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The map label for this gene is degP [H]

Identifier: 82702872

GI number: 82702872

Start: 2001686

End: 2003107

Strand: Direct

Name: degP [H]

Synonym: Nmul_A1749

Alternate gene names: 82702872

Gene position: 2001686-2003107 (Clockwise)

Preceding gene: 82702871

Following gene: 82702873

Centisome position: 62.86

GC content: 53.52

Gene sequence:

>1422_bases
ATGATTGCTAAATTTTTACTGGTGGTGCTGCTTGGATTATCCACGAGCGTGTTTGCCCAGGCGCCGGCGCGTGAATTGCC
GGATTTTACCGGGTTGGTGGAAAGAGAAGGACCCTCGGTCGTAAACATCAGCACCGTTCAGTCAGGCAACTCAACCACGG
AACGGGCTTTTCCGGGAATACCGAACATACCCGAGGATGATCCGTTTTTCGAGTTTTTCCGGAGACACATGCAGCCGCAT
GGAGGAATGCCACGAGATTTCGAATCCAGATCGGTAGGCTCCGGCTTTATTATCAGTTCGGATGGCTATATTCTGACAAA
TACCCATCTGGTGGATGGAGCCGATGAAATCAATGTGAAGCTTACGGACAAACGGGAGTTCCGGGCAAAGCTCATCGGCG
CGGATCGCAAGACGGATATTGCTCTCCTCAAGATCGATGCTACCGGACTGCCGAAAGTCACCCAGGGGGATCCCAATAAC
ATGAAGGTAGGAGAATGGGTGGTAGCGATCGGATCACCGTTCGGCTTTGAAAACAGCGTCACTGCCGGAATTGTCAGCGC
CAAAGGACGCTCTCTGGCACAGGAGAATTTCGTGCCCTTCATCCAGACGGATGTCGCGATCAACCCCGGGAATTCCGGCG
GACCGCTATTCAATATGAACGGTGAGGTGGTCGGTGTCAATTCCCAGATCTACAGTCGCACGGGTGGATTCATGGGTTTG
TCATTCGCCATTCCCATCGATGTTGCCCGGGATATATCGAATCAGTTGATTGCGAGCGGCAAGGTAAGCCGAGGCAGAAT
CGGCGTGCTGATTCAGGAAATCACAAAGGAACTGGCGGAATCGTTCGGTTTACCCAAGCCAGCCGGCGCGCTGGTAGCTT
CTGTCCAGAAAGGCGGCCCGGCAGACAAGGCAGGCATTCAAGCACGGGATGTCATTCTCAAGTTCGACGGCAAGACCGTG
AATTCCTCGGGCGATCTGCCACGCATAGTAGGCTCGACCAAGCCAGGCACGAAAGTGCAGATGCAGGTGTGGCGAAATGG
GTCGACCAAGGAGTTCACGATTACAGTGGATGAGCTTCCGGAGGATGAAAAACCGGCAGCGCGTTCTGGAAAGCGGGGCA
AGACGCCGGATACAGCGAATCGCATCGGCTTGAGCCTGATCGAGTTGACTCCCGATCAGAAGAAGGAACTGGAAACTGAA
AGCGGGCTTCTGGTCGAGGACATGGTGCCTGGTATCGCGAGTCGCGCGGGGGTCAGACCCGGTGATGTCATTCTGAGCAT
CAATAATCAGGATGTCAAAACGGTTGATCAATTCAACCAGTTGCTCAACAAGGTCGAGAAAGGACGCAATATCGCCCTGC
TGGTCAAACGCGGTGATACAGCCACCTTCATTACCATGAAGATGAATGGTGAACACAGATAA

Upstream 100 bases:

>100_bases
GCTCGGATTGAATGCAGTCCTGGTACCAGGTACTACTATTCCCTTATTTTGGGCAGATGGATGAAGGATTCACCCGTTTT
TACTCCATGGAAGAAAAAGT

Downstream 100 bases:

>100_bases
ATGACTGTCCCCGATCCTGATCTCCCTGTCTTGCTGACAGTCTATGGCCGGGAACACTGCCACCTCTGCCAGGACATGCT
CGCGGCCCTGCAGGAATTGA

Product: peptidase S1C, Do

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 473; Mature: 473

Protein sequence:

>473_residues
MIAKFLLVVLLGLSTSVFAQAPARELPDFTGLVEREGPSVVNISTVQSGNSTTERAFPGIPNIPEDDPFFEFFRRHMQPH
GGMPRDFESRSVGSGFIISSDGYILTNTHLVDGADEINVKLTDKREFRAKLIGADRKTDIALLKIDATGLPKVTQGDPNN
MKVGEWVVAIGSPFGFENSVTAGIVSAKGRSLAQENFVPFIQTDVAINPGNSGGPLFNMNGEVVGVNSQIYSRTGGFMGL
SFAIPIDVARDISNQLIASGKVSRGRIGVLIQEITKELAESFGLPKPAGALVASVQKGGPADKAGIQARDVILKFDGKTV
NSSGDLPRIVGSTKPGTKVQMQVWRNGSTKEFTITVDELPEDEKPAARSGKRGKTPDTANRIGLSLIELTPDQKKELETE
SGLLVEDMVPGIASRAGVRPGDVILSINNQDVKTVDQFNQLLNKVEKGRNIALLVKRGDTATFITMKMNGEHR

Sequences:

>Translated_473_residues
MIAKFLLVVLLGLSTSVFAQAPARELPDFTGLVEREGPSVVNISTVQSGNSTTERAFPGIPNIPEDDPFFEFFRRHMQPH
GGMPRDFESRSVGSGFIISSDGYILTNTHLVDGADEINVKLTDKREFRAKLIGADRKTDIALLKIDATGLPKVTQGDPNN
MKVGEWVVAIGSPFGFENSVTAGIVSAKGRSLAQENFVPFIQTDVAINPGNSGGPLFNMNGEVVGVNSQIYSRTGGFMGL
SFAIPIDVARDISNQLIASGKVSRGRIGVLIQEITKELAESFGLPKPAGALVASVQKGGPADKAGIQARDVILKFDGKTV
NSSGDLPRIVGSTKPGTKVQMQVWRNGSTKEFTITVDELPEDEKPAARSGKRGKTPDTANRIGLSLIELTPDQKKELETE
SGLLVEDMVPGIASRAGVRPGDVILSINNQDVKTVDQFNQLLNKVEKGRNIALLVKRGDTATFITMKMNGEHR
>Mature_473_residues
MIAKFLLVVLLGLSTSVFAQAPARELPDFTGLVEREGPSVVNISTVQSGNSTTERAFPGIPNIPEDDPFFEFFRRHMQPH
GGMPRDFESRSVGSGFIISSDGYILTNTHLVDGADEINVKLTDKREFRAKLIGADRKTDIALLKIDATGLPKVTQGDPNN
MKVGEWVVAIGSPFGFENSVTAGIVSAKGRSLAQENFVPFIQTDVAINPGNSGGPLFNMNGEVVGVNSQIYSRTGGFMGL
SFAIPIDVARDISNQLIASGKVSRGRIGVLIQEITKELAESFGLPKPAGALVASVQKGGPADKAGIQARDVILKFDGKTV
NSSGDLPRIVGSTKPGTKVQMQVWRNGSTKEFTITVDELPEDEKPAARSGKRGKTPDTANRIGLSLIELTPDQKKELETE
SGLLVEDMVPGIASRAGVRPGDVILSINNQDVKTVDQFNQLLNKVEKGRNIALLVKRGDTATFITMKMNGEHR

Specific function: Protease With A Shared Specificity With Degp. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=317, Percent_Identity=36.9085173501577, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI24308541, Length=256, Percent_Identity=35.15625, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI22129776, Length=304, Percent_Identity=34.8684210526316, Blast_Score=141, Evalue=2e-33,
Organism=Homo sapiens, GI7019477, Length=309, Percent_Identity=33.0097087378641, Blast_Score=135, Evalue=1e-31,
Organism=Escherichia coli, GI1789629, Length=452, Percent_Identity=36.5044247787611, Blast_Score=246, Evalue=2e-66,
Organism=Escherichia coli, GI1786356, Length=458, Percent_Identity=34.4978165938865, Blast_Score=240, Evalue=2e-64,
Organism=Escherichia coli, GI1789630, Length=321, Percent_Identity=36.1370716510903, Blast_Score=179, Evalue=4e-46,
Organism=Drosophila melanogaster, GI24646839, Length=274, Percent_Identity=33.5766423357664, Blast_Score=140, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.-

