Click here to switch to the map view.

The map label for this gene is uvrY [H]

Identifier: 82702364

GI number: 82702364

Start: 1419342

End: 1419977

Strand: Reverse

Name: uvrY [H]

Synonym: Nmul_A1235

Alternate gene names: 82702364

Gene position: 1419977-1419342 (Counterclockwise)

Preceding gene: 82702365

Following gene: 82702361

Centisome position: 44.59

GC content: 52.67

Gene sequence:

>636_bases
TTGATCATCAAGACCTTTCTGGCTGACGATCATCGGCTTTTTCGTGATGGTTTGCGACGCATTCTTGCCGAAACAACAGA
TATCGTAGTCGTAGGCGAGGCTACGGATGGACTCGATGCTTTGAAAAAAATGCGCCTCGGGGGATGGGATGTGGGGTTGC
TTGACGTCAGCATGCCTGGAATGAACGGGCTCGAGGTGCTACAACGGATCATGGACGACGATCCAAAGCATCGCATACTG
ATGCTCAGCACCTACCATGAAGACGAGTATGCCATTCGTGCGATACGCGCCGGTACTTCAGCCTATCTGACAAAAAATAG
CCCGACTGACCTGTTGATATCGGTAATTCGCCGACTGGCGCATGGGGGAAGATACATAGATCCGAAACTGGCCGAGAAAC
TTCTGTTCGACCTGGGTCCCTCTTCCACCATGCCACGCCACTCCGCCCTTTCCAACCGCGAACTCGATGTTCTCAAGCTC
ATCGCAGTCGGAATATCCCTGACCGAAATCTCCCAGAAGCTGAAACTGAGTGCGAAAACGATCAGTACCTATCGTGCGCG
CGTCCTCGAAAAAATGGGCATGCAGAACAACGCGCAACTGATCCGCTACGTGGCGGAGCATAAGCTGCTCGAATAG

Upstream 100 bases:

>100_bases
TCCATTGTTGCGGAGTACCGCGCGCTGCCCGTATCTTCACAAAATAATGGAATATCCGTTTCATGAGCATCGCTGAGTAC
CCGTTTTCAGGAGAGCGTGC

Downstream 100 bases:

>100_bases
GAATTCATGCAGATCGATCCCACTTCGTGCAGCGGCCGGATGCGATTCCCGGAATCTCTTCGGCCTGTCCTGGTTTACTA
TCCGCAGCAACTCGGCTCTT

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MIIKTFLADDHRLFRDGLRRILAETTDIVVVGEATDGLDALKKMRLGGWDVGLLDVSMPGMNGLEVLQRIMDDDPKHRIL
MLSTYHEDEYAIRAIRAGTSAYLTKNSPTDLLISVIRRLAHGGRYIDPKLAEKLLFDLGPSSTMPRHSALSNRELDVLKL
IAVGISLTEISQKLKLSAKTISTYRARVLEKMGMQNNAQLIRYVAEHKLLE

Sequences:

>Translated_211_residues
MIIKTFLADDHRLFRDGLRRILAETTDIVVVGEATDGLDALKKMRLGGWDVGLLDVSMPGMNGLEVLQRIMDDDPKHRIL
MLSTYHEDEYAIRAIRAGTSAYLTKNSPTDLLISVIRRLAHGGRYIDPKLAEKLLFDLGPSSTMPRHSALSNRELDVLKL
IAVGISLTEISQKLKLSAKTISTYRARVLEKMGMQNNAQLIRYVAEHKLLE
>Mature_211_residues
MIIKTFLADDHRLFRDGLRRILAETTDIVVVGEATDGLDALKKMRLGGWDVGLLDVSMPGMNGLEVLQRIMDDDPKHRIL
MLSTYHEDEYAIRAIRAGTSAYLTKNSPTDLLISVIRRLAHGGRYIDPKLAEKLLFDLGPSSTMPRHSALSNRELDVLKL
IAVGISLTEISQKLKLSAKTISTYRARVLEKMGMQNNAQLIRYVAEHKLLE

Specific function: Member of the two-component regulatory system UvrY/BarA involved in the regulation of carbon metabolism via the CsrA/CsrB regulatory system. UvrY activates the transcription of the untranslated csrB RNA and of barA, in an autoregulatory loop. Mediates the

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=210, Percent_Identity=36.6666666666667, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1790102, Length=202, Percent_Identity=33.6633663366337, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1786747, Length=204, Percent_Identity=25.9803921568627, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1788521, Length=198, Percent_Identity=30.8080808080808, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1788712, Length=207, Percent_Identity=25.6038647342995, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1787473, Length=181, Percent_Identity=31.4917127071823, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI87082052, Length=114, Percent_Identity=40.3508771929825, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1788546, Length=210, Percent_Identity=28.0952380952381, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23681; Mature: 23681

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIKTFLADDHRLFRDGLRRILAETTDIVVVGEATDGLDALKKMRLGGWDVGLLDVSMPG
CEEEEECCCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHCCCCCEEEEEECCCC
MNGLEVLQRIMDDDPKHRILMLSTYHEDEYAIRAIRAGTSAYLTKNSPTDLLISVIRRLA
CCHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHH
HGGRYIDPKLAEKLLFDLGPSSTMPRHSALSNRELDVLKLIAVGISLTEISQKLKLSAKT
CCCCCCCHHHHHHHHHHCCCCCCCCCHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHH
ISTYRARVLEKMGMQNNAQLIRYVAEHKLLE
HHHHHHHHHHHHCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIIKTFLADDHRLFRDGLRRILAETTDIVVVGEATDGLDALKKMRLGGWDVGLLDVSMPG
CEEEEECCCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHCCCCCEEEEEECCCC
MNGLEVLQRIMDDDPKHRILMLSTYHEDEYAIRAIRAGTSAYLTKNSPTDLLISVIRRLA
CCHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHH
HGGRYIDPKLAEKLLFDLGPSSTMPRHSALSNRELDVLKLIAVGISLTEISQKLKLSAKT
CCCCCCCHHHHHHHHHHCCCCCCCCCHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHH
ISTYRARVLEKMGMQNNAQLIRYVAEHKLLE
HHHHHHHHHHHHCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]