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The map label for this gene is resE [H]

Identifier: 82703525

GI number: 82703525

Start: 2746403

End: 2747938

Strand: Reverse

Name: resE [H]

Synonym: Nmul_A2410

Alternate gene names: 82703525

Gene position: 2747938-2746403 (Counterclockwise)

Preceding gene: 82703526

Following gene: 82703521

Centisome position: 86.3

GC content: 48.96

Gene sequence:

>1536_bases
ATGGCGGTTGTCGAGTTTTCCTGGAATCTGTCCGACAGAAATCGCTTCGCGCTTCCCGGAGTGGGGACAAACGGCGCGAA
GCTCAGCGATGAAGTATTAATCAATAATGCCCGATGGTTTATTATCTTTCGATGGGGTGTTATCGGGGTTCTTCTGCTTT
TTCAGGTATTCGCGCTCATTGCCTCGGATGAGCTTACGAAAATCGGCATTACTCACCAGCAAGGATGGCCGCTTGCGGTA
ACGTTGGTATTATTCATTGCAAACGTCATTTACATTCAAGCTCTGGATTTTCAGCGGCAAACAAAATATAACTCGCCCGC
TATAAATATCTGGGCCCAGATCATTGTCGATCTTCTGTGTCTGTCGGTAGTAGTGCATTTTATCGGCAGCATCGCGACGC
CCGCTCCCTTCTTTTATGTGCTGCATATTGCGCTGGCGTGCATCTTTTTCTCGACCCTGGAAAGCCTGGTGGTGACTGTC
GTGGTATGCGTCATGTACGCCACTGTTCTGCTGGATGAGCATCCGCTTCTTTTTATGGCACCGCAAGCGCTGGCAATCGA
TCCTGGCATATCTGTTCTGAGTCCGCTCAAGATCAATATTTTCCTGTGGATGTTTACGCTCGATGTGCTCTTTATCACTG
TCTGGTATGTCGTCTCAAGGCTGGCGATTGTAGTGCGCATTCATGAGCACAACCTTGTCGATGCCTACGAGGAAATCAGG
CGGGCGCAAGTGGAGAAAGATCGGTACGCCGTGCTGATGACTCATCAACTCAAAGCCCCGCTCGATGCTATCCGCAGCAA
GATAAGCCTCATAAAAGGAGAATATTGCGGGGAGGTATCGCCCGAAATAAGAGAAGTGATATCGAAGATCGATTATCGCG
CTTCCGGCATGGCGAGCCTCATTCTGGATGTCCTCAAGCTGGAACGGTTGAAAGCCGCCGCACGTGACAACAACGCAAGA
GAGCAGATCAGCATTGGAATAGTAATCCGCAAATGCATCGATAAGTTAAAACCGATCGCCAGTTCCCGCCATATCGACGT
AAAAGTATCGCTCCAGGACTTCGCCGTTGAAGGTATTCCCAATCAGCTTGAAATACTGCTTGAAAATGTCATTTCAAACG
CCATCGCTTATTCGTATGACAACTCAACGGTAGAAATTGTAGCTGCCGTTGAAGGCGCAGGTTCCTACGGTACCGTAACC
GTTATCGATCATGGGATAGGGATCGGCGAAAAAGATCTGCCGCATATTTTCGATGAATACTTTTACACTCCGCGAGCGGC
ACTGCATAACAGGACTTCAAGCGGGATAGGCTTATCGATCGTCAAGACAGTGGCCGAAAACAACAAACTACAGATCAGGA
TTTCCAGCGAACAGAATGTCGGGACAACTTTTTCCGTTATTTTCCCCACGATAACATCGGTATCCATTCCTAAAACGGAG
GCACGCTCGGAAGCCTCAAGTTCGCATCTTGCAAACTCACAAAGCCGCCCACTCGACTCCCAGAAAGACGGAAACGAACT
CGCTTCCACTCATTGA

Upstream 100 bases:

>100_bases
ATCATGGAAAAACCGGTCGAGCCCGTCAGTTTCTTATCGATCATTCATAACCGGCTGGAGAATAAGGAACCCTGAAGCAG
AATTTCCGGAGACTTTAACC

Downstream 100 bases:

>100_bases
AACATGTCCTCTCCCATTTGGCGGAGAGAGGACAGGGAGAGGGAAGGCAAAGGAAAAGATTGGGTGCATCACGACATCGG
TTCCGATACCCATTTCTTTC

Product: periplasmic sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 511; Mature: 510

Protein sequence:

>511_residues
MAVVEFSWNLSDRNRFALPGVGTNGAKLSDEVLINNARWFIIFRWGVIGVLLLFQVFALIASDELTKIGITHQQGWPLAV
TLVLFIANVIYIQALDFQRQTKYNSPAINIWAQIIVDLLCLSVVVHFIGSIATPAPFFYVLHIALACIFFSTLESLVVTV
VVCVMYATVLLDEHPLLFMAPQALAIDPGISVLSPLKINIFLWMFTLDVLFITVWYVVSRLAIVVRIHEHNLVDAYEEIR
RAQVEKDRYAVLMTHQLKAPLDAIRSKISLIKGEYCGEVSPEIREVISKIDYRASGMASLILDVLKLERLKAAARDNNAR
EQISIGIVIRKCIDKLKPIASSRHIDVKVSLQDFAVEGIPNQLEILLENVISNAIAYSYDNSTVEIVAAVEGAGSYGTVT
VIDHGIGIGEKDLPHIFDEYFYTPRAALHNRTSSGIGLSIVKTVAENNKLQIRISSEQNVGTTFSVIFPTITSVSIPKTE
ARSEASSSHLANSQSRPLDSQKDGNELASTH

Sequences:

>Translated_511_residues
MAVVEFSWNLSDRNRFALPGVGTNGAKLSDEVLINNARWFIIFRWGVIGVLLLFQVFALIASDELTKIGITHQQGWPLAV
TLVLFIANVIYIQALDFQRQTKYNSPAINIWAQIIVDLLCLSVVVHFIGSIATPAPFFYVLHIALACIFFSTLESLVVTV
VVCVMYATVLLDEHPLLFMAPQALAIDPGISVLSPLKINIFLWMFTLDVLFITVWYVVSRLAIVVRIHEHNLVDAYEEIR
RAQVEKDRYAVLMTHQLKAPLDAIRSKISLIKGEYCGEVSPEIREVISKIDYRASGMASLILDVLKLERLKAAARDNNAR
EQISIGIVIRKCIDKLKPIASSRHIDVKVSLQDFAVEGIPNQLEILLENVISNAIAYSYDNSTVEIVAAVEGAGSYGTVT
VIDHGIGIGEKDLPHIFDEYFYTPRAALHNRTSSGIGLSIVKTVAENNKLQIRISSEQNVGTTFSVIFPTITSVSIPKTE
ARSEASSSHLANSQSRPLDSQKDGNELASTH
>Mature_510_residues
AVVEFSWNLSDRNRFALPGVGTNGAKLSDEVLINNARWFIIFRWGVIGVLLLFQVFALIASDELTKIGITHQQGWPLAVT
LVLFIANVIYIQALDFQRQTKYNSPAINIWAQIIVDLLCLSVVVHFIGSIATPAPFFYVLHIALACIFFSTLESLVVTVV
VCVMYATVLLDEHPLLFMAPQALAIDPGISVLSPLKINIFLWMFTLDVLFITVWYVVSRLAIVVRIHEHNLVDAYEEIRR
AQVEKDRYAVLMTHQLKAPLDAIRSKISLIKGEYCGEVSPEIREVISKIDYRASGMASLILDVLKLERLKAAARDNNARE
QISIGIVIRKCIDKLKPIASSRHIDVKVSLQDFAVEGIPNQLEILLENVISNAIAYSYDNSTVEIVAAVEGAGSYGTVTV
IDHGIGIGEKDLPHIFDEYFYTPRAALHNRTSSGIGLSIVKTVAENNKLQIRISSEQNVGTTFSVIFPTITSVSIPKTEA
RSEASSSHLANSQSRPLDSQKDGNELASTH

