Click here to switch to the map view.

The map label for this gene is prtE [H]

Identifier: 82702410

GI number: 82702410

Start: 1473568

End: 1474932

Strand: Direct

Name: prtE [H]

Synonym: Nmul_A1281

Alternate gene names: 82702410

Gene position: 1473568-1474932 (Clockwise)

Preceding gene: 82702409

Following gene: 82702411

Centisome position: 46.28

GC content: 56.04

Gene sequence:

>1365_bases
ATGGCGGCGAGGTTGCAGGAAGACAGCGTTGTCGGCACTTATGAAGGGCACCATGGGCGCAAGCACGCTTTTCCGGGAAT
AGACGGAGATGCGACCTGGTATACGCGCCTCGGCTGGTGGATAGTGGTGGGAGGGGTCGGCGGGTTTCTGCTGTGGGCTT
CCCTGGCGCCGCTGGACAAAGGGGTGCCGCTCAGCGGGACGGTGATGGTGGCGACCAACAGGAAAGCGGTCCAGCATCAA
ACCGGAGGAACGATCGAAGATATCCCTGTGAAAGAAGGGGATGTAGTCAAGGCCGGCACCGTGCTGGTGCGCATGAACAG
CGTGCAGGTCAAGGCGAATGCCGAAACGATGCGTGTGCAGTATTTTGCCGCGCGCGCAGCCGAGGCGCGTTTGATTGCCG
AGCGCGATGGAAAGAAAGAGATCGTTTTCCCCCGGGAATTGGAGAACATGAAAAGTGATCCCATCGTTGCCACTTATATC
GACATGCAGAAGCAATTATTCAGTTCGCGTTTACTGGGTATCCAGAGTGAATTGTCGGGGATCGACGAGAGTATTTCCGG
CTTGAAGCTGCAAACCAGCGGGCTGGAGGAATCGCGAGACAACAAGAAACAGCAGCTGAAATTTCTGGGAGAGCAGCTGG
AGGGGATGCGCGATCTGGCCGCGGAAGGTTACGTGGCGCGCAATCGCTTGCTGGAACTGGAGCGCACCTACGCGCAGATA
AATGGCTCCATCTCCGAAGATATCGGCAATATCGGACGGGCGCGGCGGCAGATCGTGGAATTGAAGCTGCGCCGGGTGCA
GCGTCAGCAGGAATATCAGAAGGAAGTGCGATCGGAACTCACGGAGGTGCAGAAAGAAGCGGAAGCGCTTGCCCATAAAT
TGAGCGGGCTGGATTATGAGCTGGCGAATGTGCTGGTCAAGGCCCCAGTGGATGGAACCGTAGTGGGGCTGAATGTTTTC
ACGCGGGGAGGCGTAGTGAGTCCGGGCTTCAAGATGATGGACATTGTACCGAGCGACGACCCCTTGACGGTGGAAGGGCA
CCTGCCGGTGCATCTGATCGATAAAGTTCACCCTGATCTTCCGGTAGAGTTTATATTTACCGCATTCAACCGCAATCTGA
CGCCCCACGTGCCCGGAATCGTGACCCATGTTTCCGCAGATCGTCTTGTGGATGAAGATAGCGGGGAGCCTTACTACAAG
CTGCAGGCCAAGGTGGCACCGGAAGGGATGAAAATGATTGCGGATTTGCAGATCAGGCCAGGCATGCCGGTTGAACTCTT
CGTAAAGACGGGCGAACGCACCATGATGAATTACATTCTCAAGCCGATTCTGGATCATTTCAAAATGGCGATGACAGAGG
AGTAG

Upstream 100 bases:

>100_bases
TGATCAAGGTGCAGGTCCAGGGAGAAGAAAGAACAGGATAGCCAGACGGGACAGTCCTGTTCTGCCTGGAGAGCGTGAAG
CCACAAAGGAGTGAATTGAA

Downstream 100 bases:

>100_bases
GGTGCCAGCATGACACCCGCCGCGCGCGTTCTGATTGCTGCCGCCATAGGGCTGGGGAGCATGCTTCATGCGGGCCACGC
ATCCGCACTGGGGCTGATGG

Product: Type I secretion membrane fusion protein HlyD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 454; Mature: 453

Protein sequence:

>454_residues
MAARLQEDSVVGTYEGHHGRKHAFPGIDGDATWYTRLGWWIVVGGVGGFLLWASLAPLDKGVPLSGTVMVATNRKAVQHQ
TGGTIEDIPVKEGDVVKAGTVLVRMNSVQVKANAETMRVQYFAARAAEARLIAERDGKKEIVFPRELENMKSDPIVATYI
DMQKQLFSSRLLGIQSELSGIDESISGLKLQTSGLEESRDNKKQQLKFLGEQLEGMRDLAAEGYVARNRLLELERTYAQI
NGSISEDIGNIGRARRQIVELKLRRVQRQQEYQKEVRSELTEVQKEAEALAHKLSGLDYELANVLVKAPVDGTVVGLNVF
TRGGVVSPGFKMMDIVPSDDPLTVEGHLPVHLIDKVHPDLPVEFIFTAFNRNLTPHVPGIVTHVSADRLVDEDSGEPYYK
LQAKVAPEGMKMIADLQIRPGMPVELFVKTGERTMMNYILKPILDHFKMAMTEE

Sequences:

