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The map label for this gene is abcA [H]

Identifier: 82703513

GI number: 82703513

Start: 2731356

End: 2732822

Strand: Direct

Name: abcA [H]

Synonym: Nmul_A2398

Alternate gene names: 82703513

Gene position: 2731356-2732822 (Clockwise)

Preceding gene: 82703512

Following gene: 82703514

Centisome position: 85.78

GC content: 51.4

Gene sequence:

>1467_bases
ATGTTCTCTGAAGGAGAAAACGTCGCCAAAGCGACAATCCCGCTCGCTCTTGAATCAGCGGAGAAGAATCTCGAAACGAG
CAACGAAAATGAAAAGGCAAGGAGAAGTTCCAGTGATACCGCCATCAGTGTTCGTGGCATTTCAAAATGCTACCAAATCT
ATGACGCACCTCGCGATCGGCTAAAGCAATTCATCATCCCGCGTCTTCGCCTGGCGAGACAACAGTCTCGCCAGTATTTC
CGCGAGTTCTGGGCGCTCAAGGGTATCTCCTTTGAAGTAAGGAAAGGTGAAACGGTAGGCATCATTGGCCGTAATGGATC
AGGCAAATCTACGCTATTGCAGATAATCTGCGGCACCCTGACGCCGACGGCGGGAAGCGTAGAAACGAGGGGGCGCATTG
CCGCCTTGCTGGAGTTAGGCTCCGGCTTCAATCCCGAATTTACGGGACGTGAAAACATCTACATGAATGGCGCAGTACTT
GGATTGACTCGCGAGGAAATCGACGACCGCTTTGACTCGATCGTATCGTTTGCAGACATTGGGCAGTTCATCGACCAGCC
AGTCAAGACCTATTCGAGCGGCATGTCCGTGCGCCTTGCTTTTGCGGTGCAGGCTCAGGTTGATCCGGATATCCTGATCG
TGGACGAAGCACTCTCCGTGGGAGATGTAAGGTTCCAGGCCAAGTGTTTTGCACGCCTGCAGCAACTGAAAGATAACGGC
ACCAGCGTGTTGCTGGTCACTCATTCGAGCGAACAAATCGTCACTCACTGCTCCAGTGCGCTCCTGTTGAATGATGGCAT
GCAGTTTGAAATTGGCGAACCCCGGCACGTTGTAAACCGCTACCTCGACCTGCTGTTTGGCAAGGAAAGACGCAACCCCG
ACTCCCCCCAAGCCCAACCAGGAGATATATTTCAGGAAGACAAAGGATATGCTGAGTCTGCATATCAGCTAAGCACTGAC
AGCGACGTCTTTCAAACCCGCAATGGGTATAACACGCATGAGTATCGGTGGGGTGACGGCACCGCCTCCATTCTGGATTT
CTACCTTGCTGCGAATGGAGAACCCTATCCCTCAGCAATTACCGTGGGACAGACTGTCACCCTTGCAGTATCCATCAAAT
TCCACAGCGATATGTGGCGGCCCATATTGGGTATCACCATCAAGACCAAGGATGGCGTGACCATATCCGGTACCAACTCG
GAGATGGCCGACCTGCTAGACTTGCAGGCGCTCGTAAAGAAAGGAGCAATTCTGGTTGGCAAATGCAGTTTCCAATGCAG
ACTCGGTCCGGGTGATTATTTTGTTTCGCTCGGCCTTGCTACACGAGAAAATGACGAAATCATTCCGCACGATCGGCGTT
ACGATTCGATACATTTTATAGTTGAGCCACACAATAAATTCCATGGCTTGGCTGACCTCGCTCTTGACCTCTCGATTTCC
CATATAGTCGAATCAAATCAGATCTGA

Upstream 100 bases:

>100_bases
CTGCCGGACTTCGGTCACTGGAGCACCATGATGATTGCCTCCTTGCTGATGGCATGGGCAGGATTCGCCTGGTTTCAGAA
AACCCGCAAGGGATTTGCCG

Downstream 100 bases:

>100_bases
CGTTATCCCAAACTTTGCAAGCGACTGTTCATACTTGGTTTTTATGAAAAACCTCTCGCCAACTTATGTATTCGACATCC
AGGAACAACTCTGGTCTCGT

Product: ABC transporter-like protein

Products: ADP; phosphate; putrescine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 488; Mature: 488

Protein sequence:

>488_residues
MFSEGENVAKATIPLALESAEKNLETSNENEKARRSSSDTAISVRGISKCYQIYDAPRDRLKQFIIPRLRLARQQSRQYF
REFWALKGISFEVRKGETVGIIGRNGSGKSTLLQIICGTLTPTAGSVETRGRIAALLELGSGFNPEFTGRENIYMNGAVL
GLTREEIDDRFDSIVSFADIGQFIDQPVKTYSSGMSVRLAFAVQAQVDPDILIVDEALSVGDVRFQAKCFARLQQLKDNG
TSVLLVTHSSEQIVTHCSSALLLNDGMQFEIGEPRHVVNRYLDLLFGKERRNPDSPQAQPGDIFQEDKGYAESAYQLSTD
SDVFQTRNGYNTHEYRWGDGTASILDFYLAANGEPYPSAITVGQTVTLAVSIKFHSDMWRPILGITIKTKDGVTISGTNS
EMADLLDLQALVKKGAILVGKCSFQCRLGPGDYFVSLGLATRENDEIIPHDRRYDSIHFIVEPHNKFHGLADLALDLSIS
HIVESNQI

Sequences:

>Translated_488_residues
MFSEGENVAKATIPLALESAEKNLETSNENEKARRSSSDTAISVRGISKCYQIYDAPRDRLKQFIIPRLRLARQQSRQYF
REFWALKGISFEVRKGETVGIIGRNGSGKSTLLQIICGTLTPTAGSVETRGRIAALLELGSGFNPEFTGRENIYMNGAVL
GLTREEIDDRFDSIVSFADIGQFIDQPVKTYSSGMSVRLAFAVQAQVDPDILIVDEALSVGDVRFQAKCFARLQQLKDNG
TSVLLVTHSSEQIVTHCSSALLLNDGMQFEIGEPRHVVNRYLDLLFGKERRNPDSPQAQPGDIFQEDKGYAESAYQLSTD
SDVFQTRNGYNTHEYRWGDGTASILDFYLAANGEPYPSAITVGQTVTLAVSIKFHSDMWRPILGITIKTKDGVTISGTNS
EMADLLDLQALVKKGAILVGKCSFQCRLGPGDYFVSLGLATRENDEIIPHDRRYDSIHFIVEPHNKFHGLADLALDLSIS
HIVESNQI
>Mature_488_residues
MFSEGENVAKATIPLALESAEKNLETSNENEKARRSSSDTAISVRGISKCYQIYDAPRDRLKQFIIPRLRLARQQSRQYF
REFWALKGISFEVRKGETVGIIGRNGSGKSTLLQIICGTLTPTAGSVETRGRIAALLELGSGFNPEFTGRENIYMNGAVL
GLTREEIDDRFDSIVSFADIGQFIDQPVKTYSSGMSVRLAFAVQAQVDPDILIVDEALSVGDVRFQAKCFARLQQLKDNG
TSVLLVTHSSEQIVTHCSSALLLNDGMQFEIGEPRHVVNRYLDLLFGKERRNPDSPQAQPGDIFQEDKGYAESAYQLSTD
SDVFQTRNGYNTHEYRWGDGTASILDFYLAANGEPYPSAITVGQTVTLAVSIKFHSDMWRPILGITIKTKDGVTISGTNS
EMADLLDLQALVKKGAILVGKCSFQCRLGPGDYFVSLGLATRENDEIIPHDRRYDSIHFIVEPHNKFHGLADLALDLSIS
HIVESNQI