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=282, Percent_Identity=24.822695035461, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788713, Length=251, Percent_Identity=23.5059760956175, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI87082128, Length=234, Percent_Identity=23.9316239316239, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1790861, Length=216, Percent_Identity=26.8518518518519, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790436, Length=246, Percent_Identity=24.7967479674797, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1790346, Length=215, Percent_Identity=26.046511627907, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1789149, Length=239, Percent_Identity=24.6861924686192, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1786783, Length=237, Percent_Identity=22.7848101265823, Blast_Score=63, Evalue=5e-11,
Organism=Escherichia coli, GI1786600, Length=247, Percent_Identity=21.4574898785425, Blast_Score=63, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 56598; Mature: 56467

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVVEFSWNLSDRNRFALPGVGTNGAKLSDEVLINNARWFIIFRWGVIGVLLLFQVFALI
CEEEEEEECCCCCCEEECCCCCCCCCCCCCCEEEECCEEEEEEHHHHHHHHHHHHHHHHH
ASDELTKIGITHQQGWPLAVTLVLFIANVIYIQALDFQRQTKYNSPAINIWAQIIVDLLC
HCCCHHEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCHHHHHHHHHHHHHH
LSVVVHFIGSIATPAPFFYVLHIALACIFFSTLESLVVTVVVCVMYATVLLDEHPLLFMA
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEC
PQALAIDPGISVLSPLKINIFLWMFTLDVLFITVWYVVSRLAIVVRIHEHNLVDAYEEIR
CCCEEECCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCHHHHHHHHH
RAQVEKDRYAVLMTHQLKAPLDAIRSKISLIKGEYCGEVSPEIREVISKIDYRASGMASL
HHHHCCCCEEEEEHHHHHCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCHHHH
ILDVLKLERLKAAARDNNAREQISIGIVIRKCIDKLKPIASSRHIDVKVSLQDFAVEGIP
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHCCCC
NQLEILLENVISNAIAYSYDNSTVEIVAAVEGAGSYGTVTVIDHGIGIGEKDLPHIFDEY
HHHHHHHHHHHHHHHEEECCCCEEEEEEEEECCCCCCEEEEEECCCCCCCCCHHHHHHHH
FYTPRAALHNRTSSGIGLSIVKTVAENNKLQIRISSEQNVGTTFSVIFPTITSVSIPKTE
HCCCHHHHCCCCCCCCCHHHHHHHHCCCEEEEEECCCCCCCCEEEEEHHHHCCCCCCCHH
ARSEASSSHLANSQSRPLDSQKDGNELASTH
HHHHHHHHHHCCCCCCCCCCCCCCCHHCCCC
>Mature Secondary Structure 
AVVEFSWNLSDRNRFALPGVGTNGAKLSDEVLINNARWFIIFRWGVIGVLLLFQVFALI
EEEEEEECCCCCCEEECCCCCCCCCCCCCCEEEECCEEEEEEHHHHHHHHHHHHHHHHH
ASDELTKIGITHQQGWPLAVTLVLFIANVIYIQALDFQRQTKYNSPAINIWAQIIVDLLC
HCCCHHEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCHHHHHHHHHHHHHH
LSVVVHFIGSIATPAPFFYVLHIALACIFFSTLESLVVTVVVCVMYATVLLDEHPLLFMA
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEC
PQALAIDPGISVLSPLKINIFLWMFTLDVLFITVWYVVSRLAIVVRIHEHNLVDAYEEIR
CCCEEECCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCHHHHHHHHH
RAQVEKDRYAVLMTHQLKAPLDAIRSKISLIKGEYCGEVSPEIREVISKIDYRASGMASL
HHHHCCCCEEEEEHHHHHCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCHHHH
ILDVLKLERLKAAARDNNAREQISIGIVIRKCIDKLKPIASSRHIDVKVSLQDFAVEGIP
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHCCCC
NQLEILLENVISNAIAYSYDNSTVEIVAAVEGAGSYGTVTVIDHGIGIGEKDLPHIFDEY
HHHHHHHHHHHHHHHEEECCCCEEEEEEEEECCCCCCEEEEEECCCCCCCCCHHHHHHHH
FYTPRAALHNRTSSGIGLSIVKTVAENNKLQIRISSEQNVGTTFSVIFPTITSVSIPKTE
HCCCHHHHCCCCCCCCCHHHHHHHHCCCEEEEEECCCCCCCCEEEEEHHHHCCCCCCCHH
ARSEASSSHLANSQSRPLDSQKDGNELASTH
HHHHHHHHHHCCCCCCCCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]