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The map label for this gene is asd [H]

Identifier: 82703038

GI number: 82703038

Start: 2206306

End: 2207418

Strand: Reverse

Name: asd [H]

Synonym: Nmul_A1917

Alternate gene names: 82703038

Gene position: 2207418-2206306 (Counterclockwise)

Preceding gene: 82703039

Following gene: 82703036

Centisome position: 69.32

GC content: 56.06

Gene sequence:

>1113_bases
ATGAAACGAGTGGGTTTTATCGGTTGGCGTGGCATGGTAGGGTCGGTTCTCATGCAACGTATGCGGGAAGAAAATGATTT
TGCATTGGTCGAGCCAACTTTCTTTTCCACTTCGCAGAAGGGCGGCAAAGCACCGGACATCGGCCAGGAGGCTCCGCCGC
TGAAGGACGCGAATGATATAGGCGAGCTCAAGTCCATGGACATTCTGATTTCCTGTCAGGGAGGGGATTATACCGGCGCG
ATTTTTCCCCGGCTGCGGGAAGCAGGCTGGCAGGGTTACTGGATCGATGCAGCCTCCACGCTGCGGATGAAAGATGATGC
TGTCATCATACTGGACCCGGTCAACATGCCCGTTATCGAACAGGCTCTGCACGATGGGATAAAGAATTATATCGGAGGCA
ATTGCACCGTCAGCCTGATGCTGATGGCCATGAACGGGCTCTTCAAAGAAGAACTGGTGGAATGGATGAGCGCCATGACT
TATCAGGCAGCTTCCGGCGCCGGGGCGCAGAACATGCGGGAATTGCTTCTGCAAATGGGCGAAGCCCATCGCGTGGCGAA
AAATCTGCTGGATGACCCTGCGGCCGGAATACTCGACATCGACCGTGAAGTGGCGGGAACACTTCGTGATGAAAATTTTC
CAACCGAGAATTTCGGTGTGCCGCTTGCAGGCAGTCTCATCCCCTGGATAGACAGGGATTTGGGCAACGGGCAGACACGG
GAAGAGTGGAAGGGGCAATCCGAGACAAACAAAATACTGGGGCGTGGTGAACGAACGGTTCCCGTGGACGGTATCTGTGT
GCGTGTAGGGGCCATGCGTTGCCACAGCCAGGCGCTGACCGTGAAGCTGAAGAAGGATGTTCCGCTGGATGAGGTGGAAG
ACGTGCTTGCCGCTTCGAACAGTTGGGTAAGGGTCGTTCCCAATGAGCGGGAGCATACCTTGAAAGAGTTGACTCCCGCT
GCGGTTACCGGCAAGCTGACAATACCGGTTGGCCGGTTGCGCAAGCTTGCCATGGGCGGCGAGTATCTTTCTGCATTCAC
TGTGGGAGACCAGTTGCTTTGGGGGGCCGCAGAGCCGCTGCGCAGAATGCTCAGAATTCTGGTGGCGGCCTGA

Upstream 100 bases:

>100_bases
AACCGCAGCAATGGGTGATGCGGTTCTGGCAAGTTTGTAGCAACGACACTTCATATCCTGTGGTTGATCAACCACGATTT
CTTCCAAAAGAGAGATATCA

Downstream 100 bases:

>100_bases
GAATCGCTAGAAGCGGCAAAGGCGCGCGGTGAATCAAGACATCGTGCCGCCTGATTTCCATCTTCCGGAGCTTCCCCTGC
GCCTTTTCGAGAGTCATTTT

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 370; Mature: 370

Protein sequence:

>370_residues
MKRVGFIGWRGMVGSVLMQRMREENDFALVEPTFFSTSQKGGKAPDIGQEAPPLKDANDIGELKSMDILISCQGGDYTGA
IFPRLREAGWQGYWIDAASTLRMKDDAVIILDPVNMPVIEQALHDGIKNYIGGNCTVSLMLMAMNGLFKEELVEWMSAMT
YQAASGAGAQNMRELLLQMGEAHRVAKNLLDDPAAGILDIDREVAGTLRDENFPTENFGVPLAGSLIPWIDRDLGNGQTR
EEWKGQSETNKILGRGERTVPVDGICVRVGAMRCHSQALTVKLKKDVPLDEVEDVLAASNSWVRVVPNEREHTLKELTPA
AVTGKLTIPVGRLRKLAMGGEYLSAFTVGDQLLWGAAEPLRRMLRILVAA

Sequences:

