLLCFLSSASADEASLKKALQANFPGEKVESIKKTPYLGLYEVVVGGE
CCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHEECCE
LFYTDDKASYLFFGHVIDPKTKESLTSERLQQIKEARRIDVGSLPLQHAIKAVKGNGKRK
EEEECCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCEE
LVVFSDPNCPFCKRLEKELVNVTDVTIYTLLYPVLNGSTPTATAIWCSEDRLKAWEDFML
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHH
RNIMPASKDCATPIDVILKAGKENDISGTPTLIFANGSVTPGLIPAETIEKKLNAAPAK
HHCCCCCCCCCCHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12910271 [H]