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The map label for this gene is hoxF [H]

Identifier: 82702794

GI number: 82702794

Start: 1909020

End: 1910816

Strand: Direct

Name: hoxF [H]

Synonym: Nmul_A1670

Alternate gene names: 82702794

Gene position: 1909020-1910816 (Clockwise)

Preceding gene: 82702793

Following gene: 82702795

Centisome position: 59.95

GC content: 56.65

Gene sequence:

>1797_bases
ATGATGCAGCCCCCTGATCTTCCCGATATCGAACAGCAGATCGCAATCATATGCCAACGGCACGGCTGTGAGCCCCATCG
CCTGCTTCAGATCCTGATCGACGTGCAGGAGATGTACTGTTTTATTCCCCCTGAAGCCATCACCTTCATTGCCAGGCATC
TCAATCTCCCGCGGGTGAACGTGGAAGGCGCTGCCGGTTTCTATTCGTTTCTTTCGCTCGAACCCGCAGGCCGATACCGC
GTCCTGTTTTCCGACAACGTGACCGATCGGATGCTGGGTAACGAGGAACTAATGCGCCATTTCTGCAACAGGCTGTGGCT
TGAGCCTGGCAAAGTGTCGGAGGATGGACTGATCAGTACAAACTTTACTTCCTGTACCGGAATGTGCGACCAAGGACCGA
CCGCGCTGATCAATGGATGGCCGGTTACCCGCTTAAGCAAGGAGCGCATTGATCTCATCGCCGATTTGATCCTCAGCAAG
TCCCCTGTTTCTGACTGGCCGTCTACTTTGTTCGAGGTCAACGACAATATTCGCAGGACCGATCGGCTCCTGGGCGAACC
GTTCGAACCTGGCTCGGCGATCAGGGCAACACTCATGCGTGGCGCCGATGCGACACTGGGTGAACTCAAATTGTCCAGAT
TGAGAGGGCGCGGTGGAGCGGGATACGCAACGGCGGACAAGTGGACCGCTTGCCGGGATTCTGAGGGGACAGCGCGTTAT
ATCGTTTGCAACGCGGATGAAGGCGAGCCGGGGACATTCAAGGATCGTGTTTTGCTGAACCGTTACGCGGATATGGTGTT
TGAAGGCATGACCGTAGGCGCGCGACTGCTGGGTTCCACAAAGGGGTTTTTGTATCTGCGCGGGGAATACCAGTATCTCC
TAAAAAAACTTGAAGAGGTACTGGCACGGCGGTGCGAGGCTCGCCTGCTGGGCACCGATATCCTGGGCGAGCCAGGGTTC
GATTTCGATATCGAGATCCATCTGGGCGCCGGTGCGTATATATGTGGGGAAGAATCCGCGTTGATCGAATCGCTTGAAGG
GAGGCGAGGCAAGCCGCGCAACCGCCCGCCGTATCCTGCGCAGCATGGCTATCTCGATCAGCCCACAGTCGTGAACAACG
TGGAAACGTTTGCCTGTTCAGCCATGATCGCCGTGCATGGAGGCAAGTGGTTCGGGGAGACGGGTACATGGGAATCAAGT
GGCAGCAAGATTCTCAGCATCGCCGGCGACTGCACCTTGCCGGGCATTTACGAATATCCGTTCGGCGTGTCCGTGCGGGA
AATACTGCAAGATTGCGCTGCGGAAGAAGCCTATGCTGTTCAAGTCGGCGGTCCGTCCGGCATTCTTGTTTCCTGGAAGG
AATTCGAGCGCAGCATTTCGTTTGATGACTTGCCCACCGCGGGCGCCTTTACCATATTCGGGCGCGGCCGCGATATCTTG
GAGGCGGTGCGCAATTACGCCCACTTCTTCGCGCATGAAAGCTGCGGTTTCTGCACGCCCTGCCGGGTAGGAACGCAGTT
GCAGAAAAAGCTCGTGGATAAAATTGCAGACGGTCATGGCACGGCCTCGGATCTCGAAGAACTGAAGCATTTGGGACATC
TCATGAGAACCATGAGCCATTGCGGACTGGGACATACGGCTCCGAATCCGGTGCTGGATATGCTGGAAAAATTTCCCGGC
GCTTACGAGCAAAAGCTCACCAGCCTGTCCTTCGAACCCGCATTCGATCTGGATGCCGCACTGGCGACAGCGCGCAGGAT
CACCGGCAGAGACGATCCATGGGCCCACTTGCCATGA

