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The map label for this gene is arcB [H]

Identifier: 82702621

GI number: 82702621

Start: 1706112

End: 1707932

Strand: Direct

Name: arcB [H]

Synonym: Nmul_A1492

Alternate gene names: 82702621

Gene position: 1706112-1707932 (Clockwise)

Preceding gene: 82702620

Following gene: 82702622

Centisome position: 53.58

GC content: 48.82

Gene sequence:

>1821_bases
ATGTCAAAAAAGAATAATGAAGACGCTTTACTGCAATCGGTTGCTTTACAAACTGCCCAGACAATTTTGAGAGCCCGCCT
TCGGGCCGAGCGCGTTCTTGAGCAAGCAAAATTAGACTTGCAAGATAAGGCAAGACAACTGGATCATTCGCTCACCATTC
TTCGTGCTACAAGTACTGTGGAAAGGGAAAGATCGGAGTTAAGGAAAATGCCCGCGCCTCTATACCAGGAAGCATACAAG
CGGAAAGCGGAATGTCGGACGTGCGTTGTCGCTGAAAAAACTCCTCTAAAAATATTCACTGCGCGCATCGATGGCACCAA
GGATTACTTTAACGAAAGCTGGTTTGAATATACGGGGGTGGGCCTGGGGAAGTTGTTAGGCTGGGCATGGGTTGATCTTA
TTCACATCGAGGACATAGAAGAGAATTTAAAACGGTGGAAGCAATCCCTCCGGACCGGCGAGTCGTTCTGGATGGAAAAT
CGGATCAGACAGGCAACGGGCAACTATCGCTGGCATTCATCCTGCGCCACACCAATTCGTAATGCTGGCGGCGGGATCTG
GATGTGGGTGGGATATTGTATGGATATCCACGAAACAAAGATGAAAACCGAAGAACTGGGACGCTTTCTTGCAAAAGAGC
GGGAAATGCGTAAAGACGCAGAGCGTGTCAATCACTCCAAAGACGAGTTCTTCGCAATGCTGTCACATGAATTGAGGAAC
CCGCTCAATGCCATTCTCGGATGGTCCCAGCTTATTTTACAGGGAACAATGAATAGCGAGAGTGTTCGTAAAGGAATTGA
GACCATTGAGCGAAACGCCAAGATCCAAAATAAGCTCATCGAGGATCTTTTCGAAATGAGCAGGATCACTGCCGGGAAAG
TTACCTTGGAACTGCTGAGAATCGATCTCTCAAGTCTTACGGAAGCCGTTGTGGATTCGGCAGTACCGGTGGCGGAAGCA
AAAAAAGTTCGGCTGCGAAAAATAATCGATTCCGAGGTGGGATTTGTCCTGGCCGACGAAAATCGATTTCAGCAAGTCCT
GTGGAATTTACTGTCTAATGCCATAAAATTTACCCCCGCGGAAGGAGAAGTAGAAATCCATGTTCGGAGGGCAGGTTCTC
GCGCTGAAGTAAAGGTAAAGGATTCGGGAATCGGCATTAAACGAGAGTTTCTGCCACACGTTTTTGATCGCTTCCGCCAG
GCTGATTCCCCCGCCAGTCGGCAGCAGATCGGGCTCGGTCTGGGACTTGCCATTGTGAAGGAGCTAGTCTTGCTTCACAG
AGGCACCGTGATTGCCGAAAGCAATGGAGAAGGTAAAGGTTCAGTTTTTACTGTCAGCCTTCCTTTGATCCAGCATCGCG
ATACGGGAAGCGGAATCGAGAATCAAACCGATATTTTGTTAGAGTGCGACACACGTCTCCCGCTCACCGGCCTCACGCTT
CTGGTCATCGATGATGAAAGAGATTCTCTTGAAGTTGCGAAAGAGGCCCTTACAACGCAAGGTGGCACAGTAATTATTGC
GGGCGGTGCTGCAGAAGGCCTGGAAATTCTAAAAGCAAAGAGACCGGATGTGATAATTTGCGATATCAGTATGCCAGGCA
AAAATGGATATCAGTTCATCCGGGAAGTAAGAAGCATGCCAAAAACCACCCACTCATCTACACCGGCAATTGCGCTTACC
GGCTTTGCACGTCCCGAAGACCGGACAAAAGCGATGATTGCAGGCTACCAGAAACATATCATCAAGCCCCTGAACACGAC
CAAATTGGTTGCGGTCATTACAGACCTCGTGCCTCTCGTGCCAGACCAATCCCTCTCATAA

Upstream 100 bases:

>100_bases
CGTTCCATTCAATGTTCCACCCCCCCGAGGTTTGGGCCTGTAGCTTCATATAGGGATTCCCTGATTGTAGTGCGATCAGT
CTTTCCAGAAAGGATAGCCC

Downstream 100 bases:

>100_bases
TTCATCTCTTTATGGAAGCTCAATAAGTTTTTTTGCTTCCATATTAGATAAGAATTCTCCCCCTTATCACCCAGGCCCCA
AGGCTCAGGGACGTAATTCC

Product: PAS/PAC sensor hybrid histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 606; Mature: 605

