Click here to switch to the map view.

The map label for this gene is cysH1 [H]

Identifier: 82702276

GI number: 82702276

Start: 1320609

End: 1321379

Strand: Direct

Name: cysH1 [H]

Synonym: Nmul_A1147

Alternate gene names: 82702276

Gene position: 1320609-1321379 (Clockwise)

Preceding gene: 82702275

Following gene: 82702277

Centisome position: 41.47

GC content: 55.9

Gene sequence:

>771_bases
TTGGTTGAGGACATGAGCCTGGATCAAAAAATTGCAGAGGTGCGAACCCTGCTCGAGAGGGTGCAGAAAGATTATTTGCC
TGCCACTTTCGCAAACAGTTTCGGCGCTGAGGATATGGTGCTGACCGATCTCATTGCGCGGCATTATCCGGATATCGAAA
TGTTCACATTGGATACCGGACGGCTTCCGCAGGAAACCTATGACCTCATGCAGCAGGTTACCGAGCGGTACGGCATCCGG
ATTCCAGTCTATTTTCCGGATGCTGCCGCAGTGGAAGCGTACGTGGCGCAGAACGGCCCCAATGCGTTTTACGACAGCGT
GGATTTGCGCAAGAAGTGCTGCCACATCCGCAAGGTCGAACCATTGAAACGGGCCTTGAGGGATAAGCGCGCATGGATTA
CCGGTTTGCGCCGGGATCAGGCGCCCACGCGGAAGGGTTTGGTCGAATCGGAGTTCGATGCCGAGAACGGTCTGCAAAAA
TTCAGCCCTTTGCTGGACTGGAGCCAGGCTGACGTGTGGGCGTATCTCAAGCAGTTCGATGTGCCATACAACGCTCTGCA
CGACAAAGGTTACACGAGTATCGGATGCGCTCCTTGCACTCGCGCCATTACCCCCGGTGAGGATGTTCGTGCGGGCCGCT
GGTGGTGGGAGGATCCGGAAATCAAGGAATGTGGCCTGCATCCTGGCAAAAAACGCGGCGCCCATAATATCGCCAGCGCA
ACTACTGCCGGTTCAGGCGCGGCAGTAAAGGATCTGGCTGTTTCAGACTGA

Upstream 100 bases:

>100_bases
GGGTGCGCTGCCGAGGCCGCTTCCCGCGAAGTCAGCGTTGGGACGGGTACCTTCATCGGCAACTGTCTGATTAACTCGAT
GAATGATTGGCCGGGAATGA

Downstream 100 bases:

>100_bases
ATACGGGATCCCGGAAAGCGGGAATAAAAGACATCGGCGGGCACAGTAGGAATAATAAGCAGGGATAGTAGGGACGAAGG
AATTGCGTGGAGCGCCTCCT

Product: phosphoadenosine phosphosulfate reductase

Products: NA

Alternate protein names: 3'-phosphoadenylylsulfate reductase; PAPS reductase, thioredoxin dependent; PAPS sulfotransferase; PAdoPS reductase [H]

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MVEDMSLDQKIAEVRTLLERVQKDYLPATFANSFGAEDMVLTDLIARHYPDIEMFTLDTGRLPQETYDLMQQVTERYGIR
IPVYFPDAAAVEAYVAQNGPNAFYDSVDLRKKCCHIRKVEPLKRALRDKRAWITGLRRDQAPTRKGLVESEFDAENGLQK
FSPLLDWSQADVWAYLKQFDVPYNALHDKGYTSIGCAPCTRAITPGEDVRAGRWWWEDPEIKECGLHPGKKRGAHNIASA
TTAGSGAAVKDLAVSD

Sequences:

>Translated_256_residues
MVEDMSLDQKIAEVRTLLERVQKDYLPATFANSFGAEDMVLTDLIARHYPDIEMFTLDTGRLPQETYDLMQQVTERYGIR
IPVYFPDAAAVEAYVAQNGPNAFYDSVDLRKKCCHIRKVEPLKRALRDKRAWITGLRRDQAPTRKGLVESEFDAENGLQK
FSPLLDWSQADVWAYLKQFDVPYNALHDKGYTSIGCAPCTRAITPGEDVRAGRWWWEDPEIKECGLHPGKKRGAHNIASA
TTAGSGAAVKDLAVSD
>Mature_256_residues
MVEDMSLDQKIAEVRTLLERVQKDYLPATFANSFGAEDMVLTDLIARHYPDIEMFTLDTGRLPQETYDLMQQVTERYGIR
IPVYFPDAAAVEAYVAQNGPNAFYDSVDLRKKCCHIRKVEPLKRALRDKRAWITGLRRDQAPTRKGLVESEFDAENGLQK
FSPLLDWSQADVWAYLKQFDVPYNALHDKGYTSIGCAPCTRAITPGEDVRAGRWWWEDPEIKECGLHPGKKRGAHNIASA
TTAGSGAAVKDLAVSD

Specific function: Reduction of activated sulfate into sulfite [H]

COG id: COG0175

COG function: function code EH; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAPS reductase family. CysH subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789121, Length=210, Percent_Identity=31.9047619047619, Blast_Score=100, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6325425, Length=216, Percent_Identity=32.4074074074074, Blast_Score=97, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011798
- InterPro:   IPR004511
- InterPro:   IPR002500
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01507 PAPS_reduct [H]

EC number: =1.8.4.8 [H]

Molecular weight: Translated: 28856; Mature: 28856

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVEDMSLDQKIAEVRTLLERVQKDYLPATFANSFGAEDMVLTDLIARHYPDIEMFTLDTG
CCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHCCCCEEEEECCC
RLPQETYDLMQQVTERYGIRIPVYFPDAAAVEAYVAQNGPNAFYDSVDLRKKCCHIRKVE
CCCHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCH
PLKRALRDKRAWITGLRRDQAPTRKGLVESEFDAENGLQKFSPLLDWSQADVWAYLKQFD
HHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHC
VPYNALHDKGYTSIGCAPCTRAITPGEDVRAGRWWWEDPEIKECGLHPGKKRGAHNIASA
CCHHHHHCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCHHCCCHHHHHH
TTAGSGAAVKDLAVSD
CCCCCCCHHHHHCCCC
>Mature Secondary Structure
MVEDMSLDQKIAEVRTLLERVQKDYLPATFANSFGAEDMVLTDLIARHYPDIEMFTLDTG
CCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHCCCCEEEEECCC
RLPQETYDLMQQVTERYGIRIPVYFPDAAAVEAYVAQNGPNAFYDSVDLRKKCCHIRKVE
CCCHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCH
PLKRALRDKRAWITGLRRDQAPTRKGLVESEFDAENGLQKFSPLLDWSQADVWAYLKQFD
HHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHC
VPYNALHDKGYTSIGCAPCTRAITPGEDVRAGRWWWEDPEIKECGLHPGKKRGAHNIASA
CCHHHHHCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCHHCCCHHHHHH
TTAGSGAAVKDLAVSD
CCCCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10710307 [H]