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The map label for this gene is hoxU [H]

Identifier: 82702795

GI number: 82702795

Start: 1910813

End: 1911550

Strand: Direct

Name: hoxU [H]

Synonym: Nmul_A1671

Alternate gene names: 82702795

Gene position: 1910813-1911550 (Clockwise)

Preceding gene: 82702794

Following gene: 82702796

Centisome position: 60.01

GC content: 56.37

Gene sequence:

>738_bases
ATGACCAGCACCATTACGATCGACGGAAAGACAGTGCCGTTCACCGAGGGGCAGACCATCATGGATGCGGCGCTCGCAGC
CAAGGTTTATATTCCCCACCTTTGCCATGATCCCGAGTTCAAACCCCACGGCAGCTGCAAGTTGTGTGTAGTGGAGGCCA
ATGGACGTAACGTCACATCCTGCACCATGCCTGCTTCCCCCGACATGGTGGTGATCAACGATACGCCCGAGCTGAATGAG
GATCGCAGGGCGCTGGTGCAGATGCTGTTCGTCGAAGGCAACCACATCTGCCCGGCTTGCGAAGCGACGGGAAATTGCCA
GTTGCAGGCGGCCGGCTACTACCTTCGCATGCAAAGCCCTCACTTCATGCACTTCTACCCCCCTCGCAGGGTGGATGCTT
CGCATCCCGACATTTTTCTCGATCTCAATCGCTGCATTCTGTGTGAGCTCTGCGTTCGCGCCAGCCGCGATATCGATAAA
AAGAACGTGTTCGGCATTTCAGGGCGAGGCATAGATTCTCATCTTGCGGTCAATTCCGAAAGCGGCAGATTGGGCGACAC
CGACATGGCGGTAACCGACAAGGCCGCGCATGTTTGCCCCACCGGCGCTATTCTGATCAAACGCAAAGGTTATACTGTAC
CCATAGGGCAGCGGATATTCGATCAGAAGACGCTGCGCGAATTCCATCTGGAGCAGCAGAAGCGAGTCGAGTCTGAGGAT
GGACCGGATGGCGGATGA

Upstream 100 bases:

>100_bases
AGCTCACCAGCCTGTCCTTCGAACCCGCATTCGATCTGGATGCCGCACTGGCGACAGCGCGCAGGATCACCGGCAGAGAC
GATCCATGGGCCCACTTGCC

Downstream 100 bases:

>100_bases
AAAACCCAAGATTCGCATCGCGACCTGTTCCCTGGCAGGATGTTTCGGCTGCCATACCTCACTGCTCGATATCGACGAGC
GGCTGTTTGATCTTATGGAG

Product: hydrogen dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 245; Mature: 244

Protein sequence:

>245_residues
MTSTITIDGKTVPFTEGQTIMDAALAAKVYIPHLCHDPEFKPHGSCKLCVVEANGRNVTSCTMPASPDMVVINDTPELNE
DRRALVQMLFVEGNHICPACEATGNCQLQAAGYYLRMQSPHFMHFYPPRRVDASHPDIFLDLNRCILCELCVRASRDIDK
KNVFGISGRGIDSHLAVNSESGRLGDTDMAVTDKAAHVCPTGAILIKRKGYTVPIGQRIFDQKTLREFHLEQQKRVESED
GPDGG

Sequences:

>Translated_245_residues
MTSTITIDGKTVPFTEGQTIMDAALAAKVYIPHLCHDPEFKPHGSCKLCVVEANGRNVTSCTMPASPDMVVINDTPELNE
DRRALVQMLFVEGNHICPACEATGNCQLQAAGYYLRMQSPHFMHFYPPRRVDASHPDIFLDLNRCILCELCVRASRDIDK
KNVFGISGRGIDSHLAVNSESGRLGDTDMAVTDKAAHVCPTGAILIKRKGYTVPIGQRIFDQKTLREFHLEQQKRVESED
GPDGG
>Mature_244_residues
TSTITIDGKTVPFTEGQTIMDAALAAKVYIPHLCHDPEFKPHGSCKLCVVEANGRNVTSCTMPASPDMVVINDTPELNED
RRALVQMLFVEGNHICPACEATGNCQLQAAGYYLRMQSPHFMHFYPPRRVDASHPDIFLDLNRCILCELCVRASRDIDKK
NVFGISGRGIDSHLAVNSESGRLGDTDMAVTDKAAHVCPTGAILIKRKGYTVPIGQRIFDQKTLREFHLEQQKRVESEDG
PDGG

Specific function: Subunits alpha and gamma of hoxS constitute an NADH-- oxidoreductase [H]

COG id: COG1034

COG function: function code C; NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI33519475, Length=210, Percent_Identity=23.3333333333333, Blast_Score=82, Evalue=5e-16,
Organism=Escherichia coli, GI145693161, Length=215, Percent_Identity=28.8372093023256, Blast_Score=90, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI193209088, Length=219, Percent_Identity=28.7671232876712, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI32566231, Length=219, Percent_Identity=28.7671232876712, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17565758, Length=219, Percent_Identity=28.7671232876712, Blast_Score=81, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24640559, Length=209, Percent_Identity=25.8373205741627, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24640557, Length=209, Percent_Identity=25.8373205741627, Blast_Score=76, Evalue=2e-14,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR016214
- InterPro:   IPR000283
- InterPro:   IPR019574 [H]

Pfam domain/function: PF00111 Fer2; PF10588 NADH-G_4Fe-4S_3 [H]

EC number: =1.12.1.2 [H]

Molecular weight: Translated: 27028; Mature: 26897

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
7.8 %Cys+Met (Translated Protein)
4.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
7.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSTITIDGKTVPFTEGQTIMDAALAAKVYIPHLCHDPEFKPHGSCKLCVVEANGRNVTS
CCCEEEECCCEECCCCCCHHHHHHHHHHHHCCHHCCCCCCCCCCCEEEEEEECCCCEEEE
CTMPASPDMVVINDTPELNEDRRALVQMLFVEGNHICPACEATGNCQLQAAGYYLRMQSP
EECCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCEEEEECCC
HFMHFYPPRRVDASHPDIFLDLNRCILCELCVRASRDIDKKNVFGISGRGIDSHLAVNSE
CEEEECCCCCCCCCCCCEEEECCHHHHHHHHHHHHCCCCCHHEEEECCCCCCCEEEEECC
SGRLGDTDMAVTDKAAHVCPTGAILIKRKGYTVPIGQRIFDQKTLREFHLEQQKRVESED
CCCCCCCCEEEECCCHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
GPDGG
CCCCC
>Mature Secondary Structure 
TSTITIDGKTVPFTEGQTIMDAALAAKVYIPHLCHDPEFKPHGSCKLCVVEANGRNVTS
CCEEEECCCEECCCCCCHHHHHHHHHHHHCCHHCCCCCCCCCCCEEEEEEECCCCEEEE
CTMPASPDMVVINDTPELNEDRRALVQMLFVEGNHICPACEATGNCQLQAAGYYLRMQSP
EECCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCEEEEECCC
HFMHFYPPRRVDASHPDIFLDLNRCILCELCVRASRDIDKKNVFGISGRGIDSHLAVNSE
CEEEECCCCCCCCCCCCEEEECCHHHHHHHHHHHHCCCCCHHEEEECCCCCCCEEEEECC
SGRLGDTDMAVTDKAAHVCPTGAILIKRKGYTVPIGQRIFDQKTLREFHLEQQKRVESED
CCCCCCCCEEEECCCHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
GPDGG
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2188945; 12948488; 2496982 [H]