Protein sequence:

>606_residues
MSKKNNEDALLQSVALQTAQTILRARLRAERVLEQAKLDLQDKARQLDHSLTILRATSTVERERSELRKMPAPLYQEAYK
RKAECRTCVVAEKTPLKIFTARIDGTKDYFNESWFEYTGVGLGKLLGWAWVDLIHIEDIEENLKRWKQSLRTGESFWMEN
RIRQATGNYRWHSSCATPIRNAGGGIWMWVGYCMDIHETKMKTEELGRFLAKEREMRKDAERVNHSKDEFFAMLSHELRN
PLNAILGWSQLILQGTMNSESVRKGIETIERNAKIQNKLIEDLFEMSRITAGKVTLELLRIDLSSLTEAVVDSAVPVAEA
KKVRLRKIIDSEVGFVLADENRFQQVLWNLLSNAIKFTPAEGEVEIHVRRAGSRAEVKVKDSGIGIKREFLPHVFDRFRQ
ADSPASRQQIGLGLGLAIVKELVLLHRGTVIAESNGEGKGSVFTVSLPLIQHRDTGSGIENQTDILLECDTRLPLTGLTL
LVIDDERDSLEVAKEALTTQGGTVIIAGGAAEGLEILKAKRPDVIICDISMPGKNGYQFIREVRSMPKTTHSSTPAIALT
GFARPEDRTKAMIAGYQKHIIKPLNTTKLVAVITDLVPLVPDQSLS

Sequences:

>Translated_606_residues
MSKKNNEDALLQSVALQTAQTILRARLRAERVLEQAKLDLQDKARQLDHSLTILRATSTVERERSELRKMPAPLYQEAYK
RKAECRTCVVAEKTPLKIFTARIDGTKDYFNESWFEYTGVGLGKLLGWAWVDLIHIEDIEENLKRWKQSLRTGESFWMEN
RIRQATGNYRWHSSCATPIRNAGGGIWMWVGYCMDIHETKMKTEELGRFLAKEREMRKDAERVNHSKDEFFAMLSHELRN
PLNAILGWSQLILQGTMNSESVRKGIETIERNAKIQNKLIEDLFEMSRITAGKVTLELLRIDLSSLTEAVVDSAVPVAEA
KKVRLRKIIDSEVGFVLADENRFQQVLWNLLSNAIKFTPAEGEVEIHVRRAGSRAEVKVKDSGIGIKREFLPHVFDRFRQ
ADSPASRQQIGLGLGLAIVKELVLLHRGTVIAESNGEGKGSVFTVSLPLIQHRDTGSGIENQTDILLECDTRLPLTGLTL
LVIDDERDSLEVAKEALTTQGGTVIIAGGAAEGLEILKAKRPDVIICDISMPGKNGYQFIREVRSMPKTTHSSTPAIALT
GFARPEDRTKAMIAGYQKHIIKPLNTTKLVAVITDLVPLVPDQSLS
>Mature_605_residues
SKKNNEDALLQSVALQTAQTILRARLRAERVLEQAKLDLQDKARQLDHSLTILRATSTVERERSELRKMPAPLYQEAYKR
KAECRTCVVAEKTPLKIFTARIDGTKDYFNESWFEYTGVGLGKLLGWAWVDLIHIEDIEENLKRWKQSLRTGESFWMENR
IRQATGNYRWHSSCATPIRNAGGGIWMWVGYCMDIHETKMKTEELGRFLAKEREMRKDAERVNHSKDEFFAMLSHELRNP
LNAILGWSQLILQGTMNSESVRKGIETIERNAKIQNKLIEDLFEMSRITAGKVTLELLRIDLSSLTEAVVDSAVPVAEAK
KVRLRKIIDSEVGFVLADENRFQQVLWNLLSNAIKFTPAEGEVEIHVRRAGSRAEVKVKDSGIGIKREFLPHVFDRFRQA
DSPASRQQIGLGLGLAIVKELVLLHRGTVIAESNGEGKGSVFTVSLPLIQHRDTGSGIENQTDILLECDTRLPLTGLTLL
VIDDERDSLEVAKEALTTQGGTVIIAGGAAEGLEILKAKRPDVIICDISMPGKNGYQFIREVRSMPKTTHSSTPAIALTG
FARPEDRTKAMIAGYQKHIIKPLNTTKLVAVITDLVPLVPDQSLS

Specific function: Member of the two-component regulatory system ArcB/ArcA. Sensor-regulator protein for anaerobic repression of the arc modulon. Activates ArcA via a four-step phosphorelay. ArcB can also dephosphorylate ArcA by a reverse phosphorelay involving His- 717 and