Molecular weight: Translated: 50808; Mature: 50808

Theoretical pI: Translated: 7.83; Mature: 7.83

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAKFLLVVLLGLSTSVFAQAPARELPDFTGLVEREGPSVVNISTVQSGNSTTERAFPGI
CHHHHHHHHHHHCCHHHHHCCCHHHCCCHHCHHCCCCCCEEEEEEECCCCCCHHHCCCCC
PNIPEDDPFFEFFRRHMQPHGGMPRDFESRSVGSGFIISSDGYILTNTHLVDGADEINVK
CCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCEEEEECEEECCCCEEEEE
LTDKREFRAKLIGADRKTDIALLKIDATGLPKVTQGDPNNMKVGEWVVAIGSPFGFENSV
EECCHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCC
TAGIVSAKGRSLAQENFVPFIQTDVAINPGNSGGPLFNMNGEVVGVNSQIYSRTGGFMGL
EEEEEECCCCHHHHHCCCCEEEECEEECCCCCCCCEEECCCCEEEECHHHHHCCCCCEEE
SFAIPIDVARDISNQLIASGKVSRGRIGVLIQEITKELAESFGLPKPAGALVASVQKGGP
EEEECHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCC
ADKAGIQARDVILKFDGKTVNSSGDLPRIVGSTKPGTKVQMQVWRNGSTKEFTITVDELP
CCCCCCEEEEEEEEECCEEECCCCCCCHHCCCCCCCCEEEEEEECCCCCEEEEEEHHCCC
EDEKPAARSGKRGKTPDTANRIGLSLIELTPDQKKELETESGLLVEDMVPGIASRAGVRP
CCCCCHHHCCCCCCCCCCHHHHCEEEEEECCCHHHHHHCCCCEEHHHHCCCHHHHCCCCC
GDVILSINNQDVKTVDQFNQLLNKVEKGRNIALLVKRGDTATFITMKMNGEHR
CCEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCEEEEEEEECCCCC
>Mature Secondary Structure
MIAKFLLVVLLGLSTSVFAQAPARELPDFTGLVEREGPSVVNISTVQSGNSTTERAFPGI
CHHHHHHHHHHHCCHHHHHCCCHHHCCCHHCHHCCCCCCEEEEEEECCCCCCHHHCCCCC
PNIPEDDPFFEFFRRHMQPHGGMPRDFESRSVGSGFIISSDGYILTNTHLVDGADEINVK
CCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCEEEEECEEECCCCEEEEE
LTDKREFRAKLIGADRKTDIALLKIDATGLPKVTQGDPNNMKVGEWVVAIGSPFGFENSV
EECCHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCC
TAGIVSAKGRSLAQENFVPFIQTDVAINPGNSGGPLFNMNGEVVGVNSQIYSRTGGFMGL
EEEEEECCCCHHHHHCCCCEEEECEEECCCCCCCCEEECCCCEEEECHHHHHCCCCCEEE
SFAIPIDVARDISNQLIASGKVSRGRIGVLIQEITKELAESFGLPKPAGALVASVQKGGP
EEEECHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCC
ADKAGIQARDVILKFDGKTVNSSGDLPRIVGSTKPGTKVQMQVWRNGSTKEFTITVDELP
CCCCCCEEEEEEEEECCEEECCCCCCCHHCCCCCCCCEEEEEEECCCCCEEEEEEHHCCC
EDEKPAARSGKRGKTPDTANRIGLSLIELTPDQKKELETESGLLVEDMVPGIASRAGVRP
CCCCCHHHCCCCCCCCCCHHHHCEEEEEECCCHHHHHHCCCCEEHHHHCCCHHHHCCCCC
GDVILSINNQDVKTVDQFNQLLNKVEKGRNIALLVKRGDTATFITMKMNGEHR
CCEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7861951 [H]