Specific function: Influences the expression of the surface array protein gene (vapA). May have both regulatory and transport activities [H]

COG id: COG1134

COG function: function code GM; ABC-type polysaccharide/polyol phosphate transport system, ATPase component

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI153792144, Length=247, Percent_Identity=27.9352226720648, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI31657092, Length=225, Percent_Identity=27.1111111111111, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI27436953, Length=202, Percent_Identity=29.2079207920792, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI6005701, Length=205, Percent_Identity=28.2926829268293, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI27262624, Length=210, Percent_Identity=27.1428571428571, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI27262626, Length=210, Percent_Identity=27.1428571428571, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI27477115, Length=208, Percent_Identity=28.8461538461538, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI30795238, Length=213, Percent_Identity=24.4131455399061, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI27881501, Length=213, Percent_Identity=24.4131455399061, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI150417984, Length=208, Percent_Identity=24.5192307692308, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI47078218, Length=283, Percent_Identity=21.5547703180212, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI45446740, Length=283, Percent_Identity=21.5547703180212, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI105990541, Length=254, Percent_Identity=24.4094488188976, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI157502201, Length=299, Percent_Identity=26.4214046822742, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI116734710, Length=210, Percent_Identity=23.3333333333333, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI157502203, Length=299, Percent_Identity=26.4214046822742, Blast_Score=71, Evalue=3e-12,
Organism=Escherichia coli, GI87081791, Length=240, Percent_Identity=24.5833333333333, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1789891, Length=211, Percent_Identity=28.436018957346, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1786319, Length=205, Percent_Identity=26.8292682926829, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790467, Length=234, Percent_Identity=24.7863247863248, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI87082267, Length=206, Percent_Identity=24.7572815533981, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI87081709, Length=224, Percent_Identity=24.1071428571429, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87081782, Length=209, Percent_Identity=24.4019138755981, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1788210, Length=202, Percent_Identity=27.7227722772277, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI48995001, Length=205, Percent_Identity=24.390243902439, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI87081834, Length=198, Percent_Identity=31.3131313131313, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1786703, Length=207, Percent_Identity=27.536231884058, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI48994943, Length=214, Percent_Identity=23.8317757009346, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1788165, Length=197, Percent_Identity=23.8578680203046, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1789593, Length=204, Percent_Identity=25.4901960784314, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI87082268, Length=203, Percent_Identity=25.615763546798, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1788761, Length=197, Percent_Identity=26.9035532994924, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17565586, Length=232, Percent_Identity=26.7241379310345, Blast_Score=96, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI115533608, Length=225, Percent_Identity=25.3333333333333, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17569081, Length=210, Percent_Identity=26.1904761904762, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71983523, Length=258, Percent_Identity=23.2558139534884, Blast_Score=66, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI71983516, Length=258, Percent_Identity=23.2558139534884, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI71983510, Length=258, Percent_Identity=23.2558139534884, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI28573571, Length=254, Percent_Identity=23.6220472440945, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI28573573, Length=254, Percent_Identity=23.6220472440945, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24666092, Length=287, Percent_Identity=23.3449477351916, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24643674, Length=289, Percent_Identity=22.4913494809689, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI116007184, Length=199, Percent_Identity=25.1256281407035, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI221500365, Length=199, Percent_Identity=25.1256281407035, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24648314, Length=214, Percent_Identity=26.6355140186916, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI221512771, Length=220, Percent_Identity=24.5454545454545, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI45550390, Length=196, Percent_Identity=27.0408163265306, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 54047; Mature: 54047