>Translated_370_residues
MKRVGFIGWRGMVGSVLMQRMREENDFALVEPTFFSTSQKGGKAPDIGQEAPPLKDANDIGELKSMDILISCQGGDYTGA
IFPRLREAGWQGYWIDAASTLRMKDDAVIILDPVNMPVIEQALHDGIKNYIGGNCTVSLMLMAMNGLFKEELVEWMSAMT
YQAASGAGAQNMRELLLQMGEAHRVAKNLLDDPAAGILDIDREVAGTLRDENFPTENFGVPLAGSLIPWIDRDLGNGQTR
EEWKGQSETNKILGRGERTVPVDGICVRVGAMRCHSQALTVKLKKDVPLDEVEDVLAASNSWVRVVPNEREHTLKELTPA
AVTGKLTIPVGRLRKLAMGGEYLSAFTVGDQLLWGAAEPLRRMLRILVAA
>Mature_370_residues
MKRVGFIGWRGMVGSVLMQRMREENDFALVEPTFFSTSQKGGKAPDIGQEAPPLKDANDIGELKSMDILISCQGGDYTGA
IFPRLREAGWQGYWIDAASTLRMKDDAVIILDPVNMPVIEQALHDGIKNYIGGNCTVSLMLMAMNGLFKEELVEWMSAMT
YQAASGAGAQNMRELLLQMGEAHRVAKNLLDDPAAGILDIDREVAGTLRDENFPTENFGVPLAGSLIPWIDRDLGNGQTR
EEWKGQSETNKILGRGERTVPVDGICVRVGAMRCHSQALTVKLKKDVPLDEVEDVLAASNSWVRVVPNEREHTLKELTPA
AVTGKLTIPVGRLRKLAMGGEYLSAFTVGDQLLWGAAEPLRRMLRILVAA

Specific function: Second step in the common biosynthetic pathway leading from Asp to the cell wall precursor meso-diaminopimelate, to Lys, to Met, to Ile and to Thr. [C]

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789841, Length=367, Percent_Identity=66.7574931880109, Blast_Score=514, Evalue=1e-147,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR011534
- InterPro:   IPR012080
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 40591; Mature: 40591

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS01103 ASD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRVGFIGWRGMVGSVLMQRMREENDFALVEPTFFSTSQKGGKAPDIGQEAPPLKDANDI
CCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCEECCCCCCCCCCCCCCCCCCCCCCHHH
GELKSMDILISCQGGDYTGAIFPRLREAGWQGYWIDAASTLRMKDDAVIILDPVNMPVIE
HHHCCCEEEEEECCCCCCHHHHHHHHHCCCCEEEECCCCEEEECCCEEEEECCCCCHHHH
QALHDGIKNYIGGNCTVSLMLMAMNGLFKEELVEWMSAMTYQAASGAGAQNMRELLLQMG
HHHHHHHHHHCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
EAHRVAKNLLDDPAAGILDIDREVAGTLRDENFPTENFGVPLAGSLIPWIDRDLGNGQTR
HHHHHHHHHHCCCCCCCEECCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCH
EEWKGQSETNKILGRGERTVPVDGICVRVGAMRCHSQALTVKLKKDVPLDEVEDVLAASN
HHHCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHCCC
SWVRVVPNEREHTLKELTPAAVTGKLTIPVGRLRKLAMGGEYLSAFTVGDQLLWGAAEPL
CEEEECCCCHHHHHHHCCCHHCCCEEEECHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHH
RRMLRILVAA
HHHHHHHHCC
>Mature Secondary Structure
MKRVGFIGWRGMVGSVLMQRMREENDFALVEPTFFSTSQKGGKAPDIGQEAPPLKDANDI
CCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCEECCCCCCCCCCCCCCCCCCCCCCHHH
GELKSMDILISCQGGDYTGAIFPRLREAGWQGYWIDAASTLRMKDDAVIILDPVNMPVIE
HHHCCCEEEEEECCCCCCHHHHHHHHHCCCCEEEECCCCEEEECCCEEEEECCCCCHHHH
QALHDGIKNYIGGNCTVSLMLMAMNGLFKEELVEWMSAMTYQAASGAGAQNMRELLLQMG
HHHHHHHHHHCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
EAHRVAKNLLDDPAAGILDIDREVAGTLRDENFPTENFGVPLAGSLIPWIDRDLGNGQTR
HHHHHHHHHHCCCCCCCEECCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCH
EEWKGQSETNKILGRGERTVPVDGICVRVGAMRCHSQALTVKLKKDVPLDEVEDVLAASN
HHHCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHCCC
SWVRVVPNEREHTLKELTPAAVTGKLTIPVGRLRKLAMGGEYLSAFTVGDQLLWGAAEPL
CEEEECCCCHHHHHHHCCCHHCCCEEEECHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHH
RRMLRILVAA
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9084174; 10984043 [H]