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The map label for this gene is hcaT [H]

Identifier: 82703043

GI number: 82703043

Start: 2210900

End: 2212048

Strand: Reverse

Name: hcaT [H]

Synonym: Nmul_A1922

Alternate gene names: 82703043

Gene position: 2212048-2210900 (Counterclockwise)

Preceding gene: 82703044

Following gene: 82703042

Centisome position: 69.47

GC content: 54.4

Gene sequence:

>1149_bases
ATGCAATCCATCCCCTATTGGCGTCTTTCCGGCTTCTATTTCTTCCATTTTGCCTTTATTGGCGCCTTTGCTCCTTACTG
GACCCTTTACCTCAAATCCCTTTCTTTCGCTTCCTTTCAGATCGGGGTGCTCATGTCCCTGCTGCATGTCACTCGCATCT
TTGCCCCGGCTGCATGGGGCTGGCTTGCAGATCACGTCGGCAAGCGAATGTTCATTGTACGCTCGGCTGCAATTGCAGGC
TTGGTCAGCTACTGTGGCGTTTTTCTCGGCGAGTCCTATAGCTGGCTGTTTGTGGTCATGGCGCTGATGAGTTTTTTCTG
GAGCGCTTCCCTGCCGTTGATCGAGGCAACCACACTTTCATACCTGGGAGAAAACATCACAAAATACGGACTCATCCGGG
TGTGGGGTTCAGTAGGATTCATTCTGGCGGTAACCGGGGTTGGTTATCTGCTGGATGCGACCAGCATCAGCTCGCTGCTA
TGGGCTGTCCTTGGCTTCAAGCTCGGTATTGTCTTTTTTTCACGACTGATTCCTGAAGTCGGGACAGCAACGCATCCTGC
CACCGAGCATTCCATTCCACAAATATTCCGGCGGCCAGAAGTACTGGCCTTTTTTGCAGCGTGCCTGTTGATGGTGTTTG
CGCACGGCCCCTACTACACCTTTTATTCGATCTATCTTGTCGAGTACGGATACAGCAAAAGTCTCGTAGGCTGGCTGTGG
GCCACAGGGGTTATCTGTGAGATCGGCATATTTTTCCTGATGCCGCAGTTGATGCGCCGATTCCGCATGAAACAGATCAT
GGTGTTCAGTTTCAGCTGTGCCGTAGCACGCTTCCTGATGATAGGCTGGGGCGTGGAATGGCCGTTTGTCATATTTTCTG
CACAGGTGCTGCATGCCGCAACCTACGGGGCGCATCACGCCACCGCCATGATGGTGGTGCATCGGCTCTTCGGTGGGCGC
CACCAGGCGAAGGGGCAAGCCCTCTACACCAGTCTCACATTCGGGCTCGGCGGCACTATTGGGGGCATATTCAGCGGTTA
TTCGTGGGATTGGCTGGGGGCAGGACTCACTTTTACGATCAGTGCGATGGCCGTGTCGCTGGGCTTGGGGCTGGTAGTCT
GGAAGATGGACATCGACGGGTCCGCGTGA

Upstream 100 bases:

>100_bases
TTGACCTCCTCATGCGGCGAAGGCGGTCATCATGCTTTAAACCGCATATCCGTTACAGGCTGATTAAATGATCTGTCAAA
TAGCCTGTAAACTCGCATAA

Downstream 100 bases:

>100_bases
CAATTGCGTACTCTTGCTGTTCCTTGATATTTCATTATGGGATAATGAAACATTGAGATTTGAAGCCGTTATTCCCATTT
TCCACAAAAATGCAAACGTT

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MQSIPYWRLSGFYFFHFAFIGAFAPYWTLYLKSLSFASFQIGVLMSLLHVTRIFAPAAWGWLADHVGKRMFIVRSAAIAG
LVSYCGVFLGESYSWLFVVMALMSFFWSASLPLIEATTLSYLGENITKYGLIRVWGSVGFILAVTGVGYLLDATSISSLL
WAVLGFKLGIVFFSRLIPEVGTATHPATEHSIPQIFRRPEVLAFFAACLLMVFAHGPYYTFYSIYLVEYGYSKSLVGWLW
ATGVICEIGIFFLMPQLMRRFRMKQIMVFSFSCAVARFLMIGWGVEWPFVIFSAQVLHAATYGAHHATAMMVVHRLFGGR
HQAKGQALYTSLTFGLGGTIGGIFSGYSWDWLGAGLTFTISAMAVSLGLGLVVWKMDIDGSA

Sequences:

>Translated_382_residues
MQSIPYWRLSGFYFFHFAFIGAFAPYWTLYLKSLSFASFQIGVLMSLLHVTRIFAPAAWGWLADHVGKRMFIVRSAAIAG
LVSYCGVFLGESYSWLFVVMALMSFFWSASLPLIEATTLSYLGENITKYGLIRVWGSVGFILAVTGVGYLLDATSISSLL
WAVLGFKLGIVFFSRLIPEVGTATHPATEHSIPQIFRRPEVLAFFAACLLMVFAHGPYYTFYSIYLVEYGYSKSLVGWLW
ATGVICEIGIFFLMPQLMRRFRMKQIMVFSFSCAVARFLMIGWGVEWPFVIFSAQVLHAATYGAHHATAMMVVHRLFGGR
HQAKGQALYTSLTFGLGGTIGGIFSGYSWDWLGAGLTFTISAMAVSLGLGLVVWKMDIDGSA
>Mature_382_residues
MQSIPYWRLSGFYFFHFAFIGAFAPYWTLYLKSLSFASFQIGVLMSLLHVTRIFAPAAWGWLADHVGKRMFIVRSAAIAG
LVSYCGVFLGESYSWLFVVMALMSFFWSASLPLIEATTLSYLGENITKYGLIRVWGSVGFILAVTGVGYLLDATSISSLL
WAVLGFKLGIVFFSRLIPEVGTATHPATEHSIPQIFRRPEVLAFFAACLLMVFAHGPYYTFYSIYLVEYGYSKSLVGWLW
ATGVICEIGIFFLMPQLMRRFRMKQIMVFSFSCAVARFLMIGWGVEWPFVIFSAQVLHAATYGAHHATAMMVVHRLFGGR
HQAKGQALYTSLTFGLGGTIGGIFSGYSWDWLGAGLTFTISAMAVSLGLGLVVWKMDIDGSA

Specific function: Probable permease involved in the uptake of 3- phenylpropionic acid [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lacY/rafB permease family. HcaT subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788886, Length=368, Percent_Identity=27.9891304347826, Blast_Score=115, Evalue=4e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022814
- InterPro:   IPR016196
- InterPro:   IPR005276 [H]

Pfam domain/function: PF01306 LacY_symp [H]

EC number: NA

Molecular weight: Translated: 42475; Mature: 42475

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHCCEEEEEEEECCCCC
>Mature Secondary Structure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HHHHHHHCCEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9603882; 9205837; 9278503 [H]