Upstream 100 bases:

>100_bases
CCATGGCCGTCCGCACGTCGTACTTGAAACCGAACTGGGGGGAGAGCGTATTCTGGATGAACTGGAGGATGATCCGCTCC
CCCGGATATGCTAGAAATGA

Downstream 100 bases:

>100_bases
CCAGCACCATTACGATCGACGGAAAGACAGTGCCGTTCACCGAGGGGCAGACCATCATGGATGCGGCGCTCGCAGCCAAG
GTTTATATTCCCCACCTTTG

Product: hydrogen dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 598; Mature: 598

Protein sequence:

>598_residues
MMQPPDLPDIEQQIAIICQRHGCEPHRLLQILIDVQEMYCFIPPEAITFIARHLNLPRVNVEGAAGFYSFLSLEPAGRYR
VLFSDNVTDRMLGNEELMRHFCNRLWLEPGKVSEDGLISTNFTSCTGMCDQGPTALINGWPVTRLSKERIDLIADLILSK
SPVSDWPSTLFEVNDNIRRTDRLLGEPFEPGSAIRATLMRGADATLGELKLSRLRGRGGAGYATADKWTACRDSEGTARY
IVCNADEGEPGTFKDRVLLNRYADMVFEGMTVGARLLGSTKGFLYLRGEYQYLLKKLEEVLARRCEARLLGTDILGEPGF
DFDIEIHLGAGAYICGEESALIESLEGRRGKPRNRPPYPAQHGYLDQPTVVNNVETFACSAMIAVHGGKWFGETGTWESS
GSKILSIAGDCTLPGIYEYPFGVSVREILQDCAAEEAYAVQVGGPSGILVSWKEFERSISFDDLPTAGAFTIFGRGRDIL
EAVRNYAHFFAHESCGFCTPCRVGTQLQKKLVDKIADGHGTASDLEELKHLGHLMRTMSHCGLGHTAPNPVLDMLEKFPG
AYEQKLTSLSFEPAFDLDAALATARRITGRDDPWAHLP

Sequences:

>Translated_598_residues
MMQPPDLPDIEQQIAIICQRHGCEPHRLLQILIDVQEMYCFIPPEAITFIARHLNLPRVNVEGAAGFYSFLSLEPAGRYR
VLFSDNVTDRMLGNEELMRHFCNRLWLEPGKVSEDGLISTNFTSCTGMCDQGPTALINGWPVTRLSKERIDLIADLILSK
SPVSDWPSTLFEVNDNIRRTDRLLGEPFEPGSAIRATLMRGADATLGELKLSRLRGRGGAGYATADKWTACRDSEGTARY
IVCNADEGEPGTFKDRVLLNRYADMVFEGMTVGARLLGSTKGFLYLRGEYQYLLKKLEEVLARRCEARLLGTDILGEPGF
DFDIEIHLGAGAYICGEESALIESLEGRRGKPRNRPPYPAQHGYLDQPTVVNNVETFACSAMIAVHGGKWFGETGTWESS
GSKILSIAGDCTLPGIYEYPFGVSVREILQDCAAEEAYAVQVGGPSGILVSWKEFERSISFDDLPTAGAFTIFGRGRDIL
EAVRNYAHFFAHESCGFCTPCRVGTQLQKKLVDKIADGHGTASDLEELKHLGHLMRTMSHCGLGHTAPNPVLDMLEKFPG
AYEQKLTSLSFEPAFDLDAALATARRITGRDDPWAHLP
>Mature_598_residues
MMQPPDLPDIEQQIAIICQRHGCEPHRLLQILIDVQEMYCFIPPEAITFIARHLNLPRVNVEGAAGFYSFLSLEPAGRYR
VLFSDNVTDRMLGNEELMRHFCNRLWLEPGKVSEDGLISTNFTSCTGMCDQGPTALINGWPVTRLSKERIDLIADLILSK
SPVSDWPSTLFEVNDNIRRTDRLLGEPFEPGSAIRATLMRGADATLGELKLSRLRGRGGAGYATADKWTACRDSEGTARY
IVCNADEGEPGTFKDRVLLNRYADMVFEGMTVGARLLGSTKGFLYLRGEYQYLLKKLEEVLARRCEARLLGTDILGEPGF
DFDIEIHLGAGAYICGEESALIESLEGRRGKPRNRPPYPAQHGYLDQPTVVNNVETFACSAMIAVHGGKWFGETGTWESS
GSKILSIAGDCTLPGIYEYPFGVSVREILQDCAAEEAYAVQVGGPSGILVSWKEFERSISFDDLPTAGAFTIFGRGRDIL
EAVRNYAHFFAHESCGFCTPCRVGTQLQKKLVDKIADGHGTASDLEELKHLGHLMRTMSHCGLGHTAPNPVLDMLEKFPG
AYEQKLTSLSFEPAFDLDAALATARRITGRDDPWAHLP

Specific function: Subunits alpha and gamma of hoxS constitute an NADH-- oxidoreductase [H]

COG id: COG1894

COG function: function code C; NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 51 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI260656005, Length=386, Percent_Identity=37.8238341968912, Blast_Score=251, Evalue=2e-66,
Organism=Homo sapiens, GI20149568, Length=386, Percent_Identity=37.8238341968912, Blast_Score=251, Evalue=2e-66,
Organism=Escherichia coli, GI1788620, Length=374, Percent_Identity=37.7005347593583, Blast_Score=253, Evalue=2e-68,
Organism=Escherichia coli, GI1788621, Length=122, Percent_Identity=31.9672131147541, Blast_Score=69, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17531727, Length=389, Percent_Identity=35.73264781491, Blast_Score=240, Evalue=1e-63,
Organism=Drosophila melanogaster, GI19920794, Length=386, Percent_Identity=34.7150259067358, Blast_Score=241, Evalue=9e-64,
Organism=Drosophila melanogaster, GI45550452, Length=392, Percent_Identity=33.9285714285714, Blast_Score=236, Evalue=4e-62,
Organism=Drosophila melanogaster, GI24653819, Length=385, Percent_Identity=27.012987012987, Blast_Score=147, Evalue=3e-35,
Organism=Drosophila melanogaster, GI24653817, Length=347, Percent_Identity=25.9365994236311, Blast_Score=128, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001949
- InterPro:   IPR019575
- InterPro:   IPR002023
- InterPro:   IPR011538
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01257 Complex1_24kDa; PF01512 Complex1_51K; PF10589 NADH_4Fe-4S [H]

EC number: =1.12.1.2 [H]

