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The map label for this gene is trpS [H]

Identifier: 82703434

GI number: 82703434

Start: 2635068

End: 2636270

Strand: Direct

Name: trpS [H]

Synonym: Nmul_A2317

Alternate gene names: 82703434

Gene position: 2635068-2636270 (Clockwise)

Preceding gene: 82703433

Following gene: 82703435

Centisome position: 82.75

GC content: 55.53

Gene sequence:

>1203_bases
ATGTTCGCTGATCGTGTTTTGTCGGGAATGCGGCCGACGGGAGGCCTGCATCTGGGGCATTATCATGGGGTGCTCAAAAA
CTGGATAGAACTGCAACACCAGTTTGAGTGCCTGTTCTTTGTCGCCGACTGGCATGCCCTCACAACCCATTACGATACGC
CGGAAATCATCGAAGAGCATGTCTGGGACATGGTGATCGACTGGCTTGCAGCCGGTGTCGACCCGGCCCAGGCGACGTTG
TTCATACAGTCGCGTGTTCCCGCACACGCAGAGTTGCACGTGCTGCTTTCCATGATCACCCCGCTCGGCTGGCTGGAACG
TGTCCCGTCCTACAAGGATCAGCAGGAAAAGCTGGTTGAAAAAGAATTGAACACATATGGCTTCCTTGGATACCCCTTGC
TGCAAAGCGCGGACATCCTTATTTACCGGGCTACACGAGTGCCGGTGGGAGAGGATCAAACGCCGCATATCGAGTTCACC
CGGGAAATTGCGCGACGCTTTAATCATGTCTACGGCAAGGAGCCTGGATTCCAGGAAAAGGCGGAAGCGGCGATCAAGAA
ACTGGGGTCCCGAAAAGCCCGCCTCTATCGGGACTTGAGGAATCGCTATCAGGAACAGGGAGACGACGAAGCGCTTGCGG
CGGCGAAGTCATTGCTGGATGAGCAGCAAAATTTGAGCATGGGTGACCAGGAACGCTTGTTCGGGTATCTGGAAGGCGGT
GGAAAGATGATTCTTTCCGAGCCGGAAGCGATGCTGACGAAAGCGTCGAAAATGCCAGGGCTGGACGGGCAGAAGATGTC
CAAGTCTTATAACAACACCATTACCCTGCGTGAAGATCCGGAGAGCGTCACGAGAAAGATTCGTACGATGCCGACCGACC
CCGCCCGGGTGCGGCGTACCGACCCCGGAACCCCGGAGAAGTGCCCGGTATGGCAATTCCATCTCGTATACTCGGACGAA
GATACGAAGAGGTGGGCTTATGAGGGCTGTATCACTGCTGGTATCGGCTGTCTGGACTGCAAGCAGCCTGTCATCGATGC
AATACTGACCGAGCAGCGGCCAATGCATCAACGCGCGCGCATGTACGAAGAAGAGCCTTCACTGGTGCGAAATATCATTG
CTGACGGTTGCGAGAGGGCCGATAAGCTGGCACAGGAAACCATGCGTGAGGTGAGAGAGGCAATGGGACTGGATTATTCC
TGA

Upstream 100 bases:

>100_bases
CAATCACGATCCATTTGATGGCGTTGTTTTTTGGTTTCGCTACTTATTGAACTGCTTCTCTACATAAGGATTCTGATTGG
AGTTACCGAGGCAATGATCT

Downstream 100 bases:

>100_bases
TTTTTGCTTTGCGCGGGCACATGGGCAATGCAGCCGCATCGACGCGTGCTATCTGTCATAGACGTTGCTCGACTTACCCA
AGAATGAACGACTTTCAAAG

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MFADRVLSGMRPTGGLHLGHYHGVLKNWIELQHQFECLFFVADWHALTTHYDTPEIIEEHVWDMVIDWLAAGVDPAQATL
FIQSRVPAHAELHVLLSMITPLGWLERVPSYKDQQEKLVEKELNTYGFLGYPLLQSADILIYRATRVPVGEDQTPHIEFT
REIARRFNHVYGKEPGFQEKAEAAIKKLGSRKARLYRDLRNRYQEQGDDEALAAAKSLLDEQQNLSMGDQERLFGYLEGG
GKMILSEPEAMLTKASKMPGLDGQKMSKSYNNTITLREDPESVTRKIRTMPTDPARVRRTDPGTPEKCPVWQFHLVYSDE
DTKRWAYEGCITAGIGCLDCKQPVIDAILTEQRPMHQRARMYEEEPSLVRNIIADGCERADKLAQETMREVREAMGLDYS

Sequences:

>Translated_400_residues
MFADRVLSGMRPTGGLHLGHYHGVLKNWIELQHQFECLFFVADWHALTTHYDTPEIIEEHVWDMVIDWLAAGVDPAQATL
FIQSRVPAHAELHVLLSMITPLGWLERVPSYKDQQEKLVEKELNTYGFLGYPLLQSADILIYRATRVPVGEDQTPHIEFT
REIARRFNHVYGKEPGFQEKAEAAIKKLGSRKARLYRDLRNRYQEQGDDEALAAAKSLLDEQQNLSMGDQERLFGYLEGG
GKMILSEPEAMLTKASKMPGLDGQKMSKSYNNTITLREDPESVTRKIRTMPTDPARVRRTDPGTPEKCPVWQFHLVYSDE
DTKRWAYEGCITAGIGCLDCKQPVIDAILTEQRPMHQRARMYEEEPSLVRNIIADGCERADKLAQETMREVREAMGLDYS
>Mature_400_residues
MFADRVLSGMRPTGGLHLGHYHGVLKNWIELQHQFECLFFVADWHALTTHYDTPEIIEEHVWDMVIDWLAAGVDPAQATL
FIQSRVPAHAELHVLLSMITPLGWLERVPSYKDQQEKLVEKELNTYGFLGYPLLQSADILIYRATRVPVGEDQTPHIEFT
REIARRFNHVYGKEPGFQEKAEAAIKKLGSRKARLYRDLRNRYQEQGDDEALAAAKSLLDEQQNLSMGDQERLFGYLEGG
GKMILSEPEAMLTKASKMPGLDGQKMSKSYNNTITLREDPESVTRKIRTMPTDPARVRRTDPGTPEKCPVWQFHLVYSDE
DTKRWAYEGCITAGIGCLDCKQPVIDAILTEQRPMHQRARMYEEEPSLVRNIIADGCERADKLAQETMREVREAMGLDYS

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=398, Percent_Identity=26.8844221105528, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI41352700, Length=170, Percent_Identity=40.5882352941176, Blast_Score=137, Evalue=2e-32,
Organism=Escherichia coli, GI1789786, Length=398, Percent_Identity=28.643216080402, Blast_Score=162, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI71982800, Length=172, Percent_Identity=35.4651162790698, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI71982793, Length=172, Percent_Identity=35.4651162790698, Blast_Score=114, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6320474, Length=186, Percent_Identity=38.1720430107527, Blast_Score=131, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24666151, Length=398, Percent_Identity=25.6281407035176, Blast_Score=147, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 45781; Mature: 45781

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFADRVLSGMRPTGGLHLGHYHGVLKNWIELQHQFECLFFVADWHALTTHYDTPEIIEEH
CCHHHHHHCCCCCCCEECHHHHHHHHHHHHHHHHHHHEEEEEHHHHHHCCCCCHHHHHHH
VWDMVIDWLAAGVDPAQATLFIQSRVPAHAELHVLLSMITPLGWLERVPSYKDQQEKLVE
HHHHHHHHHHCCCCHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
KELNTYGFLGYPLLQSADILIYRATRVPVGEDQTPHIEFTREIARRFNHVYGKEPGFQEK
HHHHHCCCCCCHHHCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHH
AEAAIKKLGSRKARLYRDLRNRYQEQGDDEALAAAKSLLDEQQNLSMGDQERLFGYLEGG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCC
GKMILSEPEAMLTKASKMPGLDGQKMSKSYNNTITLREDPESVTRKIRTMPTDPARVRRT
CEEEECCCHHHHHHHHCCCCCCCHHHHHCCCCEEEEECCHHHHHHHHHCCCCCHHHCCCC
DPGTPEKCPVWQFHLVYSDEDTKRWAYEGCITAGIGCLDCKQPVIDAILTEQRPMHQRAR
CCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHH
MYEEEPSLVRNIIADGCERADKLAQETMREVREAMGLDYS
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MFADRVLSGMRPTGGLHLGHYHGVLKNWIELQHQFECLFFVADWHALTTHYDTPEIIEEH
CCHHHHHHCCCCCCCEECHHHHHHHHHHHHHHHHHHHEEEEEHHHHHHCCCCCHHHHHHH
VWDMVIDWLAAGVDPAQATLFIQSRVPAHAELHVLLSMITPLGWLERVPSYKDQQEKLVE
HHHHHHHHHHCCCCHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
KELNTYGFLGYPLLQSADILIYRATRVPVGEDQTPHIEFTREIARRFNHVYGKEPGFQEK
HHHHHCCCCCCHHHCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHH
AEAAIKKLGSRKARLYRDLRNRYQEQGDDEALAAAKSLLDEQQNLSMGDQERLFGYLEGG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCC
GKMILSEPEAMLTKASKMPGLDGQKMSKSYNNTITLREDPESVTRKIRTMPTDPARVRRT
CEEEECCCHHHHHHHHCCCCCCCHHHHHCCCCEEEEECCHHHHHHHHHCCCCCHHHCCCC
DPGTPEKCPVWQFHLVYSDEDTKRWAYEGCITAGIGCLDCKQPVIDAILTEQRPMHQRAR
CCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHH
MYEEEPSLVRNIIADGCERADKLAQETMREVREAMGLDYS
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]