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The map label for this gene is galE [C]

Identifier: 82703519

GI number: 82703519

Start: 2741733

End: 2742656

Strand: Direct

Name: galE [C]

Synonym: Nmul_A2404

Alternate gene names: 82703519

Gene position: 2741733-2742656 (Clockwise)

Preceding gene: 82703518

Following gene: 82703522

Centisome position: 86.1

GC content: 47.62

Gene sequence:

>924_bases
GTGATCTTTGGCGGCGGCGGTTTCATCGGCTCTGCAATCGTTGACAGACTGCTTCTCGATGGCCATGAATTGACGATCTT
CGAGCGGCCGAGAGTGGAACCCTATCGCAAATTTCTGGATACTGAGCCTGTGAAATGGTTAACCGGCGATTTATTAAGCA
CACACGACGTTGGCGATGCAATAGACGGGATGGATATCGTGATACATCTCGTCTCCTCCACCCTGCCCAAGAGCTCGAAT
GATGATCCCATTTACGATGTTCAGAGCAACCTAGTAGGATCGTTGCAAATGCTGAACGTTATGGTCGCCAAAAAAATAAG
GAAGATTATCTTCATTTCGTCAGGTGGAACCGTATACGGGAGGCCAGAGTATTTACCCATTGATGAGCGTCACCCCACAG
CGCCCCAAGTTTCCTACGGCATTACCAAGCTTGCAATTGAGAAATATCTTTTACTCTTCGAACAAATGCATGGCATCAAG
ACTACCATTCTTCGAGTGGCTAACCCTTTCGGCGAACGTCAGCGCATCGAAACCGCTCAAGGGGCCGTTAGTGCTTTCCT
TCACAGGGCCTTAAGCGGACAGCCAATCGAAATATGGGGAGATGGAACCGCTACCCGAGATTATATTTACATTAGCGATG
TAGCTGACGCGTTTGCACGTACCGTAACTTATGAAGGCCCACAAAGCGTTTTCAATATTAGCTCCGGAGCGGGAACCAGC
CTTAATGAACTTGTTTCCCTGCTTGAAGAAATTCTCGGTCATACGATTGAGTGCCGCTATCTGTCTGGGCGTAGTTTTGA
TGTGCAAGTCAGTATCTTAAGTAACACCCTCGCACAACAGGAAATGGGTTGGATGCCAAAGGTTCCTTTACGAGAGGGAA
TTGAAAATGTTGTCAAATGGATGATTAAAACCCGAGGAAAGTGA

Upstream 100 bases:

>100_bases
TTGCACGCTCTTGAAAGATTGCTTCCATTGATAGCAGCAAAGCAATCAACTCGTTCTGTATTAACTAACGTAACAGGCGT
AACGAGATAACGTGAAAATA

Downstream 100 bases:

>100_bases
TAGCGAGAATGCTTGTGAAGCAGCCACGCGAGATGTGGAGTTGCCCCTATTAAACCGGACAAGATGCGGTTAGTAACTGG
CTGCGGATGAATTGTCGTGG

Product: NAD-dependent epimerase/dehydratase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MIFGGGGFIGSAIVDRLLLDGHELTIFERPRVEPYRKFLDTEPVKWLTGDLLSTHDVGDAIDGMDIVIHLVSSTLPKSSN
DDPIYDVQSNLVGSLQMLNVMVAKKIRKIIFISSGGTVYGRPEYLPIDERHPTAPQVSYGITKLAIEKYLLLFEQMHGIK
TTILRVANPFGERQRIETAQGAVSAFLHRALSGQPIEIWGDGTATRDYIYISDVADAFARTVTYEGPQSVFNISSGAGTS
LNELVSLLEEILGHTIECRYLSGRSFDVQVSILSNTLAQQEMGWMPKVPLREGIENVVKWMIKTRGK

Sequences:

>Translated_307_residues
MIFGGGGFIGSAIVDRLLLDGHELTIFERPRVEPYRKFLDTEPVKWLTGDLLSTHDVGDAIDGMDIVIHLVSSTLPKSSN
DDPIYDVQSNLVGSLQMLNVMVAKKIRKIIFISSGGTVYGRPEYLPIDERHPTAPQVSYGITKLAIEKYLLLFEQMHGIK
TTILRVANPFGERQRIETAQGAVSAFLHRALSGQPIEIWGDGTATRDYIYISDVADAFARTVTYEGPQSVFNISSGAGTS
LNELVSLLEEILGHTIECRYLSGRSFDVQVSILSNTLAQQEMGWMPKVPLREGIENVVKWMIKTRGK
>Mature_307_residues
MIFGGGGFIGSAIVDRLLLDGHELTIFERPRVEPYRKFLDTEPVKWLTGDLLSTHDVGDAIDGMDIVIHLVSSTLPKSSN
DDPIYDVQSNLVGSLQMLNVMVAKKIRKIIFISSGGTVYGRPEYLPIDERHPTAPQVSYGITKLAIEKYLLLFEQMHGIK
TTILRVANPFGERQRIETAQGAVSAFLHRALSGQPIEIWGDGTATRDYIYISDVADAFARTVTYEGPQSVFNISSGAGTS
LNELVSLLEEILGHTIECRYLSGRSFDVQVSILSNTLAQQEMGWMPKVPLREGIENVVKWMIKTRGK

Specific function: Galactose metabolism; third step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI42516563, Length=311, Percent_Identity=27.9742765273312, Blast_Score=133, Evalue=2e-31,
Organism=Homo sapiens, GI56237023, Length=332, Percent_Identity=27.1084337349398, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI56118217, Length=332, Percent_Identity=27.1084337349398, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI189083684, Length=332, Percent_Identity=27.1084337349398, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI7657641, Length=316, Percent_Identity=23.7341772151899, Blast_Score=93, Evalue=4e-19,
Organism=Escherichia coli, GI1786974, Length=332, Percent_Identity=27.4096385542169, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI48994969, Length=354, Percent_Identity=23.1638418079096, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1788589, Length=337, Percent_Identity=22.2551928783383, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1788353, Length=338, Percent_Identity=23.0769230769231, Blast_Score=65, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17539532, Length=312, Percent_Identity=26.2820512820513, Blast_Score=122, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI71982035, Length=341, Percent_Identity=27.5659824046921, Blast_Score=98, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI71982038, Length=343, Percent_Identity=27.1137026239067, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17568069, Length=344, Percent_Identity=25, Blast_Score=78, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6319493, Length=338, Percent_Identity=24.2603550295858, Blast_Score=85, Evalue=1e-17,
Organism=Drosophila melanogaster, GI21356223, Length=309, Percent_Identity=25.2427184466019, Blast_Score=111, Evalue=5e-25,
Organism=Drosophila melanogaster, GI19923002, Length=334, Percent_Identity=25.4491017964072, Blast_Score=92, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 34042; Mature: 34042

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFGGGGFIGSAIVDRLLLDGHELTIFERPRVEPYRKFLDTEPVKWLTGDLLSTHDVGDA
CEECCCCHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHCCCCCHHHHHHHHHHCCCCCH
IDGMDIVIHLVSSTLPKSSNDDPIYDVQSNLVGSLQMLNVMVAKKIRKIIFISSGGTVYG
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCEECC
RPEYLPIDERHPTAPQVSYGITKLAIEKYLLLFEQMHGIKTTILRVANPFGERQRIETAQ
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
GAVSAFLHRALSGQPIEIWGDGTATRDYIYISDVADAFARTVTYEGPQSVFNISSGAGTS
HHHHHHHHHHHCCCCEEEECCCCCCCCEEEEHHHHHHHHHHHCCCCCHHHEECCCCCCCC
LNELVSLLEEILGHTIECRYLSGRSFDVQVSILSNTLAQQEMGWMPKVPLREGIENVVKW
HHHHHHHHHHHHCCEEEEEEECCCCEEEEEHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
MIKTRGK
HHHHCCC
>Mature Secondary Structure
MIFGGGGFIGSAIVDRLLLDGHELTIFERPRVEPYRKFLDTEPVKWLTGDLLSTHDVGDA
CEECCCCHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHCCCCCHHHHHHHHHHCCCCCH
IDGMDIVIHLVSSTLPKSSNDDPIYDVQSNLVGSLQMLNVMVAKKIRKIIFISSGGTVYG
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCEECC
RPEYLPIDERHPTAPQVSYGITKLAIEKYLLLFEQMHGIKTTILRVANPFGERQRIETAQ
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
GAVSAFLHRALSGQPIEIWGDGTATRDYIYISDVADAFARTVTYEGPQSVFNISSGAGTS
HHHHHHHHHHHCCCCEEEECCCCCCCCEEEEHHHHHHHHHHHCCCCCHHHEECCCCCCCC
LNELVSLLEEILGHTIECRYLSGRSFDVQVSILSNTLAQQEMGWMPKVPLREGIENVVKW
HHHHHHHHHHHHCCEEEEEEECCCCEEEEEHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
MIKTRGK
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]