Molecular weight: Translated: 66126; Mature: 66126

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: PS00644 COMPLEX1_51K_1 ; PS00645 COMPLEX1_51K_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMQPPDLPDIEQQIAIICQRHGCEPHRLLQILIDVQEMYCFIPPEAITFIARHLNLPRVN
CCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEECCHHHHHHHHHHCCCCCEE
VEGAAGFYSFLSLEPAGRYRVLFSDNVTDRMLGNEELMRHFCNRLWLEPGKVSEDGLIST
CCCCHHHHHHHEECCCCCEEEEEECCCHHHHCCCHHHHHHHHHHHCCCCCCCCCCCEEEC
NFTSCTGMCDQGPTALINGWPVTRLSKERIDLIADLILSKSPVSDWPSTLFEVNDNIRRT
CCCHHCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHH
DRLLGEPFEPGSAIRATLMRGADATLGELKLSRLRGRGGAGYATADKWTACRDSEGTARY
HHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEE
IVCNADEGEPGTFKDRVLLNRYADMVFEGMTVGARLLGSTKGFLYLRGEYQYLLKKLEEV
EEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHH
LARRCEARLLGTDILGEPGFDFDIEIHLGAGAYICGEESALIESLEGRRGKPRNRPPYPA
HHHHHHHHHHCHHHCCCCCCCEEEEEEECCCEEEECCHHHHHHHHHCCCCCCCCCCCCCC
QHGYLDQPTVVNNVETFACSAMIAVHGGKWFGETGTWESSGSKILSIAGDCTLPGIYEYP
CCCCCCCCCHHCCHHHHHHHEEEEEECCCEECCCCCCCCCCCEEEEEECCCCCCCCCCCC
FGVSVREILQDCAAEEAYAVQVGGPSGILVSWKEFERSISFDDLPTAGAFTIFGRGRDIL
CCCCHHHHHHHHCCCCEEEEEECCCCCEEEEHHHHHCCCCCCCCCCCCEEEEECCCHHHH
EAVRNYAHFFAHESCGFCTPCRVGTQLQKKLVDKIADGHGTASDLEELKHLGHLMRTMSH
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
CGLGHTAPNPVLDMLEKFPGAYEQKLTSLSFEPAFDLDAALATARRITGRDDPWAHLP
CCCCCCCCCHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MMQPPDLPDIEQQIAIICQRHGCEPHRLLQILIDVQEMYCFIPPEAITFIARHLNLPRVN
CCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEECCHHHHHHHHHHCCCCCEE
VEGAAGFYSFLSLEPAGRYRVLFSDNVTDRMLGNEELMRHFCNRLWLEPGKVSEDGLIST
CCCCHHHHHHHEECCCCCEEEEEECCCHHHHCCCHHHHHHHHHHHCCCCCCCCCCCEEEC
NFTSCTGMCDQGPTALINGWPVTRLSKERIDLIADLILSKSPVSDWPSTLFEVNDNIRRT
CCCHHCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHH
DRLLGEPFEPGSAIRATLMRGADATLGELKLSRLRGRGGAGYATADKWTACRDSEGTARY
HHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEE
IVCNADEGEPGTFKDRVLLNRYADMVFEGMTVGARLLGSTKGFLYLRGEYQYLLKKLEEV
EEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHH
LARRCEARLLGTDILGEPGFDFDIEIHLGAGAYICGEESALIESLEGRRGKPRNRPPYPA
HHHHHHHHHHCHHHCCCCCCCEEEEEEECCCEEEECCHHHHHHHHHCCCCCCCCCCCCCC
QHGYLDQPTVVNNVETFACSAMIAVHGGKWFGETGTWESSGSKILSIAGDCTLPGIYEYP
CCCCCCCCCHHCCHHHHHHHEEEEEECCCEECCCCCCCCCCCEEEEEECCCCCCCCCCCC
FGVSVREILQDCAAEEAYAVQVGGPSGILVSWKEFERSISFDDLPTAGAFTIFGRGRDIL
CCCCHHHHHHHHCCCCEEEEEECCCCCEEEEHHHHHCCCCCCCCCCCCEEEEECCCHHHH
EAVRNYAHFFAHESCGFCTPCRVGTQLQKKLVDKIADGHGTASDLEELKHLGHLMRTMSH
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
CGLGHTAPNPVLDMLEKFPGAYEQKLTSLSFEPAFDLDAALATARRITGRDDPWAHLP
CCCCCCCCCHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2188945; 12948488; 2496982 [H]