>Translated_454_residues
MAARLQEDSVVGTYEGHHGRKHAFPGIDGDATWYTRLGWWIVVGGVGGFLLWASLAPLDKGVPLSGTVMVATNRKAVQHQ
TGGTIEDIPVKEGDVVKAGTVLVRMNSVQVKANAETMRVQYFAARAAEARLIAERDGKKEIVFPRELENMKSDPIVATYI
DMQKQLFSSRLLGIQSELSGIDESISGLKLQTSGLEESRDNKKQQLKFLGEQLEGMRDLAAEGYVARNRLLELERTYAQI
NGSISEDIGNIGRARRQIVELKLRRVQRQQEYQKEVRSELTEVQKEAEALAHKLSGLDYELANVLVKAPVDGTVVGLNVF
TRGGVVSPGFKMMDIVPSDDPLTVEGHLPVHLIDKVHPDLPVEFIFTAFNRNLTPHVPGIVTHVSADRLVDEDSGEPYYK
LQAKVAPEGMKMIADLQIRPGMPVELFVKTGERTMMNYILKPILDHFKMAMTEE
>Mature_453_residues
AARLQEDSVVGTYEGHHGRKHAFPGIDGDATWYTRLGWWIVVGGVGGFLLWASLAPLDKGVPLSGTVMVATNRKAVQHQT
GGTIEDIPVKEGDVVKAGTVLVRMNSVQVKANAETMRVQYFAARAAEARLIAERDGKKEIVFPRELENMKSDPIVATYID
MQKQLFSSRLLGIQSELSGIDESISGLKLQTSGLEESRDNKKQQLKFLGEQLEGMRDLAAEGYVARNRLLELERTYAQIN
GSISEDIGNIGRARRQIVELKLRRVQRQQEYQKEVRSELTEVQKEAEALAHKLSGLDYELANVLVKAPVDGTVVGLNVFT
RGGVVSPGFKMMDIVPSDDPLTVEGHLPVHLIDKVHPDLPVEFIFTAFNRNLTPHVPGIVTHVSADRLVDEDSGEPYYKL
QAKVAPEGMKMIADLQIRPGMPVELFVKTGERTMMNYILKPILDHFKMAMTEE

Specific function: Involved in the secretion of proteases A, B, C and G [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR010129 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 50436; Mature: 50305

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAARLQEDSVVGTYEGHHGRKHAFPGIDGDATWYTRLGWWIVVGGVGGFLLWASLAPLDK
CCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCEEEECCEEEEECCHHHHHHHHHHCCCCC
GVPLSGTVMVATNRKAVQHQTGGTIEDIPVKEGDVVKAGTVLVRMNSVQVKANAETMRVQ
CCCCCCEEEEEECCHHHHHCCCCCEEECCCCCCCEEEECEEEEEEEEEEEEECCCCEEEH
YFAARAAEARLIAERDGKKEIVFPRELENMKSDPIVATYIDMQKQLFSSRLLGIQSELSG
HHHHHHHHHHHHHCCCCCCCEECCHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHH
IDESISGLKLQTSGLEESRDNKKQQLKFLGEQLEGMRDLAAEGYVARNRLLELERTYAQI
HHHHHCCCEEEECCCCHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
NGSISEDIGNIGRARRQIVELKLRRVQRQQEYQKEVRSELTEVQKEAEALAHKLSGLDYE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
LANVLVKAPVDGTVVGLNVFTRGGVVSPGFKMMDIVPSDDPLTVEGHLPVHLIDKVHPDL
HHHEEEECCCCCEEEEEEEEECCCCCCCCCEEEEEECCCCCEEEECCCCEEEHHHCCCCC
PVEFIFTAFNRNLTPHVPGIVTHVSADRLVDEDSGEPYYKLQAKVAPEGMKMIADLQIRP
CHHHHHHHHCCCCCCCCCCCEEECCHHHHCCCCCCCCEEEEEEEECCCHHHHHEEEEECC
GMPVELFVKTGERTMMNYILKPILDHFKMAMTEE
CCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AARLQEDSVVGTYEGHHGRKHAFPGIDGDATWYTRLGWWIVVGGVGGFLLWASLAPLDK
CCCCCCCCEEEEECCCCCCCCCCCCCCCCCCEEEECCEEEEECCHHHHHHHHHHCCCCC
GVPLSGTVMVATNRKAVQHQTGGTIEDIPVKEGDVVKAGTVLVRMNSVQVKANAETMRVQ
CCCCCCEEEEEECCHHHHHCCCCCEEECCCCCCCEEEECEEEEEEEEEEEEECCCCEEEH
YFAARAAEARLIAERDGKKEIVFPRELENMKSDPIVATYIDMQKQLFSSRLLGIQSELSG
HHHHHHHHHHHHHCCCCCCCEECCHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHH
IDESISGLKLQTSGLEESRDNKKQQLKFLGEQLEGMRDLAAEGYVARNRLLELERTYAQI
HHHHHCCCEEEECCCCHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
NGSISEDIGNIGRARRQIVELKLRRVQRQQEYQKEVRSELTEVQKEAEALAHKLSGLDYE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
LANVLVKAPVDGTVVGLNVFTRGGVVSPGFKMMDIVPSDDPLTVEGHLPVHLIDKVHPDL
HHHEEEECCCCCEEEEEEEEECCCCCCCCCEEEEEECCCCCEEEECCCCEEEHHHCCCCC
PVEFIFTAFNRNLTPHVPGIVTHVSADRLVDEDSGEPYYKLQAKVAPEGMKMIADLQIRP
CHHHHHHHHCCCCCCCCCCCEEECCHHHHCCCCCCCCEEEEEEEECCCHHHHHEEEEECC
GMPVELFVKTGERTMMNYILKPILDHFKMAMTEE
CCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2184029 [H]