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=394, Percent_Identity=29.9492385786802, Blast_Score=156, Evalue=3e-39,
Organism=Escherichia coli, GI1788713, Length=439, Percent_Identity=28.7015945330296, Blast_Score=151, Evalue=1e-37,
Organism=Escherichia coli, GI87081816, Length=371, Percent_Identity=29.3800539083558, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1789149, Length=367, Percent_Identity=30.7901907356948, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI145693157, Length=237, Percent_Identity=34.1772151898734, Blast_Score=125, Evalue=8e-30,
Organism=Escherichia coli, GI1786600, Length=223, Percent_Identity=30.0448430493274, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1786783, Length=276, Percent_Identity=26.8115942028986, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1786912, Length=243, Percent_Identity=30.8641975308642, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1790436, Length=218, Percent_Identity=29.3577981651376, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1788393, Length=251, Percent_Identity=26.2948207171315, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1788279, Length=246, Percent_Identity=29.2682926829268, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1788549, Length=246, Percent_Identity=29.2682926829268, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1790861, Length=271, Percent_Identity=29.520295202952, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI1787894, Length=224, Percent_Identity=29.4642857142857, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1790346, Length=231, Percent_Identity=30.3030303030303, Blast_Score=76, Evalue=8e-15,
Organism=Escherichia coli, GI87082128, Length=227, Percent_Identity=26.8722466960352, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1787487, Length=111, Percent_Identity=27.9279279279279, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR014409
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 68068; Mature: 67937

Theoretical pI: Translated: 8.74; Mature: 8.74

Prosite motif: PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKKNNEDALLQSVALQTAQTILRARLRAERVLEQAKLDLQDKARQLDHSLTILRATSTV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHEEEEEHHHHH
ERERSELRKMPAPLYQEAYKRKAECRTCVVAEKTPLKIFTARIDGTKDYFNESWFEYTGV
HHHHHHHHHCCCHHHHHHHHHHHHHHEEEEECCCCEEEEEEEECCCHHHHCCCHHHHHCC
GLGKLLGWAWVDLIHIEDIEENLKRWKQSLRTGESFWMENRIRQATGNYRWHSSCATPIR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEECCCCCCCHH
NAGGGIWMWVGYCMDIHETKMKTEELGRFLAKEREMRKDAERVNHSKDEFFAMLSHELRN
HCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
PLNAILGWSQLILQGTMNSESVRKGIETIERNAKIQNKLIEDLFEMSRITAGKVTLELLR
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IDLSSLTEAVVDSAVPVAEAKKVRLRKIIDSEVGFVLADENRFQQVLWNLLSNAIKFTPA
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHEEECCC
EGEVEIHVRRAGSRAEVKVKDSGIGIKREFLPHVFDRFRQADSPASRQQIGLGLGLAIVK
CCCEEEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHCCCHHHHHHH
ELVLLHRGTVIAESNGEGKGSVFTVSLPLIQHRDTGSGIENQTDILLECDTRLPLTGLTL
HHHHHHCCCEEEECCCCCCCCEEEEEECCEEECCCCCCCCCCCCEEEEECCCCCCCCEEE
LVIDDERDSLEVAKEALTTQGGTVIIAGGAAEGLEILKAKRPDVIICDISMPGKNGYQFI
EEEECCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHCCCCCEEEEEECCCCCCHHHHH
REVRSMPKTTHSSTPAIALTGFARPEDRTKAMIAGYQKHIIKPLNTTKLVAVITDLVPLV
HHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCC
PDQSLS
CCCCCC
>Mature Secondary Structure 
SKKNNEDALLQSVALQTAQTILRARLRAERVLEQAKLDLQDKARQLDHSLTILRATSTV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHEEEEEHHHHH
ERERSELRKMPAPLYQEAYKRKAECRTCVVAEKTPLKIFTARIDGTKDYFNESWFEYTGV
HHHHHHHHHCCCHHHHHHHHHHHHHHEEEEECCCCEEEEEEEECCCHHHHCCCHHHHHCC
GLGKLLGWAWVDLIHIEDIEENLKRWKQSLRTGESFWMENRIRQATGNYRWHSSCATPIR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEECCCCCCCHH
NAGGGIWMWVGYCMDIHETKMKTEELGRFLAKEREMRKDAERVNHSKDEFFAMLSHELRN
HCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
PLNAILGWSQLILQGTMNSESVRKGIETIERNAKIQNKLIEDLFEMSRITAGKVTLELLR
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IDLSSLTEAVVDSAVPVAEAKKVRLRKIIDSEVGFVLADENRFQQVLWNLLSNAIKFTPA
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHEEECCC
EGEVEIHVRRAGSRAEVKVKDSGIGIKREFLPHVFDRFRQADSPASRQQIGLGLGLAIVK
CCCEEEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHCCCHHHHHHH
ELVLLHRGTVIAESNGEGKGSVFTVSLPLIQHRDTGSGIENQTDILLECDTRLPLTGLTL
HHHHHHCCCEEEECCCCCCCCEEEEEECCEEECCCCCCCCCCCCEEEEECCCCCCCCEEE
LVIDDERDSLEVAKEALTTQGGTVIIAGGAAEGLEILKAKRPDVIICDISMPGKNGYQFI
EEEECCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHCCCCCEEEEEECCCCCCHHHHH
REVRSMPKTTHSSTPAIALTGFARPEDRTKAMIAGYQKHIIKPLNTTKLVAVITDLVPLV
HHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCC
PDQSLS
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]