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSEGENVAKATIPLALESAEKNLETSNENEKARRSSSDTAISVRGISKCYQIYDAPRDR
CCCCCCCCEEEEEEEEEHHHHHCCCCCCCCHHHHCCCCCCEEEEHHHHHHHHHHCCCHHH
LKQFIIPRLRLARQQSRQYFREFWALKGISFEVRKGETVGIIGRNGSGKSTLLQIICGTL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCEEEEEECCCCCHHHHHHHHHHCC
TPTAGSVETRGRIAALLELGSGFNPEFTGRENIYMNGAVLGLTREEIDDRFDSIVSFADI
CCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCEEECCEEEECCHHHHHHHHHHHHHHHHH
GQFIDQPVKTYSSGMSVRLAFAVQAQVDPDILIVDEALSVGDVRFQAKCFARLQQLKDNG
HHHHHHHHHHHHCCCEEEEEEEEEECCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCC
TSVLLVTHSSEQIVTHCSSALLLNDGMQFEIGEPRHVVNRYLDLLFGKERRNPDSPQAQP
CEEEEEECCCHHHHHHHCCEEEECCCCEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCC
GDIFQEDKGYAESAYQLSTDSDVFQTRNGYNTHEYRWGDGTASILDFYLAANGEPYPSAI
CCCCCCCCCCCCCCEEECCCCHHHHCCCCCCCCCEEECCCHHHHHHHHHHCCCCCCCCEE
TVGQTVTLAVSIKFHSDMWRPILGITIKTKDGVTISGTNSEMADLLDLQALVKKGAILVG
EECCEEEEEEEEEECCCCCCCEEEEEEEECCCEEEECCCHHHHHHHHHHHHHHCCCEEEE
KCSFQCRLGPGDYFVSLGLATRENDEIIPHDRRYDSIHFIVEPHNKFHGLADLALDLSIS
EEEEEEEECCCCEEEEEEEEECCCCCCCCCCCCCCEEEEEECCCCHHCCHHHHHHHCCHH
HIVESNQI
HHHCCCCC
>Mature Secondary Structure
MFSEGENVAKATIPLALESAEKNLETSNENEKARRSSSDTAISVRGISKCYQIYDAPRDR
CCCCCCCCEEEEEEEEEHHHHHCCCCCCCCHHHHCCCCCCEEEEHHHHHHHHHHCCCHHH
LKQFIIPRLRLARQQSRQYFREFWALKGISFEVRKGETVGIIGRNGSGKSTLLQIICGTL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCEEEEEECCCCCHHHHHHHHHHCC
TPTAGSVETRGRIAALLELGSGFNPEFTGRENIYMNGAVLGLTREEIDDRFDSIVSFADI
CCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCEEECCEEEECCHHHHHHHHHHHHHHHHH
GQFIDQPVKTYSSGMSVRLAFAVQAQVDPDILIVDEALSVGDVRFQAKCFARLQQLKDNG
HHHHHHHHHHHHCCCEEEEEEEEEECCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCC
TSVLLVTHSSEQIVTHCSSALLLNDGMQFEIGEPRHVVNRYLDLLFGKERRNPDSPQAQP
CEEEEEECCCHHHHHHHCCEEEECCCCEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCC
GDIFQEDKGYAESAYQLSTDSDVFQTRNGYNTHEYRWGDGTASILDFYLAANGEPYPSAI
CCCCCCCCCCCCCCEEECCCCHHHHCCCCCCCCCEEECCCHHHHHHHHHHCCCCCCCCEE
TVGQTVTLAVSIKFHSDMWRPILGITIKTKDGVTISGTNSEMADLLDLQALVKKGAILVG
EECCEEEEEEEEEECCCCCCCEEEEEEEECCCEEEECCCHHHHHHHHHHHHHHCCCEEEE
KCSFQCRLGPGDYFVSLGLATRENDEIIPHDRRYDSIHFIVEPHNKFHGLADLALDLSIS
EEEEEEEECCCCEEEEEEEEECCCCCCCCCCCCCCEEEEEECCCCHHCCHHHHHHHCCHH
HIVESNQI
HHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; putrescine [Periplasm]; H2O [C]

Specific reaction: ATP + putrescine [Periplasm] + H2O = ADP + phosphate + putrescine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8491726 [H]